Why Women Especially Should Watch Out For COPD

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We’ve written before about Chronic Obstructive Pulmonary Disease (COPD), which is a rising killer of Americans, and affects an estimated 9% of the population. Even accounting for 10almonds readers probably being healthier than average, we’d bet this means it still affects at least 1 in 20 readers.

If you’re thinking “good thing that’s not me”, then do bear in mind that an estimated 50% of people with COPD don’t know it.

See also: Why Chronic Obstructive Pulmonary Disease (COPD) Is More Likely Than You Think ← you can also see the symptoms of it there, and you’ll see why it often escapes notice for quite a while, sometimes years at first.

Much like how in a house with a carbon monoxide leak, the inhabitants get less and less oxygen, but usually don’t notice it.

Gender disparity

Recent research has shown that women are around 50% more likely than men to develop COPD, even if they have never smoked or smoked less.

This is very reminiscent of what we talked about recently for lung cancer, here: Why Lung Cancer Is On The Rise Even In Women Who’ve Never Smoked

Historically, it was assumed that women got it more simply because we were more vulnerable to cigarette smoke, but these statistics show that can’t be the reason.

You may be wondering about the validity of the study, the size etc, and: data from the 2020 US National Health Interview Survey was used, involving over 23,000 adults aged 40+.

In this study, women reported lower use of cigarettes, cigars, pipes, and smokeless tobacco, although similar vaping rates to men, and yet COPD prevalence was higher in women (8%) than in men (6.5%).

It’s worth noting also that of the people with COPD, 26.5% of women had never smoked vs 14% of men.

Even after adjusting for other factors, female gender was linked to a 47% higher COPD risk.

What this tells us: tobacco susceptibility alone doesn’t explain the gender gap in COPD risk.

What remains a mystery: where this gender gap is actually coming from.

The researchers also note:

❝Studies have shown that primary care physicians are less likely to consider COPD in women compared with men presenting with similar symptoms, that use of spirometry can correct this bias, but that unfortunately women undergo spirometry testing less frequently than men❞

…which is unfortunately a very familiar song when it comes to things that predominantly or disproportionately affect women.

You can read the study paper itself in its entirety here:

Gender, tobacco and chronic obstructive pulmonary disease: analysis of the 2020 National Health Interview Survey

(the 2020 date in the paper title makes it seem like it’s not new research, but we promise it is; this was published just two days ago at time of writing, on the 8th of May 2025, and represents a very comprehensive analysis of the pre-COVID data)

Want to learn more?

For practical advice, check out:

Seven Things To Do For Good Lung Health!

And for a very in-depth treatment of the topic, you might like this book we reviewed:

Triple Life Threat – by Donald R. Lyman

Take care!

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  • What causes depression? What we know, don’t know and suspect
    Depression is a complex and deeply personal experience. While almost everyone has periods of sadness, low mood or grief, depression is different. Major depressive disorder is persistent, interferes with day-to-day activities, and can affect work, life and relationships. One in five people will experience depression in their lifetime. Women are nearly twice as likely as…

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  • Superfood-Stuffed Squash

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    This stuffed squash recipe is packed with so many nutrient-dense ingredients, yet it feels delightfully decadent—a great recipe to have up your sleeve ready for fall.

    You will need

    • 1 large or two medium butternut squashes, halved lengthways and seeds removed (keep them; they are full of nutrients! You can sprout them, or dry them to use them at your leisure), along with some of the flesh from the central part above where the seeds are, so that there is room for stuffing
    • 2 cups low-sodium vegetable stock
    • 1 cup wild rice, rinsed
    • 1 medium onion, finely chopped
    • ½ cup walnuts, roughly chopped
    • ½ cup dried cranberries goji berries ← why goji berries? They have even more healthful properties than cranberries, and cranberries are hard to buy without so much added sugar that the ingredients list looks like “cranberries (51%), sugar (39%), vegetable oil (10%)”, whereas when buying goji berries, the ingredients list says “goji berries”, and they do the same culinary job.
    • ¼ cup pine nuts
    • ½ bulb garlic, minced
    • 1 tbsp dried thyme or 2 tsp fresh thyme, destalked
    • 1 tbsp dried rosemary or 2 tsp fresh rosemary, destalked
    • 1 generous handful fresh parsley, chopped
    • 1 tbsp chia seeds
    • 1 tbsp nutritional yeast
    • 1 tbsp black pepper, coarse ground
    • ½ tsp MSG or 1 tsp low-sodium salt
    • Extra virgin olive oil, for brushing and frying
    • Aged balsamic vinegar, to serve (failing this, make a balsamic vinegar reduction and use that; it should have a thicker texture but still taste acidic and not too sweet; the thickness should come from the higher concentration of grape must and its natural sugars; no need to add sugar)

    Method

    (we suggest you read everything at least once before doing anything)

    1) Preheat the oven to 400°F / 200°C.

    2) Brush the cut sides of the squash with olive oil; sprinkle with a pinch of MSG/salt and a little black pepper (grind it directly over the squash if you are using a grinder; hold the grinder high though so that it distributes evenly—waiters in restaurants aren’t just being dramatic when they do that with pepper or Parmesan or such)

    3) Arrange them cut-sides-down on a baking tray lined with baking paper, and roast for at least 30 minutes or until tender.

    4) While that is roasting, add the chia seeds to the wild rice, and cook them in the low-sodium vegetable stock, using a rice cooker if available. It should take about the same length of time, but if the rice is done first, set it aside, and if the squash is done first, turn the oven down low to keep it warm.

    5) Heat some oil in a sauté pan (not a skillet without high sides; we’re going to need space in a bit), and fry the chopped onion until translucent and soft. We could say “about 5 minutes” but honestly it depends on your pan as well as the heat and other factors.

    6) Add the seasonings (herbs, garlic, black pepper, MSG/salt, nooch), and cook for a further 2 minutes, stirring thoroughly to distribute evenly.

    7) Add the rice, berries, and nuts, cooking for a further 2 minutes, stirring constantly, ensuring everything is heated evenly.

    8) Remove the squash halves from the oven, turn them over, and spoon the mixture we just made into them, filling generously.

    9) Drizzle a lashing of the aged balsamic vinegar (or balsamic vinegar reduction), to serve.

    Enjoy!

    Want to learn more?

    For those interested in some of the science of what we have going on today:

    Take care!

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  • How To Set Anxiety Aside

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    How To Set Anxiety Aside

    We’ve talked previously about how to use the “release” method to stop your racing mind.

    That’s a powerful technique, but sometimes we need to be calm enough to use it. So first…

    Breathe

    Obviously. But, don’t underestimate the immediate power of focusing on your breath, even just for a moment.

    There are many popular breathing exercises, but here’s one of the simplest and most effective, “4–4 breathing”:

    • Breathe in for a count of four
    • Hold for a count four
    • Breathe out for a count of four
    • Hold for a count of four
    • Repeat

    Depending on your lung capacity and what you’re used to, it may be that you need to count more quickly or slowly to make it feel right. Experiment with what feels comfortable for you, but the general goal should breathing deeply and slowly.

    Identify the thing that’s causing you anxiety

    We’ve also talked previously about how to use the RAIN technique to manage difficult emotions, and that’s good for handling anxiety too.

    Another powerful tool is journaling.

    Read: How To Use Journaling to Challenge Anxious Thoughts

    If you don’t want to use any of those (very effective!) methods, that’s fine too—journaling isn’t for everyone.

    You can leverage some of the same benefits by simply voicing your worries, even to yourself:

    There’s an old folk tradition of “worry dolls”; these are tiny little dolls so small they can be kept in a pocket-size drawstring purse. Last thing at night, the user whispers their worries to the dolls and puts them back in their bag, where they will work on the person’s problem overnight.

    We’re a health and productivity newsletter, not a dealer of magic and spells, but you can see how it works, right? It gets the worries out of one’s head, and brings about a helpful placebo effect too.

    Focus on what you can control

    • Most of what you worry about will not happen.
    • Some of what you worry about may happen.
    • Worrying about it will not help.

    In fact, in some cases it may bring about what you fear, by means of the nocebo effect (like the placebo effect, but bad). Additionally, worrying drains your body and makes you less able to deal with whatever life does throw at you.

    So while “don’t worry; be happy” may seem a flippant attitude, sometimes it can be best. However, don’t forget the other important part, which is actually focusing on what you can control.

    • You can’t control whether your car will need expensive maintenance…
      • …but you can control whether you budget for it.
    • You can’t control whether your social event will go well or ill…
      • …but you can control how you carry yourself.
    • You can’t control whether your loved one’s health will get better or worse…
      • …but you can control how you’re there for them, and you can help them take what sensible precautions they may.

    …and so forth.

    Look after your body as well!

    Your body and mind are deeply reliant on each other. In this case, just as anxiety can drain your body’s resources, keeping your body well-nourished, well-exercised, and well-rested and can help fortify you against anxiety. For example, when it comes to diet, exercise, and sleep:

    Don’t know where to start? How about the scientifically well-researched, evidence-based, 7-minute workout?

    Check Out the Seven Minute Workout App (Android and iOS

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  • Viruses, Bacteria, Allergens: One Nasal Spray To Stop Them All

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    …and in the airways, fight them!

    Scientists unveil a “universal vaccine”

    Vaccines save millions of lives every year:

    Since vaccines are not without their popular misunderstanders, we have written a little about that, here: Vaccine Mythbusting

    However, they have limitations. Most notably, because they work by showing your immune system a recognizable piece of a specific pathogen, such as the spike protein of COVID, this runs into difficulties when viruses mutate, so surface antigens change, which is why COVID boosters, annual flu shots, and similar vaccines sometimes need updating.

    Researchers (Dr. Mengyun Hu et al.) found a way to create a broad protection against many respiratory threats.

    How it does that, in technical terms: the formulation GLA-3M-052-LS+OVA combines toll-like receptor 4 and 7/8 ligands with ovalbumin to recruit memory CD4+ and CD8+ T cells into your lungs and keep alveolar macrophages in a heightened defensive state.

    Translating from sciencese: instead of targeting a specific antigen from one pathogen, the nasal spray boosts your lungs’ integrated innate and adaptive immune responses to provide broad protection.

    Dr. Hu (what a cool name) and her team will be doing human trials soon, but the results so far from mouse studies are very promising:

    • Against viruses: vaccinated mice enjoyed a 700-fold reduction in lung viral levels after SARS-CoV-2 exposure, avoided severe weight loss, and all survived*.
    • Against bacteria: vaccinated mice were also protected for about 3 months against Staphylococcus aureus and Acinetobacter baumannii, both common causes of hospital-acquired pneumonia.
    • Against allergies: when exposed to house dust mite allergens, vaccinated mice developed a much weaker Th2 response (which in this context, is good) and maintained clear airways compared with unvaccinated mice.

    *This is a big difference from what happened in unvaccinated mice, because while the unvaccinated mice had initially healthy immune systems, those unvaccinated immune systems had no instructions about what to do, and thus:

    ❝The immune system becomes so ready and so alert that it can launch the typical adaptive responses—virus-specific T cells and antibodies—in as little as three days, compared with about 2 weeks in unvaccinated mice❞

    ~ Dr. Violetta Horton, professor of microbiology and immunology, and colleague of Dr. Hu collaborating on this study

    If it’s successful in human trials:

    • It’s expected to require just two nasal doses
    • It could replace multiple seasonal respiratory vaccines
    • It should seriously boost rapid protection during future pandemics

    You can find the study itself, here: Mucosal vaccination in mice provides protection from diverse respiratory threats

    Want to do more meanwhile?

    You might want to check out: Beyond Supplements: The Real Immune-Boosters! ← most people don’t know these things and the huge difference they make

    And for that matter: Why Some People Get Sick More (And How To Not Be One Of Them) ← for a very prophylactic approach

    Take care!

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  • Children can be more vulnerable in the heat. Here’s how to protect them this summer

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    Extreme heat is increasingly common in Australia and around the world and besides making us uncomfortable, it can harm our health. For example, exposure to extreme heat can exacerbate existing medical conditions, or cause problems such as heat stroke.

    Due to a combination of physiology and behaviour, children are potentially more vulnerable to severe heat-related illness such as heat stroke or heat exhaustion.

    But these are not the only heat-related health issues children might experience on a very hot day. In a new study, we looked at emergency department (ED) visits and unplanned hospital admissions among children in New South Wales on heatwave days.

    We found a significant increase in children attending hospital compared to milder days – with a range of health issues.

    maxim ibragimov/Shutterstock

    Why are children more vulnerable in the heat?

    Sweating is the main way we lose heat from our bodies and cool down.

    Children have a greater skin surface area to body mass ratio, which can be an advantage for sweating – they can lose more heat through evaporation for a given body mass. But this also means children can lose fluids and electrolytes faster through sweating, theoretically making them more susceptible to dehydration.

    Meanwhile, younger children, particularly babies, can’t sweat as much as older children and adults. This means they can’t cool down as effectively.

    Children in general also tend to engage in more outdoor physical activity, which might see them more exposed to very hot temperatures.

    Further, children may be less in-tune to the signals their body is giving them that they’re overheating, such as excessive sweating or red skin. So they might not stop and cool down when they need to. Young children especially may not recognise the early signs of heat stress or be able to express discomfort.

    A boy drinking from a drink bottle, appears hot and bothered.
    Children may not easily be able to communicate that they’re hot and bothered. christinarosepix/Shutterstock

    Our study

    We wanted to examine children’s exposure to extreme heat stress and the associated risks to their health.

    We measured extreme heat as “heatwave days”, at least two consecutive days with a daily maximum temperature above the 95th percentile for the relevant area on a universal thermal climate index. This ranged from 27°C to 45°C depending on the area.

    We assessed health outcomes by looking at ED visits and unplanned hospital admissions among children aged 0–18 years from NSW between 2000 and 2020. This totalled around 8.2 million ED visits and 1.4 million hospital admissions.

    We found hospital admissions for heat-related illness were 104% more likely on heatwave days compared to non-heatwave days, and ED visits were 78% more likely. Heat-related illness includes a spectrum of disorders from minor conditions such as dehydration to life-threatening conditions such as heat stroke.

    But heat-related illness wasn’t the only condition that increased on heatwave days. There was also an increase in childhood infections, particularly infectious enteritis possibly related to food poisoning (up 6% for ED visits and 17% for hospital admissions), ear infections (up 30% for ED visits and 3% for hospital admissions), and skin and soft tissue infections (up 6% for ED visits and 4% for hospital admissions).

    A boy standing in front of a sprinkler.
    Kids can be more vulnerable in the heat because of their behaviour and physiology. K-FK/Shutterstock

    We know many infectious diseases are highly seasonal. Some, like the flu, peak in winter. But heat and humidity increase the risk of certain infections caused by bacterial, viral and fungal pathogens.

    For example, warmer weather and higher humidity can increase the survival of bacteria, such as Salmonella, on foods, which increases the risk of food poisoning.

    Hot weather can also increase the risk of ear infections. Children may be at greater risk during hot weather because they often swim or play at the beach or pool. Water can stay in the ear after swimming and a moist environment in the ear canal can cause growth of pathogens leading to ear infections.

    Which children are most vulnerable?

    During heatwaves, we found infants aged under one were at increased risk of ED visits and hospital admission for any reason compared to older children. This is not surprising, because babies can’t regulate their body temperature effectively and are reliant on their caregivers to keep them cool.

    Our study also found children from the most disadvantaged areas were more vulnerable to heat-related illness on heatwave days. Although we don’t know exactly why, we hypothesised families from poorer areas might have limited access to air-conditioning and could be more likely to live in hotter neighbourhoods.

    Keeping kids cool: tips for parents

    The highest levels of heat exposure on hot days for young children is usually when they’re taken outside in prams and strollers. To protect their children from direct sunlight, parents often instinctively cover their stroller with a cloth such as a muslin.

    However, a recent study from our group showed this actually increases temperatures inside a stroller to as much as 3–4˚C higher than outside.

    But if the cloth is wet with water, and a small fan is used to circulate the air close to the child, stroller temperatures can be 4–5˚C lower than outside. Wetting the cloth every 15–20 minutes (for example, with a spray bottle) maintains the cooling effect.

    When young children are not in a stroller, and for older children, there are a few things to consider to keep them cool and safe.

    Remember temperatures reported on weather forecasts are measured in the shade, and temperatures in the sun can be up to 15˚C higher. So sticking to the shade as much as possible is important.

    Exercise generates heat inside the body, so activities should be shortened, or rescheduled to cooler times of the day.

    Sunscreen and hats are important when outdoors, but neither are especially effective for keeping cool. Spraying water on the child’s skin – not just the face but arms, legs and even the torso if possible – can help. Wetting their hats is another idea.

    Proper hydration on hot days is also essential. Regular water breaks, including offering water before, during and after activity, is important. Offering foods with high water content such as watermelon and orange can help with hydration too.

    Wen-Qiang He, Research Fellow in Biostatistics and Epidemiology, Faculty of Medicine and Health, University of Sydney; James Smallcombe, Post-doctoral Research Associate, Faculty of Medicine and Health, University of Sydney; Natasha Nassar, Professor of Paediatric and Perinatal Epidemiology and Chair in Translational Childhood Medicine, University of Sydney, and Ollie Jay, Professor of Heat & Health; Director of Heat & Health Research Incubator; Director of Thermal Ergonomics Laboratory, University of Sydney

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Gluten intolerance and coeliac disease can both cause nausea, bloating and pain. What’s the difference?

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    Around one in ten Australians say they follow a gluten-free diet.

    This means eliminating common foods – such as bread, pasta and noodles – that contain gluten, a protein found mainly in wheat, barley and rye.

    Not everyone who follows a gluten-free diet has an underlying condition. But if you experience nausea, bloating or stomach pain after eating gluten, it could be the sign of a gluten intolerance, or coeliac disease.

    While gluten intolerance and coeliac disease share many similar symptoms, one can cause intestinal damage and malnutrition. So, what’s the difference?

    fotodrobik/Shutterstock

    What is coeliac disease?

    Coeliac disease is an autoimmune disease. This means the body mistakenly starts attacking healthy cells and tissue – in this case, in the small intestine – causing inflammation.

    It affects around one in 70 Australians, but only 20% of this group are diagnosed.

    If you have coeliac disease, eating foods that contain gluten can damage your villi, structures in the small intestine that help the body absorb nutrients.

    Following a meal containing gluten, you may experience digestive problems including diarrhoea, bloating, nausea, gas and abdominal pain.

    Diagram shows healthy villi in the small intestine versus villi damaged by coeliac disease.
    Coeliac disease can lead to long-term damage in the small intenstine. Sakurra/Shutterstock

    Gluten can also cause non-digestive symptoms such as brain fog, headaches, dermatitis herpetiformis (an itchy, blistery skin rash), joint pain and fatigue.

    In the long term, untreated coeliac disease can lead to malnutrition because the damaged villi can’t absorb nutrients from food. It can also reduce bone mineral density and has been linked to neurological disorders such as epilepsy and dementia.

    How is coeliac disease diagnosed?

    For an accurate diagnosis, you must not have eliminated gluten from your diet yet. This is so its effect on your digestive system can be measured.

    A diagnosis involves blood tests followed by biopsies of the small intestine using an endoscope (an instrument with a light that can look inside the body).

    Blood tests look for antigens – markers of a reaction to gluten – while the biopsy inspects any damage to the villi in the intestine.

    In some cases, a capsule endoscopy, where a pill-sized camera is swallowed, is used to look at the intestine and observe for damage.

    What about gluten intolerance?

    People with gluten intolerance experience similar symptoms to coeliac disease. The difference is, after consuming gluten, there is no autoimmune response or intestinal damage.

    Gluten intolerance is sometimes known as non-coeliac gluten sensitivity.

    An estimated 1% of Australians live with a gluten intolerance, but only 12 in every 100 of this group are diagnosed by a doctor.

    Doctors will rule out coeliac disease and wheat allergies as a first step for a person with symptoms related to eating gluten.

    Once these have been ruled out, a gluten-free diet trial, supervised by an accredited practising dietitian, might be recommended to see if symptoms improve.

    A formal diagnosis of gluten intolerance can only be confirmed using a highly complex dietary trial that compares the effect of gluten and a placebo over at least eight weeks.

    This form of scientific study is very labour-intensive and not very common.

    So instead many people just choose to eliminate gluten, without a diagnosis.

    Extreme sensitivity to gluten

    Coeliac disease is more severe than gluten intolerance and sensitivity can vary among those diagnosed.

    Even traces of gluten can trigger symptoms. This means a strict, lifelong, gluten-free diet essential.

    It also means people with coeliac disease have to be careful about cross-contamination. For example, using the same knife, chopping board or toaster to cut or toast gluten-free bread and regular bread can transfer gluten particles and cause a reaction.

    According to the latest studies, consuming just 50mg of gluten per day is enough to cause intestinal damage for people with coeliac disease.

    For context, a slice of whole-wheat bread contains about 4,800mg of gluten, meaning 50mg is around 1/100th of a slice of bread.

    A small amount of gluten won’t affect someone with gluten intolerance in the same way. They may have temporary symptoms, but won’t experience intestinal damage.

    However, the symptoms and their severity can vary from person to person, depending on their individual sensitivity.

    Should I cut out gluten, just in case?

    You might be wondering if there is a downside to avoiding gluten, if you don’t have coeliac disease or an intolerance.

    There can be.

    Grain foods that contain gluten are rich in essential nutrients such as fibre, folate, iron and B-group vitamins.

    Avoiding gluten when you don’t need to can lead to nutritional deficiencies.

    Gluten-free products can also be more expensive and are sometimes higher in sugar, salt and fat to help compensate for texture and taste.

    Before making any changes to your diet, it is best to speak with an accredited practising dietitian to make sure you’re not missing out on important nutrients.

    So, what if you have symptoms?

    Common signs of a gluten intolerance or coeliac disease include bloating, diarrhoea or constipation, and stomach pain. Both conditions can trigger non-gastrointestinal symptoms such as headaches, fatigue and joint pain.

    If these symptoms sound familiar, it’s best to speak to a health-care professional who may test you for coeliac disease and/or a wheat allergy before eliminating gluten from your diet.

    Remember, self-diagnosing and removing gluten without proper guidance might do you more harm than good.

    If your symptoms concern you, speak to your GP, a gastroenterologist or a qualified dietitian. Dietitians Australia has a list of accredited practising dietitians.

    Yasmine Probst, Professor, School of Medical, Indigenous and Health Sciences. Advanced Accredited Practising Dietitian, University of Wollongong and Olivia Wills, Associate Lecturer, Nutrition and Dietetics, University of Wollongong

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • How Much Does A Vegan Diet Affect Biological Aging?

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    Slow Your Aging, One Meal At A Time

    This one’s a straightforward one today, and the ““life hack” can be summed up:

    Enjoy a vegan diet to enjoy younger biological age.

    First, what is biological age?

    Biological age is not one number, but a collection of numbers, as per different biomarkers of aging, including:

    • Visual markers of aging (e.g. wrinkles, graying hair)
    • Performative markers of aging (e.g. mobility tests)
    • Internal functional markers of aging (e.g. tests for cognitive decline, eyesight, hearing, etc)
    • Cellular markers of aging (e.g. telomere length)

    We wrote more about this here:

    Age & Aging: What Can (And Can’t) We Do About It?

    A vegan diet may well impact multiple of those categories of aging, but today we’re highlighting a study (hot off the press; published only a few days ago!) that looks at its effect on that last category: cellular markers of aging.

    There’s an interesting paradox here, because this category is:

    • the most easily ignorable; because we all feel it if our knees are giving out or our skin is losing elasticity, but who notices if telomeres’ T/S ratio changed by 0.0407? ← the researchers, that’s who, as this difference is very significant
    • the most far-reaching in its impact, because cellular aging in turn has an effect on all the other markers of aging

    Second, how much difference does it make, and how do we know?

    The study was an eight-week interventional identical twin study. This means several things, to start with:

    • Eight weeks is a rather short period of time to accumulate cellular aging, let alone for an intervention to accumulate a significant difference in cellular aging—but it did. So, just imagine what difference it might make in a year or ten!
    • Doing an interventional study with identical twin pairs already controlled for a lot of factors, that are usually confounding variables in population / cohort / longitudinal / observational studies.

    Factors that weren’t controlled for by default by using identical twins, were controlled for in the experiment design. For example, twin pairs were rejected if one or more twin in a given pair already had medical conditions that could affect the outcome:

    ❝Inclusion criteria involved participants aged ≥18, part of a willing twin pair, with BMI <40, and LDL-C <190 mg/dL. Exclusions included uncontrolled hypertension, metabolic disease, diabetes, cancer, heart/renal/liver disease, pregnancy, lactation, and medication use affecting body weight or energy.

    Eligibility was determined via online screening, followed by an orientation meeting and in-person clinic visit. Randomization occurred only after completing baseline visits, dietary recalls, and questionnaires for both twins❞

    ~ Dr. Varun Dwaraka et al. ← there’s a lot of “et al.” to this one; the paper had 16 collaborating authors!

    As to the difference it made over the course of the 8 weeks…

    ❝Various measures of epigenetic age acceleration (PC GrimAge, PC PhenoAge, DunedinPACE) were assessed, along with system-specific effects (Inflammation, Heart, Hormone, Liver, and Metabolic).

    Distinct responses were observed, with the vegan cohort exhibiting significant decreases in overall epigenetic age acceleration, aligning with anti-aging effects of plant-based diets. Diet-specific shifts were noted in the analysis of methylation surrogates, demonstrating the influence of diet on complex trait prediction through DNA methylation markers.❞

    ~ Ibid.

    You can read the whole paper here (it goes into a lot more detail than we have room to here, and also gives infographics, charts, numbers, the works):

    Unveiling the epigenetic impact of vegan vs. omnivorous diets on aging: insights from the Twins Nutrition Study (TwiNS)

    Were they just eating more healthily, though?

    Well, arguably yes, as the results show, but to be clear:

    The omnivorous diet compared to the vegan diet in this study was also controlled; both groups were given a healthy meal plan for their respective diet. So this wasn’t a case of “any omnivorous diet vs healthy vegan diet”, but rather “healthy omnivorous diet vs healthy vegan diet”.

    Again, the paper itself has the full details—a short version is that it involved a healthy meal kit delivery service, followed by ongoing dietician involvement in an equal and carefully-controlled fashion.

    So, aside from that one group had an omnivorous meal plan and the other vegan, both groups received the same level of “healthy eating” support, guidance, and oversight.

    But isn’t [insert your preferred animal product here] healthy?

    Quite possibly! For general health, general scientific consensus is that eating at least mostly plants is best, red meat is bad, poultry is neutral in moderation, fish is good in moderation, dairy is good in moderation if fermented, eggs are good in moderation if not fried.

    This study looked at the various biomarkers of aging that we listed, and not every possible aspect of health—there’s more science yet to be done, and the researchers themselves are calling for it.

    It also bears mentioning that for some (relatively few, but not insignificantly few) people, extant health conditions may make a vegan diet unhealthy or otherwise untenable. Do speak with your own doctor and/or dietician if unsure.

    See also: Do We Need Animal Products To Be Healthy?

    We would hypothesize, by the way, that the anti-aging benefits of a vegan diet are probably proportional to abstention from animal products—meaning that even if you simply have some “vegan days”, while still consuming animal products other days, you’ll still get benefit for the days you abstained. That’s just our hypothesis though.

    Take care!

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