From Painkillers To Hunger-Killers
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Here’s this week’s selection of health news discoveries, the science behind them, what they mean for you, and where you can go from there:
Killing more than pain
It’s well-known that overuse of opioids can lead to many problems, and here’s another one: messing with the endocrine system. This time, mostly well-evidenced in men—however, the researchers are keen to point out that absence of evidence is very much not evidence of absence, hence “the hidden effects” in the headline below. It’s not that the effects are hard to see—it’s that a lot of the research has yet to be done. For now, though, we know at the very least that there’s an association between opioid use and hyperprolactinemia in men. The same research also begins to shine a light on the effects of opioid use on the hypothalamic-pituitary system and bone health, too:
Read in full: The hidden effects of opioid use on the endocrine system
Related: The 7 Approaches To Pain Management
Gut microbiome dysbiosis may lead to slipping disks
These things sound quite unconnected, but the association is strong. The likely mechanism of action is that the gut dysbiosis influences systemic inflammation, and thus spinal health—because the gut-spine axis cannot really be disconnected (while you’re alive, at least). It’s especially likely if you’re over 50 and female:
Read in full: Are back problems influenced by your gut?
Related: Is Your Gut Leading You Into Osteoporosis?
The Internet is really really great (for brains)
It’s common to see many articles on the Internet telling us, paradoxically, that we should spend less time on the Internet. However… Remember when in the 90s, it was all about “the information superhighway”? It turns out, the fact that it’s more like “the information spaghetti junction” these days doesn’t change the fact that stimulation is good for our brains, and daily Internet use improves memory, because of the different way that we index and store information that came from a virtual source. While there are parts of your brain for “things at home” and “things at the local supermarket”, there are also parts for “things at 10almonds” and “things at Facebook” and so forth. You are, in effect, building a vast mental library as you surf:
Read in full: Daily internet use supercharges your memory!
Related: Make Social Media Work For Your Mental Health
Fall back
Around this time of year in many places in the Northern Hemisphere, the clocks go back an hour (it’s next weekend in the US and Canada, by the way, and this weekend in most of Europe). Many enjoy this as the potential for an extra hour’s sleep, but for night owls, it can be more of a nuisance than a benefit—throwing out what’s often an already difficult relationship with the clock, and presenting challenges both practical and physiological (different processing of melatonin, for instance). Here be science:
Read in full: Why night owls struggle more when the clocks go back
Related: Early Bird Or Night Owl? Genes vs Environment
Can you outrun your hunger?
It seems so, though benefits are strongest in women. We say “outrun”, though this study did use stationary cycling. To put it in few words, intense exercise (but not moderate exercise) significantly reduced acylated ghrelin (hunger hormone) levels, and subjective reports of hunger, especially in women:
Read in full: Study finds intense exercise may suppress appetite in healthy humans
Related: 3 Appetite Suppressants Better Than Ozempic
Take care!
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From straight to curly, thick to thin: here’s how hormones and chemotherapy can change your hair
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Head hair comes in many colours, shapes and sizes, and hairstyles are often an expression of personal style or cultural identity.
Many different genes determine our hair texture, thickness and colour. But some people’s hair changes around the time of puberty, pregnancy or after chemotherapy.
So, what can cause hair to become curlier, thicker, thinner or grey?
Curly or straight? How hair follicle shape plays a role
Hair is made of keratin, a strong and insoluble protein. Each hair strand grows from its own hair follicle that extends deep into the skin.
Curly hair forms due to asymmetry of both the hair follicle and the keratin in the hair.
Follicles that produce curly hair are asymmetrical and curved and lie at an angle to the surface of the skin. This kinks the hair as it first grows.
The asymmetry of the hair follicle also causes the keratin to bunch up on one side of the hair strand. This pulls parts of the hair strand closer together into a curl, which maintains the curl as the hair continues to grow.
Follicles that are symmetrical, round and perpendicular to the skin surface produce straight hair.
Each hair strand grows from its own hair follicle.
Mosterpiece/ShutterstockLife changes, hair changes
Our hair undergoes repeated cycles throughout life, with different stages of growth and loss.
Each hair follicle contains stem cells, which multiply and grow into a hair strand.
Head hairs spend most of their time in the growth phase, which can last for several years. This is why head hair can grow so long.
Let’s look at the life of a single hair strand. After the growth phase is a transitional phase of about two weeks, where the hair strand stops growing. This is followed by a resting phase where the hair remains in the follicle for a few months before it naturally falls out.
The hair follicle remains in the skin and the stems cells grow a new hair to repeat the cycle.
Each hair on the scalp is replaced every three to five years.
Each hair on the scalp is replaced every three to five years.
Just Life/ShutterstockHormone changes during and after pregnancy alter the usual hair cycle
Many women notice their hair is thicker during pregnancy.
During pregnancy, high levels of oestrogen, progesterone and prolactin prolong the resting phase of the hair cycle. This means the hair stays in the hair follicle for longer, with less hair loss.
A drop in hormones a few months after delivery causes increased hair loss. This is due to all the hairs that remained in the resting phase during pregnancy falling out in a fairly synchronised way.
Hair can change around puberty, pregnancy or after chemotherapy
This is related to the genetics of hair shape, which is an example of incomplete dominance.
Incomplete dominance is when there is a middle version of a trait. For hair, we have curly hair and straight hair genes. But when someone has one curly hair gene and one straight hair gene, they can have wavy hair.
Hormonal changes that occur around puberty and pregnancy can affect the function of genes. This can cause the curly hair gene of someone with wavy hair to become more active. This can change their hair from wavy to curly.
Researchers have identified that activating specific genes can change hair in pigs from straight to curly.
Chemotherapy has very visible effects on hair. Chemotherapy kills rapidly dividing cells, including hair follicles, which causes hair loss. Chemotherapy can also have genetic effects that influence hair follicle shape. This can cause hair to regrow with a different shape for the first few cycles of hair regrowth.
Your hair can change at different stages of your life.
Igor Ivakhno/ShutterstockHormonal changes as we age also affect our hair
Throughout life, thyroid hormones are essential for production of keratin. Low levels of thyroid hormones can cause dry and brittle hair.
Oestrogen and androgens also regulate hair growth and loss, particularly as we age.
Balding in males is due to higher levels of androgens. In particular, high dihydrotestosterone (sometimes shortened to DHT), which is produced in the body from testosterone, has a role in male pattern baldness.
Some women experience female pattern hair loss. This is caused by a combination of genetic factors plus lower levels of oestrogen and higher androgens after menopause. The hair follicles become smaller and smaller until they no longer produce hairs.
Reduced function of the cells that produce melanin (the pigment that gives our hair colour) is what causes greying.
Theresa Larkin, Associate professor of Medical Sciences, University of Wollongong
This article is republished from The Conversation under a Creative Commons license. Read the original article.
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What Menopause Does To The Heart
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World Menopause Day: Menopause & Cardiovascular Disease Risk
Today, the 18th of October, is World Menopause Day.
The theme for this year is cardiovascular disease (CVD), and if your first reaction is to wonder what that has to do with the menopause, then this is the reason why it’s being featured. Much of the menopause and its effects are shrouded in mystery; not because of a lack of science (though sometimes a bit of that too), but rather, because it is popularly considered an unimportant, semi-taboo topic.
So, let’s be the change we want to see, and try to fix that!
What does CVD have to do with the menopause?
To quote Dr. Anjana Nair:
❝The metabolic and clinical factors secondary to menopause, such as dyslipidemia, insulin resistance, fat redistribution and systemic hypertension, contribute to the accelerated risk for cardiovascular aging and disease.
Atherosclerosis appears to be the end result of the interaction between cardiovascular risk factors and their accentuation during the perimenopausal period.
The increased cardiovascular risk in menopause stems from the exaggerated effects of changing physiology on the cardiovascular system.❞
Source: Cardiovascular Changes in Menopause
See also: Menopause-associated risk of cardiovascular disease
Can we do anything about it?
Yes, we can! Here be science:
- Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association
- Cardiovascular risk in menopausal women and our evolving understanding of menopausal hormone therapy: risks, benefits, and current guidelines for use
This (in few words: get your hormone levels checked, and consider HRT if appropriate) is consistent with the advice from gynecologist Dr. Jen Gunter, whom we featured back in August:
What You Should Have Been Told About The Menopause Beforehand
What about lifestyle changes?
We definitely can do some good things; here’s what the science has to say:
- Mediterranean diet: yes, evidence-based
- High soy consumption: mixed evidence, unclear. So, eat it if you want, don’t if you don’t.
- Supplements e.g. vitamins and minerals: yes, evidence-based.
- Supplements e.g. herbal preparations: many may help, but watch out for adverse interactions with meds. Check with your pharmacist or doctor.
- Supplements; specifically CBD: not enough evidence yet
- Exercise: yes, evidence-based—especially low-impact high-resistance training, for bone strength, as well as regular moderate-intensity exercise and/or High-Intensity Interval Training, to guard against CVD.
For a full low-down on all of these:
Revealing the evidence-based lifestyle solutions to managing your menopause symptoms
Want to know more?
You can get the International Menopause Society’s free downloadable booklet here:
Menopause & Cardiovascular Disease: What Women Need To Know
You may also like our previous main feature:
What Does “Balance Your Hormones” Even Mean?
Take care!
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Just One Thing – by Dr. Michael Mosley
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This is a collection of easy-to-implement changes that have good science behind them to show how they can benefit us. Some things are obvious (e.g: drink water); others, less so (e.g: sing, to reduce inflammation).
The book is divided thematically into times of the day, though in many cases it’s not a hard rule that a thing needs to be done at a certain time. Others are, like a cold shower in the morning and hot bath before bed—you might not want to switch those around!
The style is very pop-science, and does not have in-line citations for claims, but it does have a bibliography in the bag organized by each “one thing”, e.g. it might say “get some houseplants” and then list a number of references supporting that, with links to the studies showing how that helps. For those with the paper version, don’t worry, you can copy the URL from the book into your browser and see it that way. In any case, there are 2–6 scientific references for each claim, which is very respectable for a pop-sci book.
Bottom line: if you’re looking for evidence-based “one little thing” changes that can make a big difference, this book has lots!
Click here to check out Just One Thing, and improve your life!
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Happy Mind, Happy Life – by Dr. Rangan Chatterjee
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Let’s start with a “why”. If happiness doesn’t strike you as a worthwhile goal in and of itself, Dr. Chatterjee discusses the health implications of happiness/unhappiness.
And, yes, including in studies where other factors were controlled for, so he shows how happiness/unhappiness does really have a causal role in health—it’s not just a matter of “breaking news: sick people are less happy”.
The author, a British GP (General Practitioner, the equivalent of what the US calls a “family doctor”) with decades of experience, has found a lot of value in the practice of holistic medicine. For this reason, it’s what he recommends to his patients at work, in his books, his blog, and his regular spot on a popular BBC breakfast show.
The writing style is relaxed and personable, without skimping on information density. Indeed, Dr. Chatterjee offers many pieces of holistic health advice, and dozens of practical exercises to boost your happiness and proof you against adversity.
Because, whatever motivational speakers may say, we can’t purely “think ourselves happy”; sometimes we have real external threats and bad things in life. But, we can still improve our experience of even these things, not to mention suffer less, and get through it in better shape with a smile at the end of it.
Bottom line: if you’d like to be happier and healthier (who wouldn’t?), then this book is a sure-fire way to set you on that path.
Click here to check out Happy Mind, Happy Life and upgrade yours!
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“Unfuck Your Body” In Under 10 Minutes A Day!
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There’s a lot that can go wrong with mobility, but fortunately, a few compound exercises will take care of most parts of it:
Full Body Mobility Routine
Eleven exercises, 10 minutes, follow-along video if you want it!
Kneeling side bend stretch:
- Targets obliques, lats, hip flexors, and spinal mobility.
- 10 reps total, focusing on stability and core engagement.
Seated ankle stretch:
- This one’s for ankle mobility and deep squat comfort.
- 10 reps, adjust intensity by leaning forward or pressing on knees.
Deep squat with prayer stretch:
- Improves hip, ankle, and lower back flexibility.
- 10 reps, maintain an upright chest and push knees outward.
Deep squat with high reach:
- Boosts thoracic mobility, hip, and ankle flexibility.
- 5 reps per side, focus on spinal rotation and open chest.
Deep shoulder stretch:
- Improves overhead mobility and shoulder tension relief.
- 10 reps in a child’s pose position with a forward reach.
Frog rocks:
- Opens hip abductors, groin, and inner thighs.
- 10 reps, keep spine neutral and adjust knee position if needed.
“World’s greatest stretch” (with variations):
- This is great for hip, spine, and shoulder mobility.
- 5 reps per side, integrates a deep lunge and rotational movements.
Hamstring stretch (from lunge position):
- Focus on hamstring and calf flexibility.
- 5 reps, maintain hands on the ground and shift hips back.
Pigeon stretch with forward crawl:
- Opens hips, glutes, and lower back.
- 5 reps per side, adjust foot placement if knee discomfort occurs.
Cat-cow stretch:
- Mobilizes spine, improves posture, and relieves back tension.
- 10 reps, synchronize movement with breath.
Couch stretch:
- Targets hip flexors and quadriceps mobility.
- 5 reps per side, add a forward lunge for a deeper stretch.
For more on each of these plus visual demonstrations, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like:
5 Exercises That Fix 95% Of Your Problems
Take care!
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If Your Adult Kid Calls In Crisis…
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Parent(s) To The Rescue?
We’ve written before about the very common (yes, really, it is common) phenomenon of estrangement between parents and adult children:
Family Estrangement & How To Fix It
We’ve also written about the juggling act that can be…
Managing Sibling Relationships In Adult Life
…which includes dealing with such situations as supporting each other through difficult times, while still maintaining healthy boundaries.
But what about when one’s [adult] child is in crisis?
When a parent’s job never ends
Hopefully, we have not been estranged (or worse, bereaved) by our children.
In which case, when crisis hits, we are likely to be amongst the first to whom our children will reach out for support. Naturally, we will want to help. But how can we do that, and where (if applicable) to draw the line?
No “helicopter parenting”
If you’ve not heard the term “helicopter parenting”, it refers to the sort of parents who hover around, waiting to swoop in at a moment’s notice.
This is most often applied to parents of kids of university age and downwards, but it’s worth keeping it in mind at any age.
After all, we do want our kids to be able to solve their own problems if possible!
So, if you’ve ever advised your kid to “take a deep breath and count to 10” (or even if you haven’t), then, consider doing that too, and then…
Listen first!
If your first reaction isn’t to join them in panic, it might be to groan and “oh not again”. But for now, quietly shelve that, and listen to whatever it is.
See also: Active Listening (Without Sounding Like A Furby)
And certainly, do your best to maintain your own calm while listening. Your kid is in all likelihood looking to you to be the rock in the storm, so let’s be that.
Empower them, if you can
Maybe they just needed to vent. If so, the above will probably cover it.
More likely, they need help.
Perhaps they need guidance, from your greater life experience. Sometimes things that can seem like overwhelming challenges to one person, are a thing we dealt with 20 or more years ago (it probably felt overwhelming to us at the time, too, but here we are, the other side of it).
Tip: ask “are you looking for my guidance/advice/etc?” before offering it. Doing so will make it much more likely to be accepted rather than rejected as unsolicited advice.
Chances are, they will take the life-ring offered.
It could be that that’s not what they had in mind, and they’re looking for material support. If so…
When it’s about money or similar
Tip: it’s worth thinking about this sort of thing in advance (now is great, if you have adult kids), and ask yourself nowwhat you’d be prepared to give in that regard, e.g:
- if they need money, how much (if any) are you willing and able to provide?
- if they want/need to come stay with you, how prepared are you for that (including: if they want/need to actually move back in with you for a while, which is increasingly common these days)?
Having these answers in your head ready will make the conversation a lot less difficult in the moment, and will avoid you giving a knee-jerk response you might regret (in either direction).
Have a counteroffer up your sleeve if necessary
Maybe:
- you can’t solve their life problem for them, but you can help them find a therapist (if applicable, for example)
- you can’t solve their money problem for them, but you can help them find a free debt advice service (if applicable, for example)
- you can’t solve their residence problem for them, but you can help them find a service that can help with that (if applicable, for example)
You don’t need to brainstorm now for every option; you’re a parent, not Batman. But it’s a lot easier to think through such hypothetical thought-experiments now, than it will be with your fraught kid on the phone later.
Magic words to remember: “Let’s find a way through this for you”
Don’t forget to look after yourself
Many of us, as parents, will tend to not think twice before sacrificing something for our kid(s). That’s generally laudable, but we must avoid accidentally becoming “the giving tree” who has nothing left for ourself, and that includes our mental energy and our personal peace.
That doesn’t mean that when our kid comes in crisis we say “Shh, stop disturbing my personal peace”, but it does mean that we remember to keep at least some boundaries (also figure out now what they are, too!), and to take care of ourselves too.
The following article was written with a slightly different scenario in mind, but the advice remains just as valid here:
How To Avoid Carer Burnout (Without Dropping Care)
Take care!
Don’t Forget…
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Learn to Age Gracefully
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