The Stress Prescription (Against Aging!)

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The Stress Prescription (Against Aging!)

This is Dr. Elissa Epel, whose work has for the past 20 years specialized in the effect of stress on aging. She’s led groundbreaking research on cortisol, telomeres, and telomerase, all in the context of aging, especially in women, as well as the relationship between stress and weight gain. She was elected member of the National Academy of Medicine for her work on stress pathways, and has been recognized as a key “Influencer in Aging” by the Alliance for Aging Research.

Indeed, she’s also been named in the top 0.1% of researchers globally, in terms of publication impact.

What’s that about stress and aging?

In her words,

❝Women with the highest levels of perceived stress have telomeres shorter on average by the equivalent of at least one decade of additional aging compared to low stress women❞

Source: Accelerated telomere shortening in response to life stress

We say “in her words”, as she is the top-listed author on this paper—an honour reserved for the lead researcher of any given study/paper.

However, we’d be remiss not to note that the second-listed author is Nobel Prize Laureate Dr. Elizabeth Blackburn. What a team! Maybe we’ll do a spotlight feature on Dr. Blackburn’s work one of these days, but for now, back to Dr. Epel…

What does she want us to do about it?

She has the following advice for us:

Let go of what we can’t control

This one is simple enough, and can be as simple as learning how to set anxiety aside, and taking up the practice of radical acceptance of what we cannot control.

Be challenged, not afraid

This is about eustress, and being the lion, not the gazelle. Dr. Epel uses the example of how when lions are hunting gazelles, both are stressed, but both are feeling the physiological effects of that stress in terms of the augmentation to their immediate abilities, but only one of them is suffering by it.

We’ll let her explain how to leverage this:

TED ideas | Here’s how you can handle stress like a lion, not a gazelle | Dr. Elissa Epel

Build resilience through controlled discomfort

Don’t worry, you don’t have to get chased by lions. A cold shower will do it! This is about making use of hormesis, the body’s ability to build resilience to stressors by small doses of controlled cortisol release—as for example when one undergoes thermal shock, which sounds drastic, but for most people, a cold shower (or even an ice bath) is safe enough.

You can read more about this here:

A Cold Shower A Day Keeps The Doctor Away

Connect with nature

You don’t have to hug a tree, but you do have get to a natural (or at least, natural-seeming) environment once in a while. Simply put, we did not evolve to be in the urban or even suburban settings where most of us spend most of our time. Getting to be around greenery with at least some kind of regularity is hugely beneficial. It doesn’t have to be a national park; a nice garden or local park can suffice, and potted plants at home are better than nothing. Even spending time in virtual reality “nature” is an option:

Effect of Virtual Reality on Stress Reduction and Change of Physiological Parameters Including Heart Rate Variability in People With High Stress: An Open Randomized Crossover Trial

(you can see an example there, of the kind of scenery this study used)

Breathe deeply, and rest deeply

Mindful breathing, and good quality sleep, are very strongly evidence-based approaches to reduce stress, for example:

Practice gratitude to build optimism

Optimism has a huge positive impact on health outcomes, even when other factors (including socioeconomic factors, pre-existing conditions, and general reasons for one person to be more optimistic than another) are controlled for.

Read: Optimism and Cause-Specific Mortality: A Prospective Cohort Study

There are various ways to increase optimism, and practising gratitude is one of them—but that doesn’t necessarily mean abandoning realism, either:

How To Practise (Non-Toxic) Positivity

There are other ways too, though, and Dr. Epel discusses some with her friend and colleague, Dr. Elizabeth Blackburn, here:

TED ideas | Could your thoughts make you age faster? And can we reverse that? | Dr. Elizabeth Blackburn & Dr. Elissa Epel

Want to learn more from Dr. Epel?

We reviewed one of her books, The Telomere Effect, previously. It’s about what we can do to lengthen our telomeres (a key factor in health aging; effectively, being biologically younger). You also might enjoy her newer book, The Stress Prescription, as well as her blog.

Enjoy!

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  • How Intermittent Fasting Reduces Heart Attack Risk (Directly, Not Via Weight Control!)

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    We’ve written before about the benefits of intermittent fasting, such as:

    Intermittent fasting is mostly enjoyed for its metabolic benefits, such as How To Prevent And Reverse Type 2 Diabetes.

    We also covered a very related topic, with intermittent fasting once again being on the suggestions list:

    Improve Your Insulin Sensitivity! ← this is actually more important even that blood sugar control itself, important as that latter is!

    So, how does it work to reduce heart attack risk?

    While intermittent fasting can be used as a weight loss tool (it also doesn’t have to be—it depends on what you eat and what you’re doing in terms of exercise, amongst other factors), this isn’t about that.

    Although it is also worth mentioning that intermittent fasting does reduce the risks associated with diabetes, hypercholesterolemia, cancer, Alzheimer’s, and more, as well as generally improving cardiovascular health by reducing blood pressure, cholesterol, and insulin resistance, amongst other metrics.

    However, this is about platelet aggregation. Or in whole: platelet activation, aggregation, and thrombosis.

    A team of scientists, Dr. Shimo Dai et al., investigated the effects of alternate-day intermittent fasting on platelets and thrombosis, in two quite different, but both important, demographics:

    • Humans with coronary artery disease
    • Mice with the ApoE gene (the Alzheimer’s risk gene)

    Why the mice? Because they wanted to check the level of cerebral ischemia-reperfusion injury (the damage that occurs after a stroke), and no ethics board will let scientists slice up human participants brains at will.

    In both cases, the intermittent fasting group enjoyed protective effects that the control group (ad libitum eating) did not.

    Specifically, reduced platelet activation, as well as reduced platelet aggregation. Just to be clear:

    • Platelet activation = platelets getting deployed
    • Platelet aggregation = platelets sticking together

    Both are required for thrombosis, which occurs when the platelets, having been activated and aggregated (which is their job, for example to stop bleeding in the case of an injury), block one or more blood vessels.

    A healthy level of platelet activation and aggregation rests in the sweet spot wherefrom it can stop bleeding, without stopping blood circulation.

    This was found to be associated with increased levels of indole-3-propionic acid (IPA), which is created by certain gut bacteria (C. sporogenes), who proliferate enthusiastically during intermittent fasting.

    In few words:

    • intermittent fasting triggers the C. sporogenes to proliferate,
    • which increases IPA levels,
    • which reduces platelet activation and aggregation,
    • which reduces the risk of thrombosis,
    • and thus reduces the risk of heart attack.

    We may hypothesize that this may be a reason to not do intermittent fasting if you have a bleeding disorder, and consult your doctor if you’re on blood thinners.

    For everyone else, this is one more thing that makes intermittent fasting a very healthful practice!

    You can find the paper itself here:

    Intermittent fasting inhibits platelet activation and thrombosis through the intestinal metabolite indole-3-propionate

    And here’s a pop-science article that gets more technical than we have, if you’d like a middle-ground in terms of complexity:

    Intermittent fasting cuts heart attack risk by preventing dangerous blood clots

    Want to try intermittent fasting, but it sounds hard?

    Check out this:

    Hack Your Hunger

    Enjoy!

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  • More research shows COVID-19 vaccines are safe for young adults

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    What you need to know

    • Myocarditis, or inflammation of the heart muscle, is most commonly caused by a viral infection like COVID-19, not by vaccination.
    • In line with previous research, a recent CDC study found no association between COVID-19 vaccination and sudden cardiac death in previously healthy young people.
    • A COVID-19 infection is much more likely to cause inflammation of the heart muscle than a COVID-19 vaccine, and those cases are typically more severe.

    Since the approval of the first COVID-19 vaccines, anti-vaccine advocates have raised concerns about heart muscle inflammation, also called myocarditis, after vaccination to suggest that vaccines are unsafe. They’ve also used concerns about myocarditis to spread false claims that vaccines cause sudden deaths, which is not true.

    Research has consistently shown that cases of myocarditis after vaccination are extremely rare and usually mild, and a new study from the CDC found no association between sudden cardiac death and COVID-19 vaccination in young adults.

    Read on to learn more about myocarditis and what the latest research says about COVID-19 vaccine safety.

    What is myocarditis?

    Myocarditis is inflammation of the myocardium, or the middle muscular layer of the heart wall. This inflammation weakens the heart’s ability to pump blood. Symptoms may include fatigue, shortness of breath, chest pain, rapid or irregular heartbeat, and flu-like symptoms.

    Myocarditis may resolve on its own. In rare cases, it may lead to stroke, heart failure, heart attack, or death.

    What causes myocarditis?

    Myocarditis is typically caused by a viral infection like COVID-19. Bacteria, parasites, fungi, chemicals, and certain medications can also cause myocarditis.

    In very rare cases, some people develop myocarditis after receiving a COVID-19 vaccine, but these cases are usually mild and resolve on their own. In contrast, a COVID-19 infection is much more likely to cause myocarditis, and those cases are typically more severe.

    Staying up to date on vaccines reduces your risk of developing myocarditis from a COVID-19 infection.

    Are COVID-19 vaccines safe for young people?

    Yes. COVID-19 vaccines have been rigorously tested and monitored over the past three years and have been determined to be safe for everyone 6 months and older. A recent CDC study found no association between COVID-19 vaccination and sudden cardiac death in previously healthy young adults.

    The benefits of vaccination outweigh any potential risks. Staying up to date on COVID-19 vaccines reduces your risk of severe illness, hospitalization, death, long COVID, and COVID-19-related complications, such as myocarditis.

    The CDC recommends people 65 and older and immunocompromised people receive an additional dose of the updated COVID-19 vaccine this spring—if at least four months have passed since they received a COVID-19 vaccine.

    For more information, talk to your health care provider.

    This article first appeared on Public Good News and is republished here under a Creative Commons license.

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  • Dealing With Back Acne

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s Q&A Day at 10almonds!

    Have a question or a request? We love to hear from you!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small 😎

    ❝Lately I’ve increasingly been getting zits on my back, I don’t think my shower habits have changed at all, is this just an age thing or is there something I can do about it?❞

    Well, we cannot diagnose from afar, so definitely consider seeing a dermatologist if it persists and/or it’s more than a small nuisance to you, but…

    Yes and no, with regard to age.

    Rather, it’s not really about age, but (in most cases, anyway) hormonal fluctuations. That’s why teenagers often get it; it’s also why acne breakouts can occur during pregnancy, and it can happen again in perimenopause, menopause, or in the postmenopause climb-down, due to imbalanced hormones during the change, and while it’s less likely for men undergoing the andropause (the noticeable drop of testosterone levels after a certain age), it can absolutely occur if taking certain androgenic supplements, including simply taking testosterone (or conversely, if taking something to dial down antagonistic hormones). It can also happen if you’re taking something that throws out your free testosterone to DHT ratio.

    See also: Prevalence and Demographics of Truncal Involvement Among Acne Patients: Survey Data and a Review of the Literature

    As for what to do in this case? The usual process is: just wait it out. At some point your hormones will become stable again (nature loves equilibrium, and the body is mostly a self-righting system if given what it needs to do that), and your skin will return to normal. To be clear: the acne occurs because of the change, not necessarily the end place. So whatever hormone levels you have, be they medicated or otherwise, you just need to keep them stable now (assuming the levels are fine; if not, get them fine, and then keep them stable—speak to an endocrinologist for that) in order to come out the other side acne-free.

    However, that’s “the usual process”, and obviously we cannot guarantee it’s not something else. It can also be caused by stress:

    The Impact of Pyschological Stress on Acne ← teehee, a typo made it into the publication title

    …in which case, of course, simply manage your stress (we know, often easier said than done, but the point is, that’s the remedy in this case).

    See also: How To Reduce Chronic Stress

    Diet is not the cause (or cure), but enjoying an anti-inflammatory diet will be beneficial, and consuming inflammatory things, exacerbatory:

    Effects of Diet on Acne and Its Response to Treatment

    Hygiene is also rarely to blame, but it can make a difference, so: do wash gently, wear clean clothes, and wash your bedsheets more often than you think necessary. And about that showering:

    Body Scrubs: Benefits, Risks, and Guidance

    Take care!

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  • Mocktails – by Moira Clark

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    We’ve reviewed books about quitting alcohol before (such as this one), but today’s is not about quitting, so much as about enjoying non-alcoholic drinks; it’s simply a recipe book of zero-alcohol cocktails, or “mocktails”.

    What sets this book apart from many of its kind is that every recipe uses only natural and fresh ingredients, rather than finding in the ingredients list some pre-made store-bought component. Instead, because of its “everything from scratch” approach, this means:

    • Everything is reliably as healthy as the ingredients you use
    • Every recipe’s ingredients can be found easily unless you live in a food desert

    Each well-photographed and well-written recipe also comes with a QR code to see a step-by-step video tutorial (or if you get the ebook version, then a direct link as well).

    Bottom line: this is the perfect mocktail book to have in (and practice with!) before the summer heat sets in.

    Click here to check out Mocktails: A Delicious Collection of Non-Alcoholic Drinks, and get mixing!

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  • HIIT, But Make It HIRT

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    This May HIRT A Bit

    This is Ingrid Clay. She’s a professional athlete, personal trainer, chef*, and science writer.

    *A vegan bodybuilding chef, no less:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    For those who prefer reading…

    This writer does too 😉

    We’ve previously reviewed her book, “Science of HIIT”, and we’re going to be talking a bit about High Intensity Interval Training today.

    If you’d like to know a little more about the woman herself first, then…

    Centr | Meet Ingrid: Your HIIT HIRT trainer

    Yes, that is Centr, as in Chris Hemsworth’s personal training app, where Clay is the resident HIIT & HIRT expert & trainer.

    What’s this HIIT & HIRT?

    HIIT” is High Intensity Interval Training, which we’ve written about before:

    How To Do HIIT (Without Wrecking Your Body)

    Basically, it’s a super-efficient way of working out, that gets better results than working out for longer with other methods, especially because of how it raises the metabolism for a couple of hours after training (this effect is called EPOC, by the way—Excessive Post-exercise Oxygen Consumption), and is a good thing.

    You can read more about the science of it, in the above-linked main feature.

    And HIRT?

    HIRT” is High Intensity Resistance Training, and is resistance training performed with HIIT principles.

    See also: Chris Hemsworth’s Trainer Ingrid Clay Explains HIRT

    An example is doing 10 reps of a resistance exercise (e.g., a dumbbell press) every minute on odd-numbered minutes, and 10 reps of a different resistance exercise (e.g. dumbbell squats) on even-numbered minutes.

    If dumbbells aren’t your thing, it could be resistance bands, or even the floor (press-ups are a resistance exercise!)

    For HIRT that’s not also a cardio exercise, gaps between different exercises can be quite minimal, as we only need to confuse the muscles, not the heart. So, effectively, it becomes a specially focused kind of circuit training!

    If doing planks though, you might want to check out Clay’s troubleshooting guide:

    Expert trainer Ingrid Clay identifies the mistakes many people make when doing the plank, and how to correct them.

    Want more from Clay?

    Here she gives a full 20-minute full-body HIIT HIRT workout:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Enjoy!

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  • The Comfort Zone – by Kristen Butler

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    Are you sitting comfortably? Then we’ll begin. Funny, how being comfortable can be a good starting point, then we are advised “You have to get out of your comfort zone”.

    And yet, when we think of our personal greatest moments in life, they were rarely uncomfortable moments. Why is that?

    Kristen Butler wants us to resolve this paradox, with a reframe:

    The comfort zone? That’s actually the “flow” zone.

    Just as “slow and steady wins the race”, we can—like the proverbial tortoise—take our comfort with us as we go.

    The discomfort zone? That’s the stress zone, the survival zone, the “putting out fires” zone. From the outside, it looks like we’re making a Herculean effort, and perhaps we are, but is it actually so much better than peaceful consistent productivity?

    Butler writes in a way that will be relatable for many, and may be a welcome life-ring if you feel like you’ve been playing catch-up for a while.

    Is she advocating for complacency, then? No, and she discusses this too. That “complacency zone” is really the “burnout zone” after being in the “survival zone” for too long.

    She lays out for us, therefore, a guide for growing in comfort, expanding the comfort zone yes, but by securely pushing it from the inside, not by making a mad dash out and hoping it follows us.

    Bottom line: if you’ve been (perhaps quietly) uncomfortable for a little too long for comfort, this book can reframe your approach to get you to a position of sustainable, stress-free growth.

    Click here to check out The Comfort Zone, and start building yours!

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    Learn to Age Gracefully

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