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Younger For Life – by Dr. Anthony Youn
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We’ve reviewed anti-aging books before, so what makes this one different? Mostly, it’s the very practical focus.
Which is not to say there’s not also good science in here; there is. But the focus is on what everything means for the reader, not what happened with a certain cohort of lab mice. Instead, he looks at the causes of aging, the process of aging, and what interventions to implement to address those, and reverse many of them.
Some parts are more general lifestyle interventions that 10almonds readers will know well already, but other parts are very specific advices, protocols, and regimes; in particular his skincare section is well worth reading. As for nutrition, there’s even a respectable recipes section, so this book does have it all!
The final section of the book is dedicated to plastic surgeries (the author is a plastic surgeon who believes that most people should not need those, and would do well to stick to the advices in the rest of the book). We suspect this last part of the book will be of least interest to 10almonds readers.
Bottom line: if you’re of the view that getting older should come with as little as possible physical deterioration along the way, then this book can help a lot with that.
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The Power of Self-Care – by Dr. Sunil Kumar
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First, what this book is mostly not about: bubble baths and scented candles. We say “mostly”, because stress management is an important aspect given worthy treatment in this book, but there is more emphasis on evidence-based interventions and thus Dr. Kumar is readier to prescribe nature walks and meditation, than product-based pampering sessions.
As is made clear in the subtitle “Transforming Heart Health with Lifestyle Medicine”, the focus is on heart health throughout, but as 10almonds readers know, “what’s good for your heart is good for your brain” is a truism that indeed holds true here too.
Dr. Kumar also gives nutritional tweaks to optimize heart health, and includes a selection of heart-healthy recipes, too. And exercise? Yes, customizable exercise plans, even. And a plan for getting sleep into order if perchance it has got a bit out of hand (most people get less sleep than necessary for maintenance of good health), and he even delves into “social prescribing”, that is to say, making sure that one’s social connectedness does not get neglected—without letting it, conversely, take over too much of one’s life (done badly, social connectedness can be a big source of unmanaged stress).
Perhaps the most value of this book comes from its 10-week self-care plan (again, with a focus on heart health), basically taking the reader by the hand for long enough that, after those 10 weeks, habits should be quite well-ingrained.
A strong idea throughout is that the things we take up should be sustainable, because well, a heart is for life, not just for a weekend retreat.
Bottom line: if you’d like to improve your heart health in a way that feels like self-care rather than an undue amount of work, then this is the book for you.
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Citicoline: Better Than Dietary Choline?
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Citicoline: Better Than Dietary Choline?
Citicoline, also known as cytidine diphosphate-choline (or CDP-Choline, to its friends, or cytidine 5′-diphosphocholine if it wants to get fancy) is a dietary supplement that the stomach can metabolize easily for all the brain’s choline needs. What are those needs?
Choline is an essential nutrient. We technically can synthesize it, but only in minute amounts, far less than we need. Choline is a key part of the neurotransmitter acetylcholine, as well as having other functions in other parts of the body.
As for citicoline specifically… it appears to do the job better than dietary sources of choline:
❝Intriguing data, showing that on a molar mass basis citicoline is significantly less toxic than choline, are also analyzed.
It is hypothesized that, compared to choline moiety in other dietary sources such as phosphatidylcholine, choline in citicoline is less prone to conversion to trimethylamine (TMA) and its putative atherogenic N-oxide (TMAO).
Epidemiological studies have suggested that choline supplementation may improve cognitive performance, and for this application citicoline may be safer and more efficacious.❞
Source: Citicoline: A Superior Form of Choline?
Great! What does it do?
What doesn’t it do? When it comes to cognitive function, anyway, citicoline covers a lot of bases.
Short version: it improves just about every way a brain’s healthy functions can be clinically measured. From cognitive improvements in all manner of tests (far beyond just “improves memory” etc; also focus, alertness, verbal fluency, logic, computation, and more), to purely neurological things like curing tinnitus (!), alleviating mobility disorders, and undoing alcohol-related damage.
One of the reasons it’s so wide in its applications, is that it has a knock-on effect to other systems in the brain, including the dopaminergic system.
Long version: Citicoline: pharmacological and clinical review, 2022 update
(if you don’t want to sit down for a long read, we recommend skimming to the charts and figures, which are very elucidating even alone)
Spotlight study in memory
For a quick-reading example of how it helps memory specifically:
Keeping dementia at bay
For many older people looking to improve memory, it’s less a matter of wanting to perform impressive feats of memory, and more a matter of wanting to keep a sharp memory throughout our later years.
Dr. Maria Bonvicini et al. looked into this:
❝We selected seven studies including patients with mild cognitive impairment, Alzheimer’s disease or post-stroke dementia
All the studies showed a positive effect of citicoline on cognitive functions. Six studies could be included in the meta-analysis.
Overall, citicoline improved cognitive status, with pooled standardized mean differences ranging from 0.56 (95% CI: 0.37-0.75) to 1.57 (95% CI: 0.77-2.37) in different sensitivity analyses❞
The researchers concluded “yes”, and yet, called for more studies, and of higher quality. In many such studies, the heterogeneity of the subjects (often, residents of nursing homes) can be as much a problem (unclear whether the results will be applicable to other people in different situations) as it is a strength (fewer confounding variables).
Another team looked at 47 pre-existing reviews, and concluded:
❝The review found that citicoline has been proven to be a useful compound in preventing dementia progression.
Citicoline has a wide range of effects and could be an essential substance in the treatment of many neurological diseases.
Its positive impact on learning and cognitive functions among the healthy population is also worth noting.❞
Source: Application of Citicoline in Neurological Disorders: A Systematic Review
The dopamine bonus
Remember how we said that citicoline has a knock-on effect on other systems, including the dopaminergic system? This means that it’s been studied (and found meritorious) for alleviating symptoms of Parkinson’s disease:
❝Patients with Parkinson’s disease who were taking citicoline had significant improvement in rigidity, akinesia, tremor, handwriting, and speech.
Citicoline allowed effective reduction of levodopa by up to 50%.
Significant improvement in cognitive status evaluation was also noted with citicoline adjunctive therapy.❞
Source: Citicoline as Adjuvant Therapy in Parkinson’s Disease: A Systematic Review
Where to get it?
We don’t sell it, but here’s an example product on Amazon, for your convenience
Enjoy!
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Better Sex Through Mindfulness – by Dr. Lori Brotto
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Female sexuality is such a taboo topic that, if one searches for (ob/gyn professor, women’s health research director, and psychologist) Dr. Brotto’s book on Google or Amazon, it suggests only “lori brotto mindfulness book”. So, for those brave enough to read a book that would have shocked Victorians, what does this one contain?
The focus is on, as the title suggests, better sex, by and for women. That said, it’s mostly because typically women are more likely to experience the problems described in the book; it’s nothing actually intrinsic to womanhood. A man with the same problems could read this book and benefit just the same.
While the book covers many possible problems between the sheets, the overarching theme is problems of the mind, such as:
- Not getting into the mood in the first place
- Losing the mood quickly and easily, such as by becoming distracted
- Difficulty achieving orgasm even when mechanically everything’s delightful
- Physical discomfort creating a barrier to enjoyment
…and yes, that last one is in part mind-stuff too! Though Dr. Brotto isn’t arguing that mindfulness is a panacea, just an incredibly useful tool. And, it’s one she not only explains very well, but also explains from the position of a wealth of scientific evidence… Enough so, that we see a one-star Amazon reviewer from Canada complained that it was too well-referenced! For us, though, it’s what we like to see.
Good science, presented clearly and usefully, giving practical tips that improve people’s lives.
Bottom line: if you’ve ever lost the mood because you got distracted into thinking about taxes or that meeting on Tuesday, this is the book for you.
Click here to check out Better Sex Through Mindfulness—you can thank us later!
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Genital herpes is on the rise. Here’s what to know about this common infection
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The World Health Organization (WHO) recently released new estimates suggesting around 846 million people aged between 15 and 49 live with a genital herpes infection.
That’s equivalent to one in every five people from that age group.
At least one person each second (42 million people annually) contracts a new genital herpes infection.
So what is genital herpes, and are cases on the rise? Here’s what to know about this common infection.
Peakstock/Shutterstock First, what causes genital herpes?
Genital herpes is a sexually transmitted infection (STI) caused by the herpes simplex virus, which also causes cold sores.
There are two types of herpes simplex virus, HSV-1 and HSV-2 (and it’s possible to be infected by both at the same time).
HSV-1 most commonly spreads through oral contact such as kissing or sharing infected objects such as lip balm, cups or utensils, and presents as cold sores (or oral herpes) around the mouth. But it can also be sexually transmitted to cause a genital herpes infection.
An estimated 3.8 billion people under the age of 50 (64%) globally have HSV-1.
HSV-2 is less prevalent, but almost always causes a genital herpes infection. Some 520 million people aged 15–49 (13%) worldwide are believed to have HSV-2.
The initial episode of genital herpes can be quite painful, with blisters, ulcers and peeling skin around the genitals over 7–10 days.
Not all people have severe (or any) initial symptoms. This means a person might not know they have been infected with a herpes virus.
Herpes is a lifelong infection, which means once you contract the virus, you have it forever. After an initial episode, subsequent episodes can occur, but are usually less painful or even symptom free.
Both oral and genital herpes are particularly easy to spread when you have active lesions (cold sores or genital ulcers). But even with no symptoms, herpes can still be spread to a partner.
And although relatively rare, oral herpes can be transmitted to the genital area, and genital herpes can be transmitted to the mouth through oral sex.
If an expectant mother exhibits a genital herpes infection close to childbirth, there are risks to the baby. A herpes infection can be very serious in a baby, and the younger the infant, the more vulnerable they are. This is also one reason why you should avoid kissing a baby on the mouth.
Changing trends
WHO’s recent figures brought together data from around the world to estimate the prevalence of genital herpes in 2020, compared with previous estimates in 2012 and 2016.
This data shows no significant difference in the prevalence of genital herpes caused by HSV-2 since 2016, but does highlight increases in genital herpes infections caused by HSV-1.
The estimated number of genital HSV-1 infections globally was nearly twice as high in 2020 compared with 2016 (376 million compared with 192 million).
A 2022 study looking at Australia, New Zealand and Canada found more than 60% of genital herpes infections are still caused by HSV-2. But this is declining by about 2% each year while new genital infections that result from HSV-1 are rising.
Genital herpes can be quite painful, presenting as sores and lesions that in severe cases, may take up to a month to fully heal. Christian Moro There’s no simple fix, but safe sex is important
Genital herpes causes a substantial disease burden and economic cost to health-care services.
With such a large proportion of the world’s population infected with HSV-1, evidence this virus is increasingly causing genital herpes is concerning.
There’s no cure for genital herpes, but some medications, such as antivirals, can help reduce the amount of virus present in the system. While this won’t kill it completely, it helps to prevent symptomatic genital herpes recurrences, improve quality of life, and minimise the risk of transmission.
To prevent the spread of genital herpes and other STIs, practise safe sex, particularly if you’re not sure of your partner’s sexual health. You need to use a barrier method such as condoms to protect against STIs (a contraceptive such as the pill won’t work). This includes during oral sex.
As herpes is now so common, testing is not usually included as part of a regular sexual health check-up, except for in specific circumstances such as during pregnancy or severe episodes.
So it’s wise not to let your guard down, even if your partner insists they have received the all-clear from a recent check-up.
If there are herpes lesions present around the genitals, avoid sex entirely. Even condoms are not fully effective at these times, as exposed areas can still transmit the infection.
Practising safe sex can help prevent the spread of herpes. cottonbro studio/Pexels Immune health
If you are infected with HSV-1 or HSV-2 it’s more likely symptoms will appear when you’re stressed, tired or overwhelmed. During these times, our immune system may not be as functional, and dormant viruses such as herpes can start to develop quickly in our bodies.
To reduce the risk of recurrent herpes infections, try to eat healthily, get at least seven hours of sleep each night if possible, and look out for when your body may be telling you to take a step back and relax. This self-care can go a long way towards keeping latent viruses at bay.
While the prevalence has increased significantly in recent years, we have not lost the war on genital herpes just yet. Safe sexual practices, education and awareness can help reduce its spread, and the stigma around it.
If you have personal concerns, you should discuss them with a medical professional.
Christian Moro, Associate Professor of Science & Medicine, Bond University and Charlotte Phelps, Senior Teaching Fellow in Medicine, Bond University
This article is republished from The Conversation under a Creative Commons license. Read the original article.
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Top 10 Unhealthy Foods: How Many Do You Eat?
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The items on this list won’t come as a shocking surprise to you, but it can be a good opportunity to do a quick tally and see how many of these have snuck into your diet:
The things that take away health instead of adding it
Without further ado, they are…
- Alcohol: not only is it high in empty calories, but also it’s bad for pretty much everything, especially increasing the risks of liver disease, high blood pressure, and stroke.
- Processed snacks: low in nutrition; contain unhealthy fats, refined sugars, and artificial additives that often aren’t great.
- Potato chips: get their own category for being especially high in fat, sodium, and empty calories; contribute to heart disease and weight gain.
- Processed cheese: some kinds of cheese are gut-healthy in moderation, but this isn’t. Instead, it’s just loaded with saturated fats, sodium, and sugars, and is pretty much heart disease in a slice.
- Donuts: deep-fried, sugary, and made with refined flour; cause blood sugar spikes and crashes, and what’s bad for your blood sugars is bad for almost everything else.
- French fries & similar deep-fried foods: high in saturated fats and sodium; contribute to obesity and heart issues, are not great for blood sugars either.
- White bread: made with refined flour; cause blood sugar spikes and metabolic woes.
- Sodas: high in sugar or artificial sweeteners; can easily lead to weight gain, diabetes, and tooth decay.
- Processed meats: high in calories and salt; strongly associated with heart disease and cancer.
- Hot dogs & fast food burgers: get their own category for being the absolute worst of the above-mentioned processed meats.
This writer scored: no / rarely / no / no / no / rarely / rarely / rarely / no / no
How about you?
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Which B Vitamins? It Makes A Difference
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Everyone knows “B vitamins are for energy!” and that is definitely a theme, but there’s a lot more to it than that, and in some cases, there are big mistakes that people make when it comes to supplementing their diet.
First, let’s do a quick overview of what each of the B vitamins do, by number, and putting names to them:
B1 (Thiamine)
- Function: helps convert carbohydrates into energy, supports nerve function
- Forms: thiamine hydrochloride, thiamine mononitrate, benfotiamine (fat-soluble form)
- Example foods: lentils, sunflower seeds
B2 (Riboflavin)
- Function: supports energy production, skin health, and eye function, turns your pee fluorescent yellow (the latter is really only if you consume exciting amounts of it; this will usually occur from supplementation, not from normal diet)
- Forms: riboflavin, riboflavin-5’-phosphate
- Example foods: almonds, mushrooms
B3 (Niacin)
- Function: aids metabolism, supports skin, nerves, and cholesterol levels
- Forms: niacin (nicotinic acid), niacinamide (nicotinamide), inositol hexanicotinate (flush-free niacin)
- Example foods: whole grains, peanuts (literally the best nut for this)
B5 (Pantothenic Acid)
- Function: essential for fatty acid metabolism and hormone production
- Forms: pantothenic acid, calcium pantothenate, panthenol (alcohol form!)
- Example foods: it’s in pretty much everything (hence the name); it’s almost impossible to be deficient in this vitamin unless you are literally starving
B6 (Pyridoxine)
- Function: needed for red blood cell production, supports brain function, as well as specifically being a part of neurotransmitter production (including dopamine and serotonin, despite them being made in different places—the brain and the gut, respectively),
- Forms: pyridoxine hydrochloride, pyridoxal-5’-phosphate (active form)
- Example foods: bananas, potatoes
B7 (Biotin)
- Function: helps with fatty acid synthesis, skin, hair, and nail health
- Forms: d-biotin, biotinylated compounds of various kinds
- Example foods: fava beans, walnuts
B9 (Folate/Folic Acid)
- Function: crucial for DNA synthesis, cell division, and fetal development
- Forms: folic acid, folinic acid, 5-methyltetrahydrofolate (5-MTHF, active form)
- Example foods: chickpeas, spinach ← we only mentioned one leafy green here for fairness, but leafy greens in general are great sources of vitamin B9, hence the name, from the Latin “folium”, meaning leaf.
B12 (Cobalamin)
- Function: supports red blood cell formation, nerve function, and DNA synthesis
- Forms: cyanocobalamin, methylcobalamin (active), hydroxocobalamin (active), adenosylcobalamin (active)
- Example foods: nutritional yeast, nori
You may be wondering: what about vitamins B4, B8, B10, and B11? Those are now vacant spots, that once contained things that are no longer considered vitamins.
Three Critical Vitamin B Mistakes That May Be Sabotaging Your Health
Some mistakes that people make include:
Not supplementing when necessary
This occurs most often after midlife, especially in women, and the most common deficiencies are B1, B9, and B12.
See also: These Signs Often Mean These Nutrient Deficiencies (Do You Have Any?)
While it’s tempting to think “if I have a good balanced diet, I won’t need…” but the fact is sometimes our diet isn’t as nutrient dense as we hope—often through no fault of our own! But many modern farming methods prioritize yield over nutritional value, and that can result in plants and animals that do not have the nutritional qualities they “should”.
We wrote about this a while back, weighing up the “supplementation vs diet alone” dilemma:
Does Our Diet Need A Little Help? ← this also has a very useful chart of which vitamins people usually get too little or too much of. Note however that the statement of marginally excessive folate is slightly misleading, as the data pool contains men and women aged 18–65, while B9 is mostly needed more by women, and especially around childbirth or menopause, so B9 is actually a very common deficiency, but here it’s being balanced out lots of men getting too much (because every multivitamin has it).
Supplementing to excess
Most B vitamins have a very high maximum tolerable dose, because (with the exception of where we marked otherwise) they are water-soluble, which means that if you take more than you need, you’ll just pee it out later. Hence the famous fluorescence, for example.
However, the fat soluble form of vitamin B1 is harder to get in and harder to get out.
As for the others, problems usually only occur if you take enough to cause toxicity, faster than you pee it out. In other words, go easy on those Berocca drinks!
Nevertheless, there are other problems that can arise:
Vitamin B6 is essential—but too much can be toxic. Here’s what to know to stay safe ← tl;dr: there are issues with it causing peripheral neuropathy at doses over 10mg (the safe dose is disputed, so we’re mentioning the lowest safe dose here, but you can read about the others in the article)
Getting forms that don’t work so well
Those different forms we listed? They are not all created equal! For example:
- Folic acid is cheap; unfortunately, it’s not absorbed or used well
- Cyanocobalamin is cheap; unfortunately, it’s not absorbed or used well
Let us quote a recent book review of ours:
❝Rather, the most common forms of vitamins B9 and B12 provided in supplements are folic acid and cyanocobalamin, respectively, which as he demonstrates with extensive research to back up his claims, cannot be easily absorbed or used especially well.
About those vitamers: a vitamer is simply a form of a vitamin—most vitamins we need can arrive in a variety of forms. In the case of vitamins B9 and B12, he advocates for ditching vitamers folic acid and cyanocobalamin, cheap as they are, and springing for bioactive vitamers L-methylfolate, methylcobalamin, and adenosylcobalamin.
He also discusses (again, just as well-evidenced as the above things) why we might struggle to get enough from our diet after a certain age. For example, if trying to get these vitamins from meat, 50% of people over 50 cannot manufacture enough stomach acid to break down that protein to release the vitamins.
And as for methyl-B12 vitamers, you might expect you can get those from meat, and technically you can, but they don’t occur in all animals, just in one kind of animal. Specifically, the kind that has the largest brain-to-body ratio. However, eating the meat of this animal can result in protein folding errors in general and Creutzfeldt–Jakob disease in particular, so the author does not recommend eating humans, however nutritionally convenient that would be.
All this means that supplementation after a certain age really can be a sensible way to do it—but do it wisely, and pick the right vitamers.❞
You can read that review in full here: Your Vitamins are Obsolete: The Vitamer Revolution – by Dr. Sheldon Zablow
Want to try those latter two?
We don’t sell them, but here for your convenience are example products on Amazon:
L-methylfolate (active form of vitamin B9)
Methylcobalamin, adenosylcobalamin, & hydroxocobalamin (active forms of vitamin B12)
Take care!
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