Optimal Black Pepper Dosage and Supplement

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It’s Q&A Day at 10almonds!

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In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

So, no question/request too big or small

❝I may have missed it, but how much black pepper provides benefits?❞

So, for any new subscribers joining us today, this is about two recent main features:

As for a daily dosage of black pepper, it varies depending on the benefit you’re looking for, but:

  • 5–20mg of piperine is the dosage range used in most scientific studies we looked at
  • 10mg is a very common dosage found in many popular supplements
  • That’s the mass of piperine though, so if taking it as actual black pepper rather than as an extract, ½ teaspoon is considered sufficient to enjoy benefits.

❝I loved the health benefits of pepper. I do not like pepper. Where can I get it as a supplement?❞

You can simply buy whole black peppercorns and take a few with water as though they were tablets. Your stomach acid will do the rest. Black pepper is also good for digestion, so taking it with a meal is best.

You can buy piperine (black pepper extract) by itself as a supplement in powder form, but if you don’t like black pepper, you will probably not like this powder either. We couldn’t find it readily in capsule form.

You can buy piperine (black pepper extract) as an adjunct to other supplements, with perhaps the most common/popular being turmeric capsules that also contain 10mg (or more) piperine per capsule. Shop around if you like, but here’s one that has 15mg piperine* per capsule, for example.

*They call it “Bioperine®” but that is literally just piperine. Same go

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  • Red-dy For Anything Polyphenol Salad

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    So, you’ve enjoyed your Supergreen Superfood Salad Slaw, and now you’re ready for another slice of the rainbow. Pigments in food aren’t just for decoration—they each contain unique benefits! Today’s focus is on some red foods that, combined, make a deliciously refreshing salad that’s great for the gut, heart, and brain.

    You will need

    • 1 cup crème fraîche or sour cream (if vegan, use our Plant-Based Healthy Cream Cheese recipe, and add the juice of 1 lime)
    • ½ small red cabbage, thinly sliced
    • 1 red apple, cored and finely chopped
    • 1 red onion, thinly sliced
    • 10 oz red seedless grapes, halved
    • 10 oz red pomegranate seeds
    • 1 tsp red chili flakes

    Method

    (we suggest you read everything at least once before doing anything)

    1) Combine all the red ingredients in a big bowl.

    2) Add the crème fraîche and mix gently but thoroughly.

    3) If you have time, let it sit in the fridge for 48 hours before enjoying, as its colors will intensify and its polyphenols will become more bioavailable. But if you want/need, you can serve immediately; that’s fine too.

    Enjoy!

    Want to learn more?

    For those interested in some of the science of what we have going on today:

    Take care!

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  • An Underrated Tool Against Alzheimer’s

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Dementia in general, and Alzheimer’s in particular, affects a lot of people, and probably even more than the stats show, because some (estimated to be: about half) will go undiagnosed and thus unreported:

    Alzheimer’s: The Bad News And The Good

    At 10almonds, we often talk about brain health, whether from a nutrition standpoint or other lifestyle factors. For nutrition, by the way, check out:

    Brain Food? The Eyes Have It!

    Today we’ll be looking at some new science for an underrated tool:

    Bilingualism as protective factor

    It’s well-known that bilingualism offers brain benefits, but most people would be hard-pressed to name what, specifically, those brain benefits are.

    As doctors Kristina Coulter and Natalie Phillips found in a recent study, one of the measurable benefits may be a defense against generalized (i.e. not necessarily language-related) memory loss Alzheimer’s disease.

    Specifically,

    ❝We used surface-based morphometry methods to measure cortical thickness and volume of language-related and AD-related brain regions. We did not observe evidence of brain reserve in language-related regions.

    However, reduced hippocampal volume was observed for monolingual, but not bilingual, older adults with AD. Thus, bilingualism is hypothesized to contribute to reserve in the form of brain maintenance in the context of AD.❞

    Read in full: Bilinguals show evidence of brain maintenance in Alzheimer’s disease

    This is important, because while language is processed in various parts of the brain beyond the scope of this article, the hippocampi* are where memory is stored.

    *usually mentioned in the singular as “hippocampus”, but you have one on each side, unless some terrible accident or incident befell you.

    What this means in practical terms: these results suggest that being bilingual means we will retain more of our capacity for memory, even if we get Alzheimer’s disease, than people who are monolingual.

    Furthermore, while we’re talking practicality:

    ❝…our subsample may be characterized as mostly late bilinguals (i.e., learning an L2 after age 5), having moderate self-reported L2 ability, and relatively few participants reporting daily L2 use (33 out of 119)❞

    (L2 = second language)

    This is important, because it means you don’t have to have grown up speaking multiple languages, you don’t even have to speak it well, and you don’t have to be using your second language(s) on a daily basis, to enjoy benefits. Merely having them in your head appears to be sufficient to trigger the brain to go “oh, we need to boost and maintain the hippocampal volume”.

    We would hypothesize that using second language(s) regularly and/or speaking second language(s) well offers additional protection, and the data would support this if it weren’t for the fact that the sample sizes for daily and high-level speakers are a bit small to draw conclusions.

    But the important part is: simply knowing another language, including if you literally just learned it later in life, is already protective of hippocampal volume in the context of Alzheimer’s disease.

    Here’s a pop-science article about the study, that goes into it in more detail than we have room to here:

    Bilingualism linked to greater brain resilience in older adults

    Want to learn a new language?

    Here are some options where you can get going right away:

    Duolingo | Babbel | Lernu

    If you are thinking “sounds good, but learning a language is too much work”, then that is why we included that third option there. It’s specifically for one language, and that language is Esperanto, arguably the world’s easiest language and specifically designed to be super quick and easy to get good at. Also, it’s free!

    Do, kial ne lerni novan lingvon rapide kaj facile? 😉

    Want to know more?

    For ways to reduce your overall Alzheimer’s risk according to science, check out:

    Reduce Your Alzheimer’s Risk

    Take care!

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  • Taurine’s Benefits For Heart Health And More

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    Taurine: Research Review

    First, what is taurine, beyond being an ingredient in many energy drinks?

    It’s an amino acid that many animals, including humans, can synthesize in our bodies. Some other animals—including obligate carnivores such as cats (but not dogs, who are omnivorous by nature) cannot synthesize taurine and must get it from food.

    So, as humans are very versatile omnivorous frugivores by nature, we have choices:

    • Synthesize it—no need for any conscious action; it’ll just happen
    • Eat it—by eating meat, which contains taurine
    • Supplement it—by taking supplements, including energy drinks, which generally (but not always) use a bioidentical lab-made taurine. Basically, lab-made taurine is chemically identical to the kind found in meat, it’s just cheaper and doesn’t involve animals as a middleman.

    What does it do?

    Taurine does a bunch of essential things, including:

    • Maintaining hydration/electrolyte balance in cells
    • Regulating calcium/magnesium balance in cells
    • Forming bile salts, which are needed for digestion
    • Supporting the integrity of the central nervous system
    • Regulating the immune system and antioxidative processes

    Thus, a shortage of taurine can lead to such issues as kidney problems, eye tissue damage (since the eyes are a particularly delicate part of the CNS), and cardiomyopathy.

    If you want to read more, here’s an academic literature review:

    Taurine: A “very essential” amino acid

    On the topic of eye health, a 2014 study found that taurine is the most plentiful amino acid in the eye, and helps protect against retinal degeneration, in which they say:

    ❝We here review the evidence for a role of taurine in retinal ganglion cell survival and studies suggesting that this compound may be involved in the pathophysiology of glaucoma or diabetic retinopathy. Along with other antioxidant molecules, taurine should therefore be seriously reconsidered as a potential treatment for such retinal diseases❞

    Read more: Taurine: the comeback of a neutraceutical in the prevention of retinal degenerations

    Taurine for muscles… In more than sports!

    We’d be remiss not to mention that taurine is enjoyed by athletes to enhance athletic performance; indeed, it’s one of its main selling-points:

    See: Taurine in sports and exercise

    But! It’s also useful for simply maintaining skeleto-muscular health in general, and especially in the context of age-related decline and chronic disease:

    Taurine: the appeal of a safe amino acid for skeletal muscle disorders

    On the topic of safety… How safe is it?

    There’s an interesting answer to that question. Within safe dose ranges (we’ll get to that), taurine is not only relatively safe, but also, studies that looked to explore its risks found new benefits in the process. Specifically of interest to us were that it appears to promote better long-term memory, especially as we get older (as taurine levels in the brain decline with age):

    Taurine, Caffeine, and Energy Drinks: Reviewing the Risks to the Adolescent Brain

    ^Notwithstanding the title, we assure you, the research got there; they said:

    ❝Interestingly, the levels of taurine in the brain decreased significantly with age, which led to numerous studies investigating the potential neuroprotective effects of supplemental taurine in several different experimental models❞

    What experimental models were those? These ones:

    …which were all animal studies, however.

    The same systematic review also noted that not only was more research needed on humans, but also, existing studies have had a strong bias to male physiology (in both human and assorted other animal studies), so more diverse study is needed too.

    What are the safe dose ranges?

    Before we get to toxicity, let’s look at some therapeutic doses. In particular, some studies that found that 500mg 3x daily, i.e. 1.5g total daily, had benefits for heart health:

    Bottom line on safety: 3g/day has been found to be safe:

    Click here to see the findings of the risk assessment published in the Journal of Regulatory Toxicology and Pharmacology

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    Dr. Herman Pontzer presents a very useful overview of not just what our metabolism is and how it works, but also why.

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  • How To En-Joy Life (With Long-Term Benefits)

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    New Year’s Dissolutions?

    We have talked previously about:

    The Science Of New Year’s Pre-Resolutions

    …and here we are now at the end of the first week of January; how’s it going?

    Hopefully, based on that article, it’s been going just great since December! For most people, statistically speaking, it hasn’t.

    Around now is typically when many people enter the “bargaining” stage of New Year’s Resolutions, which at this point are often in serious danger of becoming New Year’s Dissolutions.

    What’s important, really?

    When trying to juggle potentially too many new items, it’s important to be able to decide where to focus one’s efforts in the case of needing to drop a ball or two.

    First, the laziest way…

    The path of least resistance

    This is perhaps most people’s go-to. It, without too much thought, drops whatever feels most onerous, and continues with what seems easiest.

    This is not a terrible approach, because what we enjoy, we will be more likely to continue. But it can be improved upon, while still getting that benefit.

    Marie Kondo your resolutions values

    Instead of throwing out the new habits that “don’t spark joy”, ask yourself:

    “What brings me joy?”

    …because often, the answer is something that’s a result of a thing that didn’t “spark joy” directly. Many things in life involve delayed gratification.

    Let’s separate the [unwanted action] from the [wanted result] for a moment.

    Rather than struggling on with something unpleasant for the hope of joy at the end of the rainbow, though, give yourself permission to improve the middle bit.

    For example, if the idea of having lots of energy and good cardiovascular fitness is what prompted you to commit to those 6am runs each morning (but they’re not actually joyous in your experience), what would be more fun and still give you the same benefit?

    Now that you know “having lots of energy and good CV fitness” is what sparks joy, not “getting up to run at 6am”, you can change lanes without pulling off the highway entirely.

    Maybe a dance class will be more your speed, for example.

    The key here is: you’ll have changed your resolution, without breaking it in any way that mattered

    Want more ways to keep on track without burning out?

    Who doesn’t? So, check out:

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    Enjoy!

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  • The Dopamine Myth

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    The Dopamine Myth

    There’s a popular misconception that, since dopamine is heavily involved in addictions, it’s the cause.

    We see this most often in the context of non-chemical addictions, such as:

    • gambling
    • videogames
    • social media

    And yes, those things will promote dopamine production, and yes, that will feel good. But dopamine isn’t the problem.

    Myth: The Dopamine Detox

    There’s a trend we’ve mentioned before (it got a video segment a few Fridays back) about the idea of a “dopamine detox“, and how unscientific the idea is.

    For a start…

    • You cannot detox from dopamine, because dopamine is not a toxin
    • You cannot abstain from dopamine, because your brain regulates your dopamine levels to keep them correct*
    • If you could abstain from dopamine (and did), you would die, horribly.

    *unless you have a serious mental illness, for example:

    • forms of schizophrenia and/or psychosis that involve too much dopamine, or
    • forms of depression and/or neurodegenerative diseases such as Parkinson’s (and several kinds of dementia) in which you have too little dopamine
    • bipolar disorder in which dopamine levels can swing too far each way

    See also: Dopamine fasting: misunderstanding science spawns a maladaptive fad

    Myth: Dopamine is all about pleasure

    Dopamine is a pleasure-giving neurotransmitter, but it serves more purposes than that! It also plays a central role in many neurological processes, including:

    • Motivation
    • Learning and memory
    • Motor functions
    • Language faculties
    • Linear task processing

    Note for example how someone taking dopaminergic drugs (prescription or otherwise; could be anything from modafinil to cocaine) is not blissed out… They’re probably in a good mood, sure, but they’re focused, organized, quick-thinking, and so forth! This is not an ad for cocaine; cocaine is very bad for the health. But you see the features? So, what if we could have a little more dopamine… healthily?

    Dopamine—à la carte

    Let’s look at the examples we gave earlier of non-chemical addictions that are dopaminergic in nature:

    • gambling
    • videogames
    • social media

    They’re not actually that rewarding, are they?

    • Gamblers lose more than they win
    • Gamers cease to care about a game once they have won
    • Social media more often results in “doomscrolling”

    This is because what prompts the most dopamine is actually the anticipation of reward… not the thing itself, whose reward-pleasure is very fleeting. Nobody looks back at an hour of doomscrolling and thinks “well, that was fun; I’m glad I did that”.

    See the science: Liking, Wanting and the Incentive-Sensitization Theory of Addiction

    But what if we anticipated a reward from things that are not deleterious to health and productivity? Things that are neutral, or even good for us?

    Examples of this include:

    • Sex! (remember though, it’s not a race to the finish-line)
    • Good, nourishing food (bonus: some foods boost dopamine production nutritionally)
    • Exercise/sport (also prompts release of endorphins, win/win!)
    • Gamified learning apps (e.g. Duolingo)
    • Gamified health/productivity apps (anything with bells and whistles and things that go “ding” and measure streaks etc)

    Want to know more?

    That’s all we have time for today, but you might want to check out:

    10 Best Ways to Increase Dopamine Levels Naturally ← Science-based and well-sourced article!

    Don’t Forget…

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