Too Much Or Too Little Testosterone?

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One Man’s Saw Palmetto Is Another Woman’s Serenoa Repens…

Today we’re going to look at saw palmetto. So, first:

What is it?

Saw palmetto is a type of palm native to the southeastern United States. Its scientific name is “Serenoa repens”, so if that name appears in studies we cite, it’s the same thing. By whichever name, it’s widely enjoyed as a herbal supplement.

Why do people take it?

Here’s where it gets interesting, because people take it for some completely opposite reasons…

Indeed, searching for it on the Internet will cause Google to suggest “…for men” and “…for women” as the top suggestions.

That’s because it works on testosterone, and testosterone can be a bit of a double-edged sword, so some people want to increase or decrease certain testosterone-related effects on their body.

And it works for both! Here be science:

  • Testosterone (henceforth, “T”) is produced in the human body.
    • Yes, all human bodies, to some extent.
  • An enzyme called 5-alpha-reductase converts T in to DHT (dihydrogen testosterone)
  • DHT is a much more potent androgen (masculinizing agent) than T alone, such that its effects are often unwanted, including:
    • Enlarged prostate (if you have one)
    • Hair loss (especially in men)
    • New facial hair growth (usually unwanted by women)
      • Women are more likely to get this due to PCOS and/or the menopause

To avoid those effects, you really want less of your T to be converted into DHT.

Saw palmetto is a 5α-reductase inhibitor, so if you take it, you’ll have less DHT, and you’ll consequently lose less hair, have fewer prostate problems, etc.

Read: Determination of the potency of a novel saw palmetto supercritical CO2 extract (SPSE) for 5α-reductase isoform II inhibition using a cell-free in vitro test system

^The above study showed that saw palmetto extract performed comparably to finasteride. Finasteride is the world’s main go-to prescription drug for treating enlarged prostate and/or hair loss.

See also: Natural Hair Supplement: Friend or Foe? Saw Palmetto, a Systematic Review in Alopecia

Hair today… Growing tomorrow!

So, what was that about increasing T levels?

Men usually suffer declining T levels as they get older, with a marked drop around the age of 45. With lower T comes lower energy, lower mood, lower libido, erectile dysfunction, etc.

Guess what… It’s T that’s needed for those things, not DHT. So if you block the conversion of T to DHT, you’ll have higher blood serum T levels, higher energy, higher mood, higher libido, and all that.

Read: Standardized Saw Palmetto Extract Directly and Indirectly Affects Testosterone Biosynthesis and Spermatogenesis

(the above assumes you have testicles, without which, your T levels will certainly not increase)

Saw Palmetto Against Enlarged Prostate?

With higher DHT levels in mid-late life, prostate enlargement (benign prostatic hyperlasia) can become a problem for many men. The size of that problem ranges from urinary inconvenience (common, when the prostate presses against the bladder) to prostate cancer (less common, much more serious). Saw palmetto, like other 5α-reductase inhibitors such as finasteride, may be used to prevent or treat this.

Wondering how safe/reliable it is? We found a very high-quality fifteen-year longitudinal observational study of the use of saw palmetto, and it found:

❝The 15 years’ study results suggest that taking S. repens plant extract continuously at a daily dose of 320 mg is an effective and safe way to prevent the progression of benign prostatic hyperplasia.❞

Read: 15 years’ survey of safety and efficacy of Serenoa repens extract in benign prostatic hyperplasia patients with risk of progression

Want a second opinion? We also found a 10-year study (by different researchers with different people taking it), which reached the same conclusion:

❝The results of study showed the absence of progression, both on subjective criteria (IPSS, and QoL scores), and objective criteria (prostate volume, the rate of urination, residual urine volume). Furthermore, patients had no undesirable effects directly related to the use of this drug.❞

  • IPSS = International Prostate Symptom Score
  • QoL = Quality of Life

Read: The results of the 10-year study of efficacy and safety of Serenoa repens extract in patients at risk of progression of benign prostatic hyperplasia

But wait a minute; I, a man over the age of 45 with potentially declining T levels but a fabulous beard, remember that you said just a minute ago that saw palmetto is used by women to avoid having facial hair; I don’t want to lose mine!

You won’t. Once your facial hair follicles were fully developed and activated during puberty, they’ll carry on doing what they do for life. That’s no longer regulated by hormones once they’re up and running.

The use of saw palmetto can only be used to limit facial hair if caught early—so it’s more useful at the onset of menopause, for those who have (or will have) such, or else upon the arrival of PCOS symptoms or hirsuitism from some other cause.

Take The Test!

Do you have a prostate, and would like to know your IPSS score, and what that means for your prostate health?

Take The Test Here!

(takes 1 minute, no need to pee or go probing for anything)

Bottom Line on Saw Palmetto

  • It blocks the conversion of T into DHT
  • It will increase blood serum T levels, thus boosting mood, energy, libido, etc in men (who typically have more T, but whose T levels decline with age)
  • It will decrease DHT levels, thus limiting hair loss (especially in men) and later-life new facial hair growth (especially in women).
  • It can be used to prevent or treat prostate enlargement
  • Bonus: it’s a potent antioxidant and thus reduces general inflammation (in everyone)

Want To Try Saw Palmetto?

We don’t sell it (or anything else), but for your convenience…

Click here to check out saw palmetto on Amazon!

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    Manage hormonal fluctuations with intermittent fasting, anti-inflammatory diet, and more. This book is for peri-menopausal and post-menopausal women, and anyone with an endocrine system. Take control of your hormones now!

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  • Fruit & Veg In The Fridge: Pros & Cons

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s Q&A Day at 10almonds!

    Have a question or a request? We love to hear from you!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    ❝What effect does refrigeration have on the nutritional value of fruit and vegetables??❞

    It’s difficult to give a single definitive answer, because naturally there are a lot of different fruits and vegetables, and a lot of different climates. The answer may be different for tomatoes in Alaska vs bananas in Arizona!

    However, we can still generalize at least somewhat

    Refrigeration will generally slow down any degradation process, and in the case of fruit and vegetables, that can mean slowing down their “ripening” too, as applicable.

    However…

    Refrigeration will also impede helpful bioactivity too, and that includes quite a list of things.

    Here’s a good study that’s quite illustrative; we’d summarize the conclusions but the rather long title already does that nicely:

    Storage of Fruits and Vegetables in Refrigerator Increases their Phenolic Acids but Decreases the Total Phenolics, Anthocyanins and Vitamin C with Subsequent Loss of their Antioxidant Capacity

    So, this really is a case of “there are pros and cons, but probably more cons on balance”.

    In practical terms, a good take-away from this can be twofold:

    1. don’t keep fruit and veg in the fridge unless the ambient temperature really requires it
    2. if the ambient temperature does require it, it’s best to get the produce in fresh each day if that’s feasible, to minimize time spent in the fridge

    An extra thing not included there: often when it comes to the spoilage of fruit and veg, the problem is that it respires and oxidizes; reducing the temperature does lower the rate of those, but often a far better way is to remove the oxygen. So for example, if you get carried away and chop too many carrot batons for your hummus night, then putting them in a sealed container can go a long way to keeping them fresh.

    See also: How Does the Nutritional Value of Fruits and Vegetables Change Over Time?

    Enjoy!

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  • Coffee, From A Blood Sugar Management Perspective

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our favorite French biochemist (Jessie Inchauspé) is back, and this time, she’s tackling a topic near and dear to this writer’s heart: coffee ☕💕

    What to consider

    Depending on how you like your coffee, some or all of these may apply to you:

    • Is coffee healthy? Coffee is generally healthy, reducing the risk of type 2 diabetes by improving fat burning in the liver and protecting beta cells in the pancreas.
    • Does it spike blood sugars? Usually not so long as it’s black and unsweetened. Black coffee can cause small glucose spikes in some people due to stress-induced glucose release, but only if it contains caffeine.
    • When is it best to drink it? Drinking coffee after breakfast, especially after a poor night’s sleep, can actually reduce glucose and insulin spikes.
    • What about milk? All milks cause some glucose and insulin spikes. While oat milk is generally healthy, for blood sugar purposes unsweetened nut milks or even whole cow’s milk (but not skimmed; it needs the fat) are better options as they cause smaller spikes.
    • What about sweetening? Adding sugar to coffee, especially on an empty stomach, obviously leads to large glucose spikes. Alternative sweeteners like stevia or sweet cinnamon are fine substitutes.

    For more details on all of those things, plus why Kenyan coffee specifically may be the best for blood sugars, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like to read:

    Take care!

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  • Muir Glen Organic vs First Field Original – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing Muir Glen Organic Ketchup to First Field Original Ketchup, we picked the First Field.

    Why?

    This one was a little unfair to you, as you can’t turn them around to read the ingredients here. But the point we want to share the most today is: you have to turn them around and read the ingredients! You absolutely cannot rely on appearances!

    While the Muir Glen Organic may have a very “greenwashed” aesthetic going on and the word “organic” is more eye-catching than any other word on the label, it contains 4x as much sugar and 4x as much sodium.

    Side-by-side, they have, per tablespoon:

    First Field Original: 1g sugar, 60mg sodium
    Muir Glen Organic: 4g sugar, 240mg sodium

    But what about the importance of being organic?

    Well, we have one more surprise for you: the First Field ketchup is organic too, non-GMO, and contains no added concentrates either.

    This isn’t an ad for First Field (by all means enjoy their products or don’t; we’re not invested), but it is a heartfelt plea to always check the backs of products and read the labels, because fronts of products can’t be relied upon at all.

    I’m sure we all get caught out sometimes, but the less often, the better!

    PS: we write this, of course, before seeing the results of your voting. Maybe it won’t be a “Muir Glen Organic” sweep in the polls. But either way, it’s a call to vigilance, and a “very good, carry on” to everyone who does this already

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  • How to Do the Work – by Dr. Nicole LaPera

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    We have reviewed some self-therapy books before, and they chiefly have focused on CBT and mindfulness, which are great. This one’s different.

    Dr. Nicole LaPera has a bolder vision for what we can do for ourselves. Rather than giving us some worksheets for unraveling cognitive distortions or clearing up automatic negative thoughts, she bids us treat the cause, rather than the symptom.

    For most of us, this will be the life we have led. Now, we cannot change the parenting style(s) we received (or didn’t), get a redo on childhood, avoid mistakes we made in our adolescence, or face adult life with the benefit of experience we gained right after we needed it most. But we can still work on those things if we just know how.

    The subtitle of this book promsies that the reader can/will “recognise your patterns, heal from your past, and create your self”.

    That’s accurate, for the content of the book and the advice it gives.

    Dr. LaPera’s focus is on being our own best healer, and reparenting our own inner child. Giving each of us the confidence in ourself; the love and care and/but also firm-if-necessary direction that a (good) parent gives a child, and the trust that a secure child will have in the parent looking after them. Doing this for ourselves, Dr. LaPera holds, allows us to heal from traumas we went through when we perhaps didn’t quite have that, and show up for ourselves in a way that we might not have thought about before.

    If the book has a weak point, it’s that many of the examples given are from Dr. LaPera’s own life and experience, so how relatable the specific examples will be to any given reader may vary. But, the principles and advices stand the same regardless.

    Bottom line: if you’d like to try self-therapy on a deeper level than CBT worksheets, this book is an excellent primer.

    Click here to check out How To Do The Work, and empower yourself to indeed do the work!

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  • Yoga Nidra Made Easy – by Dr. Uma Dinsmore-Tuli and Nirlipta Tuli

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    We’ve reviewed books about yoga before, and about sleep. This one’s different.

    It’s about a yogic practice that can be used to promote restful sleep—or just be a non-sleeping exercise that nonetheless promotes relaxation and recuperation.

    While yoga nidra is as somatic as it is psychological, its corporeal aspects are all explored in a lying-down-on-one’s-back state. This isn’t a book of stretches and poses and such—those are great, but are simply not needed for this practice.

    The authors explain, step-by-step, simply and clearly, how to practice yoga nidra, and get out of it what you want to (there are an assortment of possible outcomes, per your preference; there are options to choose along the way).

    A lot of books about yoga, even when written in English, contain a lot of Sanskrit terms. This one doesn’t. And, that difference goes a long way to living up to the title of making this easy, for those of us who regrettably don’t read even transliterated Sanskrit.

    Bottom line: if ever you struggle to relax, struggle to sleep, or struggle to find your get-up-and-go, this book provides all you need to engage in this very restorative practice!

    Click here to check out Yoga Nidra Made Easy, and learn this restorative tool for yourself!

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  • When BMI Doesn’t Measure Up

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    When BMI Doesn’t Quite Measure Up

    Last month, we did a “Friday Mythbusters” edition of 10almonds, tackling many of the misconceptions surrounding obesity. Amongst them, we took a brief look at the usefulness (or lack thereof) of the Body Mass Index (BMI) scale of weight-related health for individuals. By popular subscriber request, we’re now going to dive a little deeper into that today!

    The wrong tool for the job

    BMI was developed as a tool to look at large-scale demographic trends, stemming from a population study of white European men, who were for the purpose of the study (the widescale health of the working class in that geographic area in that era), considered a reasonable default demographic.

    In other words: as a system, it’s now being used in a way it was never made for, and the results of that misappropriation of an epidemiological tool for individual health are predictably unhelpful.

    If you want to know yours…

    Here’s the magic formula for calculating your BMI:

    • Metric: divide your weight in kilograms by your height in square meters
    • Imperial: divide your weight in pounds by your height in square inches and then multiply by 703

    “What if my height doesn’t come in square meters or square inches, because it’s a height, not an area?”

    We know. Take your height and square it anyway. If this seems convoluted and arbitrary, yes, it is.

    But!

    While on the one hand it’s convoluted and arbitrary… On the other hand, it’s also a gross oversimplification. So, yay for the worst of both worlds?

    If you don’t want to grab a calculator, here’s a quick online tool to calculate it for you.

    So, how did you score?

    According to the CDC, a BMI score…

    • Under 18.5 is underweight
    • 18.5 to 24.9 is normal
    • 25 to 29.9 is overweight
    • 30 and over is obese

    And, if we’re looking at a representative sample of the population, where the representation is average white European men of working age, that’s not a bad general rule of thumb.

    For the rest of us, not so representative

    BMI is a great and accurate tool as a rule of thumb, except for…

    Women

    An easily forgotten demographic, due to being a mere 51% of the world’s population, women generally have a higher percentage of body fat than men, and this throws out BMI’s usefulness.

    If pregnant or nursing

    A much higher body weight and body fat percentage—note that these are two things, not one. Some of the extra weight will be fat to nourish the baby; some will be water weight, and if pregnant, some will be the baby (or babies!). BMI neither knows nor cares about any of these things. And, this is a big deal, because BMI gets used by healthcare providers to judge health risks and guide medical advice.

    People under the age of 16 or over the age of 65

    Not only do people below and above those ages (respectively) tend to be shorter—which throws out the calculations and mean health risks may increase before the BMI qualifies as overweight—but also:

    • BMI under 23 in people over the age of 65 is associated with a higher health risk
    • A meta-analysis showed that a BMI of 27 was the best in terms of decreased mortality risk for the over-65 age group

    This obviously flies in the face of conventional standards regards BMI—as you’ll recall from the BMI brackets we listed above.

    Read the science: BMI and all-cause mortality in older adults: a meta-analysis

    Athletic people

    A demographic often described in scientific literature as “athletes”, but that can be misleading. When we say “athletes”, what comes to mind? Probably Olympians, or other professional sportspeople.

    But also athletic, when it comes to body composition, are such people as fitness enthusiasts and manual laborers. Which makes for a lot more people affected by this!

    Athletic people tend to have more lean muscle mass (muscle weighs more than fat), and heavier bones (can’t build strong muscles on weak bones, so the bones get stronger too, which means denser)… But that lean muscle mass can actually increase metabolism and help ward off many of the very same things that BMI is used as a risk indicator for (e.g. heart disease, and diabetes). So people in this category will actually be at lower risk, while (by BMI) getting told they are at higher risk.

    If not white

    Physical characteristics of race can vary by more than skin color, relevant considerations in this case include, for example:

    • Black people, on average, not only have more lean muscle mass and less fat than white people, but also, have completely different risk factors for diseases such as diabetes.
    • Asian people, on average, are shorter than white people, and as such may see increased health risks before BMI qualifies as overweight.
    • Hispanic people, on average, again have different physical characteristics that throw out the results, in a manner that would need lower cutoffs to be even as “useful” as it is for white people.

    Further reading on this: BMI and the BIPOC Community

    In summary:

    If you’re an average white European working-age man, BMI can sometimes be a useful general guide. If however you fall into one or more of the above categories, it is likely to be inaccurate at best, if not outright telling the opposite of the truth.

    What’s more useful, then?

    For heart disease risk and diabetes risk both, waist circumference is a much more universally reliable indicator. And since those two things tend to affect a lot of other health risks, it becomes an excellent starting point for being aware of many aspects of health.

    Pregnancy will still throw off waist circumference a little (measure below the bump, not around it!), but it will nevertheless be more helpful than BMI even then, as it becomes necessary to just increase the numbers a little, according to gestational month and any confounding factors e.g. twins, triplets, etc. Ask your obstetrician about this, as it’s beyond the scope of today’s newsletter!

    As to what’s considered a risk:
    • Waist circumference of more than 35 inches for women
    • Waist circumference of more than 40 inches for men

    These numbers are considered applicable across demographics of age, sex, ethnicity, and lifestyle.

    Source: Waist circumference as a vital sign in clinical practice: a Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity

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