Retinoids: Retinol vs Retinal vs Retinoic Acid vs..?

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It’s Q&A Day at 10almonds!

Have a question or a request? We love to hear from you!

In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

So, no question/request too big or small 😎

❝I’m confused about retinol, retinal, retinoin, retinoids, etc, and of course every product claims to be the best, what’s the actual science on it?❞

Before we get into these skincare products, let’s first note that for most people, what’s best for the skin is good sleep and hydration, a plants-centric whole foods diet, and good stress management:

See for example: Of Brains And Breakouts: The Brain Skin Doctor

However, the world of potions and lotions can be an alluring one, and there is some merit there too. So, in a nutshell:

  • Retinoids are the overall class of chemicals, and not a specific type
    • Retinoic acid is the strongest form of this chemical and is prescription-controlled in most places
      • Retinoin” is probably tretinoin (all-trans retinoic acid) with the “t” having falling off; we can only find it being used as a product name, not an actual substance
    • Retinal, when it’s not an adjective referring to the retina (the part of the eye that receives refocussed light) and is instead a noun, is a less potent retinoid than the prescription-only kinds, but still stronger than retinol
    • Retinol is a much less potent form, and is the most widely found in skincare products

All of them work the same way; it is only how serious they are about it that differs.

The mechanism of action is that they speed up the turnover (shedding cycle) of skin, so that cells are replaced sooner. As with any non-cancerous human tissue, this means that the tissue itself (in this case, your skin) will be biologically younger than if it had been replaced later.

The downside, of course, of this is that—while trying to make your skin healthier and more beautiful—the first thing that will happen is skin shedding. Depending on the retinoid type, dose, and the health of your skin to start with, this may mean anything from needing to exfoliate in the morning, to having to go to hospital with what looks like the world’s worst sunburn. For this reason, it is recommended to start with weaker products and lower doses, and work up carefully.

A note on doses: the recommended doses for these products are always truly tiny, like “use a pea-sized amount of this 0.05% serum on your face”. Take them seriously until you’re absolutely sure from experience that your skin can handle more.

Also, a tip: wear gloves when you apply any of the above products. This is because your fingers are also covered in skin, and if you don’t use gloves, then half the product that you intended for your face will be absorbed into your fingers instead.

You can learn more about the science of retinoids here, in our article about tretinoin, the usually prescription-only form of retinoic acid:

Tretinoin: Undo The Sun’s Damage To Your Skin

Want to try some?

We don’t sell it, but here for your convenience is an example product of retinal (stronger than retinol) on Amazon 😎

Take care!

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  • Peas vs Broad Beans – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing peas to broad beans, we picked the peas.

    Why?

    Both are great of course, but…

    Looking at the macros to start with, peas have more protein and more fiber. The differences aren’t huge, but they are clear.

    In terms of vitamins, peas have more of vitamins A, B1, B2, B3, B5, B6, B9, E, K, and choline (some with very large margins, some with small), while broad beans contain a little more vitamin C (the margin is quite narrow though).

    When it comes to minerals, peas have more calcium, copper, iron, magnesium, manganese, phosphorus, potassium, selenium, and zinc, while broad beans have more sodium. So this category wasn’t close.

    Adding up the win from each of the categories makes for a clear triple-win for peas.

    Easy-peasy!

    Want to learn more?

    You might like to read:

    Dr. Greger’s Daily Dozen

    Take care!

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  • Decoding Hormone Balancing in Ads

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s Q&A Time!

    This is the bit whereby each week, we respond to subscriber questions/requests/etc

    Have something you’d like to ask us, or ask us to look into? Hit reply to any of our emails, or use the feedback widget at the bottom, and a Real Human™ will be glad to read it!

    Q: As to specific health topics, I would love to see someone address all these Instagram ads targeted to women that claim “You only need to ‘balance your hormones’ to lose weight, get ripped, etc.” What does this mean? Which hormones are they all talking about? They all seem to be selling a workout program and/or supplements or something similar, as they are ads, after all. Is there any science behind this stuff or is it mostly hot air, as I suspect?

    Thank you for asking this, as your question prompted yesterday’s main feature, What Does “Balancing Your Hormones” Even Mean?

    That’s a great suggestion also about addressing ads (and goes for health-related things in general, not just hormonal stuff) and examining their claims, what they mean, how they work (if they work!), and what’s “technically true but may be misleading* cause confusion”

    *We don’t want companies to sue us, of course.

    Only, we’re going to need your help for this one, subscribers!

    See, here at 10almonds we practice what we preach. We limit screen time, we focus on our work when working, and simply put, we don’t see as many ads as our thousands of subscribers do. Also, ads tend to be targeted to the individual, and often vary from country to country, so chances are good that we’re not seeing the same ads that you’re seeing.

    So, how about we pull together as a bit of a 10almonds community project?

    • Step 1: add our email address to your contacts list, if you haven’t already
    • Step 2: When you see an ad you’re curious about, select “share” (there is usually an option to share ads, but if not, feel free to screenshot or such)
    • Step 3: Send the ad to us by email

    We’ll do the rest! Whenever we have enough ads to review, we’ll do a special on the topic.

    We will categorically not be able to do this without you, so please do join in—Many thanks in advance!

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  • Grains: Bread Of Life, Or Cereal Killer?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Going Against The Grain?

    In Wednesday’s newsletter, we asked you for your health-related opinion of grains (aside from any gluten-specific concerns), and got the above-depicted, below-described, set of responses:

    • About 69% said “They are an important cornerstone of a healthy balanced diet”
    • About 22% said “They can be enjoyed in moderation, but watch out”
    • About 8% said “They are terrible health-drainers that will kill us”

    So, what does the science say?

    They are terrible health-drainers that will kill us: True or False?

    True or False depending on the manner of their consumption!

    There is a big difference between the average pizza base and a bowl of oats, for instance. Or rather, there are a lot of differences, but what’s most critical here?

    The key is: refined and ultraprocessed grains are so inferior to whole grains as to be actively negative for health in most cases for most people most of the time.

    But! It’s not because processing is ontologically evil (in reality: some processed foods are healthy, and some unprocessed foods are poisonous). although it is a very good general rule of thumb.

    So, we need to understand the “why” behind the “key” that we just gave above, and that’s mostly about the resultant glycemic index and associated metrics (glycemic load, insulin index, etc).

    In the case of refined and ultraprocessed grains, our body gains sugar faster than it can process it, and stores it wherever and however it can, like someone who has just realised that they will be entertaining a houseguest in 10 minutes and must tidy up super-rapidly by hiding things wherever they’ll fit.

    And when the body tries to do this with sugar from refined grains, the result is very bad for multiple organs (most notably the liver, but the pancreas takes quite a hit too) which in turn causes damage elsewhere in the body, not to mention that we now have urgently-produced fat stored in unfortunate places like our liver and abdominal cavity when it should have gone to subcutaneous fat stores instead.

    In contrast, whole grains come with fiber that slows down the absorption of the sugars, such that the body can deal with them in an ideal fashion, which usually means:

    • using them immediately, or
    • storing them as muscle glycogen, or
    • storing them as subcutaneous fat

    👆 that’s an oversimplification, but we only have so much room here.

    For more on this, see:

    Glycemic Index vs Glycemic Load vs Insulin Index

    And for why this matters, see:

    Which Sugars Are Healthier, And Which Are Just The Same?

    And for fixing it, see:

    How To Unfatty A Fatty Liver

    They can be enjoyed in moderation, but watch out: True or False?

    Technically True but functionally False:

    • Technically true: “in moderation” is doing a lot of heavy lifting here. One person’s “moderation” may be another person’s “abstemiousness” or “gluttony”.
    • Functionally false: while of course extreme consumption of pretty much anything is going to be bad, unless you are Cereals Georg eating 10,000 cereals each day and being a statistical outlier, the issue is not the quantity so much as the quality.

    Quality, we discussed above—and that is, as we say, paramount. As for quantity however, you might want to know a baseline for “getting enough”, so…

    They are an important cornerstone of a healthy balanced diet: True or False?

    True! This one’s quite straightforward.

    3 servings (each being 90g, or about ½ cup) of whole grains per day is associated with a 22% reduction in risk of heart disease, 5% reduction in all-cause mortality, and a lot of benefits across a lot of disease risks:

    ❝This meta-analysis provides further evidence that whole grain intake is associated with a reduced risk of coronary heart disease, cardiovascular disease, and total cancer, and mortality from all causes, respiratory diseases, infectious diseases, diabetes, and all non-cardiovascular, non-cancer causes.

    These findings support dietary guidelines that recommend increased intake of whole grain to reduce the risk of chronic diseases and premature mortality.❞

    ~ Dr. Dagfinn Aune et al.

    Read in full: Whole grain consumption and risk of cardiovascular disease, cancer, and all cause and cause specific mortality: systematic review and dose-response meta-analysis of prospective studies

    We’d like to give a lot more sources for the same findings, as well as papers for all the individual claims, but frankly, there are so many that there isn’t room. Suffice it to say, this is neither controversial nor uncertain; these benefits are well-established.

    Here’s a very informative pop-science article, that also covers some of the things we discussed earlier (it shows what happens during refinement of grains) before getting on to recommendations and more citations for claims than we can fit here:

    Harvard School Of Public Health | Whole Grains

    “That’s all great, but what if I am concerned about gluten?”

    There certainly are reasons you might be, be it because of a sensitivity, allergy, or just because perhaps you’d like to know more.

    Let’s first mention: not all grains contain gluten, so it’s perfectly possible to enjoy naturally gluten-free grains (such as oats and rice) as well as gluten-free pseudocereals, which are not actually grains but do the same job in culinary and nutritional terms (such as quinoa and buckwheat, despite the latter’s name).

    Finally, if you’d like to know more about gluten’s health considerations, then check out our previous mythbusting special:

    Gluten: What’s The Truth?

    Enjoy!

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  • No Equipment Muscle Gain Routine for Ages 50+

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    Sarcopenia, the loss of muscle mass commonly associated with aging, can be a big problem as it leaves us vulnerable to injury (and also isn’t great for the metabolism—keeping adequate muscle mass ensures keeping the metabolism ticking over nicely). Will Harlow, over-50s specialist physiotherapist, is here to share a routine that works without weights:

    Where it counts

    There’s a fair amount of emphasis here on the lower body and core. That’s because in practical terms, this is what matters more for our health than having bulging biceps:

    • First exercise: donkey calf raises to build strength in the calves using a chair.
    • Second exercise: single-leg elevated lunge to work the quads and glutes, using a step or books for elevation.
    • Third exercise: slow sit-to-stand for quads, glutes, and core strength, focusing on a slow descent.
    • Fourth exercise: wall press-up to strengthen the chest, shoulders, and arms, with a variation using towels for increased resistance.
    • Final exercise: shoulder raises using bottles or similar weights to target the shoulders and rotator cuffs.

    Ok, so that last one was a slight cheat on his part as it does require grabbing a weight, but it’s not specialist equipment at least, and can just be something you grabbed at home. It’s also the least important of the five exercises, and can be skipped if necessary.

    For more on all of these plus visual demonstrations, enjoy:

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    Take care!

    Don’t Forget…

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    Learn to Age Gracefully

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  • Getting Flexible, Starting As An Adult: How Long Does It Really Take?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Aleks Brzezinska didn’t start stretching until she was 21, and here’s what she found:

    We’ll not stretch the truth

    A lot of stretching programs will claim “do the splits in 30 days” or similar, and while this may occasionally be true, usually it’ll take longer.

    Brzezinska started stretching seriously when she was 21, and made significant flexibility gains between the ages of 21 and 23 with consistent practice. Since then, she’s just maintained her flexibility.

    There are facts that affect progress significantly, such as:

    • Anatomy: body structure, age, and joint flexibility do influence flexibility; starting younger and/or having hypermobile joints does make it easier.
    • Consistency: regular practice (2–3 times a week) is crucial, but avoid overdoing it, especially when sore.
    • Lifestyle: weightlifting, running, and similar activities can tighten muscles, making flexibility harder to achieve.
    • Hydration: staying hydrated is important for muscle flexibility.

    She also recommends incorporating a variety of different stretching types, rather than just one method, for example passive stretching, active stretching, Proprioceptive Neuromuscular Facilitation (PNF) stretching, and mobility work.

    For more on each of these, enjoy:

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    Take care!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:

  • 7 Ways To Boost Mitochondrial Health To Fight Disease

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Fatigue and a general lack of energy can be symptoms of many things, and for most of them, looking after our mitochondrial health can at least help, if not outright fix the issue.

    The Seven Ways

    Dr. Jonas Kuene suggests that we…

    • Enjoy a good diet: especially, limiting simple sugars, reducing overall carbohydrate intake, and swapping seed oils for healthier oils like avocado oil and olive oil.
    • Take supplements: including coenzyme Q10, alpha-lipoic acid, and vitamins
    • Decrease exposure to toxins: limit alcohol consumption (10almonds tip: limit it to zero if you can), avoid foods that are likely high in heavy metals or pesticides, and check you’re not being overmedicated (there can be a bit of a “meds creep” over time if left unchecked, so it’s good to periodically do a meds review in case something is no longer needed)
    • Practice intermittent fasting: Dr. Kuene suggests a modest 16–18 hours fast per week; doing so daily is generally considered good advice, for those for whom this is a reasonable option
    • Build muscle: exercise in general is good for mitochondria, but body composition itself counts for a lot too
    • Sleep: aiming for 7–9 hours, and if that’s not possible at night, add a nap during the day to make up the lost time
    • Get near-infrared radiation: from the sun, and/or made-for-purpose IR health devices.

    For more info on these (including the referenced science), enjoy:

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    Take care!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails: