
How Intermittent Fasting Reduces Heart Attack Risk (Directly, Not Via Weight Control!)
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We’ve written before about the benefits of intermittent fasting, such as:
- Intermittent Fasting: What’s The Truth?
- 16/8 Intermittent Fasting For Beginners
- Before You Eat Breakfast: 3 Surprising Facts About Intermittent Fasting
Intermittent fasting is mostly enjoyed for its metabolic benefits, such as How To Prevent And Reverse Type 2 Diabetes.
We also covered a very related topic, with intermittent fasting once again being on the suggestions list:
Improve Your Insulin Sensitivity! ← this is actually more important even that blood sugar control itself, important as that latter is!
So, how does it work to reduce heart attack risk?
While intermittent fasting can be used as a weight loss tool (it also doesn’t have to be—it depends on what you eat and what you’re doing in terms of exercise, amongst other factors), this isn’t about that.
Although it is also worth mentioning that intermittent fasting does reduce the risks associated with diabetes, hypercholesterolemia, cancer, Alzheimer’s, and more, as well as generally improving cardiovascular health by reducing blood pressure, cholesterol, and insulin resistance, amongst other metrics.
However, this is about platelet aggregation. Or in whole: platelet activation, aggregation, and thrombosis.
A team of scientists, Dr. Shimo Dai et al., investigated the effects of alternate-day intermittent fasting on platelets and thrombosis, in two quite different, but both important, demographics:
- Humans with coronary artery disease
- Mice with the ApoE gene (the Alzheimer’s risk gene)
Why the mice? Because they wanted to check the level of cerebral ischemia-reperfusion injury (the damage that occurs after a stroke), and no ethics board will let scientists slice up human participants brains at will.
In both cases, the intermittent fasting group enjoyed protective effects that the control group (ad libitum eating) did not.
Specifically, reduced platelet activation, as well as reduced platelet aggregation. Just to be clear:
- Platelet activation = platelets getting deployed
- Platelet aggregation = platelets sticking together
Both are required for thrombosis, which occurs when the platelets, having been activated and aggregated (which is their job, for example to stop bleeding in the case of an injury), block one or more blood vessels.
A healthy level of platelet activation and aggregation rests in the sweet spot wherefrom it can stop bleeding, without stopping blood circulation.
This was found to be associated with increased levels of indole-3-propionic acid (IPA), which is created by certain gut bacteria (C. sporogenes), who proliferate enthusiastically during intermittent fasting.
In few words:
- intermittent fasting triggers the C. sporogenes to proliferate,
- which increases IPA levels,
- which reduces platelet activation and aggregation,
- which reduces the risk of thrombosis,
- and thus reduces the risk of heart attack.
We may hypothesize that this may be a reason to not do intermittent fasting if you have a bleeding disorder, and consult your doctor if you’re on blood thinners.
For everyone else, this is one more thing that makes intermittent fasting a very healthful practice!
You can find the paper itself here:
And here’s a pop-science article that gets more technical than we have, if you’d like a middle-ground in terms of complexity:
Intermittent fasting cuts heart attack risk by preventing dangerous blood clots
Want to try intermittent fasting, but it sounds hard?
Check out this:
Enjoy!
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How I Cured My Silent Reflux – by Don Daniels
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Acid reflux, in its various forms (not all of which include heartburn as a symptom!), affects around 1 in 8 people. Often it takes the form of coughing or excess mucus after eating, and it can trigger ostensibly random sweats, for example.
Don Daniels does an excellent job of demystifying the various kinds of acid reflux, explaining clearly and simply the mechanics of what is going on for each of them and why.
Further, he talks about the medications that can make things worse (and how and why), and supplements that can make it better (and supplements that can make it worse, too!), and a multiphase plan (diet on, meds weaned off, supplements on, supplements weaned off when asymptomatic, diet adjust to a new normal) to get free from acid reflux.
The writing style is simple, clear, and jargon-free, while referencing plenty of scientific literature, often quoting from it and providing sources, much like we often do at 10almonds. There are 50+ such references in all, for a 105-page book.
So, do also note that yes, it’s quite a short book for the price, but the content is of value and wouldn’t have benefitted from padding of the kind that many authors do just to make the book longer.
Bottom line: if you have, or suspect you may have, an acid reflux condition of any kind, then this book can guide you through fixing that.
Click here to check out How I Cured My Silent Reflux, and put up with it no longer!
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Avoid Knee Surgery With This Proven Strategy (Over-50s Specialist Physio)
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A diagnosis of knee arthritis can be very worrying, but it doesn’t necessarily mean a knee replacement surgery is inevitable. Here’s how to keep your knee better, for longer (and potentially, for life):
Flexing your good health
You know we wouldn’t let that “proven” go by unchallenged if it weren’t, so what’s the evidence for it? Research (papers linked in the video description) showed 70% of patients (so, not 100%, but 70% is good odds and a lot better than the alternative) with mild to moderate knee arthritis avoided surgery after following a specific protocol—the one we’re about to describe.
The key strategy is to focus on strengthening the quadriceps muscles for joint protection, as strong quads correlate with reduced pain. However, a full range of motion in the knee is essential for optimal quad function, so that needs attention too, and in fact is foundational (can’t strengthen a quadriceps that doesn’t have a range of motion available to it):
Steps to follow:
- Improve knee extension:
- Passive knee extension exercise: gently press your knee down while lying flat, to increase straightening.
- Weighted heel props: use light weights to encourage gradual knee straightening.
- Enhance knee flexion:
- Use a towel to gently pull the knee towards the body to improve bending range.
Regular practice (multiple times daily) leads to improved knee function and pain relief. Exercises should be performed gently and without pain, aiming for consistent, gradual progress.And of course, if you do experience pain, it is recommend to consult with a local physiotherapist for more personalized guidance.
For more on all of this plus visual demonstrations, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like to read:
Treat Your Own Knee – by Robin McKenzie
Take care!
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- Improve knee extension:
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Are Waist Trainers Just A Waste, And Are Posture Fixers A Quick Fix?
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Are Waist Trainers Just A Waste, And Are Posture Fixers A Quick Fix?
Yesterday, we asked you for your opinions on waist trainers and posture-fixing harnesses, and got the above-depicted, below-described set of results:
- The most popular response was “Waist trainers are purely cosmetic, so useless. Posture-fixers have merit”, with a little over a quarter of the votes.
- The least popular response was “Both are great tools to help us to optimal waist size and posture, respectively!”
- The other three answers each got a little under a quarter of the vote. In terms of discrete data, these were all 7±1, so basically, there was nothing in it.
The sample size was smaller than usual—perhaps the cluster of American holiday dates yesterday and today kept people busy! But, pressing on…
What does the science say?
Waist trainers are purely cosmetic, so, useless. True or False?
True, simply. Honestly, they’re not even that great for cosmetic purposes. They will indeed cinch in your middle, and this shape will be retained for a (very) short while after uncinching, because your organs have been squished inwards and may take a short while to get back to where they are supposed to be.
The American Board of Cosmetic Surgery may not be an unbiased source, but we’re struggling to find scientists who will even touch one of these, so, let’s see what these doctors have to say:
- Waist training can damage vital organs
- You will be slowly suffocating yourself
- Waist training simply doesn’t work
- You cannot drastically change your body shape with a piece of fabric*
Read: ABCS | 4 Reasons to Throw Your Waist Trainer in the Trash
*”But what about foot-binding?”—feet have many bones, whose growth can be physically restricted. Your waist has:
- organs: necessary! (long-term damage possible, but they’re not going away)
- muscles: slightly restrictable! (temporary restriction; no permanent change)
- fat: very squeezable! (temporary muffin; no permanent change)
Posture correctors have merit: True or False?
True—probably, and as a stepping-stone measure only.
The Ergonomics Health Association (a workplace health & safety organization) says:
❝Looking at the clinical evidence of posture correctors, we can say without a doubt that they do work, just not for everyone and not in the same way for all patients.❞
Source: Do Posture Correctors Work? Here’s What Our Experts Think
That’s not very compelling, so we looked for studies, and found… Not much, actually. However, what we did find supported the idea that “they probably do help, but we seriously need better studies with less bias”:
That is also not a compelling title, but here is where it pays to look at the studies and not just the titles. Basically, they found that the results were favorable to the posture-correctors—the science itself was just trash:
❝ The overall findings were that posture-correcting shirts change posture and subjectively have a positive effect on discomfort, energy levels and productivity.
The quality of the included literature was poor to fair with only one study being of good quality. The risk of bias was serious or critical for the included studies. Overall, this resulted in very low confidence in available evidence.❞
Since the benefit of posture correctors like this one is due to reminding the wearer to keep good posture, there is a lot more (good quality!) science for wearable biofeedback tech devices, such as this one:
Spine Cop: Posture Correction Monitor and Assistant
Take care!
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Does This New Machine Cure Depression?
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Let us first talk briefly about the slightly older tech that this may replace, transcranial magnetic stimulation (TMS).
TMS involves electromagnetic fields to stimulate the left half of the brain and inhibit the right half of the brain. It sounds like something from the late 19th century—“cure your melancholy with the mystical power of magnetism”—but the thing is, it works:
The main barriers to its use are that the machine itself is expensive, and it has to be done in a clinic by a trained clinician. Which, if it were treating one’s heart, say, would not be so much of an issue, but when treating depression, there is a problem that depressed people are not the most likely to commit to (and follow through with) going somewhere probably out-of-town regularly to get a treatment, when merely getting out of the door was already a challenge and motivation is thin on the ground to start with.
Thus, antidepressant medications are more often the go-to for cost-effectiveness and adherence. Of course, some will work better than others for different people, and some may not work at all in the case of what is generally called “treatment-resistant depression”:
Antidepressants: Personalization Is Key!
Transcranial stimulation… At home?
Move over transcranial magnetic stimulation; it’s time for transcranial direct-current stimulation (tDCS).
First, what it’s not: electroconvulsive therapy (ECT). Rather, it uses a very low current.
What it is: a small and portable headset (as opposed to the big machine to go sit in for TMS) that one can use at home. Here’s an example product on Amazon, though there are more stylish versions around, this is the same basic technology.
In a recent study, 45% of those who received treatment with this device experienced remission in 10 weeks, significantly beating placebo (bearing in mind that placebo effect is strongest when it comes to invisible ailments such as depression).
See also: How To Leverage Placebo Effect For Yourself ← this explains more about how the placebo effect works, to the extent that it can even be an adjuvant tool to augment “real” therapies
And as for the study, here it is:
…which rather cuts through the “depressed people don’t make it to the clinic consistently, if at all” problem. Of course, it still requires adherence to its use at home, for example three 30-minute sessions per week, but honestly, “lie/sit still” is likely within the abilities of the majority of depressed people. However…
Important note: you remember we said “in 10 weeks”? That may be critical, because shorter studies (e.g. 6 weeks) have previously returned without such glowing results:
Home-Use Transcranial Direct Current Stimulation for the Treatment of a Major Depressive Episode
This means that if you get this tech for yourself or a loved one, it’ll be necessary to persist for likely 10 weeks, certainly more than 6 weeks, and not abandon it after a few sessions when it hasn’t been life-changing yet. And that may be more of a challenge for a depressed person, so likely an “accountability buddy” of some kind is in order (partner, close friend, etc) to help ensure adherence and generally bug you/them into doing it consistently.
And then, of course, you/they might still be in the 55% of people for whom it didn’t work. And that does suck, but random antidepressant medications (i.e., not personalized) don’t fare much better, statistically.
Want something else against depression meanwhile?
Here are some strategies that not only can significantly help, but also are tailored to be actually doable while depressed:
The Mental Health First-Aid You’ll Hopefully Never Need ← written by your writer who has previously suffered extensively from depression and knows what it is like
Take care!
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Dopamine Nation – by Dr. Anna Lembke
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We live in an age of abundance, though it often doesn’t feel like it. Some of that is due to artificial scarcity, but a lot of it is due to effectively whiting out our dopamine circuitry through chronic overuse.
Psychiatrist Dr. Anna Lembke explores the neurophysiology of pleasure and pain, and how each can (and does) lead to the other. Is the answer to lead a life of extreme neutrality? Not quite.
Rather, simply by being more mindful of how we seek each (yes, both pleasure and pain), we can leverage our neurophysiology to live a better, healthier life—and break/avoid compulsive habits, while we’re at it.
That said, the book itself is quite compelling reading, but as Dr. Lembke shows us, that certainly doesn’t have to be a bad thing.
Bottom line: if you sometimes find yourself restlessly cycling through the same few apps (or TV channels) looking for dopamine that you’re not going to find there, this is the book for you.
Click here to check out Dopamine Nation, and get a handle on yours!
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What are plyometric exercises? How all that hopping and jumping builds strength, speed and power
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If you’ve ever seen people at the gym or the park jumping, hopping or hurling weighted balls to the ground, chances are they were doing plyometric exercises.
Examples include:
- box jumps, where you repeatedly leap quickly on and off a box
- lateral skater hops, where you bound from side to side like a speeding ice skater
- rapidly throwing a heavy medicine ball against a wall, or to the ground
- single leg hops, which may involve hopping on the spot or through an obstacle course
- squat jumps, where you repeatedly squat and then launch yourself into the air.
Photo by cottonbro studio/Pexels There are many more examples of plyometric exercises.
What ties all these moves together is that they use what’s known as the “stretch shortening cycle”. This is where your muscles rapidly stretch and then contract.
Runners routinely practise plyometric exercises to improve explosive leg strength. WoodysPhotos/Shutterstock Potential benefits
Research shows incorporating plyometric exercise into your routine can help you:
- jump higher
- sprint faster
- reduce the chances of getting a serious sporting injuries such as anterior cruciate ligament (ACL) tears
- build muscle strength
- improve bone mineral density (especially when combined with resistance training such as weight lifting), which is particularly important for women and older people at risk of falls.
Studies have found plyometric exercises can help:
- older people who want to retain and build muscle strength, boost bone health, improve posture and reduce the risk of falls
- adolescent athletes who want to build the explosive strength needed to excel in sports such as athletics, tennis, soccer, basketball and football
- female athletes who want to jump higher or change direction quickly (a useful skill in many sports)
- endurance runners who want to boost physical fitness, run time and athletic performance.
And when it comes to plyometric exercises, you get out what you put in.
Research has found the benefits of plyometrics are significantly greater when every jump was performed with maximum effort.
Jumping can help boost bone strength. WoodysPhotos/Shutterstock Potential risks
All exercise comes with risk (as does not doing enough exercise!)
Plyometrics are high-intensity activities that require the body to absorb a lot of impact when landing on the ground or catching medicine balls.
That means there is some risk of musculoskeletal injury, particularly if the combination of intensity, frequency and volume is too high.
You might miss a landing and fall, land in a weird way and crunch your ankle, or get a muscle tear if you’re overdoing it.
The National Strength and Conditioning Association, a US educational nonprofit that uses research to support coaches and athletes, recommends:
- a maximum of one to three plyometric sessions per week
- five to ten repetitions per set and
- rest periods of one to three minutes between sets to ensure complete muscle recovery.
With the right guidance, jumps can be safe for older people and may help reduce the risk of falls as you age. Realstock/Shutterstock One meta-analysis, where researchers looked at many studies, found plyometric training was feasible and safe, and could improve older people’s performance, function and health.
Overall, with appropriate programming and supervision, plyometric exercise can be a safe and effective way to boost your health and athletic performance.
Justin Keogh, Associate Dean of Research, Faculty of Health Sciences and Medicine, Bond University and Mandy Hagstrom, Senior Lecturer, Exercise Physiology. School of Health Sciences, UNSW Sydney
This article is republished from The Conversation under a Creative Commons license. Read the original article.
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