Cognitive Enhancement Without Drugs

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Cognitive Enhancement Without Drugs

Elizabeth Ricker stands before the tranquil ocean, contemplating the vast expanse before her.

This is Elizabeth Ricker. She’s a Harvard-and-MIT-trained neuroscientist and researcher, who now runs the “Citizen Science” DIY-neurohacking organization, NeuroEducate.

Sounds fun! What’s it about?

The philosophy that spurs on her research and practice can be summed up as follows:

❝I’m not going to leave my brain up to my doctor or [anyone else]… My brain is my own responsibility, and I’m going to do the best that I can to optimize it❞

Her goal is not just to optimize her own brain though; she wants to make the science accessible to everyone.

What’s this about Citizen Science?

Citizen Science” is the idea that while there’s definitely an important role in society for career academics, science itself should be accessible to all. And, not just the conclusions, but the process too.

This can take the form of huge experiments, often facilitated these days by apps where we opt-in to allow our health metrics (for example) to be collated with many thousands of others, for science. It can also involve such things as we talked about recently, getting our own raw genetic data and “running the numbers” at home to get far more comprehensive and direct information than the genetic testing company would ever provide us.

For Ricker, her focus is on the neuroscience side of biohacking, thus, neurohacking.

I’m ready to hack my brain! Do I need a drill?

Happily not! Although… Bone drills for the skull are very convenient instruments that make it quite hard to go wrong even with minimal training. The drill bit has a little step/ledge partway down, which means you can only drill through the thickness of the skull itself, before the bone meeting the wider part of the bit stops you from accidentally drilling into the brain. Still, please don’t do this at home.

What you can do at home is a different kind of self-experimentation…

If you want to consider which things are genuinely resulting in cognitive enhancement and which things are not, you need to approach the matter like a scientist. That means going about it in an organized fashion, and recording results.

There are several ways cognitive enhancement can be measured, including:

  • Learning and memory
  • Executive function
  • Emotional regulation
  • Creative intelligence

Let’s look at each of them, and what can be done. We don’t have a lot of room here; we’re a newsletter not a book, but we’ll cover one of Ricker’s approaches for each:

Learning and memory

This one’s easy. We’re going to leverage neuroplasticity (neurons that fire together, wire together!) by simple practice, and introduce an extra element to go alongside your recall. Perhaps a scent, or a certain item of clothing. Tell yourself that clinical studies have shown that this will boost your recall. It’s true, but that’s not what’s important; what’s important is that you believe it, and bring the placebo effect to bear on your endeavors.

You can test your memory with word lists, generated randomly by AI, such as this one:

Random Word List Generator

You’ll soon find your memory improving—but don’t take our word for it!

Executive function

Executive function is the aspect of your brain that tells the other parts how to work, when to work, and when to stop working. If you’ve ever spent 30 minutes thinking “I need to get up” but you were stuck in scrolling social media, that was executive dysfunction.

This can be trained using the Stroop Color and Word Test, which shows you words, specifically the names of colors, which will themselves be colored, but not necessarily in the color the word pertains to. So for example, you might be shown the word “red”, colored green. Your task is to declare either the color of the word only, ignoring the word itself, or the meaning of the word only, ignoring its appearance. It can be quite challenging, but you’ll get better quite quickly:

The Stroop Test: Online Version

Emotional Regulation

This is the ability to not blow up angrily at the person with whom you need to be diplomatic, or to refrain from laughing when you thought of something funny in a sombre situation.

It’s an important part of cognitive function, and success or failure can have quite far-reaching consequences in life. And, it can be trained too.

There’s no online widget for this one, but: when and if you’re in a position to safely* do so, think about something that normally triggers a strong unwanted emotional reaction. It doesn’t have to be something life-shattering, but just something that you feel in some way bad about. Hold this in your mind, sit with it, and practice mindfulness. The idea is to be able to hold the unpleasant idea in your mind, without becoming reactive to it, or escaping to more pleasant distractions. Build this up.

*if you perchance have PTSD, C-PTSD, or an emotional regulation disorder, you might want to talk this one through with a qualified professional first.

Creative Intelligence

Another important cognitive skill, and again, one that can be cultivated and grown.

The trick here is volume. A good, repeatable test is to think of a common object (e.g. a rock, a towel, a banana) and, within a time constraint (such as 15 minutes) list how many uses you can think of for that item.

Writer’s storytime: once upon a time, I was sorting through an inventory of medical equipment with a colleague, and suggested throwing out our old arterial clamps, as we had newer, better ones—in abundance. My colleague didn’t want to part with them, so I challenged him “Give me one use for these, something we could in some possible world use them for that the new clamps don’t do better, and we’ll keep them”. He said “Thumbscrews”, and I threw my hands up in defeat, saying “Fine!”, as he had technically fulfilled my condition.

What’s the hack to improve this one? Just more volume. Creativity, as it turns out, isn’t something we can expend—like a muscle, it grows the more we use it. And because the above test is repeatable (with different objects), you can track your progress.

And if you feel like using your grown creative muscle to write/paint/compose/etc your magnum opus, great! Or if you just want to apply it to the problem-solving of everyday life, also great!

In summary…

Our brain is a wonderful organ with many functions. Society expects us to lose these as we get older, but the simple, scientific truth is that we can not only maintain our cognitive function, but also enhance and grow it as we go.

Want to know more from today’s featured expert?

You might enjoy her book, “Smarter Tomorrow”, which we reviewed back in March

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  • Intermittent Fasting for Women Over 50 – by Emma Sanchez

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Intermittent fasting is promoted as a very healthful (evidence-based!) way to trim the fat and slow aging, along with other health benefits. But, physiologically and especially metabolically, the average woman is quite different from the average man! And most resources are aimed at men. So, what’s the difference?

    Emma Sanchez gives an overview not just of intermittent fasting, but also, how it goes with specifically female physiology. From hormonal cycles, to different body composition and fat distribution, to how we simply retain energy better—which can be a mixed blessing!

    We’re given advice about how to optimize all those things and more.

    She also covers issues that many writers on the topic of intermittent fasting will tend to shy away from, such as:

    • mood swings
    • risk of eating disorder
    • impact on cognitive thinking

    …and she does this evenly and fairly, making the case for intermittent fasting while acknowledging potential pitfalls that need to be recognized in order to be managed.

    Lastly, the “over 50” thing. This is covered in detail quite late in the book, but there are a lot of changes that occur (beyond the obvious!), and once again, Sanchez has tips and tricks for holding back the clock where possible, and working with it rather than against it, when appropriate.

    All in all, a great book for any woman over 50, or really also for women under 50, especially if that particular milestone is on the horizon.

    Get your copy of Intermittent Fasting for Women over 50 from Amazon today!

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  • Insomnia? High blood pressure? Try these!

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Your Questions, Our Answers!

    Q: Recipes for insomnia and high blood pressure and good foods to eat for these conditions?

    A: Insomnia can be caused by many things, and consequently can often require a very multi-vector approach to fixing it. But, we’ll start by answering the question you asked (and probably address the rest of dealing with insomnia in another day’s edition!):

    • First, you want food that’s easy to digest. Broadly speaking, this means plant-based. If not plant-based, fish (unless you have an allergy, obviously) is generally good and certainly better than white meat, which is better than red meat. In the category of dairy, it depends so much on what it is, that we’re not going to try to break it down here. If in doubt, skip it.
    • You also don’t want blood sugar spikes, so it’s good to lay off the added sugar and white flour (or white flour derivatives, like white pasta), especially in your last meal of the day.
    • Magnesium supports healthy sleep. A fine option would be our shchi recipe, but using collard greens rather than cabbage. Cabbage is a wonderful food, but collard greens are much higher in magnesium. Remember to add plenty of mushrooms (unless you don’t like them), as they’re typically high in magnesium too.

    As for blood pressure, last month we gave tips (and a book recommendation) for heart health. The book, Dr. Monique Tello’s “Healthy Habits for Your Heart: 100 Simple, Effective Ways to Lower Your Blood Pressure and Maintain Your Heart’s Health”, also has recipes!

    Here’s one from the “mains” section:

    Secret Ingredient Baltimore-Style Salmon Patties with Not-Oily Aioli

    ❝This is a family favorite, and no one knows that it features puréed pumpkin! Most salmon cake recipes all for eggs and bread crumbs as binders, but puréed pumpkin and grated carrot work just as well, lend a beautiful color, and add plenty of fiber and plant nutrients. Canned salmon is way cheaper than fresh and has just as much omega-3 PUFAs and calcium. Serve this alongside a salad (the Summer Corn, Tomato, Spinach, and Basil Salad would go perfectly) for a well-rounded meal.❞

    Serves 4 (1 large patty each)

    Secret Ingredient Baltimore-Style Salmon Patties:

    • 1 (15-oz) can pink salmon, no salt added
    • ½ cup puréed pumpkin
    • ½ cup grated carrot (I use a handheld box grater)
    • 2 tablespoons minced chives (Don’t have chives? Minced green onions or any onions will do)
    • 2 teaspoons Old Bay Seasoning
    • 1 tablespoon olive oil
    • ½ large lemon, sliced, for serving

    Not-Oily Aioli:

    • ½ cup plain low-fat Greek yogurt
    • Juice and zest from ½ large lemon
    • 1 clove garlic, crushed and minced fine
    • 2 tablespoons chopped fresh dill
    1. For the patties: mix all the ingredients for the salmon patties together in a medium bowl
    2. Form patties with your hands and set on a plate or tray (you should have 4 burger-sized patties)
    3. Heat oil in a large skillet over medium heat.
    4. Set patties in a skillet and brown for 4 minutes, then carefully flip.
    5. Brown the other side, then serve hot.
    6. For the Aioli: mix all the ingredients for the aioli together in a small bowl.
    7. Plop a dollop alongside or on top of each salmon patty and serve with a spice of lemon.

    Per serving: Calories: 367 | Fat: 13.6g | Saturated Fat: 4.4g | Protein: 46g | Sodium: 519mg | Carbohydrates: 13.2g | Fiber: 1.3g | Sugars: 9g | Calcium: 505mg | Iron: 1mg | Potassium 696mg

    Notes from the 10almond team:

    • If you want to make it plant-based, substitute cooked red lentils (no salt added) for the tinned salmon, and plant-based yogurt for the Greek yogurt
    • We recommend adding more garlic. Seriously, who uses 1 clove of garlic for anything, let alone divided between four portions?
    • The salads mentioned are given as recipes elsewhere in the same book. We strongly recommend getting her book, if you’re interested in heart health!

    Do you have a question you’d like to see answered here? Hit reply or use the feedback widget at the bottom; we’d love to hear from you!

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  • L-Theanine: What’s The Tea?

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    L-Theanine: What’s The Tea?

    We’ve touched previously on l-theanine, when this newsletter was new, and we had only a few hundred subscribers and the carefully organized format wasn’t yet what it is today.

    So now it’s time to give this potent dietary compound / nutritional supplement the “Monday Research Review” treatment…

    What is it?

    L-theanine is an amino acid found in tea. The human body can’t produce it, and/but it’s not essential for humans. It does have a lot of benefits, though. See for example:

    L-Theanine as a Functional Food Additive: Its Role in Disease Prevention and Health Promotion

    How does it work?

    L-theanine works by moderating and modulating the brain’s neurotransmitters.

    This sounds fancy, but basically it means: it doesn’t actually add anything in the manner of a drug, but it changes how we use what we have naturally.

    What does it do? Read on…

    It increases mental focus

    It has been believed that l-theanine requires the presence of caffeine to achieve this (i.e., it’s a combination-only effect). For example:

    The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness

    But as it turns out, when a group of researchers actually checked… This isn’t true, as Foxe et al. write:

    ❝We asked whether either compound alone, or both in combination, would affect performance of the task in terms of reduced error rates over time, and whether changes in alpha-band activity would show a relationship to such changes in performance. When treated with placebo, participants showed a rise in error rates, a pattern that is commonly observed with increasing time-on-task, whereas after caffeine and theanine ingestion, error rates were significantly reduced. The combined treatment did not confer any additional benefits over either compound alone, suggesting that the individual compounds may confer maximal benefits at the dosages employed❞

    See: Assessing the effects of caffeine and theanine on the maintenance of vigilance during a sustained attention task

    It promotes a calmly wakeful feeling of serenity

    Those are not words typically found in biopharmaceutical literature, but they’re useful here to convey:

    • L-theanine promotes relaxation without causing drowsiness
    • L-theanine promotes mental alertness without being a stimulant

    Here is where l-theanine really stands out from caffeine. If both substances promote mental focus, but one of them does it by making us “wired” and the other does it while simultaneously promoting calm, it makes the choice between them clearer!

    Read more: L-theanine, a natural constituent in tea, and its effect on mental state

    It relieves stress and anxiety

    Building on from the above, but there’s more: l-theanine relieves stress and anxiety in people experiencing stressful situations, without any known harmful side effects… This is something that sets it apart from a lot of anxiolytic (antianxiety) drugs!

    Here’s what a big systematic review of clinical trials had to say:

    Theanine consumption, stress and anxiety in human clinical trials: A systematic review

    L-theanine has other benefits too

    We’ve talked about some of the most popular benefits of l-theanine, and we can’t make this newsletter too long, but research also suggests that it…

    If you’re interested in this topic, we recommend also reading our previous article on l-theanine—pardon that we hadn’t really nailed down our style yet—but there’s a bunch of useful information about how l-theanine makes caffeine “better” in terms of benefits. We also talk dosage, and reference some other studies we didn’t have room to include today!

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  • Gut-Healthy Sunset Soup

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    So-called for its gut-healthy ingredients, and its flavor profile being from the Maghreb (“Sunset”) region, the western half of the N. African coast.

    You will need

    • 1 can chickpeas (do not drain)
    • 1 cup low-sodium vegetable stock
    • 1 small onion, finely chopped
    • 1 carrot, finely chopped
    • 2 tbsp sauerkraut, drained and chopped (yes, it is already chopped, but we want it chopped smaller so it can disperse evenly in the soup)
    • 2 tbsp tomato paste
    • 1 tbsp harissa paste (adjust per your heat preference)
    • 1 tbsp ras el-hanout
    • ¼ bulb garlic, crushed
    • Juice of ½ lemon
    • ¼ tsp MSG or ½ tsp low-sodium salt
    • Extra virgin olive oil
    • Optional: herb garnish; we recommend cilantro or flat-leaf parsley

    Method

    (we suggest you read everything at least once before doing anything)

    1) Heat a little oil in a sauté pan or similar (something suitable for combination cooking, as we’ll be frying first and then adding liquids), and fry the onion and carrot until the onion is soft and translucent; about 5 minutes.

    2) Stir in the garlic, tomato paste, harissa paste, and ras el-hanout, and fry for a further 1 minute.

    3) Add the remaining ingredients* except the lemon juice. Bring to the boil and then simmer for 5 minutes.

    *So yes, this includes adding the “chickpea water” also called “aquafaba”; it adds flavor and also gut-healthy fiber in the form of oligosaccharides and resistant starches, which your gut microbiota can use to make short-chain fatty acids, which improve immune function and benefit the health in more ways than we can reasonably mention as a by-the-way in a recipe.

    4) Stir in the lemon juice, and serve, adding a herb garnish if you wish.

    Enjoy!

    Want to learn more?

    For those interested in some of the science of what we have going on today:

    Take care!

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  • 10 Tips To Reduce Morning Pain & Stiffness With Arthritis

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Physiotherapist and osteoarthritis specialist Dr. Alyssa Kuhn has professional advice:

    Just the tips

    We’ll not keep them a mystery; they are:

    1. Perform movements that target the range of motion in stiff joints, especially in knees and hips, to prevent them from being stuck in limited positions overnight.
    2. Use relaxation techniques like a hot shower, heating pad, or light reading before bed to reduce muscle tension and stiffness upon waking.
    3. Manage joint swelling during the day through gentle movement, compression sleeves, and self-massage .
    4. Maintain a balanced level of activity throughout the day to avoid excessive stiffness from either overactivity or, on the flipside, prolonged inactivity.
    5. Use pillows to support joints, such as placing one between your knees for hip and knee arthritis, and ensure you have a comfortable pillow for neck support.
    6. Eat anti-inflammatory foods prioritizing fruits and vegetables to reduce joint stiffness, and avoid foods high in added sugar, trans-fats, and saturated fats.
    7. Perform simple morning exercises targeting stiff areas to quickly relieve stiffness and ease into your daily routine.
    8. Engage in strength training exercises 2–3 times per week to build stronger muscles around the joints, which can reduce stiffness and pain.
    9. Ensure you get 7–8 hours of restful sleep, as poor sleep can increase stiffness and pain sensitivity the next day. 10almonds note: we realize there’s a degree of “catch 22” here, but we’re simply reporting her advice. Of course, do what you can to prioritize being able to get the best quality sleep you can.
    10. Perform gentle movements or stretches before bed to keep joints limber, focusing on exercises that feel comfortable and soothing.

    For more on each of these plus some visual demonstrations, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like to read:

    Take care!

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  • Does Ginseng Increase Testosterone Levels?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    ❓ Q&A With 10almonds Subscribers!

    Q: You talked about spearmint as reducing testosterone levels, what about ginseng for increasing them?

    A: Hormones are complicated and often it’s not a simple matter of higher or lower levels! It can also be a matter of…

    • how your body converts one thing into another
    • how your body responds (or not) to something according to how the relevant hormone’s receptors are doing
    • …and whether there’s anything else blocking those receptors.

    All this to say: spearmint categorically is an anti-androgen, but the mechanism of action remains uncertain.

    Panax ginseng, meanwhile, is one of the most well-established mysteries in herbal medicine.

    Paradoxically, it seems to improve both male and female hormonal regulation, despite being more commonly associated with the former.

    But it also…

    Bottom line: Panax ginseng is popularly taken to improve natural hormone function, a task at which it appears to excel.

    Scientists are still working out exactly how it does the many things it appears to do.

    Progress has been made, and it clearly is science rather than witchcraft, but there are still far more unanswered questions than resolved ones!

    Don’t Forget…

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