Uric Acid’s Extensive Health Impact (And How To Lower It)

10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

Uric Acid’s Extensive Health Impact (And How To Lower It)

This is Dr. David Perlmutter. He’s a medical doctor, and a Fellow of the American College of Nutrition. He’s a member of the Editorial Board for the Journal of Alzheimer’s Disease, and has been widely published in many other peer-reviewed journals.

What does he want us to know?

He wants us to know about the health risks of uric acid (not something popularly talked about so much!), and how to reduce it.

First: what is it? Uric acid is a substance we make in our own body. However, unlike most substances we make in our body, we have negligible use for it—it’s largely a waste product, usually excreted in urine.

However, if we get too much, it can build up (and crystallize), becoming such things as kidney stones, or causing painful inflammation if it shows up in the joints, as in gout.

More seriously (unpleasant as kidney stones and gout may be), this inflammation can have a knock-on effect triggering (or worsening) other inflammatory conditions, ranging from non-alcoholic fatty liver disease, to arthritis, to dementia, and even heart problems. See for example:

How can we reduce our uric acid levels?

Uric acid is produced when we metabolize purine nucleotides, which are found in many kinds of food. We can therefore reduce our uric acid levels by reducing our purine intake, as well as things that mess up our liver’s ability to detoxify things. Offsetting the values for confounding variables (such as fiber content, or phytochemicals that mitigate the harm), the worst offenders include…

Liver-debilitating things:

  • Alcohol (especially beer)
  • High-fructose corn syrup (and other fructose-containing things that aren’t actual fruit)
  • Other refined sugars
  • Wheat / white flour products (this is why beer is worse than wine, for example; it’s a double-vector hit)

Purine-rich things:

  • Red meats and game
  • Organ meats
  • Oily fish, and seafood (great for some things; not great for this)

Some beans and legumes are also high in purines, but much like real fruit has a neutral or positive effect on blood sugar health despite its fructose content, the beans and legumes that are high in purines, also contain phytochemicals that help lower uric acid levels, so have a beneficial effect.

Eggs (consumed in moderation) and tart cherries have a uric-acid lowering effect.

Water is important for all aspects of health, and doubly important for this.

Hydrate well!

Lifestyle matters beyond diet

The main key here is metabolic health, so Dr. Perlmutter advises the uncontroversial lifestyle choices of moderate exercise and good sleep, as well as (more critically) intermittent fasting. We wrote previously on other things that can benefit liver health:

How To Unfatty A Fatty Liver

…in this case, that means the liver gets a break to recuperate (something it’s very good at, but does need to get a chance to do), which means that while you’re not giving it something new to do, it can quickly catch up on any backlog, and then tackle any new things fresh, next time you start eating.

Want to know more about this from Dr. Perlmutter?

You might like his article:

An Integrated Plan for Lowering Uric Acid ← more than we had room for here; he also talks about extra things to include in your diet/supplementation regime for beneficial effects!

And/or his book:

Drop Acid: The Surprising New Science of Uric Acid―The Key to Losing Weight, Controlling Blood Sugar, and Achieving Extraordinary Health

…on which much of today’s main feature was based.

Take care!

Don’t Forget…

Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

Recommended

  • What Is “75 Hard”?
  • Breakfasting For Health?
    Optimal breakfast time: around 10am. Late-night eating may hinder fasting benefits. Prioritize morning meals for circadian rhythm and intermittent fasting benefits.

Learn to Age Gracefully

Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:

  • Stay off My Operating Table – by Dr. Philip Ovadia

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    With heart disease as the #1 killer worldwide, and 88% of adults being metabolically unhealthy (leading cause of heart disease), this is serious!

    Rather than taking a “quick fix” advise-and-go approach, Dr. Ovadia puts the knowledge and tools in our hands to do better in the long term.

    As a heart surgeon himself, his motto here is:

    ❝What foods to put on your table so you don’t end up on mine❞

    There’s a lot more to this book than the simple “eat the Mediterranean diet”:

    • While the Mediterranean diet is generally considered the top choice for heart health, he also advises on how to eat healthily on all manner of diets… Carnivore, Keto, Paleo, Atkins, Gluten-Free, Vegan, you-name-it.
    • A lot of the book is given to clearing up common misconceptions, things that sounded plausible but are just plain dangerous. This information alone is worth the price of the book, we think.
    • There’s also a section given over to explaining the markers of metabolic health, so you can monitor yourself effectively
    • Rather than one-size-fits-all, he also talks about common health conditions and medications that may change what you need to be doing
    • He also offers advice about navigating the health system to get what you need—including dealing with unhelpful doctors!

    Bottom line: A very comprehensive (yet readable!) manual of heart health.

    Get your copy of Stay Off My Operating Table from Amazon today!

    Share This Post

  • Tuna Steak with Protein Salad

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Yes, it’s protein on protein today, and it’s all healthy.

    You will need (per person)

    • 1 tuna steak
    • 1 400g/12oz can mixed beans, drained & rinsed
    • 1 tsp capers
    • 2 tsp black pepper, coarse ground
    • 1 red chili, chopped
    • 1 lime, cut into wedges
    • ½ tsp white wine vinegar
    • Extra virgin olive oil, for cooking
    • Garnish: chopped parsley

    Method

    (we suggest you read everything at least once before doing anything)

    1) Put the beans in a bowl, mixing in the capers, vinegar, and 1 tsp of the black pepper

    2) Gently rub a little olive oil onto each side of the tuna steak, and season with the remainder of the black pepper (as in, the other tsp, not the rest of what you have in the house).

    3) Heat a ridged grill pan until hot, and then cook the tuna for around 3 minutes on each side. Do not jiggle it! Do not slide it, and definitely do not stir it. Just gently turn it over when necessary. The edges should be cooked, and the inside should still be pink (it’s easy to forget when it comes from a can, but remember tuna is usually eaten raw)

    4) Serve, sprinkling with the chopped chili and garnishing with the parsley. The lime wedges go on the side for squeezing at the table.

    Enjoy!

    Want to learn more?

    For those interested in some of the science of what we have going on today:

    Take care!

    Share This Post

  • Delicious Daily Daal

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    You’re not obliged to eat this every day, but you might want to. The reason we called this one this, is because it’s a super simple recipe (don’t be put off by the long ingredients list; it’s mostly spices making it look long) which, after you’ve done it a couple of times, you could practically do it in your sleep quickly and easily.

    The name “lentil daal” is a bit like “naan bread”—a redundant tautology repeated more than once unnecessarily, but it helps for international clarity. The dish is usually served with naan, by the way, and rice. We don’t have room for those today, maybe we’ll do them another day; for now, you can just cook rice how you normally do, and buy naan if necessary.

    Writer’s note: I love strong flavors; many people don’t. For this reason I’m going to give a “basic” version. Please feel free to multiply the spices if you feel so inclined. Where I give “one teaspoon” of a spice below, I’d use a tablespoon at home. Chili peppers can vary in heat a lot even within the same type, so what I do for any given batch is taste one (raw), judge the heat, and use an appropriate number of peppers accordingly. If you don’t want to do that, I suggest just guessing low (as per the instructions below) and if you find at the end you want more heat, you can always stir in a little hot sauce. I know that sounds heretical, but at the end of the day, the primary goal of cooking is to have the meal you want at the end of it.

    You will need

    • 1 1/2 cups red lentils
    • 1 large onion, chopped
    • 1 large bulb garlic, minced
    • 1 oz ginger, grated
    • 2 hot peppers (e.g. serrano), chopped
    • 1 tsp ground cumin
    • 1 tsp ground coriander
    • 1 tsp ground turmeric
    • 1 tsp garam masala (this is also ground, but it doesn’t come any other way)
    • 1 tsp chili flakes (omit if you’re not a fan of heat)
    • 2 tsp cracked black pepper
    • 1 tsp salt ← I wouldn’t recommend multiplying this one unless later, to taste. In fact, instead of 1 tsp salt I use 2 tsp MSG, which has less sodium than 1 tsp salt. But “1 tsp salt” is the “easy to find in the store” version.
    • 2 large or 3 small tomatoes, chopped (or 1 can chopped tomatoes)
    • 2 shallots, thinly sliced
    • 1 tsp cumin seeds
    • 1 tsp mustard seeds
    • 1 tsp coriander seeds
    • 1 tsp black peppercorns
    • 1 lime
    • 1/2 cup fresh cilantro, or if you have the “that tastes like soap” gene, parsley, chopped
    • Coconut oil for cooking (if you don’t like coconut, consider springing for avocado oil—if you use olive oil, it’ll add an olivey taste which changes the dish a lot; not inherently bad, but it feels a lot less like traditional daal; seed oils are less healthy and we don’t recommend them; ghee is a traditional option and not bad in moderation, but not as healthy as the oils we mentioned first)
    • Water for cooking the lentils

    Method

    (we suggest you read everything at least once before doing anything)

    1) In a saucepan, boil water and add the lentils; let them simmer while doing the next things.

    2) Sauté the onions until translucent. This should only take a few minutes.

    3) Add the garlic, ginger, and hot peppers, and keep stirring for another couple of minutes.

    4) Add the ground spices (cumin, coriander, turmeric, garam masala) chili flakes, and cracked black pepper, as well as the salt or MSG if using (not both), and stir them in quickly but thoroughly.

    For the next step, you may need to transfer to larger pan if your sauté pan isn’t big enough to take the volume; if so, that’s fine, the sauté has done its job and can have a rest now. If your sauté pan is big enough, just carry on in the same pan; this is perfect.

    5) Add the lentils with the water you cooked them in (there might not be much water left now, as the lentils will have absorbed a lot of it; this is fine) as well as the chopped tomatoes.

    6) Simmer until it has the consistency of a very thick sauce (you can add a splash more water here and there if it seems to need more). In the West it’s common to serve lentils “al dente”, but in the East it’s usual to (for dishes like this) cook them until they start to

    7) Add the juice of at least 1/2 of your lime, or the whole lime if you feel so inclined.

    8) In a pre-heated skillet, flash-fry the sliced shallots and the seeds (cumin, coriander, mustard, black peppercorns) at the hottest temperature you can muster. Don’t worry if the oil smokes; we’re only going to be at this tadka-making stage for a moment and nothing will stick provided you keep it moving. When the seeds start popping, it’s ready. Add it all to the big pan and stir in.

    9) Add the cilantro-or-parsley garnish once you’re ready to serve.

    Enjoy!

    Learn more

    For those interested in some of the science of what we have going on today:

    Take care!

    Share This Post

Related Posts

  • What Is “75 Hard”?
  • Cross That Bridge – by Samuel J. Lucas

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Books of this genre usually have several chapters of fluff before getting to the point. You know the sort:

    1. Let me tell you about some cherry-picked celebrity stories that overlook survivorship bias
    2. Let me tell you my life story, the bad parts
    3. My life story continued, the good parts now
    4. What this book can do for you, an imaginative pep talk that keeps circling back to me

    …then there will be two or three chapters of the actual advertised content, and then a closing chapter that’s another pep talk.

    This book, in contrast, throws that out of the window. Instead, Lucas provides a ground-up structure… within which, he makes a point of giving value in each section:

    • exercises
    • summaries
    • actionable advice

    For those who like outlines, lists, and overviews (as we do!), this is perfect. There are also plenty of exercises to do, so for those who like exercises, this book will be great too!

    Caveat: occasionally, the book’s actionable advices are direct but unclear, for example:

    • Use the potential and power of tea, to solve problems

    Context: there was no context. This was a bullet-pointed item, with no explanation. It was not a callback to anything earlier; this is the first (and only) reference to tea.

    However! The book as a whole is a treasure trove of genuine tips, tools, and voice-of-experience wisdom. Occasional comments may leave you scratching your head, but if you take value from the rest, then the book was already more than worth its while.

    Get Your Copy of Cross That Bridge on Amazon Today!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:

  • Mimosa For Healing Your Body & Mind

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Today we’re looking at mimosa (no relation to the cocktail!), which is a name given to several related plant species that belong to the same genus or general clade, look similar, and have similar properties and behavior.

    As a point of interest that’s not useful: mimosa is one of those plants whereby if you touch it, it’ll retract its leaves and shrink away from you. The leaves also droop at nighttime (perfectly healthily; they’re not wilting or anything; this too is just plant movement), and spring back up in the daytime.

    So that’s what we mean when we say “and behavior” 😉

    Antidepressant & anxiolytic

    Mimosa bark and leaves have long been used in Traditional Chinese Medicine, as well as (albeit different species) in the North-East of Brazil, and (again, sometimes different species) in Mexico.

    Animal studies, in vivo studies, and clinical practice in humans, have found this to be effective, for example:

    ❝[Mimosa pudica extract] has anti-anxiety, anti-depressant and memory enhancing activities that are mediated through multiple mechanisms❞

    Source: Effects of Mimosa pudica L. leaves extract on anxiety, depression and memory

    Research is ongoing with regard to how, exactly, mimosa does what it does. Here’s a paper about another species mimosa:

    Molecular basis and mechanism of action of Albizia julibrissin in depression treatment and clinical application of its formulae

    (notwithstanding the genus name, it’s still part of the mimosa clade)

    Anti-inflammatory & analgesic

    In this case, mimosa has traditionally been used as a topical tincture (for skin damage of many kinds, ranging from cuts and abrasions to burns to autoimmune conditions and more), so what does the science say about that?

    ❝In summary, the present study provided evidence that the [mimosa extract], its fractions and the isolated compound sakuranetin showed significant anti-inflammatory and antinociceptive activities❞

    Read in full: Antinoceptive and Anti-inflammatory Activities of the Ethanolic Extract, Fractions and Flavones Isolated from Mimosa tenuiflora (Willd.) Poir (Leguminosae)

    Wound healing

    About those various skin damages, here’s another application, and a study showing that it doesn’t just make it feel better, it actually helps it to heal, too:

    ❝Therapeutic effectiveness occurred in all patients of the extract group; after the 8th treatment week, ulcer size was reduced by 92% as mean value in this group, whereas therapeutic effectiveness was observed only in one patient of the control group (chi(2), p=0.0001). No side effects were observed in any patient in either group.❞

    Very compelling stats!

    Read more: Therapeutic effectiveness of a Mimosa tenuiflora cortex extract in venous leg ulceration treatment

    Is it safe?

    Yes, for most people, with some caveats:

    1. this one comes with a clear “don’t take if pregnant or breastfeeding” warning, as for unknown reasons it has caused a high incidence of fetal abnormalities or fetal death in animal studies.
    2. while the stem bark (the kind used in most mimosa supplements and most readily found online) has negligible psychoactivity, as do many species of mimosa in general, the root of M. tenuiflora has psychedelic effects similar to ayahuasca if taken orally, for example as a decoction, if in the presence of a monoamine oxidase inhibitor (MAOI), as otherwise MAO would metabolize the psychoactive component in the gut before it can enter the bloodstream.

    That’s several “ifs”, meaning that the chances of unwanted psychedelic effects are slim if you’re paying attention, but as ever, do check with your doctor/pharmacist to be sure.

    Want to try some?

    We don’t sell it, but here for your convenience is an example product on Amazon 😎

    Enjoy!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:

  • Hard to Kill – by Dr. Jaime Seeman

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    We’ve written before about Dr. Seeman’s method for robust health at all ages, focussing on:

    • Nutrition
    • Movement
    • Sleep
    • Mindset
    • Environment

    In this book, she expands on these things far more than we have room to in our little newsletter, including (importantly!) how each interplays with the others. She also follows up with an invitation to take the “Hard to Kill 30-Day Challenge”.

    That said, in the category of criticism, it’s only 152 pages, and she takes some of that to advertise her online services in an effort to upsell the reader.

    Nevertheless, there’s a lot of worth in the book itself, and the writing style is certainly easy-reading and compelling.

    Bottom line: this book is half instructional, half motivational, and covers some very important areas of health.

    Click here to check out “Hard to Kill”, and enjoy robust health at every age!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails: