Resveratrol & Healthy Aging
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Resveratrol & Healthy Aging
Resveratrol is the compound found in red grapes, and thus in red wine, that have resulted in red wine being sometimes touted as a heart-healthy drink.
However, at the levels contained in red wine, you’d need to drink 100–1000 glasses of wine per day (depending on the wine) to get the dose of resveratrol that was associated with heart health benefits in mouse studies.
Which also means: if you are not a mouse, you might need to drink even more than that!
Further reading: can we drink to good health?
Resveratrol supplementation
Happily, resveratrol supplements exist. But what does resveratrol do?
It lowers blood pressure:
Effect of resveratrol on blood pressure: a meta-analysis of randomized controlled trials
It improves blood lipid levels:
It improves insulin sensitivity:
It has neuroprotective effects too:
Resveratrol promotes clearance of Alzheimer’s disease amyloid-beta peptides
Is it safe?
For most people, it is generally recognized as safe. However, if you are on blood-thinners or otherwise have a bleeding disorder, you might want to skip it:
Antiplatelet activity of synthetic and natural resveratrol in red wine
You also might want to check with your pharmacist/doctor, if you’re on blood pressure meds, anxiety meds, or immunosuppressants, as it can increase the amount of these drugs that will then stay in your system:
Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study
And as ever, of course, if unsure just check with your pharmacist/doctor, to be on the safe side.
Where to get it?
We don’t sell it, but here’s an example product on Amazon for your convenience
Enjoy!
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How Jumping Rope Changes The Human Body
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Most popularly enjoyed by professional boxers and six-year-old girls, jumping rope is one of the most metabolism-boosting exercises around:
Just a hop, skip, and a jump away from good health
Maybe you haven’t tried it since your age was in single digits, so, if you do…
What benefits can you expect?
- Improves cardiovascular fitness, equivalent to 30 minutes of running with just 10 minutes of jumping.
- Increases bone density and boosts immunity by aiding the lymphatic system.
- Enhances explosiveness in the lower body, agility, and stamina.
- Improves shoulder endurance, coordination, and spatial awareness.
What kind of rope is best for you?
- Beginner ropes: licorice ropes (nylon/vinyl), beaded ropes for rhythm and durability.
- Advanced ropes: speed ropes (denser, faster materials) for higher speeds and more difficult skills.
- Weighted ropes: build upper body muscles (forearms, shoulders, chest, back).
What length should you get?
- Recommended rope length varies by height (8 ft for 5’0″–5’4″, 9 ft for 5’5″–5’11”, 10 ft for 6’0″ and above).
- Beginners should start with longer ropes for clearance.
What should you learn?
- Initial jump rope skills: start with manageable daily jump totals, gradually increasing as ankles, calves, and feet adapt.
- Further skills: learn the two-foot jump and then the boxer’s skip for efficient, longer sessions and advanced skills. Keep arms close and hands at waist level for a smooth swing.
For more on all of this, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like to read:
How To Do High Intensity Interval Training (Without Wrecking Your Body)
Take care!
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Strong Curves – by Bret Contreras & Kellie Davis
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The title (and subtitle) is, of course, an appeal to vanity. However, the first-listed author is well-known as “The Glute Guy”, and he takes this very seriously, not just for aesthetic reasons but also for practical reasons.
After all, when it comes to posture and stability, a lot rests on our hips, and hips, well, they rest on our butt and thighs. What’s more, the gluteus maximus is the largest muscle in the human body, so really, is it a good one to neglect? Probably not, and your lower back will definitely thank you for keeping your glutes in good order, too.
That said, while it’s a focal point, it’s not the be-all-and-end-all, and this book does cover the whole body.
The book takes the reader from “absolute beginner” to “could compete professionally”, with clearly-illustrated and well-described exercises. We also get a strong “crash course” in the relevant anatomy and physiology, and even a chapter on nutrition, which is a lot better than a lot of exercise books’ efforts in that regard.
For those who like short courses, this book has several progressive 12-week workout plans that take the reader from a very clear starting point to a very clear goal point.
Another strength of the book is that while a lot of exercises expect (and require) access to a gym, there are also whole sections of “at home / bodyweight” exercises, including 12-week workout plans for such, as described above.
Bottom line: there’s really nothing bad that this reviewer can find to say about this one—highly recommendable to any woman who wants to get strong while keeping a feminine look.
Click here to check out Strong Curves, and rebuild your body, your way!
PS: at first glance, the cover art looks like an AI model; it’s not; that’s the co-author Kellie Davis, who also serves as the model through the book’s many photographic illustrations.
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Early Bird Or Night Owl? Genes vs Environment
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A Sliding Slope?
In Tuesday’s newsletter, we asked you how much control you believe we have over our sleep schedule, and got the above-depicted, below-described, set of responses:
- 45% said “most people can control it; some people with sleep disorders cannot
- 35% said “our genes predispose us to early/late, but we can slide it a bit
- 15% said: “going against our hardwired sleep schedules is a road to ruin”
- 5% said “anyone can adjust their sleep schedule with enough willpower”
You may be wondering: what’s with those single-digit numbers in the graph there? And the answer is: Tuesday’s email didn’t go out at the usual time due to a scheduling mistake (sorry!), which is probably what affected the number of responses (poll response levels vary, but are usually a lot higher than this).
Note: yes, this does mean most people who read our newsletter don’t vote. So, not to sound like a politician on the campaign trail, but… Your vote counts! We always love reading your comments when you add those, too—often they provide context that allow us to tailor what we focus on in our articles
However, those are the responses we got, so here we are!
What does the science say?
Anyone can adjust their sleep with enough willpower: True or False?
False, simply. It’s difficult for most people, but for many people with sleep disorders, it is outright impossible.
In a battle of narcolepsy vs willpower, for example, no amount of willpower will stop the brain from switching to sleep mode when it thinks it’s time to sleep:
❝Narcolepsy is the most common neurological cause of chronic sleepiness. The discovery about 20 years ago that narcolepsy is caused by selective loss of the neurons producing orexins sparked great advances in the field
[There is also] developing evidence that narcolepsy is an autoimmune disorder that may be caused by a T cell-mediated attack on the orexin neurons and explain how these new perspectives can inform better therapeutic approaches.❞
~ Dr. Carrie Mahoney et al. (lightly edited for brevity)
Source: The neurobiological basis of narcolepsy
For further reading, especially if this applies to you or a loved one:
Our genes predispose us to early/late, but we can slide it a bit: True or False?
True! First, about our genes predisposing us:
…and also:
Gene distinguishes early birds from night owls and helps predict time of death
Now, as for the “can slide it a bit”, this is really just a function of the general categories of “early bird” and “night owl” spanning periods of time that allow for a few hours’ wiggle-room at either side.
However, it is recommended to make any actual changes more gradually, with the Sleep Foundation going so far as to recommend 30 minutes, or even just 15 minutes, of change per day:
Sleep Foundation | How to Fix Your Sleep Schedule
Going against our hardwired sleep schedule is a road to ruin: True or False?
False, contextually. By this we mean: our “hardwired” sleep schedule is (for most of us), genetically predisposed but not predetermined.
Also, genetic predispositions are not necessarily always good for us; one would not argue, for example, for avoiding going against a genetic predisposition to addiction.
Some genetic predispositions are just plain bad for us, and genes can be a bit of a lottery.
That said, we do recommend getting some insider knowledge (literally), by getting personal genomics tests done, if that’s a viable option for you, so you know what’s really a genetic trait (and what to do with that information) and what’s probably caused by something else (and what to do with that information):
Genetic Testing: Health Benefits & Methods
Take care!
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Cynthia’s Thoughts on Intermittent Fasting
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The Myth of Breakfast and Snacking
Here at 10almonds we love addressing misconceptions in the health world.
When it comes to eating habits and fasting, we’ve written our own pieces on how to break your fast (otherwise known as break-fast, or breakfast), alongside a general breakdown of intermittent fasting, and a much-requested piece on fasting specifically for women.
Cynthia Thurlow, though, instead of just writing a few articles, has dedicated the majority of her working years to intermittent fasting and, in her TEDx talk (below), makes a strong argument challenging the long-held belief that breakfast is the most important meal of the day.
Cynthia Thurlow’s Two Main Points
Thurlow argues that it’s not what you eat but when you eat that has a more profound impact on health and aging. And she argues this is crucial regardless of your age.
Complementing her views on fasting are her views on snacking; she argues that snacking all day long is outdated advice and can overtax the digestive system, leading to various health issues.
Practical Tips for Starting Intermittent Fasting
To begin intermittent fasting, Thurlow suggests starting with a 12-13 hour fasting window and gradually increasing it to 16 hours.
In terms of food choice, she recommends eating whole, unprocessed foods during eating periods as well as staying well-hydrated with water, coffee, or tea.
But you won’t see results immediately; Thurlow advises giving the strategy a solid 30 days to see results and consulting a healthcare provider if there are any existing health conditions.
You can dive deeper and join the 15 million other people who have listened to her thoughts on fasting by watching her TEDx talk below:
How was the video? If you’ve discovered any great videos yourself that you’d like to share with fellow 10almonds readers, then please do email them to us!
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Licorice, Digestion, & Hormones
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Let’s Take A Look At Licorice…
Licorice, as a confectionary, is mostly sugar and is useless for medicinal purposes.
Licorice (Glycyrrhiza sp., most often Glycyrrhiza glabra), in the form of either the root extract (which can be taken as a supplement, or used topically) or the whole root (which can be taken as a powder/capsule, or used to make tea), is a medicinal plant with a long history of use.
How well-evidenced is it for its popular uses?
Licorice for digestion
In this case, it is more accurate to say that it combats indigestion, including acid reflux and ulcerative colitis:
Systematic Review on Herbal Preparations for Controlling Visceral Hypersensitivity in Functional Gastrointestinal Disorders ← licorice was a top-tier performer in this review
Network pharmacology mechanisms and experimental verification of licorice in the treatment of ulcerative colitis ← looking at the mechanism of action; ultimately they concluded that “licorice improves ulcerative colitis, which may be related to the activation of the Nrf2/PINK1 signaling pathway that regulates autophagy.“
Licorice vs menopause symptoms
This one, while a popular use, isn’t so clear. Here’s a study that examines the compounds in licorice (in this case, Glycyrrhiza uralensis) that interact with estrogen receptors, notes that the bioavailability is poor, and proposes, tests, and recommends a way to make it more bioavailable:
On the other hand, it is established that it will lower serum testosterone levels, which may make it beneficial for menopause and/or PCOS:
Polycystic ovaries and herbal remedies: A systematic review
Licorice for men
You may be wondering: what about for men? Well, the jury is out on whether it meaningfully reduces free testosterone levels:
Licorice consumption and serum testosterone in healthy men
See also:
And finally, it may (notwithstanding its disputed effect on testosterone itself) be useful as a safer alternative to finasteride (an antiandrogen mostly commonly used to treat benign prostatic hyperplasia, also used to as a hair loss remedy), since it (like finasteride) modulates 5α-reductase activity (this enzyme converts testosterone to the more potent dihydrogen testosterone, DHT), without lowering sperm count:
Licorice for the skin
As well as its potentially estrogenic activity, its anti-inflammatory and antioxidant powers make it comparable to hydrocortisone cream for treating eczema, psoriasis, and other such skin conditions:
New Herbal Biomedicines for the Topical Treatment of Dermatological Disorders
Is it safe?
It is “generally recognized as safe”, as the classification goes.
However, consumed in excess it can cause/worsen hypertension, and other contraindications include if you’re on blood thinners, or have kidney problems.
As ever, this is a non-exhaustive list, so do speak with your doctor/pharmacist to be sure.
Want to try some?
We don’t sell it, but here for your convenience is an example product on Amazon
Enjoy!
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Sweet Spot for Brain Health – by Dr. Sui Wong
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At 10almonds we often mention that “what’s good for the heart is good for the brain”, but at least in part, it’s because (as this book makes very clear), “what’s good for the blood is good for the brain”. After all, our brain uses about 25% of our energy, and that energy is delivered there by the blood. And if it doesn’t get enough nutrients, oxygen, etc, and detritus isn’t taken away, then problems happen.
Dr. Wong discusses Alzheimer’s as heavily driven by metabolic problems such as diabetes and even pre-diabetes, and sets out to put in our hands the guidebook to not only not doing that, but also, actually making sure our brain gets proper nourishment without delivering that as intermittent sugar spikes because we opted for a something with very fast-acting carbs to perk us up energetically.
More than most books on the topic, she talks a lot about the neurobiology of glucose metabolism, so that’s something that really sets this book apart from many of its genre.
The style is narrative, explaining the body’s processes in a clear fashion, without skimping on science. There are definitely words that your average layperson might not know, but they’re explained as we go, and there are frequent recaps of what we learned previously, making for ultimately easy reading.
After all the information is given, there’s also a guided “12-week challenge” with a theme-of-the-week for each week, to integrate a new lifestyle adjustment each week in a progressive fashion so that without needing to drastically change many things at once, we get where we need to be in terms of healthy habits.
Bottom line: if you’d like to do right by your brain and while you’re at it say goodbye to blood sugar highs and lows, then this book is an excellent guide for that.
Click here to check out Sweet Spot For Brain Health, and enjoy a consistently-energized brain!
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