The Purple Parsnip’s Bioactive Brain Benefits (& more)

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This Root Might Be A Guardian Angel

Sometimes we go searching for supplements to research; sometimes supplements present themselves for examination! In this case, our attention was grabbed by a headline:

Angelica gigas extract emerges as a potential treatment for vascular disease

Angelica who?

Angelica gigas, also called the purple parsnip (amongst other names), is a flowering plant native to Korea. It has assorted medicinal properties, and in this case, it was its heart-healthy benefits that were making news:

❝Ultimately, this study presents clearly evidence that Angelica gigas extract is a promising natural product-based functional food/herbal medicine candidate for preventing or regulating hyperlipidemic cardiovascular complications❞

Source: Angelica gigas extract inhibits acetylation of eNOS via IRE1α sulfonation/RIDD-SIRT1-mediated posttranslational modification in vascular dysfunction

But it has a lot more to offer…

The root has various bioactive metabolites, but the compounds that most studies are most interested in are decursin and decursinol, for their neuroprotective and cognitive enhancement effects:

❝[C]rude extracts and isolated components from the root of A. gigas exhibited neuroprotective and cognitive enhancement effects.

Neuronal damage or death is the most important factor for many neurodegenerative diseases.

In addition, recent studies have clearly demonstrated the possible mechanisms behind the neuroprotective action of extracts/compounds from the root of A. gigas.❞

That middle paragraph there? That’s one of the main pathogenic processes of Alzheimer’s, Parkinson’s, Huntington’s, and Multiple Sclerosis.

Angelica gigas attenuates (reduces the force of) that process:

❝The published reports revealed that the extracts and isolated components from the root of A. gigas showed neuroprotective and cognitive enhancement properties through various mechanisms such as anti-apoptosis, antioxidative actions, inhibiting mRNA and protein expressions of inflammatory mediators and regulating a number of signaling pathways.

In conclusion, the A. gigas root can serve as an effective neuroprotective agent by modulating various pathophysiological processes❞

Read more: Neuroprotective and Cognitive Enhancement Potentials of Angelica gigas Nakai Root: A Review

Beyond neuroprotection & cognitive enhancement

…and also beyond its protection against vascular disease, which is what got our attention…

Angelica gigas also has antioxidant properties, anti-cancer properties, and general immune-boosting properties.

We’ve only so much room, so: those links above will take you to example studies for those things, but there are plenty more where they came from, so we’re quite confident in this one.

Of course, what has antioxidant properties is usually anti-inflammatory, anti-cancer, and anti-aging, because these things are reliant on many of the same processes as each other, with a lot of overlap.

Where can we get it?

We don’t sell it, but here’s an example product on Amazon, for your convenience

Enjoy!

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  • What Do The Different Kinds Of Fiber Do? 30 Foods That Rank Highest

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    We’ve talked before about how important fiber is:

    Why You’re Probably Not Getting Enough Fiber (And How To Fix It)

    And even how it’s arguably the most important dietary factor when it comes to avoiding heart disease:

    What Matters Most For Your Heart? Eat More (Of This) For Lower Blood Pressure ← Spoiler: it’s fiber

    And yes, that’s even when considered alongside other (also laudable) dietary interventions such as lowering intake of sodium, various kinds of saturated fat, and red meat.

    So, what should we know about fiber, aside from “aim to get nearer 40g/day instead of the US average 16g/day”?

    Soluble vs Insoluble

    The first main way that dietary fibers can be categorized is soluble vs insoluble. Part of the difference is obvious, but bear with us, because there’s more to know about each:

    • Soluble fiber dissolves (what a surprise) in water and, which part is important, forms a gel. This slows down things going through your intestines, which is important for proper digestion and absorption of nutrients (as well as avoiding diarrhea). Yes, you heard right: getting enough of the right kind of fiber helps you avoid diarrhea.
    • Insoluble fiber does not dissolve (how shocking) in water and thus mostly passes through undigested by us (some will actually be digested by gut microbes who subsist on this, and in return for us feeding them daily, they make useful chemicals for us). This kind of fiber is also critical for healthy bowel movements, because without it, constipation can ensue.

    Both kinds of fiber improve just about every metric related to blood, including improving triglycerides and improving insulin sensitivity and blood glucose levels. Thus, they help guard against various kinds of cardiovascular disease, diabetes, and metabolic disease in general. Do note that because whatever’s good for your heart/blood is good for your brain (which requires a healthy heart and bloodstream to nourish it and take away waste), likely this also has a knock-on effect against cognitive decline, but we don’t have hard science for that claim so we’re going to leave that last item as a “likely”.

    However, one thing’s for sure: if you want a healthy gut, heart, and brain, you need a good balance of soluble and insoluble fibers.

    10 of the best for soluble fiber

    FoodSoluble Fiber Type(s)Soluble Fiber (g per serving)Insoluble Fiber Type(s)Insoluble Fiber (g per serving)Total Fiber (g per serving)
    Kidney beans (1 cup cooked)Pectin, Resistant Starch1.5–2Hemicellulose, Cellulose68
    Lentils (1 cup cooked)Pectin, Resistant Starch1.5–2Cellulose67.5
    Barley (1 cup cooked)Beta-glucan3–4Hemicellulose26
    Brussels sprouts (1 cup cooked)Pectin1–1.5Cellulose, Hemicellulose23.5
    Oats (1 cup cooked)Beta-glucan2–3Cellulose13
    Apples (1 medium)Pectin1–2Cellulose, Hemicellulose23
    Carrots (1 cup raw)Pectin1–1.5Cellulose, Hemicellulose23
    Citrus fruits (orange, 1 medium)Pectin1–1.5Cellulose12.5
    Flaxseeds (2 tbsp)Mucilage, Lignin1–1.5Cellulose12.5
    Psyllium husk (1 tbsp)Mucilage3–4Trace amounts03–4

    10 of the best for insoluble fiber

    FoodSoluble Fiber Type(s)Soluble Fiber (g per serving)Insoluble Fiber Type(s)Insoluble Fiber (g per serving)Total Fiber (g per serving)
    Wheat bran (1 cup)Trace amounts0Cellulose, Lignin6–86–8
    Black beans (1 cup cooked)Pectin, Resistant Starch1.5Cellulose67.5
    Brown rice (1 cup cooked)Trace amounts0.5Hemicellulose, Lignin2–32.5–3.5
    Popcorn (3 cups popped)Trace amounts0.5Hemicellulose33.5
    Broccoli (1 cup cooked)Pectin1Cellulose, Hemicellulose45
    Green beans (1 cup cooked)Trace amounts0.5Cellulose, Hemicellulose33.5
    Sweet potatoes (1 cup cooked)Pectin1–1.5Cellulose34.5
    Whole wheat bread (1 slice)Trace amounts0.5Cellulose, Hemicellulose11.5
    Pears (1 medium)Pectin1Cellulose, Hemicellulose45
    Almonds (1 oz)Trace amounts0.5Cellulose, Hemicellulose22.5

    10 of the best for a balance of both

    FoodSoluble Fiber Type(s)Soluble Fiber (g per serving)Insoluble Fiber Type(s)Insoluble Fiber (g per serving)Total Fiber (g per serving)
    Raspberries (1 cup)Pectin1Cellulose56
    Edamame (1 cup cooked)Pectin1Cellulose56
    Chia seeds (2 tbsp)Mucilage, Pectin2–3Lignin, Cellulose35.5
    Artichokes (1 medium)Inulin1Cellulose, Hemicellulose56
    Avocado (1 medium)Pectin~2Cellulose46
    Black beans (1 cup cooked)Pectin, Resistant Starch1.5Cellulose67.5
    Quinoa (1 cup cooked)Pectin, Saponins1Cellulose, Hemicellulose34
    Spinach (1 cup cooked)Pectin0.5Cellulose, Lignin33.5
    Prunes (1/2 cup)Pectin, Sorbitol2Cellulose46
    Figs (3 medium)Pectin1Cellulose23

    You’ll notice that the above “balance” is not equal; that’s ok; we need greater quantities of insoluble than soluble anyway, so it is as well that nature provides such.

    This is the same kind of balance when we talk about “balanced hormones” (does not mean all hormones are in equal amounts; means they are in the right proportions) or “balanced microbiome” (does not mean that pathogens and friendly bacteria are in equal numbers), etc.

    Some notes on the above:

    About those fiber types, some of the most important soluble ones to aim for are:

    • Beta-glucan: found in oats and barley, it supports heart health.
    • Pectin: found in fruits like apples, citrus, and pears, it helps with cholesterol control.
    • Inulin: a type of prebiotic fiber found in artichokes.
    • Lignin: found in seeds and wheat bran, it has antioxidant properties.
    • Resistant starch: found in beans and lentils, it acts as a prebiotic for gut health.

    See also: When Is A Fiber Not A Fiber? The Food Additive You Do Want

    One fiber to rule them all

    Well, not entirely (we still need the others) but there is a best all-rounder:

    The Best Kind Of Fiber For Overall Health?

    Enjoy!

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  • Dry Needling for Meralgia Paresthetica?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s Q&A Day at 10almonds!

    Have a question or a request? We love to hear from you!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    ❝Could you address dry needling, who should administer it, and could it be a remedy for meralgia paresthetica? If not, could you speak to home-based remedies for meralgia paresthetica? Thank you?❞

    We’ll need to take a main feature some time to answer this one fully, but we will say some quick things here:

    • Dry needling, much like acupuncture, has been found to help with pain relief.
    • Meralgia paresthetica, being a neuropathy, may benefit from some things that benefit people with peripheral neuropathy, such as lion’s mane mushroom. There is definitely not research to support this hypothesis yet though (so far as we could find anyway; there is plenty to support lion’s mane helping with nerve regeneration in general, but nothing specific for meralgia paresthetica).

    Some previous articles you might enjoy meanwhile:

    Take care!

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  • The S.T.E.P.S. To A Healthier Heart

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    Stepping Into Better Heart Health

    This is Dr. Jennifer H. Mieres, FACC, FAHA, MASNC. she’s an award-winning (we counted 9 major awards) professor of cardiology, and a leading advocate for women’s heart health. This latter she’s done via >70 scientific publications, >100 research presentations at national and international conferences, 3 books so far, and 4 documentaries, including the Emmy-nominated “A Woman’s Heart”.

    What does she want us to know?

    A lot of her work is a top-down approach, working to revolutionize the field of cardiology in its application, to result in far fewer deaths annually. Which is fascinating, but unless you’re well-placed in that industry, not something too actionable as an individual (if you are well-placed in that industry, do look her up, of course).

    For the rest of us…

    Dr. Mieres’ S.T.E.P.S. to good heart health

    She wants us to do the following things:

    1) Stock your kitchen with heart health in mind

    This is tied to the third item in the list of course, but it’s a critical step not to be overlooked. It’s all very well to know “eat more fiber; eat less red meat” and so forth, but if you go to your kitchen and what’s there is not conducive to heart health, you’re just going to do the best with what’s available.

    Instead, actually buy foods that are high in fiber, and preferably, foods that you like. Not a fan of beans? Don’t buy them. Love pasta? Go wholegrain. Like leafy greens in principle, but they don’t go with what you cook? Look up some recipes, and then buy them.

    Love a beef steak? Well we won’t lie to you, that is not good for your heart, but make it a rare option—so to speak—and enjoy it mindfully (see also: mindful eating) once in a blue moon for a special occasion, rather than “I don’t know what to cook tonight, so sizzle sizzle I guess”.

    Meal planning goes a long way for this one! And if meal-planning sounds like an overwhelming project to take on, then consider trying one of the many healthy-eating meal kit services that will deliver ingredients (and their recipes) to your door—opting for a plants-forward plan, and the rest should fall into place.

    2) Take control of your activity

    Choose to move! Rather than focusing on what you can’t do (let’s say, those 5am runs, or your regularly-scheduled, irregularly attended, gym sessions), focus on what you can do, and do it.

    See also: No-Exercise Exercise!

    3) Eat for a healthier heart

    This means following through on what you did on the first step, and keeping it that way. Buying fresh fruit and veg is great, but you also have to actually eat it. Do not let the perishables perish!

    For you too, dear reader, are perishable (and would presumably like to avoid perishing).

    This item in the list may seem flippant, but actually this is about habit-forming, and without it, the whole plan will grind to a halt a few days after your first heart-health-focused shopping trip.

    See also: Where Nutrition Meets Habits!

    4) Partner with your doctor, family, and friends

    Good relationships, both professional and personal, count for a lot. Draw up a plan with your doctor; don’t just guess at when to get this or that checked—or what to do about it if the numbers aren’t to your liking.

    Partnership with your doctor goes both ways, incidentally. Read up, have opinions, discuss them! Doing so will ultimately result in better care than just going in blind and coming out with a recommendation you don’t understand and just trust (but soon forget, because you didn’t understand).

    And as for family and friends, this is partly about social factors—we tend to influence, and be influenced by, those around us. It can be tricky to be on a health kick if your partner wants take-out every night, so some manner of getting everyone on the same page is important, be it by compromise or, in an ideal world, gradually trending towards better health. But any such changes must come from a place of genuine understanding and volition, otherwise at best they won’t stick, and at worst they’ll actively create a pushback.

    Same goes for exercise as for diet—exercising together is a good way to boost commitment, especially if it’s something fun (dance classes are a fine example that many couples enjoy, for example).

    5) Sleep more, stress less, savor life

    These things matter a lot! Many people focus on cutting down salt or saturated fat, and that can be good if otherwise consumed to excess, but for most people they’re not the most decisive factors:

    Hypertension: Factors Far More Relevant Than Salt ← sleep features here!

    Stress is also a huge one, and let’s put it this way: people more often have heart attacks during a moment of excessive emotional stress—not during a moment when they had a bit too much butter on their toast.

    It’s not even just that acute stress is the trigger, it’s that chronic stress is a contributory factor that erodes the body’s ability to handle the acute stress.

    Changing this may seem “easier said than done” because often the stressors are external (e.g. work pressure, financial worries, caring for a sick relative, relationship troubles, major life change, etc), but it is possible to find peace even in the chaos of life:

    How To Manage Chronic Stress

    Want to know more from Dr. Mieres?

    You might like this book of hers, which goes into each of the above items in much more depth than we have room to here:

    Heart Smarter for Women: Six Weeks to a Healthier Heart – by Dr. Jennifer Mieres

    Enjoy!

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Related Posts

  • The Many Benefits Of Taking PQQ
  • Curing Hiccups And Headaches At Home With Actual Science

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    Quick fixes for bodily annoyances

    Do you ever find yourself desperately trying to cure hiccups, and advice on the Internet is like “breathe in through your ears while drinking vinegar upside-down through your nose”?

    If so, you’re not alone. So, today we’re going to look at some science-based approaches to dealing with common bodily annoyances.

    Hiccups

    Unfortunately, most popular advices simply don’t work, and the only near-guaranteed way to cure these is with anti-convulsive medications whose side-effects may be worse than the hiccups.

    However, before you head to the pharmacy, there is one breathing exercise that has a very simple scientific underpinning: 4:4 breathing. If you’re unfamiliar, it’s just:

    1. Breathe slowly in through your nose to a count of four
    2. Hold your breath for a count of four
    3. Breathe slowly out through your nose to a count of four
    4. Hold your breath for a count of four

    …and repeat. The slower the better. At first, your hiccups will interrupt this, but just “keep calm and carry on”.

    The reason this can work is that breathing is an autonomic function (e.g., it happens without us thinking about it) that, unlike most other autonomic functions, we can all control directly. By taking control of one, others will tend to fall into line with it.

    For example, it is normal that your heart rate will tend to slow or quicken as your breathing slows or quickens, respectively.

    Your hiccups? Autonomic function. Actually a very, very old evolutionary left-over trait, that’s only useful for protecting lungs while breathing underwater. In other words, it’s the bodily function thinks you’re a fish (or a tadpole-like amphibious creature) in the process of developing lungs. Unfortunately, because hiccuping doesn’t harm our chances of passing on our genes, it never got naturally de-selected so we still have it.

    Anyway, the bottom line is: take control of your breathing in the aspects you can directly control, and the aspects you can’t directly control will fall into line. You may need to give it some minutes, don’t give up too quickly.

    Headaches

    If you ever get a headache and you don’t have painkillers or perhaps they’re not helping or you have another reason for not wanting to take them, there’s “one quick trick” that can cure most headaches in seconds.

    First, the limitation: this will only cure headaches that have been caused by increased localized blood pressure in the forehead. However, that’s more than half of most common headaches.

    Next, how it works…

    We’re mentioning this first, because understanding how it works will give you more confidence in using it.

    Your body has a wonderful homeostatic system, which is the system by which your body maintains its “Goldilocks zones” of not too hot or cold, not to acidine or alkaline, not too hydrated or dehydrated, blood pressure not too high or too low, etc. Sometimes, however, it can get confused, and needs a nudge back to where it should be.

    One of the ways it maintains blood pressure is biofeedback from receptors in blood vessel walls, called baroreceptors. They are what it sounds like; they measure blood pressure internally.

    In certain places, there are clusters of baroreceptors in one place. And if we press on that one place, the body will think “Oh no! Super high blood pressure in this bit!” and reduce the blood pressure immediately.

    This is called the baroreflex, and that’s what you need to cure a hypertensive headache.

    So, what to do:

    With your thumb, carefully feel the upper inside corner of your eye socket. So, at the top, and about ¼ of the way out from the bridge of your nose. You should feel a groove. No, not like the Emperor’s New, but, an actual groove in your eye socket. That’s the supraorbital notch (or foramen), and it allows the supraorbital artery, veins, and nerve to run through.

    Press it firmly (you can do both sides at once, assuming you have two thumbs) for about three seconds, and then massage it gently. Repeat as necessary, but it shouldn’t take more than about three goes to have cured the headache.

    As a bonus, this is a great party trick for curing other people’s headaches, when the need arises!

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  • Resistance Is Useful! (Especially As We Get Older)

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    Resistance Is Useful!

    At 10almonds we talk a lot about the importance of regular moderate exercise (e.g. walking, gardening, housework, etc), and with good reason: getting in those minutes (at least 150 minutes per week, so, a little over 20 minutes per day, or 25 minutes per day with one day off) is the exericise most consistently linked to better general health outcomes and reduced mortality risk.

    We also often come back to mobility, because at the end of the day, being able to reach for something from a kitchen cabinet without doing oneself an injury is generally more important in life than being able to leg-press a car.

    Today though, we’re going to talk about resistance training.

    What is resistance training?

    It can be weight-lifting, or it can be bodyweight exercises. In those cases, what you’re resisting is gravity. It can also be exercises with resistance bands or machines. In all cases, it’s about building and/or maintaining strength.

    Why does it matter?

    Let’s say you’re not an athlete, soldier, or laborer, and the heaviest thing you have to pick up is a bag of groceries. Strength still matters, for two main reasons:

    • Muscle strength correlates to bone strength. You can’t build (or maintain) strong muscles on weak bones, so if you take care of your muscles, then your body will keep your bones strong too.
      • That’s assuming you have a good diet as well—but today’s not about that. If you’d like to know more about eating for bone health though, do check out this previous article about that!
    • Muscle strength correlates to balance and stability. You can’t keep yourself from falling over if you are physically frail.

    Both of those things matter, because falls and fractures often have terrible health outcomes (e.g., slower recovery and more complications) the older we get. So, we want to:

    • Ideally, not fall in the first place
    • If we do fall, have robust bones

    See also: Effects of Resistance Exercise on Bone Health

    How much should we do?

    Let’s go to the Journal of Strength and Conditioning Research on this one:

    ❝There is strong evidence to support the benefits of resistance exercise for countering many age-related processes of sarcopenia, muscle weakness, mobility loss, chronic disease, disability, and even premature mortality.

    In addition, this Position Statement provides specific evidence-based practice recommendations to aid in the implementation of resistance exercise programs for healthy older adults and those with special considerations.

    While there are instances where low-intensity, low-volume programs are appropriate (i.e., beginning programs for individuals with frailty or CVDs), the greatest benefits are possible with progression to moderate to higher intensity programs.❞

    ~ Fragala et al

    Read the statement in full:

    Resistance Training for Older Adults: Position Statement From the National Strength and Conditioning Association

    There’s a lot of science there and it’s well worth reading if you have the time. It’s particularly good at delineating how much is not enough vs how much is too much, and the extent to which we should (or shouldn’t) train to exhaustion.

    If you don’t fancy that, though, and/or just want to start with something accessible and work your way up, the below is a very good (and also evidence-based) start-up plan:

    Healthline’s Exercise Plan For Seniors—For Strength, Balance, & Flexibility

    (it has a weekly planner, step-by-step guides to the exercises, and very clear illustrative animations of each)

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  • Toasted Chick’n Mango Tacos

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    Tacos aren’t generally held up as the world’s healthiest food, but they can be! There’s so much going on in this dish today, healthwise, in a good way, that it’s hard to know where to start. But suffice it to say, these tacos are great for your gut, heart, blood sugars, and more.

    You will need

    For the chickpeas:

    • 1 can chickpeas, drained
    • 1 tbsp ras el-hanout*
    • 1 tsp red pepper flakes
    • ½ tsp MSG or 1 tsp low-sodium salt
    • Extra virgin olive oil

    *You can easily make this yourself; following our recipe (linked above in the ingredients list) will be better than buying it ready-made, and if you have strong feelings about any of the ingredients, you can adjust per your preference.

    For the tahini sauce:

    • ⅓ cup tahini
    • 2 tbsp apple cider vinegar
    • 2 tbsp finely chopped fresh dill
    • ¼ bulb garlic, minced
    • 1 tsp red pepper flakes
    • ½ tsp black pepper, coarse ground

    It may seem like salt is conspicuous by its absence, but there is already enough in the chickpeas component; you do not want to overwhelm the dish. Trust us that enjoying these things together will be well-balanced and delicious as written.

    For the mango relish:

    • ½ mango, pitted, peeled, and cubed
    • 2 tsp apple cider vinegar
    • 2 tsp cilantro, finely chopped (substitute with parsley if you have the “cilantro tastes like soap” gene)
    • 1 tsp red pepper flakes

    For building the taco:

    • Soft corn tortillas
    • Handful of arugula
    • 1 avocado, pitted, peeled, and sliced
    • ½ red onion, sliced

    Method

    (we suggest you read everything at least once before doing anything)

    1) Heat a sauté pan with a little olive oil in; add the chickpeas and then the rest of the ingredients from the chickpea section; cook for about 5 minutes, stirring frequently, and set aside.

    2) Combine the tahini sauce ingredients in a small bowl, stirring in ¼ cup water, and set aside.

    3) Combine the mango relish ingredients in a separate small bowl, and set aside. You can eat the other half of the mango if you like.

    4) Lightly toast the tortillas in a dry skillet, or using a grill.

    5) Assemble the tacos; we recommend the order: tortillas, arugula, avocado slices, chickpeas, mango relish, red onion slices, tahini sauce.

    Enjoy!

    Want to learn more?

    For those interested in some of the science of what we have going on today:

    Take care!

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