The “Love Drug”

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Get PEA-Brained!

Today we’ll be looking at phenylethylamine, or PEA, to its friends.

Not to be mistaken for the related amino acid phenylalanine! Both ultimately have effects on the dopaminergic system, but the process and benefits are mostly quite different.

We thought we’d do this one in the week of Valentine’s Day, because of its popular association with love:

❝Phenylethylamine (PEA), an amphetamine-like substance that has been alluringly labeled the “chemical of love,” makes the best case for the love-chocolate connection since it has been shown that people in love may actually have higher levels of PEA in their brain, as surmised from the fact that their urine is richer in a metabolite of this compound. In other words, people thrashing around in the throes of love pee differently from others.❞

Source: Office for Science and Society | The Chemical of Love

What is it?

It’s an amino acid. Because we are mammals, we can synthesize it inside our bodies, so it’s not considered an “essential amino acid”, i.e. one that we need to get from our diet. It is found in some foods, though, including:

  • Other animals, especially other mammals
  • Various beans, legumes, nuts, seeds. In particular almonds, soybeans, lentils, and chickpeas score highly
  • Fermented foods
  • Chocolate (popular lore holds this to be a good source of PEA; science finds it to be a fair option, but not in the same ballpark as the other items)

Fun fact: the reason Marvel’s Venom has a penchant for eating humans and chocolate is (according to the comics) because phenylethylamine is an essential amino acid for it.

What does it do for us?

It’s a Central Nervous System (CNS) stimulant, and also helps us synthesize critical neurotransmitters such as dopamine, norepinephrine (adrenaline) and serotonin:

β-Phenylethylamine Alters Monoamine Transporter Function via Trace Amine-Associated Receptor 1: Implication for Modulatory Roles of Trace Amines in Brain

It works similarly, but not identically, to amphetamines:

Amphetamine potentiates the effects of β-phenylethylamine through activation of an amine-gated chloride channel

Is it safe?

We normally do this after the benefits, but “it works similarly to amphetamines” may raise an eyebrow or two, so let’s do it here:

  • It is recommended to take no more than 500mg/day, with 100mg–500mg being typical doses
  • It is not recommended to take it at all if you have, or have a predisposition to, any kind of psychotic disorder (especially schizophrenia, or bipolar disorder wherein you sometimes experience mania)
    • This isn’t a risk for most people, but if you fall into the above category, the elevated dopamine levels could nudge you into a psychotic/manic episode that you probably don’t want.

See for example: Does phenylethylamine cause schizophrenia?

There are other contraindications too, so speak with your doctor/pharmacist before trying it.

On the other hand, if you are considering ADHD medication, then phenylethylamine could be a safer thing to try first, to see if it helps, before going to the heavy guns of actual amphetamines (as are commonly prescribed for ADHD). Same goes for depression and antidepressants.

What can I expect from PEA?

More dopamine, norepinephrine, and serotonin. Mostly the former two. Which means, you can expect stimulation.

For focus and attention, it’s so effective that it has been suggested (as we mentioned above) as a safer alternative to ADHD meds:

β-phenylethylamine, a small molecule with a large impact

…and may give similar benefits to people without ADHD, namely improved focus, attention, and mental stamina:

Integrative Psychiatry | The Many Health Benefits of Phenylethylamine (PEA) – The Brain’s Natural Stimulant

It also improves mood:

❝Phenylethylamine (PEA), an endogenous neuroamine, increases attention and activity in animals and has been shown to relieve depression in 60% of depressed patients. It has been proposed that PEA deficit may be the cause of a common form of depressive illness.

Effective dosage did not change with time. There were no apparent side effects. PEA produces sustained relief of depression in a significant number of patients, including some unresponsive to the standard treatments. PEA improves mood as rapidly as amphetamine but does not produce tolerance.

~ Dr. Sabelli et al.

Source: Sustained antidepressant effect of PEA replacement

Where can I get it?

We don’t sell it, but here is an example product on Amazon for your convenience 😎

Enjoy!

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  • Chickpeas vs Black-Eyed Peas – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing chickpeas to black-eyed peas, we picked the chickpeas.

    Why?

    In terms of macros, chickpeas have more protein, carbs, and fiber, the ratio of the latter two also giving them the lower glycemic index. An easy win for chickpeas.

    In the category of vitamins, chickpeas have more of vitamins B2, B6, C, E, K, and choline, while black-eyed peas have more of vitamins B1, B5, and B9. Another victory for chickpeas.

    When it comes to minerals, things are even more pronounced: chickpeas have more calcium, copper, iron, manganese, phosphorus, potassium, selenium, and zinc, while black-eyed peas have (barely) more magnesium. An overwhelming win for chickpeas.

    Adding up the sections makes for a very evident overall win for chickpeas; as ever, do enjoy either or both though; diversity is good!

    Want to learn more?

    You might like to read:

    What’s Your Plant Diversity Score?

    Enjoy!

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  • Heal Your Nervous System – by Dr. Linnea Passaler

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    This book focuses on the oft-overlooked connection between nervous system dysregulation (i.e. sympathetic nervous system dominance, keeping the brain in “may have to fight for my life at any moment” mode) and the many symptoms—mental and physical—that can arise as a result.

    While there is a lot of theory explained in here, there’s practicality too, providing the reader with tools to assess our own levels of nervous system dysregulation and what factors affect that.

    In particular in that category, a lot of value is delivered in terms of practical guidance on avoiding common pitfalls in the healing journey. Dr. Passaler discusses the four biggest mistakes people make when attempting to heal, and gives clear strategies to sidestep each of them, with exercises to do and habits to implement.

    Another thing that sets this book apart from many of its genre is her emphasis on the importance of sequencing healing practices in the right order. By offering a structured approach, the book helps us implement healing practices without getting overwhelmed or hitting the proverbial brick wall and getting frustrated, which makes a big difference.

    The style is easy-to-understand pop-science, albeit with a reassuring 20 pages of references at the back.

    Bottom line: if you feel like “peace of mind” is something that’s always just out of reach, this book can help you to get where you need to be, physically as well as mentally.

    Click here to check out Heal Your Nervous System, and get things into much better order!

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  • Beating Sleep Apnea

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Healthier, Natural Sleep Without Obstruction!

    Obstructive Sleep Apnea, the sleep disorder in which one periodically stops breathing (and thus wakes up) repeatedly through the night, affects about 25% of men and 10% of women:

    Prevalence of Obstructive Sleep Apnea Syndrome: A Single-Center Retrospective Study

    Why the gender split?

    There are clues that suggest it is at least partially hormonal: once women have passed menopause, the gender split becomes equal.

    Are there other risk factors?

    There are few risk other factors; some we can’t control, and some we can:

    • Being older is riskier than being younger
    • Being overweight is riskier than not being overweight
    • Smoking is (what a shock) riskier than not smoking
    • Chronic respiratory diseases increase risk, for example:
      • Asthma
      • COPD
      • Long COVID*—probably. The science is young for this one so far, so we can’t say for sure until more research has been done.
    • Some hormonal conditions increase risk, for example:

    *However, patients already undergoing Continuous Positive Airway Pressure (CPAP) treatment for obstructive sleep apnea may have an advantage when fighting a COVID infection:

    Prolonged Effects of the COVID-19 Pandemic on Sleep Medicine Services—Longitudinal Data from the Swedish Sleep Apnea Registry

    What can we do about it?

    Avoiding the above risk factors, where possible, is great!

    If you are already suffering from obstructive sleep apnea, then you probably already know about the possibility of a CPAP device; it’s a mask that one wears to sleep, and it does what its name says (i.e. it applies continuous positive airway pressure), which keeps the airway open.

    We haven’t tested these, but other people have, so here are some that the Sleep Foundation found to be worthy of note:

    Sleep Foundation | Best CPAP Machines of 2024

    What can we do about it that’s not CPAP?

    Wearing a mask to sleep is not everyone’s preferred way to do things. There are also a plethora of surgeries available, but we’ll not review those, as those are best discussed with your doctor if necessary.

    However, some lifestyle changes can help, including:

    • Lose weight, if overweight. In particular, having a collar size under 16” for women or under 17” for men, is sufficient to significantly reduce the risk of obstructive sleep apnea.
    • Stop smoking, if you smoke. This one, we hope, is self-explanatory.
    • Stop drinking alcohol, or at least reduce intake, if you drink. People who consume alcohol tend to have more frequent, and longer, incidents of obstructive sleep apnea. See also: How To Reduce Or Quit Drinking
    • Avoid sedatives and muscle relaxants, if it is safe for you to do so. Obviously, if you need them to treat some other condition you have, talk this through with your doctor. But basically, they can contribute to the “airway collapses on itself” by reducing the muscular tension that keeps your airway the shape it’s supposed to be.
    • Sleep on your side, not your back. This is just plain physics, and a matter of wear the obstruction falls.
    • Breathe through your nose, not through your mouth. Initially tricky to do while sleeping, but the more you practice it while awake, the more it becomes possible while asleep.
    • Consider a nasal decongestant before sleep, if congestion is a problem for you, as that can help too.

    For more of the science of these, see:

    Cultivating Lifestyle Transformations in Obstructive Sleep Apnea

    There are more medical options available not discussed here, too:

    American Sleep Apnea Association | Sleep Apnea Treatment Options

    Take care!

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    Hepatitis B is a viral infection that can cause liver disease in people of any age or background. Vaccination is 95 percent effective against the virus. But in recent years, false claims, rumors, and myths about the hepatitis B vaccine have become increasingly common.

    Here’s everything you need to know about the lifesaving hepatitis B vaccine.

    What is hepatitis B?

    Hepatitis B is a liver infection caused by the hepatitis B virus. The virus attacks the liver, causing severe short-term and long-term infections. 

    Short-term hepatitis B infections may cause “fever, fatigue, loss of appetite, nausea, vomiting, jaundice (yellow skin or eyes, dark urine, clay-colored bowel movements), and pain in the muscles, joints, and stomach,” according to the Centers for Disease Control and Prevention. 

    A long-term hepatitis B infection occurs when the virus stays in the body beyond the initial infection, causing chronic illness. Hepatitis B infections become chronic in 90 percent of infected infants, half of infected young children, and between 5 to 10 percent of infected adults. 

    “Most people who go on to develop chronic hepatitis B do not have symptoms, but it is still very serious and can lead to liver damage (cirrhosis), liver cancer, and death. Chronically infected people can spread hepatitis B virus to others, even if they do not feel or look sick themselves,” says the CDC. 

    How does the hepatitis B virus spread?

    The hepatitis B virus is spread through body fluids, including blood, semen, and saliva. It can also be transmitted from birthing parent to child during pregnancy and childbirth. 

    “While hepatitis B is an infection that lives in bodily fluids, it can survive outside the human body for several days, which means that sharing contaminated household products is a possible source of infection,” said Dr. Christopher Labos, a McGill University cardiologist and epidemiologist, in a 2019 article.

    In 2022, over 250 million people worldwide had chronic hepatitis B, and 1.1 million died from the disease. Most of the deaths were from liver damage and liver cancer. Less than 15 percent of people living with hepatitis B have been diagnosed. 

    How well does the vaccine protect against hepatitis B?

    Hepatitis B vaccination is up to 95 percent effective, providing lasting—and possibly lifelong—protection against the virus. Depending on when the first dose is given, the complete vaccine series consists of two to three doses. 

    The vaccine is most effective for infants and children. The CDC recommends that infants receive it at birth for the most protection. 

    The first dose is followed by two to three additional doses administered before 18 months. Children, adolescents, and adults who weren’t vaccinated as infants should also receive the vaccine. 

    Vaccination is particularly important for high-risk groups, including health workers and those who are in close contact with individuals living with chronic hepatitis B, people who use intravenous drugs, and people receiving blood transfusions, dialysis, or organ transplants. 

    Is the vaccine safe?

    Vaccines against hepatitis B were first developed in the 1980s, and they have been proven safe for decades. They have a low risk of serious side effects and are safe enough to be given to newborns, pregnant people, and immunocompromised people.

    We also know hepatitis B vaccines work: “Between 1990 (about the time when universal hepatitis B vaccinations started) and 2006, the rate of hepatitis B infection fell by 81 percent to the lowest level ever recorded, and the decline was greatest among children,” added Labos. 

    Hepatitis B rates have continued to decline across all age groups, with the U.S. exceeding its goal of reducing new hepatitis B infections by 20 percent.

    Why do doctors recommend the vaccine for babies?

    Hepatitis B vaccination helps protect infants from a lifetime of potentially life-threatening infections and complications. Nine out of 10 unvaccinated infants infected with hepatitis B will develop chronic infections, which increases their risk of liver failure and liver cancer. 

    The hepatitis B vaccine is administered at birth to help prevent the virus from being transmitted from birthing parent to child. It also helps protect infants who might be in close contact with someone with hepatitis B. This is particularly important because most people who have hepatitis are undiagnosed. 

    Have more questions? Talk to your health care provider to learn more about hepatitis B vaccination.

    This article first appeared on Public Good News and is republished here under a Creative Commons license.

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  • Peaches vs Plums – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing peaches to plums, we picked the peaches.

    Why?

    Both are great! But there is a clear winner out of these two botanically-similar fruits:

    In terms of macronutrients they are very similar. Peaches have slightly more protein and plums have slightly more carbs, but the numbers are close enough to make no meaningful difference; they’re both mostly water.

    They’re also not too far from each other in the category of vitamins; peaches have more of vitamins B2, B3, B5, E, and choline, while plums have more of vitamins B1, B6, B9, C, and K. They’re equal on vitamin A, by the way, and the vitamins they do differ in, differ by around the same margins, so this category is a clear tie.

    When it comes to minerals, however, peaches win easily with more copper, iron, magnesium, manganese, phosphorus, potassium, selenium, and zinc. The two fruits are equal on calcium, and plum is not higher in any minerals.

    While they already won easily because of the mineral situation, it should be noted that peaches also have the lower glycemic index. But honestly, plums are fine too; peaches are just even lower.

    So: enjoy both, but if you’re going to pick one, peaches boast the most!

    Want to learn more?

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    Take care!

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  • Getting Flexible, Starting As An Adult: How Long Does It Really Take?

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    Aleks Brzezinska didn’t start stretching until she was 21, and here’s what she found:

    We’ll not stretch the truth

    A lot of stretching programs will claim “do the splits in 30 days” or similar, and while this may occasionally be true, usually it’ll take longer.

    Brzezinska started stretching seriously when she was 21, and made significant flexibility gains between the ages of 21 and 23 with consistent practice. Since then, she’s just maintained her flexibility.

    There are facts that affect progress significantly, such as:

    • Anatomy: body structure, age, and joint flexibility do influence flexibility; starting younger and/or having hypermobile joints does make it easier.
    • Consistency: regular practice (2–3 times a week) is crucial, but avoid overdoing it, especially when sore.
    • Lifestyle: weightlifting, running, and similar activities can tighten muscles, making flexibility harder to achieve.
    • Hydration: staying hydrated is important for muscle flexibility.

    She also recommends incorporating a variety of different stretching types, rather than just one method, for example passive stretching, active stretching, Proprioceptive Neuromuscular Facilitation (PNF) stretching, and mobility work.

    For more on each of these, enjoy:

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    Jasmine McDonald’s Ballet Stretching Routine

    Take care!

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