Lycopene’s Benefits For The Gut, Heart, Brain, & More

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What Doesn’t Lycopene Do?

Lycopene is an antioxidant carotenoid famously found in tomatoes; it actually appears in even higher levels in watermelon, though. If you are going to get it from tomato, know that cooking improves the lycopene content rather than removing it (watermelon, on the other hand, can be enjoyed as-is and already has the higher lycopene content).

Antioxidant properties

Let’s reiterate the obvious first, for the sake of being methodical and adding a source. Lycopene is a potent antioxidant with multiple health benefits:

Lycopene: A Potent Antioxidant with Multiple Health Benefits

…and as such, it does all the things you might reasonably expect and antioxidant to do. For example…

Anti-inflammatory properties

In particular, it regulates macrophage activity, reducing inflammation while improving immune response:

Lycopene Regulates Macrophage Immune Response through the Autophagy Pathway Mediated by RIPK1

As can be expected of most antioxidants and anti-inflammatory agents, it also has…

Anticancer properties

Scientific papers tend to be “per cancer type”, so we’re just going to give one example, but there’s pretty much evidence for its utility against most if not all types of cancer. We’re picking prostate cancer though, as it’s one that’s been studied the most in the context of lycopene intake—in this study, for example, it was found that men who enjoyed at least two servings of lycopene-rich tomato sauce per week were 30% less likely to develop prostate cancer than those who didn’t:

Dietary lycopene intake and risk of prostate cancer defined by ERG protein expression

If you’d like to see something more general, however, then check out:

Potential Use of Tomato Peel, a Rich Source of Lycopene, for Cancer Treatment

It also fights Candida albicans

Ok, this is not (usually) so life-and-death as cancer, but reducing our C. albicans content (specifically: in our gut) has a lot of knock-on effects for other aspects of our health, so this isn’t one to overlook:

Lycopene induces apoptosis in Candida albicans through reactive oxygen species production and mitochondrial dysfunction

The title does not make this clear, but yes: this does mean it has an antifungal effect. We mention this because often cellular apoptosis is good for an overall organism, but in this case, it simply kills the Candida.

It’s good for the heart

A lot of studies focus just on triglyceride markers (which lycopene improves), but more tellingly, here’s a 10-year observational study in which diets rich in lycopene were associated to a 17–26% lower risk of heart disease:

Relationship of lycopene intake and consumption of tomato products to incident CVD

…and a 39% overall reduced mortality in, well, we’ll let the study title tell it:

Higher levels of serum lycopene are associated with reduced mortality in individuals with metabolic syndrome

…which means also:

It’s good for the brain

As a general rule of thumb, what’s good for the heart is good for the brain (because the brain needs healthy blood flow to stay healthy, and is especially vulnerable when it doesn’t get that), and in this case that rule of thumb is also borne out by the post hoc evidence, specifically yielding a 31% decreased incidence of stroke:

Dietary and circulating lycopene and stroke risk: a meta-analysis of prospective studies

Is it safe?

As a common food product, it is considered very safe.

If you drink nothing but tomato juice all day for a long time, your skin will take on a reddish hue, which will go away if you stop getting all your daily water intake in tomato juice.

In all likelihood, even if you went to extremes, you would get sick from the excess of vitamin A (generally present in the same foods) sooner than you’d get sick from the excess of lycopene.

Want to try some?

We don’t sell it, and also we recommend simply enjoying tomatoes, watermelons, etc, but if you do want a supplement, here’s an example product on Amazon

Enjoy!

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  • How light tells you when to sleep, focus and poo

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    This is the next article in our ‘Light and health’ series, where we look at how light affects our physical and mental health in sometimes surprising ways. Read other articles in the series.

    Exposure to light is crucial for our physical and mental health, as this and future articles in the series will show.

    But the timing of that light exposure is also crucial. This tells our body to wake up in the morning, when to poo and the time of day to best focus or be alert. When we’re exposed to light also controls our body temperature, blood pressure and even chemical reactions in our body.

    But how does our body know when it’s time to do all this? And what’s light got to do with it?

    nymphoenix/Shutterstock

    What is the body clock, actually?

    One of the key roles of light is to re-set our body clock, also known as the circadian clock. This works like an internal oscillator, similar to an actual clock, ticking away as you read this article.

    But rather than ticking you can hear, the body clock is a network of genes and proteins that regulate each other. This network sends signals to organs via hormones and the nervous system. These complex loops of interactions and communications have a rhythm of about 24 hours.

    In fact, we don’t have one clock, we have trillions of body clocks throughout the body. The central clock is in the hypothalamus region of the brain, and each cell in every organ has its own. These clocks work in concert to help us adapt to the daily cycle of light and dark, aligning our body’s functions with the time of day.

    However, our body clock is not precise and works to a rhythm of about 24 hours (24 hours 30 minutes on average). So every morning, the central clock needs to be reset, signalling the start of a new day. This is why light is so important.

    The central clock is directly connected to light-sensing cells in our retinas (the back of the eye). This daily re-setting of the body clock with morning light is essential for ensuring our body works well, in sync with our environment.

    In parallel, when we eat food also plays a role in re-setting the body clock, but this time the clock in organs other than the brain, such as the liver, kidneys or the gut.

    So it’s easy to see how our daily routines are closely linked with our body clocks. And in turn, our body clocks shape how our body works at set times of the day.

    What time of day?

    Matt Garrow/The Conversation. Adapted from Delos, CC BY

    Let’s take a closer look at sleep

    The naturally occurring brain hormone melatonin is linked to our central clock and makes us feel sleepy at certain times of day. When it’s light, our body stops making melatonin (its production is inhibited) and we are alert. Closer to bedtime, the hormone is made, then secreted, making us feel drowsy.

    Our sleep is also partly controlled by our genes, which are part of our central clock. These genes influence our chronotype – whether we are a “lark” (early riser), “night owl” (late sleeper) or a “dove” (somewhere in between).

    But exposure to light at night when we are supposed to be sleeping can have harmful effects. Even dim light from light pollution can impair our heart rate and how we metabolise sugar (glucose), may lead to psychiatric disorders such as depression, anxiety and bipolar disorder, and increases the overall risk of premature death.

    The main reason for these harmful effects is that light “at the wrong time” disturbs the body clock, and these effects are more pronounced for “night owls”.

    This “misaligned” exposure to light is also connected to the detrimental health effects we often see in people who work night shifts, such as an increased risk of cancer, diabetes and heart disease.

    How about the gut?

    Digestion also follows a circadian rhythm. Muscles in the colon that help move waste are more active during the day and slow down at night.

    The most significant increase in colon movement starts at 6.30am. This is one of the reasons why most people feel the urge to poo in the early morning rather than at night.

    The gut’s day-night rhythm is a direct result of the action of the gut’s own clock and the central clock (which synchronises the gut with the rest of the body). It’s also influenced by when we eat.

    6.30 on digital display
    At 6.30am, your gut really begins to get going for the day. Rendra Dria Septia Aji/Shutterstock

    How about focusing?

    Our body clock also helps control our attention and alertness levels by changing how our brain functions at certain times of day. Attention and alertness levels improve in the afternoon and evening but dip during the night and early morning.

    Those fluctuations impact performance and can lead to decreased productivity and an increased risk of errors and accidents during the less-alert hours.

    So it’s important to perform certain tasks that require our attention at certain times of day. That includes driving. In fact, disruption of the circadian clock at the start of daylight savings – when our body hasn’t had a chance to adapt to the clocks changing – increases the risk of a car accident, particularly in the morning.

    What else does our body clock control?

    Our body clock influences many other aspects of our biology, including:

    • physical performance by controlling the activity of our muscles
    • blood pressure by controlling the system of hormones involved in regulating our blood volume and blood vessels
    • body temperature by controlling our metabolism and our level of physical activity
    • how our body handles drugs and toxins by controlling enzymes involved in how the liver and kidneys eliminate these substances from the body.
    Driving at night in wet conditions
    If you can, avoid driving long distances at night, as you’ll be less alert. trendobjects/Shutterstock

    Morning light is important

    But what does this all mean for us? Exposure to light, especially in the morning, is crucial for synchronising our circadian clock and bodily functions.

    As well as setting us up for a good night’s sleep, increased morning light exposure benefits our mental health and reduces the risk of obesity. So boosting our exposure to morning light – for example, by going for a walk, or having breakfast outside – can directly benefit our mental and metabolic health.

    However, there are other aspects about which we have less control, including the genes that control our body clock.

    Frederic Gachon, Associate Professor, Physiology of Circadian Rhythms, Institute for Molecular Bioscience, The University of Queensland and Benjamin Weger, NHMRC Emerging Leadership Fellow Institute for Molecular Bioscience, The University of Queensland

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Apricot vs Passion Fruit – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing apricots to passion fruit, we picked the passion fruit.

    Why?

    Both are great! But…

    In terms of macros, passion fruit has more than 5x the fiber and 2x the carbs, making it an easy win in this category (it also has more protein and fat, but those numbers/differences are small enough to not really make a meaningful health difference).

    In the category of vitamins, apricots have more of vitamins A, B1, B5, E, and K, while passion fruit has more of vitamins B2, B3, B6, B9, C, and choline. A more modest win for passion fruit here!

    When it comes to minerals, apricots have more zinc, while passion fruit has more copper, iron, magnesium, phosphorus, potassium, and selenium; a clear win for passion fruit.

    Looking at phytochemicals, the most relevant factor here is apricots’ lycopene content, so they get a win on this one.

    Adding up the sections makes for a clear overall win for passion fruit, but by all means enjoy either or both; diversity is good!

    Want to learn more?

    You might like:

    Top 8 Fruits That Prevent & Kill Cancer

    Enjoy!

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  • Why Is Rabies The Most Lethal Infectious Disease?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    We may not hear of epidemics or pandemics, but…

    In bite-size terms…

    Rabies is caused by viruses in the Lyssavirus genus, especially the classical rabies virus, which infects the mammalian nervous system and thus can (and all-too-often does) spread through mammals.

    Transmission usually occurs through saliva entering tissue via a bite, but even just saliva contacting vulnerable areas can also pose a risk, and infections closer to the head can progress more quickly because the virus travels towards the brain through nerves.

    Why rabies is hard to stop: rabies virions can remain hidden for days, months, or (rarely) even years, while suppressing parts of the immune response, and travel inside nerve cells at up to 10cm per day, which helps shield them from immune defenses too.

    Once the virus reaches the central nervous system, symptoms begin rapidly as the infection spreads through nervous tissue, initially causing flu-like illness before progressing into severe neurological disease.

    Why rabies is so deadly: rabies viruses usually avoid triggering strong inflammation in the brain, preventing immune cells and many therapies from reaching infected tissue effectively, and once symptoms appear, rabies is almost always fatal.

    Pre-exposure and post-exposure rabies vaccinations are highly effective if (and usually only if) administered before symptoms develop, preventing the virus from reaching the central nervous system. In contrast, very few people have survived symptomatic rabies, usually after intensive medical care and often with lasting neurological damage.

    For this reason, even merely possible exposures, such as waking to find a bat in a bedroom, merit urgent medical evaluation—precisely because rabies prevention is only reliably effective before symptoms begin.

    For more on all of this, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like:

    Lyssavirus is rare, but deadly. What should you do if a bat bites you?

    Take care!

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  • Nudge – by Richard Thaler & Cass Sunstein

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    How often in life do we make a suboptimal decision that ends up plaguing us for a long time afterwards? Sometimes, a single good or bad decision can even directly change the rest of our life.

    So, it really is important that we try to optimize the decisions we do make.

    Professors Richard Thaler and Cass Sunstein look at all kinds of decision-making in this book. Their goal, as per the subtitle, is “improving decisions about health, wealth, and happiness”.

    For the most part, the book concentrates on “nudges”. Small factors that influence our decisions one way or another.

    Most importantly: that some of them are very good reasons to be nudged; others, very bad ones. And they often look similar.

    Where this book excels is in highlighting the many ways we make decisions without even thinking about it… or we think about it, but only down a prescribed, foreseen track, to an externally expected conclusion (for example, an insurance company offering three packages, but two of them exist only to direct you to the “correct” choice).

    A weakness of the book is that in some aspects it’s a little inconsistent. The authors describe their economic philosophy as “libertarian paternalism”, and as libertarians they’re against mandates, except when as paternalists they’re for them. But, if we take away their labels, this boils down to “some mandates can be good and some can be bad”, which would not be so inconsistent after all.

    Bottom line: if you’d like to better understand your own decision-making processes through the eyes of policy-setting economists (especially Sunstein, who worked for the White House Office of Information & Regulatory Affairs) whose job it is to make sure you make the “right” decisions, then this is a very enlightening book.

    Click here to check out Nudge and improve your decision-making clarity!

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  • The Sprout Book – by Doug Evans

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Sprouting seeds are more nutritious than most people think, and “seeds” is also a much broader category than people think. Beyond even chia and sunflower and such, this book bids us remember that onions do not just appear on supermarket shelves fully formed (to give just one example of many); most plants come from seeds and of those, most can be usefully sprouted.

    The author, most well-known for his tech companies, here is selling us a very low-tech health kick with very little profit to be found except for our health. By sprouting seeds of many kinds at home, we can enjoy powerful superfoods that are not only better than, but also cheaper than, most supplements.

    Nor are the benefits of sprouting things marginal; we’re not talking about a 1–10% increase in bioavailable so much as what’s often a 100–1000% increase.

    After explaining the science and giving a primer on sprouting things for oneself, there is a wide selection of recipes, but the biggest benefit of the book is in just getting the reader up-and-running with at-home sprouting.

    Bottom line: if you like the idea of letting food be your medicine and even like the idea of essentially growing your own food with zero gardening skills, then this is an excellent book for you.

    Click here to check out The Sprout Book, and get sprouting!

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  • How To Look After Your Health When Your Life Falls Apart

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Dr. Ruth Machin of “Wise Woman Wellbeing” is here with advice from recent experience:

    Holding it together

    For Dr. Machin, grief after her father’s death understandably disrupted her previously consistent habits like regular exercise, healthy eating, and 7–8 hours of sleep, leading to poor sleep, reduced appetite, increased cravings, and less movement.

    These sorts of things tend to unravel together, because stress and poor sleep raise cortisol and adrenaline levels, increase the hunger hormone ghrelin, and impair decision-making, which in turn drives cravings for high-fat, sugar, and salty foods, thus causing multiple habits to collapse in a chain reaction.

    In other words, these habit lapses don’t happen in isolation, but rather stack on top of each other, making it harder to restart, and turning a short disruption into a prolonged break from routines.

    • What to not do: the all-or-nothing approach fails because waiting for the “right time” delays action indefinitely, while going all-in sets unrealistic standards that lead to overwhelm and burnout.
    • What to do instead: adopting a “minimum viable routine” reframes health as part of your identity by maintaining small, consistent actions even during difficult periods.

    The core principle here is that consistency matters more than perfection, especially during challenging times when maintaining anything is more valuable than aiming for ideal habits and ending up crashing and burning instead.

    So, she recommends to identify the smallest reasonably possible set of daily actions that support your physical and mental health, and keep them going regardless of circumstances.

    This is critical, because maintaining even minimal habits during hard times prevents complete resets, making it easier to return to fuller routines when life stabilizes.

    For more on all of this, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like:

    Take care!

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