Creatine: Very Different For Young & Old People

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What’s the Deal with Creatine?

Creatine is best-known for its use as a sports supplement. It has a few other uses too, usually in the case of helping to treat (or recover from) specific medical conditions.

What actually is it?

Creatine is an organic compound formed from amino acids (mostly l-arginine and lysine, can be l-methionine, but that’s not too important for our purposes here).

We can take it as a supplement, we can get it in our diet (unless we’re vegan, because plants don’t make it; vertebrates do), and we can synthesize it in our own bodies.

What does it do?

While creatine supplements mostly take the form of creatine monohydrate, in the body it’s mostly stored in our muscle tissue as phosphocreatine, and it helps cells produce adenosine triphosphate, (ATP).

ATP is how energy is kept ready to use by cells, and is cells’ immediate go-to when they need to do something. For this reason, it’s highly instrumental in cell repair and rebuilding—which is why it’s used so much by athletes, especially bodybuilders or other athletes that have a vested interest in gaining muscle mass and enjoying faster recovery times.

See: Creatine use among young athletes

However! For reasons as yet not fully known, it doesn’t seem to have the same beneficial effect after a certain age:

Read: Differential response of muscle phosphocreatine to creatine supplementation in young and old subjects

What about the uses outside of sport?

Almost all studies outside of athletic performance have been on animals, despite it being suggested as potentially helpful for many things, including:

  • Alzheimer’s disease
  • Parkinson’s disease
  • Huntington’s disease
  • ischemic stroke
  • epilepsy
  • brain or spinal cord injuries
  • motor neuron disease
  • memory and brain function in older adults

However, research that’s been done on humans has been scant, if promising:

In short: creatine may reduce symptoms and slow the progression of some neurological diseases, although more research in humans is needed, and words such as “promising”, “potential”, etc are doing a lot of the heavy lifting in those papers we just cited.

Is it safe?

It seems so: Creatine supplementation and health variables: a retrospective study

Nor does it appear to create the sometimes-rumored kidney problems, cramps, or dehydration:

Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?

Where can I get it?

You can get it from pretty much any sports nutrition outlet, or you can order online. For example:

Click here to check it out on Amazon!

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  • The Comfort Book – by Matt Haig

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    This book “is what it says on the tin”. Matt Haig, bestselling author of “Reasons to Stay Alive” (amongst other works) is here with “a hug in a book”.

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  • Coughing/Wheezing After Dinner?

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    The After-Dinner Activities You Don’t Want

    A quick note first: our usual medical/legal disclaimer applies here, and we are not here to diagnose you or treat you; we are not doctors, let alone your doctors. Do see yours if you have any reason to believe there may be cause for concern.

    Coughing and/or wheezing after eating is more common the younger or older someone is. Lest that seem contradictory: it’s a U-shaped bell-curve.

    It can happen at any age and for any of a number of reasons, but there are patterns to the distribution:

    Mostly affects younger people:

    Allergies, asthma

    Young people are less likely to have a body that’s fully adapted to all foods yet, and asthma can be triggered by certain foods (for example sulfites, a common preservative additive):

    Adverse reactions to the sulphite additives

    Foods/drinks that commonly contain sulfites include soft drinks, wines and beers, and dried fruit

    As for the allergies side of things, you probably know the usual list of allergens to watch out for, e.g: dairy, fish, crustaceans, eggs, soy, wheat, nuts.

    However, that’s far from an exhaustive list, so it’s good to see an allergist if you suspect it may be an allergic reaction.

    Affects young and old people equally:

    Again, there’s a dip in the middle where this doesn’t tend to affect younger adults so much, but for young and old people:

    Dysphagia (difficulty swallowing)

    For children, this can be a case of not having fully got used to eating yet if very small, and when growing, can be a case of “this body is constantly changing and that makes things difficult”.

    For older people, this can can come from a variety of reasons, but common culprits include neurological disorders (including stroke and/or dementia), or a change in saliva quality and quantity—a side-effect of many medications:

    Hyposalivation in Elderly Patients

    (particularly useful in the article above is the table of drugs that are associated with this problem, and the various ways they may affect it)

    Managing this may be different depending on what is causing your dysphagia (as it could be anything from antidepressants to cancer), so this is definitely one to see your doctor about. For some pointers, though:

    NHS Inform | Dysphagia (swallowing problems)

    Affects older people more:

    Gastroesophagal reflux disease (GERD)

    This is a kind of acid reflux, but chronic, and often with a slightly different set of symptoms.

    GERD has no known cure once established, but its symptoms can be managed (or avoided in the first place) by:

    And of course, don’t smoke, and ideally don’t drink alcohol.

    You can read more about this (and the different ways it can go from there), here:

    NICE | Gastro-oesophageal reflux disease

    Note: this above page refers to it as “GORD”, because of the British English spelling of “oesophagus” rather than “esophagus”. It’s the exact same organ and condition, just a different spelling.

    Take care!

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  • Celery vs Lettuce – Which is Healthier?

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    Our Verdict

    When comparing celery to lettuce, we picked the lettuce.

    Why?

    Let us consider the macros first: lettuce has 2x the protein, but of course the numbers are tiny and probably nobody is eating this for the protein. Both of these salad items are roughly comparable in terms of carbs and fiber, being both mostly water with just enough other stuff to hold their shape. Nominally this section is a slight win for lettuce on account of the protein, but in realistic practical terms, it’s a tie.

    In terms of vitamins, celery has more of vitamins B5 and E, while lettuce has more of vitamins A, B1, B2, B3, B6, B7, B9, C, K, and choline. An easy win for lettuce here.

    In the category of minerals, celery has more calcium, copper, and potassium, while lettuce has more iron, magnesium, manganese, phosphorus, potassium, selenium, and zinc. So, a fair win for lettuce.

    Adding up the sections makes for an overall win for lettuce; of course, enjoy both, though!

    Want to learn more?

    You might like to read:

    Why You’re Probably Not Getting Enough Fiber (And How To Fix It)

    Take care!

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    This is a little flashier in presentation than we usually go for here, but the content is actually very good. Indeed, we’ve featured Jim Kwik before, with different, but also good content—in that case, physical exercises that strengthen the brain.

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  • Which Plant Milk?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Plant-based milks—what’s best?

    You asked us to look at some popular plant milks and their health properties, and we said we’d do a main feature, so here it is!

    We’ll also give a quick nod to environmental considerations at the end too (they might not be quite what you expect!). That said, as a health and productivity newsletter, we’ll be focusing on the health benefits.

    While we can give a broad overview, please note that individual brands may vary, especially in two important ways:

    • Pro: many (most?) brands of plant milks fortify their products with extra vitamins and minerals, especially vitamin D and calcium.
    • Con: some brands also add sugar.

    So, by all means use this guide to learn about the different plants’ properties, and/but still do check labels later.

    Alternatively, consider making your own!

    • Pros: no added sugar + cheaper
    • Cons: no added vitamins and minerals + some equipment required

    Almond milk

    Almond milk is low in carbs and thus good for a carb-controlled diet. It’s also high in vitamin E and a collection of minerals.

    Oat milk

    Oats are one of the healthiest “staple foods” around, and while drinking oat milk doesn’t convey all the benefits, it does a lot. It also has one of the highest soluble fiber contents of any milk, which is good for reducing LDL (bad) cholesterol levels.

    See for example: Consumption of oat milk for 5 weeks lowers serum cholesterol and LDL cholesterol in free-living men with moderate hypercholesterolemia

    Coconut milk

    Coconut has a higher fat content than most plant milks, but also contains medium-chain triglycerides (MCTs). These raise HDL (good) cholesterol levels.

    Read the study: How well do plant based alternatives fare nutritionally compared to cow’s milk?

    Hemp milk

    Being made from hemp seeds that contain a lot of protein and healthy fats (including omega-3 and omega-6), hemp milk packs a nutritious punch. It’s carb-free. It’s also THC-free, in case you were wondering, which means no, it does not have psychoactive effects.

    Pea milk

    It’s very high in protein, and contains an array of vitamins and minerals. It’s not very popular yet, so there isn’t as much research about it. This 2021 study found that it had the nutritional profile the closest to cow’s milk (beating soy by a narrow margin) and praised it as a good alternative for those with a soy allergy.

    This is Research Review Monday so we try to stick to pure science, but for your interest… here’s an interesting pop-science article (ostensibly in affiliation with the pea milk brand, Ripple) about the nutritional qualities of their pea milk specifically, which uses particularly nutrient-dense yellow peas, plus some extra vitamin and mineral fortifications:

    Read: Ripple Milk: 6 Reasons Why You Should Try Pea Milk

    Soy milk

    Perhaps the most popular plant milk, and certainly usually the cheapest in stores. It’s high in protein, similar to cow’s milk. In fact, nutritionally, it’s one of the closest to cow’s milk without involving cows as a middleman. (Did you know three quarters of all soy in the world is grown to feed to livestock, not humans? Now you do).

    And no, gentlemen-readers, it won’t have any feminizing effects. The human body can’t use the plant estrogens in soy for that. It does give some isoflavone benefits though, which are broadly good for everyone’s health. See for example this research review with 439 sources of its own:

    Read: Soy and Health Update: Evaluation of the Clinical and Epidemiologic Literature

    Quick note on flavor: nut milks have the flavor of the nut they were made from. Coconut milk tastes of coconut. The other milks listed above don’t have much of a flavor—which in many cases may be what you want.

    Note on environmental considerations:

    A lot of us try to be as socially responsible as reasonably possible in our choices, so this may be an influencing factor. In a nutshell:

    • Oats and Soy are generally grown as vast monocrops, and these are bad for the environment
      • They are still better for the environment than cow’s milk though, as for example most soy is grown to feed to cows, not humans. So including cows in the process means four times as much monocrop farming, plus adds several other environmental issues that are beyond the scope of this newsletter.
    • Almonds are particularly resource-intensive when it comes to water use.
      • Still nowhere near as much as cows, though.
    • Peas are grown in places that naturally have very high rainfall, so are a good option here. Same generally goes for rice, which didn’t make the cut today. (Nor did hazelnuts, sorry—we can only include so much!)
    • Hemp is by far and away the most environmentally friendly, assuming it is grown in a climate naturally conducive to such.
    • Making plant milk at home is usually most environmentally friendly, depending on where your ingredients came from.
    • Literally any plant milk is much more environmentally friendly than cow’s milk.

    See the science for yourself: Reducing food’s environmental impacts through producers and consumers

    See also (if you like graphs and charts): Environmental footprints of dairy and plant-based milks

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  • Are Electrolyte Supplements Worth It?

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    When To Take Electrolytes (And When We Shouldn’t!)

    Any sports nutrition outlet will sell electrolyte supplements. Sometimes in the form of sports drinks that claim to be more hydrating than water, or tablets that can be dissolved in water to make the same. How do they work, and should we be drinking them?

    What are electrolytes?

    They’re called “electrolytes” because they are ionized particles (so, they have a positive or negative electrical charge, depending on which kind of ion they are) that are usually combined in the form of salts.

    The “first halves” of the salts include:

    • Sodium
    • Potassium
    • Calcium
    • Magnesium

    The “second halves” of the salts include:

    • Chloride
    • Phosphate
    • Bicarbonate
    • Nitrate

    It doesn’t matter too much which way they’re combined, provided we get what we need. Specifically, the body needs them in a careful balance. Too much or too little, and bad things will start happening to us.

    If we live in a temperate climate with a moderate lifestyle and a balanced diet, and have healthy working kidneys, usually our kidneys will keep them all in balance.

    Why might we need to supplement?

    Firstly, of course, you might have a dietary deficiency. Magnesium deficiency in particular is very common in North America, as people simply do not eat as much greenery as they ideally would.

    But, also, you might sweat out your electrolytes, in which case, you will need to replace them.

    In particular, endurance training and High Intensity Interval Training are likely to prompt this.

    However… Are you in a rush? Because if not, you might just want to recover more slowly:

    ❝Vigorous exercise and warm/hot temperatures induce sweat production, which loses both water and electrolytes. Both water and sodium need to be replaced to re-establish “normal” total body water (euhydration).

    This replacement can be by normal eating and drinking practices if there is no urgency for recovery.

    But if rapid recovery (<24 h) is desired or severe hypohydration (>5% body mass) is encountered, aggressive drinking of fluids and consuming electrolytes should be encouraged to facilitate recovery❞

    Source: Fluid and electrolyte needs for training, competition, and recovery

    Should we just supplement anyway, as a “catch-all” to be sure?

    Probably not. In particular, it is easy to get too much sodium in one’s diet, let alone by supplementation.And, oversupplementation of calcium is very common, and causes its own health problems. See:

    To look directly to the science on this one, we see a general consensus amongst research reviews: “this is complicated and can go either way depending on what else people are doing”:

    Well, that’s not helpful. Any clearer pointers?

    Yes! Researchers Latzka and Mountain put together a very practical list of tips. Rather, they didn’t put it as a list, but the following bullet points are information extracted directly from their abstract, though we’ve also linked the full article below:

    • It is recommended that individuals begin exercise when adequately hydrated.
      • This can be facilitated by drinking 400 mL to 600 mL of fluid 2 hours before beginning exercise and drinking sufficient fluid during exercise to prevent dehydration from exceeding 2% body weight.
    • A practical recommendation is to drink small amounts of fluid (150-300 mL) every 15 to 20 minutes of exercise, varying the volume depending on sweating rate.
      • During exercise lasting less than 90 minutes, water alone is sufficient for fluid replacement
      • During prolonged exercise lasting longer than 90 minutes, commercially available carbohydrate electrolyte beverages should be considered to provide an exogenous carbohydrate source to sustain carbohydrate oxidation and endurance performance.
    • Electrolyte supplementation is generally not necessary because dietary intake is adequate to offset electrolytes lost in sweat and urine; however, during initial days of hot-weather training or when meals are not calorically adequate, supplemental salt intake may be indicated to sustain sodium balance.

    Source: Water and electrolyte requirements for exercise

    Bonus tip:

    We’ve talked before about the specific age-related benefits of creatine supplementation, but if you’re doing endurance training or HIIT, you might also want to consider a creatine-electrolyte combination sports drink (even if you make it yourself):

    Creatine-electrolyte supplementation improves repeated sprint cycling performance: a double-blind randomized control study

    Where can I get electrolyte supplements?

    They’re easy to find in any sports nutrition store, or you can buy them online; here’s an example product on Amazon for your convenience

    You can also opt for natural and/or homemade electrolyte drinks:

    Healthline | 8 Healthy Drinks Rich in Electrolytes

    Enjoy!

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