Delay Ageing – by Dr. Colin Rose
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
Note: the title is spelled that way because it is British English. We generally write in US English here at 10almonds, but we’ll first quote directly from Dr. Rose as written:
❝I have written Delay Ageing because there is some very important recent University research on ageing and age related illness that deserves to be made accessible to a general audience.❞
What is this research? Well, there’s quite a lot over its 300-odd pages (exact number depends on the edition and whether we count end matter), and most of it is tweaks and refinements on things with which you’ll probably be at least brushingly familiar if you’re a regular 10almonds reader.
Dr. Rose addresses the nine hallmarks of aging, of which there are ten, ranging from such things as “telomeres get shorter” and “DNA accumulates damage”, to “stem cells become exhausted” and “cells fail to communicate properly”, and asks the question “what if we were to target all these things simultaneously?”.
Rather than going for drugs on drugs on drugs (half of them to deal with undesired side effects of the previous ones), Dr. Cole leaves no stone unturned to find lifestyle interventions that will improve each of these, even if just a little. Because, all those “little” improvements add up and even compound, and on the flipside, mean that factors of aging aren’t adding up and compounding so much or so quickly anymore.
The rather broad umbrella of “lifestyle interventions” obviously includes food under its auspices, and with it, nutraceuticals. So to give one example, if you’re taking a fisetin supplement (a natural senolytic agent), you’ll find science vindicating that here. And much more.
The style is… Less pop-science and more “textbook written for laypersons”, and you may be thinking “isn’t that the same?” and the difference is that the textbook has a lot less polish and finesse, but often more precise information.
Bottom line: if you’d like to combat aging on 10 different fronts with easily implementable lifestyle interventions, and know exactly what is doing what and how, then this is the book for you.
Don’t Forget…
Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!
Recommended
Learn to Age Gracefully
Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:
-
The Dangers Of Fires, Floods, & Having Your Hair Washed
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
It’s a dangerous business, going out of your door… And this week’s news round-up looks at 5 reasons why that might be:
Superspreading like wildfire
Environmental health risks are a big topic these days, with our changing climate. As for wildfires? Some of the risks are obvious: burning to death or choking to death in the smoke—but even upon surviving the seemingly worst, more threats remain that themselves can still kill.
Those threats include that both burns and smoke inhalation can cause acute and chronic changes in the immune system. Specifically: changes for the worse. The mechanisms by which this happens depend on the nature of any burns received, and in the case of smoke, what exactly was in the smoke. Now, there is no kind of smoke that is healthy to inhale, but definitely some kinds are a lot worse than others, and let’s just say, people’s homes contain a lot of plastic.
Additionally, if you think someone coughing near you spreads germs, imagine how far germs can be spread by miles-high, miles-wide billowing hot air.
In short, there’s a lot going on and none of it is good, and we’ve barely had room to summarise here, so…
Read in full: Wildfires ignite infection risks by weakening the body’s immune defenses and spreading bugs in smoke
Related: What’s Lurking In Your Household Air?
A flood of diseases
*record scratch*
Environmental health risks are a big topic these days, with our changing climate. As for floods? Some of the risks are obvious: drowning to death or having your house washed away—but even upon surviving the seemingly worst, more threats remain that themselves can still kill.
Those threats include increases in deaths from infectious and parasitic diseases, and respiratory diseases in general. Simply, a place that has been waterlogged, even if it seems “safe” now, is not a healthy place to be, due to bacteria, viruses, fungi, and more. In fact, it even increases all-cause mortality, because being healthy in such a place is simply harder:
Read in full: Linked to higher mortality rates, large floods emerge as an urgent public health concern
Related: Dodging Dengue In The US
Don’t lose your head
Visiting the hairdresser is not something that most people consider a potential brush with death—your hairdresser is probably not Sweeney Todd, after all. However…
There is an issue specifically with getting your hair washed there. Backwash basins—the sink things into which one rests one’s head at a backwards tilt—create an awkward angle for the cervical vertebrae and a sudden reduction in blood flow to the brain can cause a stroke, with the risk being sufficiently notable as to have its own name in scientific literature: beauty parlor stroke syndrome (BPSS).
❝While research suggests BPSS is most likely to occur in women over 50—and previous history of narrowing or thinning of blood vessels and arthritis of the spinal column in the neck are particular risk factors—it could happen to anyone regardless of age or medical history.❞
Read in full: The hidden health risk of having your hair washed
Related: Your Stroke Survival Plan
The smartwatch wristbands that give you cancer
It’s about the PFAS content. The article doesn’t discuss cancer in detail, just mentioning the increased risk, but you can read about the link between the two in our article below.
Basically, if your smartwatch wristband is a) not silicone and b) waterproof anyway, especially if it’s stain-resistant (as most are designed to be, what with wearing it next to one’s skin all the time while exercising, and not being the sort of thing one throws in the wash), then chances are it has PFAS levels much higher than normally found in consumer goods or clothing.
You can read more about how to identify the risks, here:
Read in full: Smartwatch bands can contain high levels of toxic PFAS, study finds
Related: PFAS Exposure & Cancer: The Numbers Are High
The cows giving milk with a little extra
Bird flu (HPAI) is now not the only flu epidemic amongst cattle in the US, and not only that, but rather than “merely” colonizing the lungs and upper respiratory tracts, in this case the virus (IAV) is thriving in the mammary glands, meaning that yes, it gets dispensed into the milk, and so far scientists are simply scrambling to find better ways to vaccinate the cattle, in the hopes that the milk will not be so risky because yes, it is currently a “reservoir and transmission vector” for the virus.
There are, however, barriers to creating those vaccines:
Read in full: Unexpected viral reservoir: influenza A thrives in cattle mammary glands
Related: Cows’ Milk, Bird Flu, & You
Take care!
Share This Post
-
10 Mistakes To Sabotage Your Ozempic Progress
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
Ozempic has a good reputation for getting reliable results, but there are ways to mess it up:
It’s not just inject-and-go
We’ll not keep the 10 ways a secret; they are:
- Increasing the dose too quickly: avoid cranking doses up too high too quickly, to prevent severe nausea, appetite suppression, and muscle loss. It’s worth being aware that high doses without proper management can lead to metabolic health disasters.
- Pushing through side effects: severe nausea or vomiting means you probably have an unhelpfully high dose; consult your prescribing doctor—it’s easy to feel “more is better; I don’t want to have less!”, but there really is a sweet spot, and if you’re not in it, then adjustments are needed in order to find it.
- Eating nutritionally scant food: reducing the quantity of unhealthy food isn’t enough—please prioritize nutrient-rich foods instead. Remember, “it’s not the calories in your food; it’s the food in your calories”.
- Consuming fried food and refined carbs: their general metabolic woes aside, fried foods and ultra-refined carbs can exacerbate nausea and other side effects, so it really is best to skip them. The good news is that Ozempic will help overcome those cravings more easily.
- Neglecting muscle protection: especially women, especially middle-aged or older, are at higher risk of osteoporosis and should maintain muscle mass (strong muscles and strong bones go together, by necessity). So, eat protein and do resistance training!
- Assuming it’s a monotherapy: GLP-1 drugs work best as part of a holistic protocol, including proper nutrition, strength training, and hormone therapy if appropriate.
- Not addressing metabolic health first: GLP-1 drugs are less effective in people with poor baseline metabolic health, so there’s a bit of a catch-22 here, but it’s important to be aware of. Fortunately, Ozempic and adopting a healthy lifestyle will each make the other work better.
- Neglecting comprehensive treatment plans: in other words, going through the motions of a holistic protocol and then expecting Ozempic to do all the work.
- Upping doses to overcome plateaus: plateaus often signal other issues (e.g. lack of protein, no strength training), so do address these before increasing dosage.
- Lack of collaboration with doctors: the human body is complex, and what’s going on metabolically is complex too, so there’s a lot a layperson can easily miss. For that matter, there’s a lot that doctors can easily miss too, but more heads are better than one.
For more on all of these, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like:
5 Ways To Naturally Boost The Ozempic Effect
Take care!
Share This Post
-
Rebalancing Dopamine (Without “Dopamine Fasting”)
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
Rebalancing Dopamine (Without “Dopamine Fasting”)
Credit Steve Fisch This is Dr. Anna Lembke. She’s a professor of psychiatry at Stanford, and chief of the Stanford Addiction Medicine Dual Diagnosis Clinic—as well as running her own clinical practice, and serving on the board of an array of state and national addiction-focused organizations.
Today we’re going to look at her work on dopamine management…
Getting off the hedonic treadmill
For any unfamiliar with the term, the “hedonic treadmill” is what happens when we seek pleasure, enjoy the pleasure, the pleasure becomes normalized, and now we need to seek a stronger pleasure to get above our new baseline.
In other words, much like running on a reciprocal treadmill that just gets faster the faster we run.
What Dr. Lembke wants us to know here: pleasure invariably leads to pain
This is not because of some sort of extrinsic moral mandate, nor even in the Buddhist sense. Rather, it is biology.
Pleasure and pain are processed by the same part of the brain, and if we up one, the other will be upped accordingly, to try to keep a balance.
Consequently, if we recklessly seek “highs”, we’re going to hit “lows” soon enough. Whether that’s by drugs, sex, or just dopaminergic habits like social media overuse.
Dr. Lembke’s own poison of choice was trashy romance novels, by the way. But she soon found she needed more, and more, and the same level wasn’t “doing it” for her anymore.
So, should we just give up our pleasures, and do a “dopamine fast”?
Not so fast!
It depends on what they are. Dopamine fasting, per se, does not work. We wrote about this previously:
Short On Dopamine? Science Has The Answer
However, when it comes to our dopaminergic habits, a short period (say, a couple of weeks) of absence of that particular thing can help us re-find our balance, and also, find insight.
Lest that latter sound wishy-washy: this is about realizing how bad an overuse of some dopaminergic activity had become, the better to appreciate it responsibly, going forwards.
So in other words, if your poison is, as in Dr. Lembke’s case, trashy romance novels, you would abstain from them for a couple of weeks, while continuing to enjoy the other pleasures in life uninterrupted.
Substances that create a dependency are a special case
There’s often a popular differentiation between physical addictions (e.g. alcohol) and behavioral addictions (e.g. video games). And that’s fair; physiologically speaking, those may both involve dopamine responses, but are otherwise quite different.
However, there are some substances that are physical addictions that do not create a physical dependence (e.g. sugar), and there are substances that create a physical dependence without being addictive (e.g. many antidepressants)
See also: Addiction and physical dependence are not the same thing
In the case of anything that has created a physical dependence, Dr. Lembke does not recommend trying to go “cold turkey” on that without medical advice and supervision.
Going on the counterattack
Remember what we said about pleasure and pain being processed in the same part of the brain, and each rising to meet the other?
While this mean that seeking pleasure will bring us pain, the inverse is also true.
Don’t worry, she’s not advising us to take up masochism (unless that’s your thing!). But there are very safe healthy ways that we can tip the scales towards pain, ultimately leading to greater happiness.
Cold showers are an example she cites as particularly meritorious.
As a quick aside, we wrote about the other health benefits of these, too:
A Cold Shower A Day Keeps The Doctor Away?
Further reading
Want to know more? You might like her book:
Dopamine Nation: Finding Balance in the Age of Indulgence
Enjoy!
Share This Post
Related Posts
-
How to Eat 30 Plants a Week – by Hugh Fearnley-Whittingstall
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
If you’re used to eating the same two fruits and three vegetables in rotation, the “gold standard” evidence-based advice to “eat 30 different plants per week” can seem a little daunting.
Where this book excels is in reminding the reader to use a lot of diverse plants that are readily available in any well-stocked supermarket, but often get forgotten just because “we don’t buy that”, so it becomes invisible on the shelf.
It’s not just a recipe book (though yes, there are plenty of recipes here); it’s also advice about stocking up and maintaining that stock, advice on reframing certain choices to inject a little diversity into every meal without it become onerous, meal-planning rotation advice, and a lot of recipes that are easy but plant-rich, for example “this soup that has these six plants in it”, etc.
He also gives, for those eager to get started, “10 x 3 recipes per week to guarantee your 30”, in other words, 10 sets of 3 recipes, wherein each set of 3 recipes uses >30 different plants between them, such that if we have each of these set-of-three meals over the course of the week, then what we do in the other 4–18 meals (depending on how many meals per day you like to have) is all just a bonus.
The latter is what makes this book an incredibly stress-free approach to more plant-diverse eating for life.
Bottom line: if you want to be able to answer “do you get your five-a-day?” with “you mean breakfast?” because you’ve already hit five by breakfast each day, then this is the book for you.
Click here to check out How To Eat 30 Plants A Week, and indeed eat 30+ different plants per week!
Don’t Forget…
Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!
Learn to Age Gracefully
Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:
-
Slow-Cooker Moroccan Tagine
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
Tagine (طاجين) (tā-jīn) is a traditional dish named after, well, the traditional dish that it’s cooked in. Here’s an example tagine pot on Amazon. It’s a very nifty bit of kit, and while it’s often used for cooking over charcoal, one of its features is that if you have a hot sunny day, you can just leave it out in the sun and it will cook the contents nicely. Today though, we’re going to assume you don’t have one of these, and are going to give instructions for cooking a tagine-style dish with a slow cooker, which we’re going to assume you do have.
You will need
- 2 large red onions, finely chopped
- 2 large red peppers, cut into 1″ chunks
- 2 large zucchini, cut into ½” chunks
- 1 large eggplant, cut into ½” chunks
- 3 cups tomato passata
- 2 cups cooked chickpeas
- 16 pitted Medjool dates, chopped
- ½ bulb garlic, finely chopped
- 1 tbsp ras el-hanout
- A little extra virgin olive oil
Method
(we suggest you read everything at least once before doing anything)
1) Let your slow cooker heat up while you chop the things that need chopping
2) Add a splash of olive oil to the slow cooker; ensure the base is coated and there’s a little oil spare in there too; a thin coat to the base plus a couple of tbsp should do it nicely.
3) Add the onions and garlic, and leave for an hour.
4) Add the passata, dates, ras el-hanout, stir it and leave for an hour.
5) Add the chickpeas, peppers, and eggplant; stir it and leave for an hour.
6) Add the zucchini, stir it and leave for an hour.
7) Serve—it goes great with its traditional pairing of wholegrain couscous, but if you prefer, you can use our tasty versatile rice. In broader culinary terms, serving it with any carb is fine.
Enjoy!
Want to learn more?
For those interested in some of the science of what we have going on today:
- Level-Up Your Fiber Intake! (Without Difficulty Or Discomfort)
- What Matters Most For Your Heart? Eat More (Of This) For Lower Blood Pressure
- Our Top 5 Spices: How Much Is Enough For Benefits?
Take care!
Don’t Forget…
Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!
Learn to Age Gracefully
Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:
-
Walking… Better.
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
Walking… Better.
We recently reviewed “52 Ways To Walk” by Annabel Streets. You asked us to share some more of our learnings from that book, and… Obviously we can’t do all 52, nor go into such detail, but here are three top tips inspired by that book…
Walk in the cold!
While cold weather is often seen as a reason to not walk, in fact, it has numerous health benefits, the most exciting of which might be:
Walking in the cold causes us to convert white and yellow fat into the healthier brown fat. If you didn’t know about this, neither did scientists until about 15 years ago.
In fact, scientists didn’t even know that adult humans could even have brown adipose tissue! It was really quite groundbreaking.
In case you missed it: The Changed Metabolic World with Human Brown Adipose Tissue: Therapeutic Visions
Work while you walk!
Obviously this is only appropriate for some kinds of work… but if in your life you have any kind of work that is chiefly thinking, a bunch of it can be done while walking.
Open your phone’s note-taking app, lock the screen and pocket your phone, and think on some problem that you need to solve. Whenever you have an “aha” moment, take out your phone and make a quick note on the go.
For that matter, if you have the money and space (or are fortunate to have an employer disposed towards facilitating such), you could even set up a treadmill desk… At worst, it wouldn’t harm your work (and it’ll be a LOT better than sitting for so long).
Walk within an hour of waking!
No, this doesn’t mean that if you don’t get out of the house within 60 minutes you say “Oh no, missed the window, guess it’s a day in today”
But it does mean: in the evening, make preparations to head out first thing in the morning. Set out your clothes and appropriate footwear, find your flask to fill with the beverage of your choice in the morning and set that with them.
Then, when morning arrives… do your morning necessaries (e.g. some manner of morning ablutions and perhaps a light breakfast), make that drink for your flask, and hit the road.
Why? We’ll tell you a secret:
You ever wondered why some people seem to be more able to keep a daylight-regulated circadian rhythm than others? It’s not just about smartphones and coffees…
This study found that getting sunlight (not electric light, not artificial sunlight, but actual sunlight, from the sun, even if filtered through partial cloud) between 08:30—09:00 resulted in higher levels of a protein called PER2. PER2 is critical for setting circadian rhythms, improving metabolism, and fortifying blood vessels.
Besides, on a more simplistic level, it’s also a wonderful and energizing start to a healthy and productive day!
Read: Beneficial effects of daytime light exposure on daily rhythms, metabolic state and affect
Don’t Forget…
Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!
Learn to Age Gracefully
Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:
