Retinoids: Retinol vs Retinal vs Retinoic Acid vs..?

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It’s Q&A Day at 10almonds!

Have a question or a request? We love to hear from you!

In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

So, no question/request too big or small 😎

❝I’m confused about retinol, retinal, retinoin, retinoids, etc, and of course every product claims to be the best, what’s the actual science on it?❞

Before we get into these skincare products, let’s first note that for most people, what’s best for the skin is good sleep and hydration, a plants-centric whole foods diet, and good stress management:

See for example: Of Brains And Breakouts: The Brain Skin Doctor

However, the world of potions and lotions can be an alluring one, and there is some merit there too. So, in a nutshell:

  • Retinoids are the overall class of chemicals, and not a specific type
    • Retinoic acid is the strongest form of this chemical and is prescription-controlled in most places
      • Retinoin” is probably tretinoin (all-trans retinoic acid) with the “t” having fallen off; we can only find it being used as a product name, not an actual substance
    • Retinal, when it’s not an adjective referring to the retina (the part of the eye that receives refocussed light) and is instead a noun, is a less potent retinoid than the prescription-only kinds, but still stronger than retinol
    • Retinol is a much less potent form, and is the most widely found in skincare products

All of them work the same way; it is only how serious they are about it that differs.

The mechanism of action is that they speed up the turnover (shedding cycle) of skin, so that cells are replaced sooner. As with any non-cancerous human tissue, this means that the tissue itself (in this case, your skin) will be biologically younger than if it had been replaced later.

The downside, of course, of this is that—while trying to make your skin healthier and more beautiful—the first thing that will happen is skin shedding. Depending on the retinoid type, dose, and the health of your skin to start with, this may mean anything from needing to exfoliate in the morning, to having to go to hospital with what looks like the world’s worst sunburn. For this reason, it is recommended to start with weaker products and lower doses, and work up carefully.

A note on doses: the recommended doses for these products are always truly tiny, like “use a pea-sized amount of this 0.05% serum on your face”. Take them seriously until you’re absolutely sure from experience that your skin can handle more.

Also, a tip: wear gloves when you apply any of the above products. This is because your fingers are also covered in skin, and if you don’t use gloves, then half the product that you intended for your face will be absorbed into your fingers instead. On the bright side, you’ll have beautifully rejuvenated fingertips, though.

You can learn more about the science of retinoids here, in our article about tretinoin, the usually prescription-only form of retinoic acid:

Tretinoin: Undo The Sun’s Damage To Your Skin

Want to try some?

We don’t sell it, but here for your convenience is an example product of retinal (stronger than retinol) on Amazon 😎

Take care!

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  • Tomatoes vs Carrots – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing tomatoes to carrots, we picked the carrots.

    Why?

    Both known for being vitamin-A heavyweights, there is nevertheless a clear winner:

    In terms of macros, carrots have a little over 2x the carbs, and/but also a little over 2x the fiber, so we consider category this a win for carrots.

    In the category of vitamins, tomatoes have more vitamin C, while carrots have more of vitamins A, B1, B2, B3, B5, B6, B9, E, K, and choline. And about that vitamin A specifically: carrots have over 20x the vitamin A of tomatoes. An easy win for carrots here!

    When it comes to minerals, tomatoes have a little more copper, while carrots have more calcium, iron, magnesium, manganese, phosphorus, potassium, selenium, and zinc. Another clear win for carrots.

    Looking at polyphenols, carrots are good but tomatoes have more, including a good healthy dose of quercetin; they also have more lycopene, not technically a polyphenol by virtue of its chemical structure (it’s a carotenoid), but a powerful phytochemical nonetheless (and much more prevalent in sun-dried tomatoes, in any case, which is not what we were looking at today—perhaps another day we’ll do sun-dried tomatoes and carrots head-to-head!).

    Still, a) carrots are not short of carotenoids either (including lycopene), and b) we don’t think the moderate win on polyphenols is enough to outdo carrots having won all the other categories.

    All in all, carrots win the day, but of course, do enjoy either or both; diversity is good!

    Want to learn more?

    You might like to read:

    Lycopene’s Benefits For The Gut, Heart, Brain, & More

    Enjoy!

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  • Myofascial Training – by Ester Albini

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Fascia is an oft-forgotten part of the body—if something that is so ubiquitous and varied can be described as a single part. And yet, it arguably is—precisely because it is the connective tissue that holds everything else together, so by its nature, it’s ultimately a one-piece thing.

    This “one-piece thing” is responsible for permitting us movement, and is also responsible for restricting our movement. As such, when it comes to mobility, we can stretch our muscles all day long and it won’t mean a thing if our fascia is stiff. And notably, fascia has a much slower turnover time (in terms of how quickly the body replaces it) than muscle, so fascia is almost always going to be the limiting factor.

    Pilates instructor (with many certifications) Albini gives the reader the tools to loosen up that limiting factor. It’ll take time and consistency (it takes the body around 18 months to fully rebuild fascia, so that’s the timeframe for an ultimate “job done” to then just be maintained), but there are also some results to be enjoyed immediately, by virtue of myofascial release

    In style, the book is half textbook, half workbook. She explains a lot of the anatomy and physiology of fascia (and does so very well). This book is, in this reviewer’s opinion, better than the usual go-to professional guidebook to fascia (i.e., for physiotherapists etc) that costs more than twice the price and is half as clear (the other book’s diagrams are unnecessarily abstract, the photos fuzzy, and the prose tedious). This book, in contrast, has very clear diagrams, hundreds of high-quality color photos, and excellent explanations that are aimed at the layperson, and/but aren’t afraid to get technical either; she just explains the technicalities well too.

    The workbook side of things is a vast array of exercises to do, including for specific issues and to combat various lifestyle problems, as well as to just support general health and more mobility than most people think is possible for them.

    Bottom line: if you’d like better mobility and have been neglecting your fascia (or have been a bit confused by it), this book is going to be your new best friend.

    Click there to check out Myofascial Training, and free your body’s movements!

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  • Professional-Style Dental Cleaning At Home?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    You know the scene: your dentist is rummaging around inside your mouth with an implement that looks like a medieval torture device; you wince at a sudden sharp pain, only to be told “if you flossed, you wouldn’t be bleeding now”.

    For most of us, going to the dentist isn’t near the top of our “favorite things to do” list, but it is of course a necessity of (healthy) life.

    So, what can we do to minimize suffering in the dentist’s chair?

    First, the basics

    Of course, good oral hygiene is the absolute baseline, but with so many choices out there, which is best? We examined an array of options in this three-part series:

    1. Toothpastes & Mouthwashes: Which Help And Which Harm?
    2. Flossing Without Flossing?
    3. Less Common Oral Hygiene Options ← we recommend the miswak! Not only does it clean the teeth as well as or better than traditional brushing, but also it changes the composition of saliva to improve the oral microbiome, effectively turning your saliva into a biological mouthwash that kills unwanted microbes and is comfortable for the ones that should be there.

    In fact, caring for the composition of one’s saliva, and thus one’s oral microbiome, is so important that we did a main feature on that, a little later:

    Make Your Saliva Better For Your Teeth ← this is especially important if you take any meds that affect the composition of your saliva (scroll down to the table of meds). Your medications’ leaflets won’t tell you that it does that directly, but they will list “dry mouth” as one of the potential side effects (and you’ll probably know if you have a medication that gives you a dry mouth).

    Next, level up

    For this one, we’ll drop some links to some videos we’ve featured (for those who prefer text, worry not, your faithful writer has added text-based overviews):

    Now, that last one sounds slightly more exciting than it is—it is about using chemical processes to gradually lessen the tartar over time, with a six-month timeframe.

    So, what if you want to do one better than that?

    Finally… Buckle up, this one’s fun

    Ok, so “fun” and “dental care” don’t usually go hand-in-hand, and maybe your sense of fun differs from this writer’s, but hey. The thing is, we’re going to get hands-on with dental tools.

    Specifically, these dental tools:

    👆 these are literally the tools this writer has; if you look in the specula (the round mirror bits), you can see the reflection of the fluffy gray bathrobe I was wearing when I took the picture!

    You can get tools like these easily online; here’s an example product on Amazon; do also shop around of course, and we recommend checking the reviews to ensure good quality.

    Writer’s story on why I have these: once upon a time, a wisdom tooth came through at 45°, ploughing through the molar next to it, which then needed removing.

    However, my teeth have the interesting anatomical quirk that I have hooked/barbed roots, which does not make tooth extraction easy; it had to come out sidewise, and the process was somewhat bungled by an inexperienced dental surgeon.

    When the anesthetic wore off, it was the most pain I’ve ever been in in my life.

    After that, I wasn’t a very regular returner to the dentist, and in 2013, I fell into a very deep depression for unrelated reasons, and during that period, I got some plaque/tartar buildup on some of my teeth due to lack of care, that then just stayed until I decided to take care of it more recently, which I am happy to say, I’ve now done (my teeth are the happiest and healthiest they’ve ever been), and I’m going to share how, with you.

    So, here’s how to do it… First, you’ll need those tools, of course.

    You will also want a good quality backlit magnifying mirror. Again, here’s an example product on Amazon ← this is the exact kind this writer has, and it’s very good.

    You may be thinking: “wait a minute, this is scary, those are dangerous and I’m not a dentist!”

    If so, then a few quick things to bear in mind:

    • If you’re not comfortable doing it, don’t do it. As ever, our medical/legal disclaimer applies, and we share information for your interest only, and not as an exhortation to take any particular action. By all means confer with your dentist, too, and see whether they support the idea.
    • These things do look scarier than they are once you get used to them. Do you use metal silverware when eating? Technically you could stab yourself with a fork any time, or damage your teeth with it, but when was the last time you did that?
    • With regard to manual dexterity, if you have the manual dexterity required to paint your nails, floss your teeth, sew by hand, or write with a pen, then you have the manual dexterity to do this, too.

    Now, about the tools:

    • Speculum / magnifying speculum: the one with the mirror. This is useful for looking at the backs of teeth.
    • Tweezers: the one with the gold grip in the photo above. You probably won’t need to use these, but we’re sure you know how to use tweezers in general.
    • Dental explorer: the one with the big wicked-looking hook on one end, and a tiny (almost invisible in the photo) hook on the other end. This is for examining cavities, not for manipulating things. Best leave that to your dentist if you have cavities.
    • Dental pick: this is the one to the right of the dental explorer, and it is for cleaning in the crevices between teeth. One end is quite blunt; the other is pointier, and you can choose which end to use depending on what fits into the shape of the crevice between your teeth.
    • Dental scraper: this is the one with chisel ends. One end curves very slightly to the left, the other, very slightly to the right. This is for ergonomics depending on which hand you’re using, and which side you’re scraping (you’ll become very aware that your teeth, even if they look straight, curve very slightly at the edges.

    You’ll be using these last two for the actual tartar removal, selecting the tool appropriate to cleaning the flat surface of a tooth, or the crevice where the teeth meet (not like flossing! That part, yes, but under no circumstances is this thing going all the way through to the other side, it’s just for getting into to nook that the scraper can’t so easily clean, that’s all).

    A word on using metal against your teeth: a scary prospect, initially! However…

    While steel is indeed harder than the enamel of your teeth, the enamel of your teeth is much harder than the plaque/tartar/calculus that you will be removing. Therefore, the technique to use is very gently scrape, starting as gently as humanly possible until you get a feel for it.

    Unlike the dentist, you will have an advantage here in that you have biofeedback, and bone conduction of the sounds in your mouth, so you can exercise much more restraint than your dentist can. With the correct minimum of pressure, the tool should glide smoothly down enamel, but when it’s scraping tartar, it should make a very fine sandpapery noise.

    This is why “or write with a pen” was one of the skills we mentioned earlier; it’s the same thing; you don’t press with a pen so hard that it goes through the paper, so don’t press so hard with the tool that it damages your enamel, that’s all.

    Because of the differential in hardness between the tartar and the enamel, it’s really very easy to remove the tartar without harming the enamel, provided one is gentle.

    Final word of warning; we’ll repeat: If you’re not comfortable doing it, don’t do it. As ever, our medical/legal disclaimer applies, and we share information for your interest only, and not as an exhortation to take any particular action. By all means confer with your dentist, too, and see whether they support the idea.

    Also, while this kind of cleaning can be done safely at home, we recommend against doing anything more complicated than that.

    See for example: Can You Repair Your Own Teeth At Home? ← the short answer is “no”, or not beyond tooth remineralization, anyway, and kits that say otherwise are potentially misleading, or stop-gap solutions at best.

    One last time: always consult with a professional and get their advice (ours is not advice; it’s just information).

    Take care!

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  • The Many Health Benefits Of Garlic

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    The Many Health Benefits of Garlic

    We’re quite confident you already know what garlic is, so we’re going to leap straight in there with some science today:

    First, let’s talk about allicin

    Allicin is a compound in garlic that gives most of its health benefits. A downside of allicin is that it’s not very stable, so what this means is:

    • Garlic is best fresh—allicin breaks down soon after garlic is cut/crushed
      • So while doing the paperwork isn’t fun, buying it as bulbs is better than buying it as granules or similar
    • Allicin also breaks down somewhat in cooking, so raw garlic is best
      • Our philosophy is: still use it in cooking as well; just use more!
    • Supplements (capsule form etc) use typically use extracts and potency varies (from not great to actually very good)

    Read more about that:

    Now, let’s talk benefits…

    Benefits to heart health

    Garlic has been found to be as effective as the drug Atenolol at reducing blood pressure:

    Effects of Allium sativum (garlic) on systolic and diastolic blood pressure in patients with essential hypertension

    It also lowers LDL (bad cholesterol):

    Lipid-lowering effects of time-released garlic powder tablets in double-blinded placebo-controlled randomized study

    Benefits to the gut

    We weren’t even looking for this, but as it turns out, as an add-on to the heart benefits…

    Garlic lowers blood pressure in hypertensive subjects, improves arterial stiffness and gut microbiota: A review and meta-analysis

    Benefits to the immune system

    Whether against the common cold or bringing out the heavy guns, garlic is a booster:

    Benefits to the youthfulness of body and brain

    Garlic is high in antioxidants that, by virtue of reducing oxidative stress, help slow aging. This effect, combined with the cholesterol and blood pressure benefits, means it may also reduce the risk of Alzheimer’s and other forms of dementia:

    There are more benefits too…

    That’s all we have time to dive into study-wise today, but for the visually-inclined, here are yet more benefits to garlic (at a rate of 3–4 cloves per day):

    An incredible awesome recipe using lots of garlic:

    • Take small potatoes (still in their skins), cut in half
    • Add enough peeled cloves of garlic so that you have perhaps a 1:10 ratio of garlic to potato by mass
    • Boil (pressure-cooking is ideal) until soft, and drain
    • Keeping them in the pan, add a lashing of olive oil, and any additional seasonings per your preference (consider black pepper, rosemary, thyme, parsley)
    • Put a lid on the pan, and holding it closed, shake the pan vigorously
      • Note: if you didn’t leave the skins on, or you chopped much larger potatoes smaller instead of cutting in half, the potatoes will break up into a rough mash now. This is actually also fine and still tastes (and honestly, looks) great, but it is different, so just be aware, so that you get the outcome you want.
    • The garlic, which—unlike the potatoes—didn’t have a skin to hold it together, will now have melted over the potatoes like butter

    You can serve like this (it’s delicious already) or finish up in the oven or air-fryer or under the grill, if you prefer a roasted style dish (an amazing option too).

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  • Women take more antidepressants after divorce than men but that doesn’t mean they’re more depressed

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Research out today from Finland suggests women may find it harder to adjust to later-life divorce and break-ups than men.

    The study used population data from 229,000 Finns aged 50 to 70 who had undergone divorce, relationship break-up or bereavement and tracked their use of antidepressants before and after their relationship ended.

    They found antidepressant use increased in the four years leading to the relationship dissolution in both genders, with women experiencing a more significant increase.

    But it’s too simplistic to say women experience poorer mental health or tend to be less happy after divorce than men.

    Remind me, how common is divorce?

    Just under 50,000 divorces are granted each year in Australia. This has slowly declined since the 1990s.

    More couple are choosing to co-habitate, instead of marry, and the majority of couples live together prior to marriage. Divorce statistics don’t include separations of cohabiting couples, even though they are more likely than married couples to separate.

    Those who divorce are doing so later in life, often after their children grow up. The median age of divorce increased from 45.9 in 2021 to 46.7 in 2022 for men and from 43.0 to 43.7 for women.

    The trend of late divorces also reflects people deciding to marry later in life. The median duration from marriage to divorce in 2022 was around 12.8 years and has remained fairly constant over the past decade.

    Why do couples get divorced?

    Changes in social attitudes towards marriage and relationships mean divorce is now more accepted. People are opting not to be in unhappy marriages, even if there are children involved.

    Instead, they’re turning the focus on marriage quality. This is particularly true for women who have established a career and are financially autonomous.

    Similarly, my research shows it’s particularly important for people to feel their relationship expectations can be fulfilled long term. In addition to relationship quality, participants reported needing trust, open communication, safety and acceptance from their partners.

    Grey divorce” (divorce at age 50 and older) is becoming increasingly common in Western countries, particularly among high-income populations. While factors such as an empty nest, retirement, or poor health are commonly cited predictors of later-in-life divorce, research shows older couples divorce for the same reasons as younger couples.

    What did the new study find?

    The study tracked antidepressant use in Finns aged 50 to 70 for four years before their relationship breakdown and four years after.

    They found antidepressant use increased in the four years leading to the relationship break-up in both genders. The proportion of women taking antidepressants in the lead up to divorce increased by 7%, compared with 5% for men. For de facto separation antidepressant use increased by 6% for women and 3.2% for men.

    Within a year of the break-up, antidepressant use fell back to the level it was 12 months before the break-up. It subsequently remained at that level among the men.

    But it was a different story for women. Their use tailed off only slightly immediately after the relationship breakdown but increased again from the first year onwards.

    Woman sits at the beach
    Women’s antidepressant use increased again.
    sk/Unsplash

    The researchers also looked at antidepressant use after re-partnering. There was a decline in the use of antidepressants for men and women after starting a new relationship. But this decline was short-lived for women.

    But there’s more to the story

    Although this data alone suggest women may find it harder to adjust to later-life divorce and break-ups than men, it’s important to note some nuances in the interpretation of this data.

    For instance, data suggesting women experience depression more often than men is generally based on the rate of diagnoses and antidepressant use, which does not account for undiagnosed and unmedicated people.

    Women are generally more likely to access medical services and thus receive treatment. This is also the case in Australia, where in 2020–2022, 21.6% of women saw a health professional for their mental health, compared with only 12.9% of men.

    Why women might struggle more after separating

    Nevertheless, relationship dissolution can have a significant impact on people’s mental health. This is particularly the case for women with young children and older women.

    So what factors might explain why women might experience greater difficulties after divorce later in life?

    Research investigating the financial consequences of grey divorce in men and women showed women experienced a 45% decline in their standard of living (measured by an income-to-needs ratio), whereas men’s dropped by just 21%. These declines persisted over time for men, and only reversed for women following re-partnering.

    Another qualitative study investigating the lived experiences of heterosexual couples post-grey divorce identified financial worries as a common theme between female participants.

    A female research participant (age 68) said:

    [I am most worried about] the money, [and] what I’m going to do when the little bit of money I have runs out […] I have just enough money to live. And, that’s it, [and if] anything happens I’m up a creek. And Medicare is incredibly expensive […] My biggest expense is medicine.

    Another factor was loneliness. One male research participant (age 54) described he preferred living with his ex-wife, despite not getting along with her, than being by himself:

    It was still [good] knowing that [the] person was there, and now that’s gone.

    Other major complications of later-life divorce are possible issues with inheritance rights and next-of-kin relationships for medical decision-making.

    Separation can be positive

    For some people, divorce or separation can lead to increased happiness and feeling more independent.

    And the mental health impact and emotional distress of a relationship dissolution is something that can be counterattacked with resilience. Resilience to dramatic events built from life experience means older adults often do respond better to emotional distress and might be able to adjust better to divorce than their younger counterparts.The Conversation

    Raquel Peel, Adjunct Senior Lecturer, University of Southern Queensland and Senior Lecturer, RMIT University

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • To-Do List Formula – by Damon Zahariades

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    The first part of this book is given to reviewing popular to-do list methods that are already widely “out there”. This treatment is practical and exploratory, looking at the pros and cons of each.

    The second part of the book is more Zahariades’ own method, taking what he sees as the best of each, plus some tricks and practices of his own. With these, he builds (and shares!) his optimized system.

    You may be wondering what you, dear reader, can expect to get out of this book. Well, that depends on where you’re coming from:

    Are you new to approaching your general to-dos with a system more organized than post-it notes on your fridge? If so, this will be a great initial introduction to many systems.

    Or are you, perhaps, a veteran of GTD, ToDoist, assorted Pomodoro-based systems, and more? Do you do/delegate/defer/ditch tasks more deftly and dextrously than Serena Williams despatches tennis balls?

    If so, what you’re more likely to gain here is a fresh perspective on old ideas, and maybe a trick or two you didn’t know before. At the very least, a boost to your motivation, getting you fired up for doing what you know best again.

    All in all, a very respectable book for anyone’s to-read list!

    Pick Up Your Copy of Zahariades’ To-Do List Formula on Amazon Today!

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