Recognize The Early Symptoms Of Parkinson’s Disease

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Parkinson’s disease is a degenerative condition with wide-reaching implications for health. While there is currently no known cure, there are treatments, so knowing about it sooner rather than later is important.

Spot The Signs

There are two main kinds of symptoms, motor and non-motor.

Motor symptoms include:

  • trembling that occurs when muscles are relaxed; often especially visible in the fingers
  • handwriting changes—not just because of the above, but also often getting smaller
  • blank expression, on account of fewer instruction signals getting through to the face
  • frozen gait—especially difficulty starting walking, and a reduced arm swing

Non-motor symptoms include:

  • loss of sense of smell—complete, or a persistent reduction of
  • sleepwalking, or sleep-talking, or generally acting out dreams while asleep
  • constipation—on an ongoing basis
  • depression/anxiety, especially if there was no prior history of these conditions

For more detail on each of these, as well as what steps you might want to take, check out what Dr. Luis Zayas has to say:

Click Here If The Embedded Video Doesn’t Load Automatically!

Want to learn more?

You might also like to read:

Citicoline vs Parkinson’s (And More)

Take care!

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    • Licorice, Digestion, & Hormones

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      Let’s Take A Look At Licorice…

      Licorice, as a confectionary, is mostly sugar and is useless for medicinal purposes.

      Licorice (Glycyrrhiza sp., most often Glycyrrhiza glabra), in the form of either the root extract (which can be taken as a supplement, or used topically) or the whole root (which can be taken as a powder/capsule, or used to make tea), is a medicinal plant with a long history of use.

      How well-evidenced is it for its popular uses?

      Licorice for digestion

      In this case, it is more accurate to say that it combats indigestion, including acid reflux and ulcerative colitis:

      Systematic Review on Herbal Preparations for Controlling Visceral Hypersensitivity in Functional Gastrointestinal Disorders ← licorice was a top-tier performer in this review

      Network pharmacology mechanisms and experimental verification of licorice in the treatment of ulcerative colitis ← looking at the mechanism of action; ultimately they concluded that “licorice improves ulcerative colitis, which may be related to the activation of the Nrf2/PINK1 signaling pathway that regulates autophagy.“

      Licorice vs menopause symptoms

      This one, while a popular use, isn’t so clear. Here’s a study that examines the compounds in licorice (in this case, Glycyrrhiza uralensis) that interact with estrogen receptors, notes that the bioavailability is poor, and proposes, tests, and recommends a way to make it more bioavailable:

      Development of an Improved Menopausal Symptom-Alleviating Licorice (Glycyrrhiza uralensis) by Biotransformation Using Monascus albidulus

      On the other hand, it is established that it will lower serum testosterone levels, which may make it beneficial for menopause and/or PCOS:

      Polycystic ovaries and herbal remedies: A systematic review

      Licorice for men

      You may be wondering: what about for men? Well, the jury is out on whether it meaningfully reduces free testosterone levels:

      Licorice consumption and serum testosterone in healthy men

      See also:

      Liquorice in moderate doses does not affect sex steroid hormones of biological importance although the effect differs between the genders

      And finally, it may (notwithstanding its disputed effect on testosterone itself) be useful as a safer alternative to finasteride (an antiandrogen mostly commonly used to treat benign prostatic hyperplasia, also used to as a hair loss remedy), since it (like finasteride) modulates 5α-reductase activity (this enzyme converts testosterone to the more potent dihydrogen testosterone, DHT), without lowering sperm count:

      Therapeutic role of Glycyrrhiza Uralensis fisher on benign prostatic hyperplasia through 5 alpha reductase regulation and apoptosis

      Licorice for the skin

      As well as its potentially estrogenic activity, its anti-inflammatory and antioxidant powers make it comparable to hydrocortisone cream for treating eczema, psoriasis, and other such skin conditions:

      New Herbal Biomedicines for the Topical Treatment of Dermatological Disorders

      Is it safe?

      It is “generally recognized as safe”, as the classification goes.

      However, consumed in excess it can cause/worsen hypertension, and other contraindications include if you’re on blood thinners, or have kidney problems.

      As ever, this is a non-exhaustive list, so do speak with your doctor/pharmacist to be sure.

      Want to try some?

      We don’t sell it, but here for your convenience is an example product on Amazon

      Enjoy!

      Share This Post

    • Natto, Taurine + Black Pepper, And Other Game-Changers

      10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

      It’s Q&A Day at 10almonds!

      Have a question or a request? You can always hit “reply” to any of our emails, or use the feedback widget at the bottom!

      In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

      As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

      So, no question/request too big or small

      ❝Loved the info on nuts; of course I always eat pecans, which didn’t make the list of healthy nuts!❞

      Dear subscriber, pardon the paraphrase of your comment—somehow it got deleted and now exists only in this writer’s memory. However, to address it:

      Pecans are great too! We can’t include everything in every article (indeed, we got another feedback the same day saying the article was too long), but we love when you come to us with stuff for us to look at and write about (seriously, writer here: the more you ask, the easier it makes my job), so let’s talk pecans for a moment:

      Pecans would have been number six on our list if we’d have written more!

      Like many nuts, they’ve an abundance of healthy fats, fiber, vitamins, and minerals.

      They’re particularly good for zinc, which is vital for immune function, healing (including normal recovery after normal exercise), and DNA synthesis (so: anti-aging).

      Pecans are also great for reducing LDL (“bad” cholesterol) and triglycerides (which are also bad for heart health); check it out:

      Pecan-Enriched Diets Alter Cholesterol Profiles and Triglycerides in Adults at Risk for Cardiovascular Disease in a Randomized, Controlled Trial

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    • An apple cider vinegar drink a day? New study shows it might help weight loss

      10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

      Made from fermented apples and naturally high in acetic acid, apple cider vinegar has been popular in recent years for its purported health benefits – from antibacterial properties to antioxidant effects and potential for helping manage blood sugars.

      Its origins as a health tonic stretch much further back. Hippocrates used it to treat wounds, fever and skin sores.

      An experimental study, released today, looks into whether apple cider vinegar could be effective for weight loss, reduce blood glucose levels and reduce blood lipids (cholesterol and triglycerides).

      The results suggest it could reduce all three – but it might not be as simple as downing an apple cider vinegar drink a day.

      What did they do?

      A group of scientists in Lebanon did a double-blinded, randomised, clinical trial in a group of overweight and obese young people aged from 12–25 years.

      Researchers randomly placed 30 participants in one of four groups. The participants were instructed to consume either 5, 10 or 15ml of apple cider vinegar diluted into 250ml of water each morning before they ate anything for 12 weeks. A control group consumed an inactive drink (a placebo) made (from lactic acid added to water) to look and taste the same.

      Typically this sort of study provides high quality evidence as it can show cause and effect – that is the intervention (apple cider vinegar in this case) leads to a certain outcome. The study was also double-blinded, which means neither the participants or the scientists involved with collecting the data knew who was in which group.

      So, what did they find?

      After a period of three months apple cider vinegar consumption was linked with significant falls in body weight and body mass index (BMI). On average, those who drank apple cider vinegar during that period lost 6–8kg in weight and reduced their BMI by 2.7–3 points, depending on the dose. They also showed significant decreases in the waist and hip circumference.

      The authors also report significant decreases in levels of blood glucose, triglycerides, and cholesterol in the apple cider groups. This finding echoes previous studies. The placebo group, who were given water with lactic acid, had much smaller decreases in weight and BMI. There were also no significant decreases in blood glucose and blood lipids.

      From animal studies, it is thought the acetic acid in apple cider vinegar may affect the expression of genes involved in burning fats for energy. The new study did not explore whether this mechanism was involved in any weight loss.

      Is this good news?

      While the study appears promising, there are also reasons for caution.

      Firstly, study participants were aged from 12 to 25, so we can’t say whether the results could apply to everyone.

      The statistical methods used in the study don’t allow us to confidently say the same amount of weight loss would occur again if the study was done again.

      And while the researchers kept records of the participants’ diet and exercise during the study, these were not published in the paper. This makes it difficult to determine if diet or exercise may have had an impact. We don’t know whether participants changed the amount they ate or the types of food they ate, or whether they changed their exercise levels.

      The study used a placebo which they tried to make identical in appearance and taste to the active treatment. But people may still be able to determine differences. Researchers may ask participants at the end of a study to guess which group they were in to test the integrity of the placebo. Unfortunately this was not done in this study, so we can’t be certain if the participants knew or not.

      Finally, the authors do not report whether anyone dropped out of the study. This could be important and influence results if people who did not lose weight quit due to lack of motivation.

      open glass of liquid with cloudy substance at bottom, surrounded by apples
      Is that you mother? The enzymes in apple cider vinegar might be health-giving.
      Shutterstock

      Any other concerns?

      Apple cider vinegar is acidic and there are concerns it may erode tooth enamel. This can be a problem with any acidic beverages, including fizzy drinks, lemon water and orange juice.

      To minimise the risk of acid erosion some dentists recommend the following after drinking acidic drinks:

      • rinsing out your mouth with tap water afterwards
      • chewing sugar-free gum afterwards to stimulate saliva production
      • avoiding brushing your teeth immediately after drinking because it might damage the teeth’s softened top layer
      • drink with a straw to minimise contact with the teeth.
      woman holds glass of water and has full cheeks
      Rinsing with water could prevent acid damaging your teeth.
      Shutterstock

      Down the hatch?

      This study provides us with some evidence of a link between apple cider vinegar and weight loss. But before health professionals can recommend this as a weight loss strategy we need bigger and better conducted studies across a wider age range.

      Such research would need to be done alongside a controlled background diet and exercise across all the participants. This would provide more robust evidence that apple cider vinegar could be a useful aid for weight loss.

      Still, if you don’t mind the taste of apple cider vinegar then you could try drinking some for weight loss, alongside a healthy balanced and varied dietary intake. This study does not suggest people can eat whatever they like and drink apple cider vinegar as a way to control weight. The Conversation

      Evangeline Mantzioris, Program Director of Nutrition and Food Sciences, Accredited Practising Dietitian, University of South Australia

      This article is republished from The Conversation under a Creative Commons license. Read the original article.

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      • The Inflamed Mind – by Dr. Edward Bullmore

        10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

        Firstly, let’s note that this book was published in 2018, so the “radical new” approach is more like “tried and tested and validated” now.

        Of course, inflammation in the brain is also linked to Alzheimer’s, Parkinson’s, and other neurodegenerative disorders, but that’s not the main topic here.

        Dr. Bullmore, a medical doctor, psychiatrist, and neuroscientist with half the alphabet after his name, knows his stuff. We don’t usually include author bio information here, but it’s also relevant that he has published more than 500 scientific papers and is one of the most highly cited scientists worldwide in neuroscience and psychiatry.

        What he explores in this book, with a lot of hard science made clear for the lay reader, is the mechanisms of action of depression treatments that aren’t just SSRIs, and why anti-inflammatory approaches can work for people with “treatment-resistant depression”.

        The book was also quite prescient in its various declarations of things he expects to happen in the field in the next five years, because they’ve happened now, five years later.

        Bottom line: if you’d like to understand how the mind and body affect each other in the cases of inflammation and depression, with a view to lessening either or both of those things, this is a book for you.

        Click here to check out The Inflamed Mind, and take good care of yours!

        Don’t Forget…

        Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

        Learn to Age Gracefully

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      • Almonds vs Walnuts – Which is Healthier?

        10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

        Our Verdict

        When comparing almonds to walnuts, we picked the almonds.

        Why?

        It wasn’t just our almond bias, but it was close!

        In terms of macros, the main important differences are:

        • Almonds are higher in protein
        • Walnuts are higher in fats (they are healthy fats)

        So far, so even.

        In terms of vitamins, both are rich in many vitamins; mostly the same ones. However, walnuts have more of most of the B vitamins (except for B2 and B3, where almonds win easily), and almonds have more vitamin E by several orders of magnitude.

        So far, so balanced.

        Almonds have slightly more choline.

        Almonds have a better mineral profile, with more of most minerals that they both contain, and especially, a lot more calcium.

        Both nuts have [sometimes slightly different, but] comparable benefits against diabetes, cancer, neurodegeneration, and other diseases.

        In summary

        This one’s close. After balancing out the various “almonds have this but walnuts have that” equal-but-different benefits, we’re going to say almonds take first place by virtue of the better mineral profile, and more choline.

        But: enjoy both!

        Learn more

        You might like this previous article of ours:

        Why You Should Diversify Your Nuts

        Take care!

        Don’t Forget…

        Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

        Learn to Age Gracefully

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      • Blueberry & Banana Collagen Baked Oats

        10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

        Good news for vegans/vegetarians! While we include an optional tablespoon of collagen powder in this recipe, the whole recipe is already geared around collagen synthesis, so it’s very collagen-boosting even with just the plants, providing collagen’s building blocks of protein, zinc, and vitamins C and D (your miraculous body will use these to assemble the collagen inside you).

        You will need

        • 2 cups oats, whence the protein and zinc
        • 1 cup milk (your preference what kind; we recommend almond for flavor; whether you choose plant or animal though, it should be fortified with vitamin D)
        • 2 bananas, peeled and mashed
        • 4 oz blueberries, whence the vitamin C (frozen is fine) (chopped dried apricots are also a fine substitute if that’s more convenient)
        • 1 oz flaked almonds, whence the protein and zinc
        • 1 tbsp pumpkin seeds, whence the protein and zinc
        • 1 tbsp flax seeds, whence the protein and zinc
        • Optional: 1 tbsp maple syrup
        • Optional: 1 tbsp collagen powder, dissolved in 1 oz hot water

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        (we suggest you read everything at least once before doing anything)

        1) Preheat the oven to 350℉ / 180℃.

        2) Mix the oats with 2 cups boiling water; allow to stand for 10–15 minutes, and then drain any excess water.

        3) Mix the mashed bananas with the remaining ingredients except the milk and blueberries, stirring thoroughly.

        4) Add the softened oats, and stir those in thoroughly too.

        5) Add the milk and blueberries, in that order, stirring gently if using fresh blueberries, lest they get crushed.

        6) Pour the mixture into an 8″ square cake tin that you have lined with baking paper, and smooth the top.

        7) Bake for about 40 minutes or until firm and golden brown. Allow to cool; it will firm up more while it does.

        8) Cut into squares or bars, and serve or store for later.

        Enjoy!

        Want to learn more?

        For those interested in some of the science of what we have going on today:

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        Take care!

        Don’t Forget…

        Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

        Learn to Age Gracefully

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