The Stress Prescription (Against Aging!)

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The Stress Prescription (Against Aging!)

This is Dr. Elissa Epel, whose work has for the past 20 years specialized in the effect of stress on aging. She’s led groundbreaking research on cortisol, telomeres, and telomerase, all in the context of aging, especially in women, as well as the relationship between stress and weight gain. She was elected member of the National Academy of Medicine for her work on stress pathways, and has been recognized as a key “Influencer in Aging” by the Alliance for Aging Research.

Indeed, she’s also been named in the top 0.1% of researchers globally, in terms of publication impact.

What’s that about stress and aging?

In her words,

❝Women with the highest levels of perceived stress have telomeres shorter on average by the equivalent of at least one decade of additional aging compared to low stress women❞

Source: Accelerated telomere shortening in response to life stress

We say “in her words”, as she is the top-listed author on this paper—an honour reserved for the lead researcher of any given study/paper.

However, we’d be remiss not to note that the second-listed author is Nobel Prize Laureate Dr. Elizabeth Blackburn. What a team! Maybe we’ll do a spotlight feature on Dr. Blackburn’s work one of these days, but for now, back to Dr. Epel…

What does she want us to do about it?

She has the following advice for us:

Let go of what we can’t control

This one is simple enough, and can be as simple as learning how to set anxiety aside, and taking up the practice of radical acceptance of what we cannot control.

Be challenged, not afraid

This is about eustress, and being the lion, not the gazelle. Dr. Epel uses the example of how when lions are hunting gazelles, both are stressed, but both are feeling the physiological effects of that stress in terms of the augmentation to their immediate abilities, but only one of them is suffering by it.

We’ll let her explain how to leverage this:

TED ideas | Here’s how you can handle stress like a lion, not a gazelle | Dr. Elissa Epel

Build resilience through controlled discomfort

Don’t worry, you don’t have to get chased by lions. A cold shower will do it! This is about making use of hormesis, the body’s ability to build resilience to stressors by small doses of controlled cortisol release—as for example when one undergoes thermal shock, which sounds drastic, but for most people, a cold shower (or even an ice bath) is safe enough.

You can read more about this here:

A Cold Shower A Day Keeps The Doctor Away

Connect with nature

You don’t have to hug a tree, but you do have get to a natural (or at least, natural-seeming) environment once in a while. Simply put, we did not evolve to be in the urban or even suburban settings where most of us spend most of our time. Getting to be around greenery with at least some kind of regularity is hugely beneficial. It doesn’t have to be a national park; a nice garden or local park can suffice, and potted plants at home are better than nothing. Even spending time in virtual reality “nature” is an option:

Effect of Virtual Reality on Stress Reduction and Change of Physiological Parameters Including Heart Rate Variability in People With High Stress: An Open Randomized Crossover Trial

(you can see an example there, of the kind of scenery this study used)

Breathe deeply, and rest deeply

Mindful breathing, and good quality sleep, are very strongly evidence-based approaches to reduce stress, for example:

Practice gratitude to build optimism

Optimism has a huge positive impact on health outcomes, even when other factors (including socioeconomic factors, pre-existing conditions, and general reasons for one person to be more optimistic than another) are controlled for.

Read: Optimism and Cause-Specific Mortality: A Prospective Cohort Study

There are various ways to increase optimism, and practising gratitude is one of them—but that doesn’t necessarily mean abandoning realism, either:

How To Practise (Non-Toxic) Positivity

There are other ways too, though, and Dr. Epel discusses some with her friend and colleague, Dr. Elizabeth Blackburn, here:

TED ideas | Could your thoughts make you age faster? And can we reverse that? | Dr. Elizabeth Blackburn & Dr. Elissa Epel

Want to learn more from Dr. Epel?

We reviewed one of her books, The Telomere Effect, previously. It’s about what we can do to lengthen our telomeres (a key factor in health aging; effectively, being biologically younger). You also might enjoy her newer book, The Stress Prescription, as well as her blog.

Enjoy!

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  • Miss Diagnosis: Anxiety, ADHD, & Women

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    It’s Q&A Day at 10almonds!

    Have a question or a request? We love to hear from you!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    ❝Why is ADHD so often misdiagnosed as anxiety in women?❞

    A great question! A short and slightly flippant answer could be “it’s the medical misogyny”:

    Women and Minorities Bear the Brunt of Medical Misdiagnosis

    …and if you’d like to learn more in-depth about this, we recommend this excellent book:

    Unwell Women: Misdiagnosis and Myth in a Man-Made World – by Dr. Elinor Cleghornyou can read our review here

    However, in this case there is more going on too!

    Part of this is because ADHD is, like many psychiatric issues, a collection of symptoms that may or may not all always be present. Since clinical definitions are decided by clinicians, rather than some special natural law of the universe, sometimes this results in “several small conditions in a trenchcoat”, and if one symptom is or isn’t present, it can make things look quite different:

    What’s The Difference Between ADD and ADHD?

    There are two things at hand here: as in the above example, there’s the presence or absence of hyperactivity, but also, that “attention deficit”?

    It’s often not really a deficit of attention, so much as the attention is going somewhere else—an example of naming psychiatric disorders for how they affect other people, rather than the person in question.

    Sidenote: personality disorders really get the worst of this!

    “You have a deep insecurity about never being good enough, and you constantly mess up in your attempt to overcompensate? You may have Evil Bastard Disorder!”

    “You have a crippling fear of abandonment and that you are fundamentally unloveable, so you do all you can to try to keep people close? You must have Manipulative Bitch Disorder!”

    etc

    In the case of ADHD and anxiety and women, a lot of this comes down to how the redirection of focus is perceived:

    ❝For some time, it has been held that women with ADHD are more likely to internalize symptoms and become anxious and depressed and to suffer emotional dysregulation❞

    ~ Dr. Patricia Quinn

    Source: Attention-deficit/hyperactivity disorder and its comorbidities in women and girls: An evolving picture

    This internalization of symptoms, vs the externalization more generally perceived in boys and men, is more likely to be seen as anxiety.

    Double standards also abound for social reasons, e.g:

    • He is someone who thinks ten steps ahead and covers all bases
    • She is anxious and indecisive and unable to settle on one outcome

    Here’s a very good overview of how this double-standard makes its way into diagnostic processes, along with other built-in biases:

    Miss. Diagnosis: A Systematic Review of ADHD in Adult Women

    Want to learn more?

    We’ve reviewed quite a few books about ADHD, but if we had to pick one to spotlight, we’d recommend this one:

    The Silent Struggle: Taking Charge of ADHD in Adults – by L. William Ross-Child, MLC

    Enjoy! And while we have your attention… Would you like this section to be bigger? If so, send us more questions!

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  • Lemon vs Lime – Which is Healthier?

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    Our Verdict

    When comparing lemons to limes, we picked the lemons.

    Why?

    This one’s simple today. They’re both comparable fruits in most ways, and their macro profiles are almost identical. When it comes to vitamins, however, they stand apart a little.

    Both are most well-known for their vitamin C content, but lemons contain about 2x the vitamin C of limes.

    In other vitamins, they’re not too far apart. Technically limes have 2x the vitamin A, but this doesn’t count for much because it’s a case of “two times almost nothing is still almost nothing”.

    In the category of minerals, neither fruit is a very good source of most minerals, and the minerals they do have, are mostly more or less the same.

    Both are acidic, and this can have blood sugar benefits in both cases (and, if not careful, damage tooth enamel in both cases). Nothing to set either apart from the other here.

    So, it comes down to the vitamin C! In which category, lemons take the prize with their higher content.

    Want to learn more?

    You might like to read:

    10 Ways To Balance Blood Sugars ← where it talks about the use of vinegar here, it’s about the acidity, so lemon juice or lime juice is an option too!

    Take care!

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  • Lime-Charred Cauliflower Popcorn

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    Called “popcorn” for its appearance and tasty-snackness, this one otherwise bears little relation to the usual movie theater snack, and it’s both tastier and healthier. All that said, it can be eaten on its own as a snack (even with a movie, if you so wish), or served as one part of a many-dish banquet, or (this writer’s favorite) as a delicious appetizer that also puts down a healthy bed of fiber ready for the main course to follow it.

    You will need

    • 1 cauliflower, cut into small (popcorn-sized) florets
    • 2 tbsp extra virgin olive oil
    • 1 tbsp lime pickle
    • 1 tsp cumin seeds
    • 1 tsp smoked paprika
    • 1 tsp chili flakes
    • 1 tsp black pepper, coarse ground
    • ½ tsp ground turmeric

    Method

    (we suggest you read everything at least once before doing anything)

    1) Preheat your oven as hot as it will go

    2) Mix all the ingredients in a small bowl except the cauliflower, to form a marinade

    3) Drizzle the marinade over the cauliflower in a larger bowl (i.e. big enough for the cauliflower), and mix well until the cauliflower is entirely, or at least almost entirely, coated. Yes, it’s not a lot of marinade but unless you picked a truly huge cauliflower, the proportions we gave will be enough, and you want the end result to be crisp, not dripping.

    4) Spread the marinaded cauliflower florets out on a baking tray lined with baking paper. Put it in the oven on the middle shelf, so it doesn’t cook unevenly, but keeping the temperature as high as it goes.

    5) When it is charred and crispy golden, it’s done—this should take about 20 minutes, but we’ll say ±5 minutes depending on your oven, so do check on it periodically—and time to serve (it is best enjoyed warm).

    Enjoy!

    Want to learn more?

    For those interested in some of the science of what we have going on today:

    Take care!

    Share This Post

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    Q&A with the 10almonds Team

    Q: Very interested in this article on CBD oil in the states. hope you do another one in the future with more studies done on people and more information on what’s new as far as CBD oil goes

    A: We’re glad you enjoyed it! We’ll be sure to revisit CBD in the future—partly because it was a very popular article, and partly because, as noted, there is a lot going on there, research-wise!

    And yes, we prefer human studies rather than mouse/rat studies where possible, too, and try to include those where we find them. In some cases, non-human animal studies allow us to know things that we can’t know from human studies… because a research institution’s ethics board will greenlight things for mice that it’d never* greenlight for humans.

    Especially: things that for non-human animals are considered “introduction of external stressors” while the same things done to humans would be unequivocally called “torture”.

    Animal testing in general is of course a moral quagmire, precisely because of the suffering it causes for animals, while the research results (hopefully) can be brought to bear to reduce to suffering of humans. We’re a health and productivity newsletter, not a philosophical publication, but all this to say: we’re mindful of such too.

    And yes, we agree, when studies are available on humans, they’re always going to be better than the same study done on mice and rats.

    As a topical aside, did you know there’s a monument to laboratory mice and all they’ve (however unintentionally) done for us?

    ❝The quirky statue depicts an anthropomorphic mouse as an elderly woman, complete with glasses balanced atop its nose. Emerging from two knitting needles in its hands is the recognizable double-helix of a strand of DNA.❞

    ~ Smithsonian Magazine

    See The Statue For Yourself Here!

    Don’t Forget…

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    Learn to Age Gracefully

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  • Delay Ageing – by Dr. Colin Rose

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    Note: the title is spelled that way because it is British English. We generally write in US English here at 10almonds, but we’ll first quote directly from Dr. Rose as written:

    ❝I have written Delay Ageing because there is some very important recent University research on ageing and age related illness that deserves to be made accessible to a general audience.❞

    What is this research? Well, there’s quite a lot over its 300-odd pages (exact number depends on the edition and whether we count end matter), and most of it is tweaks and refinements on things with which you’ll probably be at least brushingly familiar if you’re a regular 10almonds reader.

    Dr. Rose addresses the nine hallmarks of aging, of which there are ten, ranging from such things as “telomeres get shorter” and “DNA accumulates damage”, to “stem cells become exhausted” and “cells fail to communicate properly”, and asks the question “what if we were to target all these things simultaneously?”.

    Rather than going for drugs on drugs on drugs (half of them to deal with undesired side effects of the previous ones), Dr. Cole leaves no stone unturned to find lifestyle interventions that will improve each of these, even if just a little. Because, all those “little” improvements add up and even compound, and on the flipside, mean that factors of aging aren’t adding up and compounding so much or so quickly anymore.

    The rather broad umbrella of “lifestyle interventions” obviously includes food under its auspices, and with it, nutraceuticals. So to give one example, if you’re taking a fisetin supplement (a natural senolytic agent), you’ll find science vindicating that here. And much more.

    The style is… Less pop-science and more “textbook written for laypersons”, and you may be thinking “isn’t that the same?” and the difference is that the textbook has a lot less polish and finesse, but often more precise information.

    Bottom line: if you’d like to combat aging on 10 different fronts with easily implementable lifestyle interventions, and know exactly what is doing what and how, then this is the book for you.

    Click here to check out Delay Ageing, and delay aging!

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    Learn to Age Gracefully

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  • Fat’s Real Barriers To Health

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Fat Justice In Healthcare

    This is Aubrey Gordon, an author, podcaster, and fat justice activist. What does that mean?

    When it comes to healthcare, we previously covered some ideas very similar to her work, such as how…

    There’s a lot of discrimination in healthcare settings

    In this case, it often happens that a thin person goes in with a medical problem and gets treated for that, while a fat person can go in with the same medical problem and be told “you should try losing some weight”.

    Top tip if this happens to you… Ask: “what would you advise/prescribe to a thin person with my same symptoms?”

    Other things may be more systemic, for example:

    When a thin person goes to get their blood pressure taken, and that goes smoothly, while a fat person goes to get their blood pressure taken, and there’s not a blood pressure cuff to fit them, is the problem the size of the person or the size of the cuff? It all depends on perspective, in a world built around thin people.

    That’s a trivial-seeming example, but the same principle has far-reaching (and harmful) implications in healthcare in general, e.g:

    • Surgeons being untrained (and/or unwilling) to operate on fat people
    • Getting a one-size-fits-all dose that was calculated using average weight, and now doesn’t work
    • MRI machines are famously claustrophobia-inducing for thin people; now try not fitting in it in the first place

    …and so forth. So oftentimes, obesity will be correlated with a poor healthcare outcome, where the problem is not actually the obesity itself, but rather the system having been set up with thin people in mind.

    It would be like saying “Having O- blood type results in higher risks when receiving blood transfusions”, while omitting to add “…because we didn’t stock O- blood”.

    Read more on this topic: Shedding Some Obesity Myths

    Does she have practical advice about this?

    If she could have you understand one thing, it would be:

    You deserve better.

    Or if you are not fat: your fat friends deserve better.

    How this becomes useful is: do not accept being treated as the problem!

    Demand better!

    If you meekly accept that you “just need to lose weight” and that thus you are the problem, you take away any responsibility from your healthcare provider(s) to actually do their jobs and provide healthcare.

    See also Gordon’s book, which we’ve not reviewed yet but probably will one of these days:

    “You Just Need to Lose Weight”: And 19 Other Myths About Fat People – by Aubrey Gordon

    Are you saying fat people don’t need to lose weight?

    That’s a little like asking “would you say office workers don’t need to exercise more?”; there are implicit assumptions built into the question that are going unaddressed.

    Rather: some people might benefit healthwise from losing weight, some might not.

    In fact, over the age of 65, being what is nominally considered “overweight” reduces all-cause mortality risk.

    For details of that and more, see: When BMI Doesn’t Measure Up

    But what if I do want/need to lose weight?

    Gordon’s not interested in helping with that, but we at 10almonds are, so…

    Check out: Lose Weight, But Healthily

    Where can I find more from Aubrey Gordon?

    You might enjoy her blog:

    Aubrey Gordon | Your Fat Friend

    Or her other book, which we reviewed previously:

    What We Don’t Talk About When We Talk About Fat – by Aubrey Gordon

    Enjoy!

    Don’t Forget…

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    Learn to Age Gracefully

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