
Are You Making This Alcohol Mistake?
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The famous “small glass of red per day” is, as is quite well-established now in science, but not so much in popular culture, known to be not a good idea.
What most people don’t know
Rethinking “One Drink a Day”:
- Outdated beliefs and flawed studies:
- The idea that “one drink a day is healthy” stems from flawed associative studies that included…
- unhealthy former heavy drinkers in the zero-drinks category, and
- healthy older individuals who continued light drinking due to good health, not because alcohol contributed to it, in the drinkers category
- In other words, they looked at former alcoholics whose health was ruined by drinking and said “aha, non-drinkers have bad health”, and looked at the survivors of survivorship bias and said “aha, light drinking is the key to good health”. Which of course is terrible science propped up by terrible abuse of statistics propped up by shoddy methodology.
- The idea that “one drink a day is healthy” stems from flawed associative studies that included…
- New research findings:
- A 2022 UK Biobank Study showed that even one drink a day leads to brain shrinkage, neuron death, and cognitive decline.
- Another study on CVD disproved the notion that light drinking benefits heart health once confounding variables were removed.
- There are plenty more, and at 10almonds we’ve done a main feature about it, but for now, you get the idea.
Some other things you should know:
Ethanol and acetaldehyde damage neurons responsible for impulse control, judgment, motor coordination, and memory formation, leading to cognitive decline. The feeling of being drunk results from the suppression and damage of these neurons. But while the drunk feeling wears off, the damage to neurons does not.
Alcohol causes cumulative DNA damage in neurons, accelerates brain aging, and prevents the formation of new neurons, similar to a slow, gradual stroke.
Broader Health Impacts of Alcohol
We’ve said it before, and we’ll say it again: alcohol is bad for pretty much everything.
Here are some examples mentioned in the video:
- Neurodegenerative diseases: heavy drinking increases the risk of Alzheimer’s, particularly in those genetically predisposed.
- Sleep disruption: alcohol reduces deep, restful sleep and hampers the brain’s natural detox process overnight, contributing to morning grogginess.
- Inflammation and immune suppression: alcohol increases inflammation, exacerbates autoimmune diseases (like psoriasis and arthritis), and weakens immune function.
- Cancer risk: alcohol is classified as a Group 1 carcinogen by the International Agency for Research on Cancer, linked to various cancers, especially breast cancer. Even light drinking increases breast cancer risk.
- Hormonal imbalances: in women, alcohol heightens PMS symptoms, reduces fertility, and increases testosterone. In men, it lowers sperm quality and disrupts hormones.
For more on all of these and more, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like to read:
- Can We Drink To Good Health? ← this is mostly about red wine and heart health
- How To Reduce Or Quit Alcohol ← this is about the more general reasons to quit, and how to do so
- What Happens To Your Body When You Stop Drinking Alcohol ← a realistic timeline of recovery
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America Worries About Health Costs — And Voters Want to Hear From Biden and Republicans
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President Joe Biden is counting on outrage over abortion restrictions to help drive turnout for his reelection. Former President Donald Trump is promising to take another swing at repealing Obamacare.
But around America’s kitchen tables, those are hardly the only health topics voters want to hear about in the 2024 campaigns. A new KFF tracking poll shows that health care tops the list of basic expenses Americans worry about — more than gas, food, and rent. Nearly 3 in 4 adults — and majorities of both parties — say they’re concerned about paying for unexpected medical bills and other health costs.
“Absolutely health care is something on my mind,” Rob Werner, 64, of Concord, New Hampshire, said in an interview at a local coffee shop in January. He’s a Biden supporter and said he wants to make sure the Affordable Care Act, also known as Obamacare, is retained and that there’s more of an effort to control health care costs.
The presidential election is likely to turn on the simple question of whether Americans want Trump back in the White House. (Nikki Haley, the former South Carolina governor and U.S. ambassador to the United Nations, remained in the race for the Republican nomination ahead of Super Tuesday, though she had lost the first four primary contests.) And neither major party is basing their campaigns on health care promises.
But in the KFF poll, 80% of adults said they think it’s “very important” to hear presidential candidates talk about what they’d do to address health care costs — a subject congressional and state-level candidates can also expect to address.
“People are most concerned about out-of-pocket expenses for health care, and rightly so,” said Andrea Ducas, vice president of health policy at the Center for American Progress, a Washington, D.C.-based progressive think tank.
Here’s a look at the major health care issues that could help determine who wins in November.
Abortion
Less than two years after the Supreme Court overturned the constitutional right to an abortion, it is shaping up to be the biggest health issue in this election.
That was also the case in the 2022 midterm elections, when many voters rallied behind candidates who supported abortion rights and bolstered Democrats to an unexpectedly strong showing. Since the Supreme Court’s decision, voters in six states — including Kansas, Kentucky, and Ohio, where Republicans control the legislatures — have approved state constitutional amendments protecting abortion access.
Polls show that abortion is a key issue to some voters, said Robert Blendon, a public opinion researcher and professor emeritus at the Harvard T.H. Chan School of Public Health. He said up to 30% across the board see it as a “personal” issue, rather than policy — and most of those support abortion rights.
“That’s a lot of voters, if they show up and vote,” Blendon said.
Proposals to further protect — or restrict — abortion access could drive voter turnout. Advocates are working to put abortion-related measures on the ballot in such states as Arizona, Florida, Missouri, and South Dakota this November. A push in Washington toward a nationwide abortion policy could also draw more voters to the polls, Blendon said.
A surprise ruling by the Alabama Supreme Court in February that frozen embryos are children could also shake up the election. It’s an issue that divides even the anti-abortion community, with some who believe that a fertilized egg is a unique new person deserving of full legal rights and protections, and others believing that discarding unused embryos as part of the in vitro fertilization process is a morally acceptable way for couples to have children.
Pricey Prescriptions
Drug costs regularly rank high among voters’ concerns.
In the latest tracking poll, more than half — 55% — said they were very worried about being able to afford prescription drugs.
Biden has tried to address the price of drugs, though his efforts haven’t registered with many voters. While its name doesn’t suggest landmark health policy, the Inflation Reduction Act, or IRA, which the president signed in August 2022, included a provision allowing Medicare to negotiate prices for some of the most expensive drugs. It also capped total out-of-pocket spending for prescription drugs for all Medicare patients, while capping the price of insulin for those with diabetes at $35 a month — a limit some drugmakers have extended to patients with other kinds of insurance.
Drugmakers are fighting the Medicare price negotiation provision in court. Republicans have promised to repeal the IRA, arguing that forcing drugmakers to negotiate lower prices on drugs for Medicare beneficiaries would amount to price controls and stifle innovation. The party has offered no specific alternative, with the GOP-led House focused primarily on targeting pharmacy benefit managers, the arbitrators who control most Americans’ insurance coverage for medicines.
Costs of Coverage
Health care costs continue to rise for many Americans. The cost of employer-sponsored health plans have hit new highs in the past few months, raising costs for employers and workers alike. Experts have attributed the increase to high demand and expensive prices for certain drugs and treatments, notably weight loss drugs, as well as to medical inflation.
Meanwhile, the ACA is popular. The KFF poll found that more adults want to see the program expanded than scaled back. And a record 21.3 million people signed up for coverage in 2024, about 5 million of them new customers.
Enrollment in Republican-dominated states has grown fastest, with year-over-year increases of 80% in West Virginia, nearly 76% in Louisiana, and 62% in Ohio, according to the Centers for Medicare & Medicaid Services.
Public support for Obamacare and record enrollment in its coverage have made it politically perilous for Republicans to pursue the law’s repeal, especially without a robust alternative. That hasn’t stopped Trump from raising that prospect on the campaign trail, though it’s hard to find any other Republican candidate willing to step out on the same limb.
“The more he talks about it, the more other candidates have to start answering for it,” said Jarrett Lewis, a partner at Public Opinion Strategies, a GOP polling firm.
“Will a conversation about repeal-and-replace resonate with suburban women in Maricopa County?” he said, referring to the populous county in Arizona known for being a political bellwether. “I would steer clear of that if I was a candidate.”
Biden and his campaign have pounced on Trump’s talk of repeal. The president has said he wants to make permanent the enhanced premium subsidies he signed into law during the pandemic that are credited with helping to increase enrollment.
Republican advisers generally recommend that their candidates promote “a market-based system that has the consumer much more engaged,” said Lewis, citing short-term insurance plans as an example. “In the minds of Republicans, there is a pool of people that this would benefit. It may not be beneficial for everyone, but attractive to some.”
Biden and his allies have criticized short-term insurance plans — which Trump made more widely available — as “junk insurance” that doesn’t cover care for serious conditions or illnesses.
Entitlements Are Off-Limits
Both Medicaid and Medicare, the government health insurance programs that cover tens of millions of low-income, disabled, and older people, remain broadly popular with voters, said the Democratic pollster Celinda Lake. That makes it unlikely either party would pursue a platform that includes outright cuts to entitlements. But accusing an opponent of wanting to slash Medicare is a common, and often effective, campaign move.
Although Trump has said he wouldn’t cut Medicare spending, Democrats will likely seek to associate him with other Republicans who support constraining the program’s costs. Polls show that most voters oppose reducing any Medicare benefits, including by raising Medicare’s eligibility age from 65. However, raising taxes on people making more than $400,000 a year to shore up Medicare’s finances is one idea that won strong backing in a recent poll by The Associated Press and NORC Center for Public Affairs Research.
Brian Blase, a former Trump health adviser and the president of Paragon Health Institute, said Republicans, if they win more control of the federal government, should seek to lower spending on Medicare Advantage — through which commercial insurers provide benefits — to build on the program’s efficiencies and ensure it costs taxpayers less than the traditional program.
So far, though, Republicans, including Trump, have expressed little interest in such a plan. Some of them are clear-eyed about the perils of running on changing Medicare, which cost $829 billion in 2021 and is projected to consume nearly 18% of the federal budget by 2032.
“It’s difficult to have a frank conversation with voters about the future of the Medicare program,” said Lewis, the GOP pollster. “More often than not, it backfires. That conversation will have to happen right after a major election.”
Addiction Crisis
Many Americans have been touched by the growing opioid epidemic, which killed more than 112,000 people in the United States in 2023 — more than gun deaths and road fatalities combined. Rural residents and white adults are among the hardest hit.
Federal health officials have cited drug overdose deaths as a primary cause of the recent drop in U.S. life expectancy.
Republicans cast addiction as largely a criminal matter, associating it closely with the migration crisis at the U.S. southern border that they blame on Biden. Democrats have sought more funding for treatment and prevention of substance use disorders.
“This affects the family, the neighborhood,” said Blendon, the public opinion researcher.
Billions of dollars have begun to flow to states and local governments from legal settlements with opioid manufacturers and retailers, raising questions about how to best spend that money. But it isn’t clear that the crisis, outside the context of immigration, will emerge as a campaign issue.
KFF Health News is a national newsroom that produces in-depth journalism about health issues and is one of the core operating programs at KFF—an independent source of health policy research, polling, and journalism. Learn more about KFF.
Subscribe to KFF Health News’ free Morning Briefing.
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Treating Knee Arthritis Without Surgery
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There are a lot of possible ways, and some have rather more evidence than others:
Here’s what works
Let’s start at the top:
- Exercise and physiotherapy: the strongest evidence overall, as strengthening your muscles around the knee reduces pain and improves function more reliably than any medication.
- In the category of exercise, it’s important to keep moving but avoid or adjust activities that significantly worsen your knee pain to reduce joint stress.
- Weight loss: one of the most powerful interventions if applicable, with even modest loss significantly reducing joint load and pain, especially when using stairs, where forces are greatly increased.
- NSAIDs (over-the-counter or prescription): among the most effective medications for arthritic pain relief, but limited by side effects with long-term use.
- Injections (corticosteroids): effective for short-term relief during flare-ups, though benefits typically fade over weeks to a few months.
- Braces and orthotics: moderately effective, especially if your arthritis affects a specific compartment of your knee.
- Topical treatments: creams or gels (anti-inflammatories, anesthetics, or CBD) for localized relief with fewer systemic effects, though generally less powerful than oral medications.
- Diet changes: supportive rather than primary treatment, but can help reduce inflammation and contribute to weight loss.
- Acetaminophen: safer for the kidneys, but less effective than NSAIDs for most people with knee arthritis, as well as being hepatotoxic (poisons your liver) if overused.
- Hyaluronic acid injections: mixed evidence, with some people benefiting but overall effects being modest and inconsistent.
Some other things discussed that don’t fit well into a ranking from best to worst:
- They made the strange choice to lump “magnets, copper, or red light therapy” together as one item having “weak evidence though placebo might help”, when one of those 3 things is not like the others!
- Red light therapy is very well-evidenced for helping a good number of health things; it’s simply that arthritis isn’t one of them, and it’s a bit strange that they even brought it up, as it’s not a health claim we’ve seen made for it in the wild. It would be like taking time in the video to say that soap won’t help against arthritis—it’s technically a true statement, but why mention it at all?
- They did a similar thing with supplements, saying “benefits vary and evidence is mixed”, but it rather makes a difference which supplement! So, in the “learn more” section below, we’ve linked an article that talks about 5 supplements that do have good evidence vs arthritis.
For the video itself meanwhile, enjoy:
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Want to learn more?
You might also like:
Five Supplements That Actually Work Vs Arthritis
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- Exercise and physiotherapy: the strongest evidence overall, as strengthening your muscles around the knee reduces pain and improves function more reliably than any medication.
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What is grounding and could it improve my sleep? Here’s the science behind this TikTok trend
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Have you ever felt an unexpected sense of calm while walking barefoot on grass? Or noticed your stress begin to fade as you stood ankle deep in the ocean? If so, you may have unknowingly “grounded” yourself to the earth.
Grounding, also known as earthing, is the practice of making direct physical contact with the Earth’s surface. Our ancestors embraced this trend without knowing it. But with the invention of indoor homes, footpaths, roads, and even shoes, we have become less physically connected with the earth.
Grounding has been suggested to have a number of benefits, such as improving mood, and reducing stress and pain. But overall, there’s limited conclusive evidence on the benefits of grounding.
Somewhat ironically, the concept of grounding in 2025 is heavily influenced by technology, rather than getting out into nature. Consumers are being hit with social media reels promoting a range of technologies that ground us, and improve our health.
Among the most common are promises of improved sleep with the use of a grounding sheet or mat. But is this just another TikTok trend, or could these products really help us get a better night’s sleep?
Alexey Demidov/Pexels Bringing the outdoors in
The human body is conductive, which means it can exchange electricity with Earth and artificial sources, such as electronic devices or objects. (Sometimes, this exchange can result in an electric or static shock.)
Proponents of grounding claim the practice reconnects “the conductive human body to the Earth’s natural and subtle surface electric charge”.
They credit this process with physiological and psychological benefits (but again, the evidence is limited).
Grounding technologies can vary in type (for example, under-desk foot mats, mattress toppers and bed sheets) but all are designed to provide a path for electric charges to flow between your body and the earth.
The bottom prong you see in your three-prong wall socket is a “ground” or “earth” terminal. It provides a direct connection to earth via your building’s wiring, diverting excess or unsafe voltage into the ground. This protects you and your devices from potential electrical faults.
Grounding technology uses this terminal as a pathway for the proposed electrical exchange between you and earth, while in the comfort of your home.
Could grounding improve your sleep?
The research in this area is still emerging.
A 2025 study from Korea recruited 60 participants, gave half of them a grounding mat, and gave the other half a visually identical mat that didn’t have grounding technology. The researchers used a “double-blind” protocol, meaning neither the participants nor the researchers knew which participants were given grounding mats.
All participants wore sleep trackers and were asked to use their mat (that is, sit or lie on it) for six hours per day. The researchers found that after 31 days, participants in the grounding mat group slept longer on average (as measured by their sleep trackers) than those in the control group.
The researchers also used questionnaires to collect measures of insomnia, sleep quality, daytime sleepiness, and stress. After 31 days, participants in both groups improved on all measures.
There were no differences between the grounded and ungrounded groups for sleep quality, daytime sleepiness, and stress. And while grounded participants showed significantly lower insomnia severity after the intervention, this difference was also present at the start of the study. So it’s unclear if grounding had a tangible impact on sleep.
Could grounding technologies really help you sleep better? Andrea Piacquadio/Pexels In another double-blind study, published in 2022, researchers in Taiwan examined the effectiveness of using grounding mats to improve sleep among patients with Alzheimer’s disease. The findings indicated that spending 30 minutes on a grounding mat five times per week resulted in improved sleep quality.
While previous research has suggested using grounding technologies may lead to improvements in mood, no differences were seen in measures of anxiety and depression in this study.
Grounding for gains?
Grounding technology has also been touted as having other benefits, such as reducing pain and inflammation.
A 2019 study found participants who slept on a grounding mat after intense exercise felt less sore and showed lower levels of inflammation in their blood compared to those who were ungrounded.
Grounding after a workout may help you feel better and recover faster, but it’s still unclear whether and how grounding affects long-term training results or fitness gains.
There’s some evidence grounding could help with exercise recovery. Monster Ztudio/Shutterstock Add to cart?
So should you cash in on your favourite influencer’s discount code and grab a grounding mat? At the risk of spouting a common cliche of cautious scientists, our answer is that we don’t know yet.
What we do know is the existing research, albeit emerging, has shown no evidence grounding technology can negatively affect your sleep or recovery after exercise. So if you love your grounding mat or grounding sheet, or want to see if grounding works for you, feel free to give it a go.
Keep in mind, grounding products can retail for anywhere from around A$30 to $300 or more.
On the other hand, grounding on the grass in the great outdoors is free. While there’s limited evidence that grounding outdoors can improve sleep, spending time in outdoor light may itself benefit sleep, regulate circadian rhythms, and improve mood.
Finally, while grounding could be an interesting strategy to try, if you’re experiencing ongoing problems with your sleep, or suspect you may have a sleep disorder, the first step should be reaching out to a medical professional, such as your GP.
Dean J. Miller, Senior Lecturer, Appleton Institute, HealthWise Research Group, CQUniversity Australia and Charlotte Gupta, Senior Postdoctoral Research Fellow, Appleton Institute, HealthWise Research Group, CQUniversity Australia
This article is republished from The Conversation under a Creative Commons license. Read the original article.
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When Did You Last Have a Cognitive Health Check-Up?
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When Did You Last Have a Cognitive Health Check-Up?
Regular health check-ups are an important part of a good health regime, especially as we get older. But after you’ve been prodded, probed, sampled and so forth… When did you last have a cognitive health check-up?
Keeping on top of things
In our recent Monday Research Review main feature about citicoline, we noted that it has beneficial effects for a lot of measures of cognitive health.
And that brought us to realize: just how on top of this are we?
Your writer here today could tell you what her sleep was like on any night in the past year, what her heart rate was like, her weight, and all that. Moods too! There’s an app for that. But cognitive health? My last IQ test was in 2001, and I forget when my last memory test was.
It’s important to know how we’re doing, or else how to we know if there has been some decline? We’ve talked previously about the benefits of brain-training of various kinds to improve cognition, so in some parts we’ll draw on the same resources today, but this time the focus is on getting quick measurements that we can retest regularly (mark the calendar!)
Some quick-fire tests
These tests are all free, quick, and accessible. Some of them will try to upsell you on other (i.e. paid) services; we leave that to your own discretion, but the things we’ll be using today are free.
Test your verbal memory
This one’s a random word list generator. It defaults to 12 words, but you can change that if you like. Memorize the words, and then test yourself by seeing how many you can write down from memory. If it gets too easy, crank up the numbers.
Test your visual memory
This one’s a series of images; the test is to click to say whether you’ve seen this exact image previously in the series or not.
Test your IQ
This one’s intended to be general purpose intelligence; in reality, IQ tests have their flaws too, but it’s not a bad metric to keep track of. Just don’t get too hung up on the outcome, and remember, your only competition is yourself!
Test your attention / focus
This writer opened this and this three other attention tests (to get you the best one) before getting distracted, noting the irony, and finally taking the test. Hopefully you can do better!
Test your creativity
This one’s a random object generator. Give yourself a set period of time (per your preference, but make a note of the time you allow yourself, so that you can use the same time period when you retest yourself at a later date) in which to list as many different possible uses for the item.
Test your musical sense
This one’s a pitch recognition test. So, with the caveat that it is partially testing your hearing as well as your cognition, it’s a good one to take and regularly retest in any case.
How often should you retest?
There’s not really any “should” here, but to offer some advice:
- If you take them too often, you might find you get bored of doing so and stop, essentially burning out.
- If you don’t take them regularly, you may forget, lose this list of tests, etc.
- Likely a good “sweet spot” is quarterly or six-monthly, but there’s nothing wrong with testing annually either.
It’s all about the big picture, after all.
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Biggest Collagen Study Yet Shows What It Does (& Doesn’t) Improve
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On May the 4th (International Star Wars Day), we joked:
May The Fourth Be With You ✨
If you’re trying to remember what that mystical web-like thing is that surrounds us, fills us, and binds us together… It’s collagen! So, to help your body make more collagen, make sure to get plenty of protein, vitamins C & D, and also copper and zinc!
Read the science: We Are Such Stuff As Fish Are Made Of…and we were also telling the truth, because as collagen really is…
The stuff that holds us together
The name literally means “makes sticky” (coll— = to stick, —gen = to make), and that’s exactly what it does. It’s necessary for many “body bits”, including bones, joints, skin, and more.
But there are a lot of conflicting claims about what it will and won’t do as a supplement. We’ve talked about this before, doing some mythbusting such as:
Are Collagen Molecules Too Big To Be Absorbed? ← the short version is: 1) through the skin? Definitely 2) through the gut? Yes, unless you take them apart first, in a way the body can reassemble later
This latter thing (taking the collagen molecules apart first, in a way the body can reassemble later) is what is going on in the case of collagen peptides.
However, even they aren’t a panacea.
Researchers (Dr. Julia Gawronska et al.) did the biggest research review of this topic yet, and analyzed 16 systematic reviews, 113 randomized controlled trials, and 7,983 participants to assess collagen supplementation across multiple health outcomes.
The review itself is interesting, and/but we know you’ll be most interested in the answers it arrived at, so we’ll skip straight to those:
- Skin and joint benefits: collagen supplementation showed consistent improvements in skin elasticity and hydration, and it reduced osteoarthritis-related pain and stiffness, with stronger effects seen when taken over longer periods.
- Most of these studies started at 5g/day, by the way, though doses up to 20g/day are also very common. More than 30g/day is unlikely to give meaningful additional benefits, unless your diet is very low in protein (in which case, because collagen is made of proteins, yes, the extra will be beneficial, but only because of the dietary shortfall for which you are in that case compensating)
- Musculoskeletal effects beyond the above: collagen was linked to modest improvements in muscle mass, muscle structure, and tendon structure, suggesting limited but plausible support for aspects of healthy aging.
- This is likely a combination of the same effects as the above, and also that once again yes, collagen taken as a supplement is supplementing dietary protein, so if your diet was low in that, getting more will help—hence the “modest improvements” on the population level, since the numbers are population averages.
- Sports performance, for some reason: the review found little evidence that collagen improves exercise performance, post-workout recovery, muscle soreness, or tendon mechanical function.
- We’re unsure as to why why anyone thought that collagen would improve those things, but we acknowledge that it’s good in science to not leave assumptions untested, so it’s as well that the science was done, even if the results were not exciting and just confirmed what a reasonable person might already have expected.
- Other health outcomes: results for cardiometabolic health and oral health were mixed or inconclusive, with no strong evidence for major benefits in cholesterol, blood pressure, blood sugar, or dental outcomes.
You can read the paper in full, here: Collagen Supplementation for Skin and Musculoskeletal Health: An Umbrella Review of Meta-Analyses on Elasticity, Hydration, and Structural Outcomes
Prefer to do things as naturally as possible, and/or perhaps you are vegetarian/vegan?
Check out: The Best Foods For Collagen Production
Want to learn more?
For a much more in-depth understanding of the pharmacokinetics of collagen, you might like this book we reviewed:
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- Skin and joint benefits: collagen supplementation showed consistent improvements in skin elasticity and hydration, and it reduced osteoarthritis-related pain and stiffness, with stronger effects seen when taken over longer periods.
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The Alzheimer’s Gene That Varies By Race & Sex
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The Alzheimer’s Gene That Varies By Race & Sex
You probably know that there are important genetic factors that increase or decrease Alzheimer’s Risk. If you’d like a quick refresher before we carry on, here are two previous articles on this topic:
- Genetic Testing: Health Benefits & Methods (about personal genomics and health, including Alzheimer’s)
- The Surprising Link Between Type 2 Diabetes & Alzheimer’s (about the APOE-ε4 allele that is implicated in both)
A Tale of Two Alleles
It has generally been understood that APOE-ε2 lowers Alzheimer’s disease risk, and APOE-ε4 increases it.
However, for reasons beyond the scope of this article, research populations for genetic testing are overwhelmingly white. If you, dear reader, are white, you may be thinking “well, I’m white, so this isn’t a problem for me”, you might still want to read on…
An extensive new study, published days ago, by Dr. Belloy et al., looked at how these correlations held out per race and sex. They found:
- The “APOE-ε2 lowers; APOE-ε4 increases” dictum held out strongest for white people.
- In the case of Hispanic people, there was only a small correlation on the APOE-ε4 side of things, and none on the APOE-ε2 side of things per se.
- East Asians also saw no correlation with regard to APOE-ε2 per se.
- But! Hispanic and East Asian people had a reduced risk of Alzheimer’s if and only if they had both APOE-ε2 and APOE-ε4.
- Black people, meanwhile, saw a slight correlation with regard to the protective effect of APOE-ε2, and as for APOE-ε4, if they had any European ancestry, increased European ancestry meant a higher increased risk factor if they had APOE-ε4. African ancestry, on the other hand, had a protective effect, proportional to the overall amount of that ancestry.
And as for sex…
- Specifically for white people with the APOE-ε3/ε4 genotype, especially in the age range of 60–70, the genetic risk for Alzheimer’s was highest in women.
If you’d like to read more and examine the data for yourself:
APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry
Want to reduce your Alzheimer’s risk?
We have just the thing for you:
How To Reduce Your Alzheimer’s Risk: It’s Never Too Early To Do These 11 Things
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