The Vicious Cycle Of CKM Syndrome

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About 90% of American adults have never heard of cardiovascular-kidney-metabolic (CKM) syndrome—an interconnected health condition that affects nearly 90% of American adults through combinations of heart disease, kidney disease, diabetes, and poor energy metabolism.

Source: About 9 in 10 haven’t heard of condition that affects nearly 90% of U.S. adults, survey reveals

Why these things go together and why that matters

Our body is a “system of systems”, including:

  • a countless number of cells (most of them not human) working together to continually make us us
  • ecosystems like our various microbiomes (gut being most talked-about and far-reaching in its effects, but also oral, skin, vaginal, and so forth)
  • a very complex interplay of hormones in our endocrine system
  • large-scale systems like the nervous systems, circulatory systems, immune systems, etc, and yes those are all in the plural because we categorically have more than one of each
  • and more, we could go on all day, depending on how we categorize them

All this means that if one system goes wrong, the others will soon start to have problems, and we really don’t have any systems that are expendable.

So, what happens if one system does start failing?

According to the same American Heart Association poll as gave the “90% of American adults don’t know about this” figure,

  • 68% of respondents mistakenly thought the best approach is to manage each condition separately or were unsure
  • 42% believed a healthy heart wouldn’t likely be affected by other organs or weren’t sure

However…

As just one example, there’s a two-way relationship between heart and kidneys:

  1. The heart pumps blood to the body
  2. The metabolic system turns glucose (sugar) from the blood into energy
  3. The process of metabolism dumps waste back into the blood
  4. The kidneys filter waste from the blood and balance fluids, which helps with blood pressure
  5. Blood pressure affects how the heart pumps blood into the body

When this feedback loop goes bad, this is cardiovascular-kidney-metabolic (CKM) syndrome.

So, what to do about it?

The AHA recommend focusing on 4 specific things; we’ll mention them and in each case share one of our main features about that topic:

  1. Healthy blood pressure: Hypertension: Factors Far More Relevant Than Salt
  2. Healthy blood sugars: Improve Your Insulin Sensitivity!
  3. Healthy cholesterol levels: Lower Cholesterol Naturally
  4. Healthy body weight: How To Lose Weight (Healthily!)

For less information, see also the AHA’s press release: Paying attention to four health factors can help prevent CKM syndrome

Want to do more?

Check out:

Are your Kidneys Ok? Detect Early To Protect Kidney Health (Here’s How) ← especially relevant if you are over 60

Take care!

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  • Banana vs Guava – Which is Healthier?

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    Our Verdict

    When comparing banana to guava, we picked the guava.

    Why?

    Both are great, but it wasn’t close:

    In terms of macros, bananas have more than 2x the carbs while guavas have more than 2x the fiber and protein; an easy win for guava.

    In the category of vitamins, bananas have more of vitamins B2 and B6, while guavas have a lot more of vitamins A, B1, B3, B5, B7, B9, C, E, and K, sweeping this round easily as well.

    Looking at minerals, bananas have more magnesium, manganese, and selenium, while guavas have more calcium, copper, phosphorus, potassium, and zinc, winning guavas’ third round in a row.

    In other considerations, guavas also have more polyphenols, so that’s another round to guavas.

    Adding up the sections makes for an overwhelming overall win for guavas, but by all means do enjoy either or both, as diversity is best!

    Want to learn more?

    You might like:

    What’s Your Plant Diversity Score?

    Enjoy!

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  • Papaya vs Passion Fruit – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing papaya to passion fruit, we picked the passion fruit.

    Why?

    In terms of macros, passion fruit wins against most contenders with its very high fiber content, and that’s true here too; passion fruit has more than 6x the fiber, as well as about 2x the carbs and more than 4x the protein, giving it an easy win in the macros category.

    In the category of vitamins, papaya has more of vitamins B9, C, E, and K, while passion fruit has more of vitamins A, B2, B3, B6, and choline. Thus, a marginal win for passion fruit, or perhaps a tie if we want to take into consideration that papaya has 15x the vitamin E content, which is rather more of a margin of different than the rest of the vitamins being compared here.

    When it comes to minerals, things are less balanced again; papaya has more calcium, while passion fruit has more copper, iron, magnesium, manganese, phosphorus, potassium, and zinc. An easy win for passion fruit.

    Adding up the sections makes for a clear overall win for passion fruit, but by all means enjoy either or both; diversity is good!

    Want to learn more?

    You might like:

    What’s Your Plant Diversity Score?

    Enjoy!

    Share This Post

  • Artichoke vs Brussels Sprouts – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing artichoke to Brussels sprouts, we picked the sprouts.

    Why?

    Finally, a vegetable that beats artichoke—after it previously beat many healthy high-scorers including cabbage and even broccoli! It was still close though, which is impressive for artichoke, considering what a nutritional powerhouse Brussels sprouts are:

    In terms of macros, the only meaningful difference is that artichoke has slightly more carbs and fiber, so artichoke gets the most marginal of nominal wins in this category.

    In the category of vitamins, however, artichoke has only more of vitamins B3, and B9, while Brussels sprouts have more of vitamins A, B1, B2, B6, C, E, and K, giving sprouts the clear victory here, especially with much higher margins of difference (e.g. 58x more vitamin A, as well as 7x more vitamin C, and 10x more vitamin K).

    When it comes to minerals, artichoke has more copper, magnesium, phosphorus, and zinc, while Brussels sprouts have more iron, manganese, potassium, and selenium, resulting in a 4:4 tie, and the small margins of difference are mostly comparable, with the exception that sprouts have 8x more selenium. So, Brussels sprouts win this category very marginally on that tie-breaker.

    In other considerations, artichoke has more polyphenols, while the sprouts have sulforaphane, to we’re calling this round a tie on balance.

    Adding up the sections we see that most recent tie, while macros and minerals gave a small win each to artichoke and sprouts respectively, while the vitamins category was an overwhelming win for sprouts, so—with this deciding factor in mind—sprouts win the day today.

    Want to learn more?

    You might like to read:

    Sprout Your Seeds, Grains, Beans, Etc

    Enjoy!

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  • What’s the difference between an eating disorder and disordered eating?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Following a particular diet or exercising a great deal are common and even encouraged in our health and image-conscious culture. With increased awareness of food allergies and other dietary requirements, it’s also not uncommon for someone to restrict or eliminate certain foods.

    But these behaviours may also be the sign of an unhealthy relationship with food. You can have a problematic pattern of eating without being diagnosed with an eating disorder.

    So, where’s the line? What is disordered eating, and what is an eating disorder?

    PIKSEL/Getty

    What is disordered eating?

    Disordered eating describes negative attitudes and behaviours towards food and eating that can lead to a disturbed eating pattern.

    It can involve:

    • dieting
    • skipping meals
    • avoiding certain food groups
    • binge eating
    • misusing laxatives and weight-loss medications
    • inducing vomiting (sometimes known as purging)
    • exercising compulsively.

    Disordered eating is the term used when these behaviours are not frequent and/or severe enough to meet an eating disorder diagnosis.

    Not everyone who engages in these behaviours will develop an eating disorder. But disordered eating – particularly dieting – usually precedes an eating disorder.

    What is an eating disorder?

    Eating disorders are complex psychiatric illnesses that can negatively affect a person’s body, mind and social life. They’re characterised by persistent disturbances in how someone thinks, feels and behaves around eating and their bodies.

    To make a diagnosis, a qualified health professional will use a combination of standardised questionnaires, as well as more general questioning. These will determine how frequent and severe the behaviours are, and how they affect day-to-day functioning.

    Examples of clinical diagnoses include anorexia nervosa, bulimia nervosa, binge eating disorder and avoidant/restrictive food intake disorder.

    How common are eating disorders and disordered eating?

    The answer can vary quite radically depending on the study and how it defines disordered behaviours and attitudes.

    An estimated 8.4% of women and 2.2% of men will develop an eating disorder at some point in their lives. This is most common during adolescence.

    Disordered eating is also particularly common in young people with 30% of girls and 17% of boys aged 6–18 years reporting engaging in these behaviours.

    Although the research is still emerging, it appears disordered eating and eating disorders are even more common in gender diverse people.

    Can we prevent eating disorders?

    There is some evidence eating disorder prevention programs that target risk factors – such as dieting and concerns about shape and weight – can be effective to some extent in the short term.

    The issue is most of these studies last only a few months. So we can’t determine whether the people involved went on to develop an eating disorder in the longer term.

    In addition, most studies have involved girls or women in late high school and university. By this age, eating disorders have usually already emerged. So, this research cannot tell us as much about eating disorder prevention and it also neglects the wide range of people at risk of eating disorders.

    Is orthorexia an eating disorder?

    In defining the line between eating disorders and disordered eating, orthorexia nervosa is a contentious issue.

    The name literally means “proper appetite” and involves a pathological obsession with proper nutrition, characterised by a restrictive diet and rigidly avoiding foods believed to be “unhealthy” or “impure”.

    These disordered eating behaviours need to be taken seriously as they can lead to malnourishment, loss of relationships, and overall poor quality of life.

    However, orthorexia nervosa is not an official eating disorder in any diagnostic manual.

    Additionally, with the popularity of special diets (such as keto or paleo), time-restricted eating, and dietary requirements (for example, gluten-free) it can sometimes be hard to decipher when concerns about diet have become disordered, or may even be an eating disorder.

    For example, around 6% of people have a food allergy. Emerging evidence suggests they are also more likely to have restrictive types of eating disorders, such as anorexia nervosa and avoidant/restrictive food intake disorder.

    However, following a special diet such as veganism, or having a food allergy, does not automatically lead to disordered eating or an eating disorder.

    It is important to recognise people’s different motivations for eating or avoiding certain foods. For example, a vegan may restrict certain food groups due to animal rights concerns, rather than disordered eating symptoms.

    What to look out for

    If you’re concerned about your own relationship with food or that of a loved one, here are some signs to look out for:

    • preoccupation with food and food preparation
    • cutting out food groups or skipping meals entirely
    • obsession with body weight or shape
    • large fluctuations in weight
    • compulsive exercise
    • mood changes and social withdrawal.

    It’s always best to seek help early. But it is never too late to seek help.

    In Australia, if you are experiencing difficulties in your relationships with food and your body, you can contact the Butterfly Foundation’s national helpline on 1800 33 4673 (or via their online chat).

    For parents concerned their child might be developing concerning relationships with food, weight and body image, Feed Your Instinct highlights common warning signs, provides useful information about help seeking and can generate a personalised report to take to a health professional.

    Gemma Sharp, Researcher in Body Image, Eating and Weight Disorders, Monash University

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • The Painkiller That Increases Cognitive Impairment Risk By 85%

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    …and other items from this week’s health news:

    This Common Painkiller Now → Cognitive Decline Within 10 Years?

    We’ll get straight to it: receiving six or more prescriptions of gabapentin for lower back pain is linked to 29% increased risk of dementia and 85% risk of mild cognitive impairment (MCI) within 10 years.

    Because MCI is, by definition, not yet full-blown dementia, that means that those risk increases are not overlapping (because by definition you cannot have both at once), which means they stack, which means you get 29+85 = 114% increased risk of getting one of those two conditions. In other words, your 10-year risk is more than doubled.

    Gabapentin is widely used for chronic neuropathic pain due to low addiction potential (compared to opioids), but since there is a clear association between gabapentin prescriptions and later cognitive decline, it may not be so safe as it was hoped.

    Read in full: Frequent gabapentin use linked to higher dementia and cognitive impairment risk

    Related: Before You Reach For That Tylenol… ← includes a resource list for safer alternatives

    USA Measles epidemic now at 33-year high

    The US has recently recorded a record-breaking 1,288 confirmed measles cases, although of course the actual rate will be much higher. Of these, 750 cases have come from Texas, with additional spread into New Mexico and Oklahoma. The outbreak began in Gaines County, West Texas, which Dr. Peter Hotez attributes to anti-vaccine sentiment and low immunization rates.

    In short, the highly effective MMR vaccine (97% efficacy) is still being underused as childhood vaccination rates continue to fall, leaving whole communities vulnerable to outbreaks. This was possible because recent Texas laws have made it easier to opt out of school vaccine requirements.

    On the wider scale across the nation, there have been dozens of outbreaks this year; 13% of measles cases have required hospitalization, but few deaths so far (the deaths mostly being unvaccinated children).

    Read in full: US measles case count hits 33-year high—and Texas’ outbreak is to blame, suggests vaccine expert

    Related: The Truth About Vaccines

    Fasting and the gut-brain axis

    The news here is that is that intermitting fasting (IF) boosts beneficial gut bacteria, which produce short-chain fatty acids (SCFAs). These in turn help reduce inflammation, strengthen the gut lining, and support better communication between the gut and brain.

    The benefits don’t stop there! You may remember that serotonin is made mostly in the gut. This study also showed that IF improves the production of serotonin and other neurotransmitters by changing how the body processes the amino acid tryptophan. IF therefore helps keep the brain’s internal clock in sync in multiple ways, reducing inflammation in areas of the brain that are sensitive to disrupted schedules—something especially important in aging and neurodegeneration.

    At the cellular level, fasting encourages the brain to switch its fuel source from sugar to ketones, like β-hydroxybutyrate (BHB), which are more efficient and protective. This switch improves energy use in brain cells, boosts antioxidants, and triggers “cellular clean-up” processes like autophagy, which help clear out harmful detritus—a major contributing factor to Alzheimer’s and Parkinson’s disease.

    Not content with just that, the study further showed that IF supports brain repair by increasing levels of brain-derived neurotrophic factor (BDNF).

    In short, there’s a lot to be said for it:

    Read in full: Fasting triggers neuroprotective changes that could delay dementia

    Related: The Alzheimer’s Gut-Brain Connection—Caught On X-Ray!

    Take care!

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  • Age & Strength Loss: What Happens When, & How Much Is Unavoidable?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    When it comes to aging and loss of strength, a lot of focus is placed on loss of muscle mass (sarcopenia).

    We talked about this in our article: Protein vs Sarcopenia: How Much Do We Need, Really?

    And that is important, but it’s not the whole story!

    Strong at every age

    You can be strong at every age, if and only if you’re very intentional about it.

    Researchers (Dr. Maria Westerståhl et al.) followed 427 people for 47 years, repeatedly measuring fitness, strength, muscle endurance, and power from adolescence all the way through into older adulthood.

    First, the bad news: physical performance overall peaks in early adulthood and begins declining at around 26 for women and 36 for men, with initially gradual losses that accelerate with advancing age.

    About that acceleration: aerobic capacity and muscular endurance initially fall by about 0.3–0.6 percent per year, later speeding up to roughly 2.0–2.5 percent per year, and the deterioration in muscle power gets a similar age-related acceleration.

    Next, the worse news: physical power specifically starts its decline even sooner than the other factors, with women having their peak around 19 and men having their peak around 27.

    It does, however, get worse: total losses in physical capacity from peak to age 63 range from 30–48%, which latter end of the range is quite a dramatic loss of physical capacity indeed. Note that that’s the aggregate figure, so we’re not just talking about strength here.

    Is there any good news? Yes: it’s never too late! People who became physically active in adulthood improved physical capacity by about 5–10%, showing that starting later still provides meaningful benefits. To be clear, that’s a net improvement of 5–10%, we’re not talking about shaving 5–10% off the 30–48% loss.

    If you want to go through all these numbers (and more) in detail, here’s the paper: Rise and Fall of Physical Capacity in a General Population: A 47-Year Longitudinal Study

    As for what this means in realistic terms: you’re probably not only not as strong as you used to be, but also not as fit, fast, mobile, and so forth. Your power (explosive power, like sprints or best-effort lifts) and endurance (like long-distance cardio, or isometric holds) are probably not what they used to be either.

    • On the one hand, you can improve them.
    • On the other hand, you do have to actually do it—merely knowing about it will not help if you don’t take action!

    So, how to do that?

    Read on…

    Want to learn more?

    Here are some very good starting points:

    And if you’re really serious about it, then for a much deeper dive than we have room for here, we highly recommend this excellent book we reviewed a while back:

    Unbreakable: A Woman’s Guide to Aging with Power – by Dr. Vonda Wright ← So, she wants us to avoid the train of sarcopenia → osteopenia → osteoporosis → fractures → infections → death, by reducing our risk factors early, and staying more robust and biologically younger.

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

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