Melatonin: A Safe, Natural Sleep Aid?

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Melatonin: A safe sleep supplement?

Melatonin is a hormone normally made in our pineal gland. It helps regulate our circadian rhythm, by making us sleepy.

It has other roles too—it has a part to play in regulating immune function, something that also waxes and wanes as a typical day goes by.

Additionally, since melatonin and cortisol are antagonistic to each other, a sudden increase in either will decrease the other. Our brain takes advantage of this, by giving us a cortisol spike in the morning to help us wake up.

As a supplement, it’s generally enjoyed with the intention of inducing healthy, natural, restorative sleep.

Does it really induce healthy, natural, restorative, sleep?

Yes! Well, “natural” is a little subject and relative, if you’re taking it as a supplement, but it’s something your body produces naturally anyway.

Contrast with, for example, benzodiazepines (that whole family of medications with names ending in -azopan or -alozam), or other tranquilizing drugs that do not so much induce healthy sleep, but rather reduce your brain function and hopefully knock you out, and/but often have unwanted side effects, and a tendency to create dependency.

Melatonin, unlike most of those drugs, does not create dependency, and furthermore, we don’t develop tolerance to it. In other words, the same dose will continue working (we won’t need more and more).

In terms of benefits, melatonin not only reduces the time to fall asleep and increases total sleep time, but also (quite a bonus) improves sleep quality, too:

Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders

Because it is a natural hormone rather than a drug with many side effects and interactions, it’s also beneficial for those who need good sleep and/but don’t want tranquilizing:

The Efficacy of Oral Melatonin in Improving Sleep in Cancer Patients with Insomnia: A Randomized Double-Blind Placebo-Controlled Study

Any other benefits?

Yes! It can also help guard against Seasonal Affective Disorder, also called seasonal depression. Because SAD is not just about “not enough light = not enough serotonin”, but also partly about circadian rhythm and (the body is not so sure what time of day it is when there are long hours of darkness, or even, in the other hemisphere / other time of year, long hours of daylight), melatonin can help, by giving your brain something to “anchor” onto, provided you take it at the same time each day. See:

As a small bonus, melatonin also promotes HGH production (important for maintaining bone and muscle mass, especially in later life):

Melatonin stimulates growth hormone secretion through pathways other than the growth hormone-releasing hormone

Anything we should worry about?

Assuming taking a recommended dose only (0.5mg–10mg per day), toxicity is highly unlikely, especially given that it has a half-life of only 40–60 minutes, so it’ll be eliminated quite quickly.

However! It does indeed induce sleepiness, so for example, don’t take melatonin and then try to drive or operate heavy machinery—or, ideally, do anything other than go to bed.

It can interfere with some medications. We mentioned that melatonin helps regulate immune function, so for example that’s something to bear in mind if you’re on immunosuppressants or otherwise have an autoimmune disorder. It can also interfere with blood pressure medications and blood thinners, and may make epilepsy meds less effective.

As ever, if in doubt, please speak with your doctor and/or pharmacist.

Where to get it?

As ever, we don’t sell it (or anything else), but for your convenience, here is an example product on Amazon.

Enjoy!

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  • Two Awesome Hours – by Dr. Josh Davis

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    The brain is an amazing and powerful organ, with theoretically unlimited potential in some respects. So why doesn’t it feel that way a lot of the time?

    The truth is that not only are we often tired, dehydrated, or facing other obvious physiological challenges to peak brain health, but also… We’re simply not making the best use of it!

    What Dr. Davis does is outline for us how we can create the conditions for “two awesome hours” of effective mental performance by:

    • Recognizing when to most effectively flip the switch on our automatic thinking
    • Scheduling tasks based on their “processing demand” and recovery time
    • Learning how to direct attention, rather than avoid distractions
    • Feeding and moving our bodies in ways that prep us for success
    • Identifying what matters in our environment to be at the top of our mental game

    Why only two hours? Why not four, or eight, or more?

    Well, our brains need recovery time too, so we can’t be “always on” and operating and peak efficiency. But, what we can do is optimize a couple of hours for absolute peak efficiency, and then enjoy the rest of time with lower cognitive-load activities.

    Bottom line: if the idea of what you could accomplish if you could just be guaranteed two schedulable hours (your preference when!) of peak cognitive performance per day, then this is a great book for you.

    Get your copy of “Two Awesome Hours” from Amazon today!

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  • Move – by Caroline Williams

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    • Get 150 minutes of moderate exercise per week, says the American Heart Association
    • There are over 10,000 minutes per week, says the pocket calculator

    Is 150/10,000 really the goal here? Really?

    For Caroline Williams, the answer is no.

    In this book that’s practically a manifesto, she outlines the case that:

    • Humans evolved to move
    • Industrialization and capitalism scuppered that
    • We now spend far too long each day without movement

    Furthermore, for Williams this isn’t just an anthropological observation, it’s a problem to be solved, because:

    • Our lack of movement is crippling us—literally
    • Our stagnation affects not just our bodies, but also our minds
      • (again literally—there’s a direct correlation with mental health)
    • We urgently need to fix this

    So, what now, do we need to move in to the gym and become full-time athletes to clock up enough hours of movement? No.

    Williams convincingly argues the case (using data from supercentenarian “blue zones” around the world) that even non-exertive movement is sufficient. In other words, you don’t have to be running; walking is great. You don’t have to be lifting weights; doing the housework or gardening will suffice.

    From that foundational axiom, she calls on us to find ways to build our life around movement… rather than production-efficiency and/or convenience. She gives plenty of tips for such too!

    Bottom line: some books are “I couldn’t put it down!” books. This one’s more of a “I got the urge to get up and get moving!” book.

    Get your get-up-and-go up and going with “Move”—order yours from Amazon today!

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  • Is It Dementia?

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    Spot The Signs (Because None Of Us Are Immune)

    Dementia affects increasingly many people, and unlike a lot of diseases, it disproportionately affects people in wealthy industrialized nations.

    There are two main reasons for this:

    • Longevity (in poorer countries, more people die of other things sooner; can’t get age-related cognitive decline if you don’t age)
    • Lifestyle (in the age of convenience, it has never been easier to live an unhealthy lifestyle)

    The former is obviously no bad thing for those of us lucky enough to be in wealthier countries (though even in such places, good healthcare access is of course sadly not a given for all).

    The latter, however, is less systemic and more epidemic. But it does cut both ways:

    • An unhealthy lifestyle is much easier here, yes
    • A healthier lifestyle is much easier here, too!

    This then comes down to two factors in turn:

    • Information: knowing about dementia, what things lead to it, what to look out for, what to do
    • Motivation: priorities, and how much attention we choose to give this matter

    So, let’s get some information, and then give it our attention!

    More than just memory

    It’s easy to focus on memory loss, but the four key disabilities directly caused by dementia (each person may not get all four), can be remembered by the mnemonic: “AAAA!”

    No, somebody didn’t just murder your writer. It’s:

    • Amnesia: memory loss, in one or more of its many forms
      • e.g. short term memory loss, and/or inability to make new memories
    • Aphasia: loss of ability to express oneself, and/or understand what is expressed
    • Apraxia: loss of ability to do things, through no obvious physical disability
      • e.g. staring at the bathroom mirror wondering how to brush one’s teeth
    • Agnosia: loss of ability to recognize things
      • e.g. prosopagnosia, also called face-blindness.

    If any of those seem worryingly familiar, be aware that while yes, it could be a red flag, what’s most important is patterns of these things.

    Another difference between having a momentary brainlapse and having dementia might be, for example, the difference between forgetting your keys, and forgetting what keys do or how to use one.

    That said, some are neurological deficits that may show up quite unrelated to dementia, including most of those given as examples above. So if you have just one, then that’s probably worthy of note, but probably not dementia.

    Writer’s anecdote: I have had prosopagnosia all my life. To give an example of what that is like and how it’s rather more than just “bad with faces”…

    Recently I saw my neighbor, and I could tell something was wrong with her face, but I couldn’t put my finger on what it was. Then some moments later, I realized I had mistaken her hat for her face. It was a large beanie with a panda design on it, and that was facelike enough for me to find myself looking at the wrong face.

    Subjective memory matters as much as objective

    Objective memory tests are great indicators of potential cognitive decline (or improvement!), but even a subjective idea of having memory problems, that one’s memory is “not as good as it used to be”, can be an important indicator too:

    Subjective memory may be marker for cognitive decline

    And more recently:

    If your memory feels like it’s not what it once was, it could point to a future dementia risk

    If you’d like an objective test of memory and other cognitive impairments, here’s the industry’s gold standard test (it’s free):

    SAGE: A Test to Detect Signs of Alzheimer’s and Dementia

    (The Self-Administered Gerocognitive Exam (SAGE) is designed to detect early signs of cognitive, memory or thinking impairments)

    There are things that can look like dementia that aren’t

    A person with dementia may be unable to recognize their partner, but hey, this writer knows that feeling very well too. So what sets things apart?

    More than we have room for today, but here’s a good overview:

    What are the early signs of dementia, and how does it differ from normal aging?

    Want to read more?

    You might like our previous article more specifically about reducing Alzheimer’s risk:

    Reducing Alzheimer’s Risk Early!

    Take care!

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  • I’ve been given opioids after surgery to take at home. What do I need to know?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Opioids are commonly prescribed when you’re discharged from hospital after surgery to help manage pain at home.

    These strong painkillers may have unwanted side effects or harms, such as constipation, drowsiness or the risk of dependence.

    However, there are steps you can take to minimise those harms and use opioids more safely as you recover from surgery.

    Flystock/Shutterstock

    Which types of opioids are most common?

    The most commonly prescribed opioids after surgery in Australia are oxycodone (brand names include Endone, OxyNorm) and tapentadol (Palexia).

    In fact, about half of new oxycodone prescriptions in Australia occur after a recent hospital visit.

    Most commonly, people will be given immediate-release opioids for their pain. These are quick-acting and are used to manage short-term pain.

    Because they work quickly, their dose can be easily adjusted to manage current pain levels. Your doctor will provide instructions on how to adjust the dosage based on your pain levels.

    Then there are slow-release opioids, which are specially formulated to slowly release the dose over about half to a full day. These may have “sustained-release”, “controlled-release” or “extended-release” on the box.

    Slow-release formulations are primarily used for chronic or long-term pain. The slow-release form means the medicine does not have to be taken as often. However, it takes longer to have an effect compared with immediate-release, so it is not commonly used after surgery.

    Controlling your pain after surgery is important. This allows you get up and start moving sooner, and recover faster. Moving around sooner after surgery prevents muscle wasting and harms associated with immobility, such as bed sores and blood clots.

    Everyone’s pain levels and needs for pain medicines are different. Pain levels also decrease as your surgical wound heals, so you may need to take less of your medicine as you recover.

    But there are also risks

    As mentioned above, side effects of opioids include constipation and feeling drowsy or nauseous. The drowsiness can also make you more likely to fall over.

    Opioids prescribed to manage pain at home after surgery are usually prescribed for short-term use.

    But up to one in ten Australians still take them up to four months after surgery. One study found people didn’t know how to safely stop taking opioids.

    Such long-term opioid use may lead to dependence and overdose. It can also reduce the medicine’s effectiveness. That’s because your body becomes used to the opioid and needs more of it to have the same effect.

    Dependency and side effects are also more common with slow-release opioids than immediate-release opioids. This is because people are usually on slow-release opioids for longer.

    Then there are concerns about “leftover” opioids. One study found 40% of participants were prescribed more than twice the amount they needed.

    This results in unused opioids at home, which can be dangerous to the person and their family. Storing leftover opioids at home increases the risk of taking too much, sharing with others inappropriately, and using without doctor supervision.

    Kitchen cupboard full of stockpiled medicine
    Don’t stockpile your leftover opioids in your medicine cupboard. Take them to your pharmacy for safe disposal. Archer Photo/Shutterstock

    How to mimimise the risks

    Before using opioids, speak to your doctor or pharmacist about using over-the-counter pain medicines such as paracetamol or anti-inflammatories such as ibuprofen (for example, Nurofen, Brufen) or diclofenac (for example, Voltaren, Fenac).

    These can be quite effective at controlling pain and will lessen your need for opioids. They can often be used instead of opioids, but in some cases a combination of both is needed.

    Other techniques to manage pain include physiotherapy, exercise, heat packs or ice packs. Speak to your doctor or pharmacist to discuss which techniques would benefit you the most.

    However, if you do need opioids, there are some ways to make sure you use them safely and effectively:

    • ask for immediate-release rather than slow-release opioids to lower your risk of side effects
    • do not drink alcohol or take sleeping tablets while on opioids. This can increase any drowsiness, and lead to reduced alertness and slower breathing
    • as you may be at higher risk of falls, remove trip hazards from your home and make sure you can safely get up off the sofa or bed and to the bathroom or kitchen
    • before starting opioids, have a plan in place with your doctor or pharmacist about how and when to stop taking them. Opioids after surgery are ideally taken at the lowest possible dose for the shortest length of time.
    Woman holding hot water bottle (pink cover) on belly
    A heat pack may help with pain relief, so you end up using fewer painkillers. New Africa/Shutterstock

    If you’re concerned about side effects

    If you are concerned about side effects while taking opioids, speak to your pharmacist or doctor. Side effects include:

    • constipation – your pharmacist will be able to give you lifestyle advice and recommend laxatives
    • drowsiness – do not drive or operate heavy machinery. If you’re trying to stay awake during the day, but keep falling asleep, your dose may be too high and you should contact your doctor
    • weakness and slowed breathing – this may be a sign of a more serious side effect such as respiratory depression which requires medical attention. Contact your doctor immediately.

    If you’re having trouble stopping opioids

    Talk to your doctor or pharmacist if you’re having trouble stopping opioids. They can give you alternatives to manage the pain and provide advice on gradually lowering your dose.

    You may experience withdrawal effects, such as agitation, anxiety and insomnia, but your doctor and pharmacist can help you manage these.

    How about leftover opioids?

    After you have finished using opioids, take any leftovers to your local pharmacy to dispose of them safely, free of charge.

    Do not share opioids with others and keep them away from others in the house who do not need them, as opioids can cause unintended harms if not used under the supervision of a medical professional. This could include accidental ingestion by children.

    For more information, speak to your pharmacist or doctor. Choosing Wisely Australia also has free online information about managing pain and opioid medicines.

    Katelyn Jauregui, PhD Candidate and Clinical Pharmacist, School of Pharmacy, Faculty of Medicine and Health, University of Sydney; Asad Patanwala, Professor, Sydney School of Pharmacy, University of Sydney; Jonathan Penm, Senior lecturer, School of Pharmacy, University of Sydney, and Shania Liu, Postdoctoral Research Fellow, Faculty of Medicine and Dentistry, University of Alberta

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • ‘It’s okay to poo at work’: new health campaign highlights a common source of anxiety

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    For most people, the daily or near-daily ritual of having a bowel motion is not something we give a great deal of thought to. But for some people, the need to do a “number two” in a public toilet or at work can be beset with significant stress and anxiety.

    In recognition of the discomfort people may feel around passing a bowel motion at work, the Queensland Department of Health recently launched a social media campaign with the message “It’s okay to poo at work”.

    The campaign has gained significant traction on Instagram and Facebook. It has been praised by health and marketing experts for its humorous handling of a taboo topic.

    A colourful Instagram post is accompanied by a caption warning of the health risks of “holding it in”, including haemorrhoids and other gastrointestinal problems. The caption also notes:

    If you find it extremely difficult to poo around other people, you might have parcopresis.

    Queensland Health/Instagram

    What is parcopresis?

    Parcopresis, sometimes called “shy bowel”, occurs when people experience a difficulty or inability to poo in public toilets due to fear of perceived scrutiny by others.

    People with parcopresis may find it difficult to go to the toilet in public places such as shopping centres, restaurants, at work or at school, or even at home when friends or family are around.

    They may fear being judged by others about unpleasant smells or sounds when they have a bowel motion, or how long they take to go, for example.

    Living with a gastrointestinal condition (at least four in ten Australians do) may contribute to parcopresis due to anxiety about the need to use a toilet frequently, and perceived judgment from others when doing so. Other factors, such as past negative experiences or accessibility challenges, may also play a role.

    A man in office attire holding a roll of toilet paper.
    Some people may feel uncomfortable about using the toilet at work. Motortion Films/Shutterstock

    For sufferers, anxiety can present in the form of a faster heart rate, rapid breathing, sweating, muscle tension, blushing, nausea, trembling, or a combination of these symptoms. They may experience ongoing worry about situations where they may need to use a public toilet.

    Living with parcopresis can affect multiple domains of life and quality of life overall. For example, sufferers may have difficulties relating to employment, relationships and social life. They might avoid travelling or attending certain events because of their symptoms.

    How common is parcopresis?

    We don’t really know how common parcopresis is, partly due to the difficulty of evaluating this behaviour. It’s not necessarily easy or appropriate to follow people around to track whether they use or avoid public toilets (and their reasons if they do). Also, observing individual bathroom activities may alter the person’s behaviour.

    I conducted a study to try to better understand how common parcopresis is. The study involved 714 university students. I asked participants to respond to a series of vignettes, or scenarios.

    In each vignette participants were advised they were at a local shopping centre and they needed to have a bowel motion. In the vignettes, the bathrooms (which had been recently cleaned) had configurations of either two or three toilet stalls. Each vignette differed by the configuration of stalls available.

    The rate of avoidance was just over 14% overall. But participants were more likely to avoid using the toilet when the other stalls were occupied.

    Around 10% avoided going when all toilets were available. This rose to around 25% when only the middle of three toilets was available. Men were significantly less likely to avoid going than women across all vignettes.

    For those who avoided the toilet, many either said they would go home to poo, use an available disabled toilet, or come back when the bathroom was empty.

    Parcopresis at work

    In occupational settings, the rates of anxiety about using shared bathrooms may well be higher for a few reasons.

    For example, people may feel more self-conscious about their bodily functions being heard or noticed by colleagues, compared to strangers in a public toilet.

    People may also experience guilt, shame and fear about being judged by colleagues or supervisors if they need to make extended or frequent visits to the bathroom. This may particularly apply to people with a gastrointestinal condition.

    Reducing restroom anxiety

    Using a public toilet can understandably cause some anxiety or be unpleasant. But for a small minority of people it can be a real problem, causing severe distress and affecting their ability to engage in activities of daily living.

    If doing a poo in a toilet at work or another public setting causes you anxiety, be kind to yourself. A number of strategies might help:

    • identify and challenge negative thoughts about using public toilets and remind yourself that using the bathroom is normal, and that most people are not paying attention to others in the toilets
    • try to manage stress through relaxation techniques such as deep breathing and progressive muscle relaxation, which involves tensing and relaxing different muscles around the body
    • engaging in gradual exposure can be helpful, which means visiting public toilets at different times and locations, so you can develop greater confidence in using them
    • use grounding or distraction techniques while going to the toilet. These might include listening to music, watching something on your phone, or focusing on your breathing.

    If you feel parcopresis is having a significant impact on your life, talk to your GP or a psychologist who can help identify appropriate approaches to treatment. This might include cognitive behavioural therapy.

    Simon Robert Knowles, Associate Professor and Clinical Psychologist, Swinburne University of Technology

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Cherries vs Blackberries – Which is Healthier?

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    Our Verdict

    When comparing cherries to blackberries, we picked the blackberries.

    Why?

    In terms of macros, cherries have more carbs while blackberries have more protein and fiber. The protein of course is a tiny amount and an even tinier difference, and/but it’s worth noting that the fiber isn’t, and blackberries have more than 3x the fiber. So, a win for blackberries in this category.

    In the category of vitamins, cherries have more of vitamins A, B1, B2, and B6, while blackberries have more of vitamins B3, B5, B9, C, E, K, and choline. Another win for blackberries.

    When it comes to minerals, cherries have a tiny bit more potassium, while blackberries have considerably more calcium, copper, iron, magnesium, manganese, phosphorus, selenium, and zinc. Another easy win for blackberries.

    Both fruits have abundant antioxidants, but as many are different, and comparison between them becomes more subjective than we have room for here.

    In short, enjoy either or both, but we say blackberries win overall on macro- and micronutrients!

    Want to learn more?

    You might like to read:

    Cherries’ Very Healthy Wealth Of Benefits

    Take care!

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