What Does Kaempferol Do, Anyway?
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It’s Q&A Day at 10almonds!
Have a question or a request? We love to hear from you!
In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!
As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!
So, no question/request too big or small 😎
❝In the this or that article, you said kampeferol was a famously good flavonol on a par with quercetin, does it do the same thing or does it do something different, and is it worth supplementing?❞
So, this will be in reference to a This-or-That from last week:
Cantaloupe vs Cucumber – Which is Healthier?
Let’s break down your question into parts:
- Is it comparable to quercetin?
- Does it have special properties of its own?
- Is it worth supplementing?
Is it comparable to quercetin?
They are both flavonols, and potent ones at that. Similarities include that they’re found in many of the same plants, and that (like most if not all polyphenols) they have antioxidant and anti-inflammatory benefits, which in turn usually translate to anti-aging and anticancer benefits too.
You can read more about quercetin here: Fight Inflammation & Protect Your Brain, With Quercetin
You can read more about polyphenols in general here: 21 Most Beneficial Polyphenols & What Foods Have Them ← quercetin and kaempferol are #1 and #2 on this list, respectively
Does it have special properties of its own?
Yes it does!
❝Epidemiological studies have shown an inverse relationship between kaempferol intake and cancer.
Kaempferol may help by augmenting the body’s antioxidant defense against free radicals, which promote the development of cancer.
At the molecular level, kaempferol has been reported to modulate a number of key elements in cellular signal transduction pathways linked to apoptosis, angiogenesis, inflammation, and metastasis.
Significantly, kaempferol inhibits cancer cell growth and angiognesis and induces cancer cell apoptosis, but on the other hand, kaempferol appears to preserve normal cell viability, in some cases exerting a protective effect.❞
Read in full: A review of the dietary flavonoid, kaempferol on human health and cancer chemoprevention
It is also particularly good for the gut:
❝Most recently, an increasing number of studies have demonstrated the significance of kaempferol in the regulation of intestinal function and the mitigation of intestinal inflammation❞
Read in full: A Critical Review of Kaempferol in Intestinal Health and Diseases
This also means it is particularly efficacious against food allergies:
❝we screened food ingredients with the expectation of finding dietary compounds that exert beneficial effects on intestinal immune tolerance and identified kaempferol, a flavonoid, as the compound that most effectively increased Aldh1a2 mRNA levels❞
(that’s good)
That one’s a bit scientifically denser than we usually try to find when citing sources here, so here’s a pop-science article about the same thing, which explains in more words than we have room to here:
Flavonoid kaempferol could offer natural relief for food allergies ← much lighter reading, but still very informative
Kaempferol (like quercetin, granted) is also a potent neuroprotective agent, not least of all because its anti-inflammatory powers extend to reducing neuroinflammation (not everything does, because not everything we ingest can pass the blood-brain barrier to affect what goes on in the brain):
…and more:
❝it may be used to treat numerous acute and chronic inflammation-induced diseases, including intervertebral disc degeneration and colitis, as well as post-menopausal bone loss and acute lung injury. In addition, it has beneficial effects against cancer, liver injury, obesity and diabetes, inhibits vascular endothelial inflammation, protects the cranial nerve and heart function, and may be used for treating fibroproliferative disorders, including hypertrophic scar.❞
Read in full: Recent progress regarding kaempferol for the treatment of various diseases
Is it worth supplementing?
If you eat a lot of leafy greens, cruciferous vegetables, and/or citrus fruits, and/or drink tea (true teas from tea plants, not miscellaneous herbal infusions), then you probably get a good dose of kaempferol already.
However, if you want to supplement, hawthorn berry is not a bad one to go with, like this example product on Amazon 😎
We wrote about this before, here: Hawthorn For The Heart (& More)
As for teas, if you’re wondering about the merits of black, white, green or red, check out:
Black, White, Green, Red: Which Kind Of Tea Is Best For The Health, According To Science? ← this covers many factors
Enjoy!
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Anti-Inflammatory Diet 101 (What to Eat to Fight Inflammation)
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Chronic inflammation is a cause and/or exacerbating factor in very many diseases. Arthritis, diabetes, and heart disease are probably top of the list, but there are lots more where they came from. And, it’s good to avoid those things. So, how to eat to avoid inflammation?
Let food be thy medicine
The key things to keep in mind, the “guiding principles” are to prioritize whole, minimally-processed foods, and enjoy foods with plenty of antioxidants. Getting a healthy balance of omega fatty acids is also important, which for most people means getting more omega-3 and less omega-6.
Shopping list (foods to prioritize) includes:
- fruits and vegetables in a variety of colors (e.g. berries, leafy greens, beats)
- whole grains, going for the most fiber-rich options (e.g. quinoa, brown rice, oats)
- healthy fats (e.g. avocados, nuts, seeds)
- fatty fish (e.g. salmon, mackerel, sardines) ← don’t worry about this if you’re vegetarian/vegan though, as the previous category can already cover it
- herbs and spices (e.g. turmeric, garlic, ginger)
Noping list (foods to avoid) includes:
- refined carbohydrates
- highly processed and/or fried foods
- red meats and/or processed meats (yes, that does mean that organic grass-fed farmers’ pinky-promise-certified holistically-raised beef is also off the menu)
- dairy products, especially if unfermented
For more information on each of these, plus advice on transitioning away from an inflammatory diet, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like to read:
How to Prevent (or Reduce) Inflammation
Take care!
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Spinach vs Vine Leaves – Which is Healthier?
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Our Verdict
When comparing spinach to vine leaves, we picked the vine leaves.
Why?
Granted, they’re not available in most supermarkets, but if you live not too far from a wine-growing region, then they’ll be available at markets, and certainly stuffed vine leaves are thing found in many restaurants (though those are usually saltier than you’d make them at home—restaurants make most of their money from selling you drinks, after all, not the food). So, it’s worth noting the simple nutritional values if you prepare your own food:
In terms of macros, the most relevant difference is that vine leaves have about 5x the fiber. They’re also higher in carbs, but the overall glycemic index is lower in any case, so that’s not an issue. An easy win for vine leaves here.
Looking at vitamins, spinach has more of vitamins B1, B9, K, and choline, while vine leaves have more of vitamins A, B2, B3, B5, B6, B7, and C. Another win for vine leaves.
When it comes to minerals, spinach has more iron, potassium, and selenium, while vine leaves have more calcium, copper, magnesium, manganese, and phosphorus. One more win for vine leaves.
In terms of phytochemicals, spinach has a much higher oxalate content (that’s not a problem for most people, but bad if you have certain kidney issues).
Adding up the sections, it’s a clear overall win for vine leaves; by all means enjoy either or both though, unless you have kidney problems, of course!
Want to learn more?
You might like:
What’s Your Plant Diversity Score?
Enjoy!
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Instant Quiz Results, No Email Needed
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❓ Q&A With 10almonds Subscribers!
Q: I like that the quizzes (I’ve done two so far) give immediate results , with no “give us your email to get your results”. Thanks!
A: You’re welcome! That’s one of the factors that influences what things we include here! Our mission statement is “to make health and productivity crazy simple”, and the unwritten part of that is making sure to save your time and energy wherever we reasonably can!
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Uric Acid’s Extensive Health Impact (And How To Lower It)
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Uric Acid’s Extensive Health Impact (And How To Lower It)
This is Dr. David Perlmutter. He’s a medical doctor, and a Fellow of the American College of Nutrition. He’s a member of the Editorial Board for the Journal of Alzheimer’s Disease, and has been widely published in many other peer-reviewed journals.
What does he want us to know?
He wants us to know about the health risks of uric acid (not something popularly talked about so much!), and how to reduce it.
First: what is it? Uric acid is a substance we make in our own body. However, unlike most substances we make in our body, we have negligible use for it—it’s largely a waste product, usually excreted in urine.
However, if we get too much, it can build up (and crystallize), becoming such things as kidney stones, or causing painful inflammation if it shows up in the joints, as in gout.
More seriously (unpleasant as kidney stones and gout may be), this inflammation can have a knock-on effect triggering (or worsening) other inflammatory conditions, ranging from non-alcoholic fatty liver disease, to arthritis, to dementia, and even heart problems. See for example:
- David Perlmutter | Uric Acid and Cognitive Decline
- American Heart Association | Uric acid linked to later risk for irregular heart rhythm
- World Journal of Gastroenterology | The role of uric acid in non-alcoholic steatohepatitis development
How can we reduce our uric acid levels?
Uric acid is produced when we metabolize purine nucleotides, which are found in many kinds of food. We can therefore reduce our uric acid levels by reducing our purine intake, as well as things that mess up our liver’s ability to detoxify things. Offsetting the values for confounding variables (such as fiber content, or phytochemicals that mitigate the harm), the worst offenders include…
Liver-debilitating things:
- Alcohol (especially beer)
- High-fructose corn syrup (and other fructose-containing things that aren’t actual fruit)
- Other refined sugars
- Wheat / white flour products (this is why beer is worse than wine, for example; it’s a double-vector hit)
Purine-rich things:
- Red meats and game
- Organ meats
- Oily fish, and seafood (great for some things; not great for this)
Some beans and legumes are also high in purines, but much like real fruit has a neutral or positive effect on blood sugar health despite its fructose content, the beans and legumes that are high in purines, also contain phytochemicals that help lower uric acid levels, so have a beneficial effect.
Eggs (consumed in moderation) and tart cherries have a uric-acid lowering effect.
Water is important for all aspects of health, and doubly important for this.
Hydrate well!
Lifestyle matters beyond diet
The main key here is metabolic health, so Dr. Perlmutter advises the uncontroversial lifestyle choices of moderate exercise and good sleep, as well as (more critically) intermittent fasting. We wrote previously on other things that can benefit liver health:
…in this case, that means the liver gets a break to recuperate (something it’s very good at, but does need to get a chance to do), which means that while you’re not giving it something new to do, it can quickly catch up on any backlog, and then tackle any new things fresh, next time you start eating.
Want to know more about this from Dr. Perlmutter?
You might like his article:
An Integrated Plan for Lowering Uric Acid ← more than we had room for here; he also talks about extra things to include in your diet/supplementation regime for beneficial effects!
And/or his book:
…on which much of today’s main feature was based.
Take care!
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If You’re Not Flexible, These Are The Only 3 Stretches You Need, To Fix That
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If you can’t put your leg behind your head while standing, try doing the splits against a wall first, and progress from there! ← text version of an item from a “if you can’t do this yet, try this first” picture set this writer saw on Instagram once upon a time
So, what if you’re more at the point of not quite being able to touch your toes yet?
From zero to…
Liv, of LivInLeggings fame, has these three starter-stretches that are actually starter-stretches:
Stretch 1: Reverse Tabletop with Foot Tuck Variation
- Sit on the floor, feet slightly wider than your hips, lean back onto your hands (fingertips pointing outward).
- Lift your hips towards a reverse tabletop, engage your glutes, and flatten the front of your hips.
- Add a foot tuck variation by stepping one foot back and pressing your weight forward.
Benefits:
- Stretches multiple muscles, including the soles of the feet.
- Improves foot arches, balance, and stability.
- Loosens fascia, enhancing flexibility in subsequent stretches.
Stretch 2: Squat to Forward Fold
- Start in a low squat (feet wider than your hips, toes mostly forward).
- Alternate between a low squat and a forward fold, keeping your hands on the floor or your toes.
Benefits:
- Stretches hamstrings, glutes, and lower back.
- Maintains good form and avoids overstraining.
Stretch 3: Side Lunge with Side Body Reach
- Begin in a tall kneeling position, step one foot out to the side (toes pointing outward).
- Lunge your hips towards your front ankle, keeping your tailbone tucked.
- Add a side body reach by resting your forearm on your thigh and reaching the other arm overhead.
- For a deeper stretch, cradle the back of your head with your hand, pressing lightly for a tricep stretch.
Benefits:
- Stretches inner thighs, lats, and triceps.
- Improves posture, shoulder mobility, and low squat ability.
For more on each of these plus visual demonstrations, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like to read:
Test For Whether You Will Be Able To Achieve The Splits
Take care!
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Entertaining Harissa Traybake
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No, it’s not entertaining in the sense that it will tell you jokes or perhaps dance for you, but rather: it can be easily prepared in advance, kept in the fridge for up to 3 days, and reheated when needed as part of a spread when entertaining, leaving you more time to spend with your houseguests.
Aside from its convenience, it is of course nutritious and delicious:
You will need
- 14 oz cherry tomatoes
- 2 cans chickpeas, drained and rinsed (or 2 cups cooked chickpeas, drained and rinsed)
- 2 eggplants, cut into ¾” cubes
- 1 red onion, roughly chopped
- 1 bulb garlic
- 2 tbsp extra virgin olive oil
- 1 tbsp harissa paste
- 1 tbsp ras el-hanout
- 1 tsp MSG or 2 tsp low-sodium salt
Method
(we suggest you read everything at least once before doing anything)
1) Preheat the oven to 400℉ / 200℃
2) Mix the onion, eggplant, and garlic (whole cloves; just peel them and put them in) with the olive oil in a mixing bowl, ensuring everything is coated evenly.
3) Add in 1 tbsp of the harissa paste, 1 tbsp of the ras-el hanout, and half of the MSG/salt, and again mix thoroughly to coat evenly.
4) Bake in the oven, in a walled tray, for about 30 minutes, giving things a stir/jiggle halfway through to ensure they cook evenly.
5) Add the cherry tomatoes to the tray, and return to the oven for another 10 minutes.
6) Mix the chickpeas with the other 1 tbsp of the harissa paste, the other 1 tbsp of the ras-el hanout, and the other half of the MSG/salt, and add to the tray, returning it to the oven for a final 10 minutes.
7) Serve hot, or set aside for later, refrigerating once cool enough to do so. When you do serve, we recommend serving with a yogurt, cucumber, and mint dip, and perhaps flatbreads (you can use our Healthy Homemade Flatbreads recipe):
Enjoy!
Want to learn more?
For those interested in some of the science of what we have going on today:
- Eat More (Of This) For Lower Blood Pressure
- Lycopene’s Benefits For The Gut, Heart, Brain, & More
- Our Top 5 Spices: How Much Is Enough For Benefits?
Take care!
Don’t Forget…
Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!
Learn to Age Gracefully
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