Milk Thistle For The Brain, Bones, & More

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“Thistle Do Nicely”

Milk thistle is a popular supplement; it comes from the milk thistle plant (Silybum marianum), commonly just called thistles. There are other kinds of thistle too, but these are one of the most common.

So, what does it do?

Liver health

Milk thistle enjoys popular use to support liver health; the liver is a remarkably self-regenerative organ if given the chance, but sometimes it can use a helping hand.

See for example: How To Undo Liver Damage

As for milk thistle’s beneficence, it is very well established:

Brain health

For this one the science is less well-established, as studies so far have been on non-human animals, or have been in vitro studies.

Nevertheless, the results so far are promising, and the mechanism of action seems to be a combination of reducing oxidative stress and neuroinflammation, as well as suppressing amyloid β-protein (Aβ) fibril formation, in other words, reducing amyloid plaques.

General overview: A Mini Review on the Chemistry and Neuroprotective Effects of Silymarin

All about the plaques, but these are non-human animal studies:

Against diabetes

Milk thistle improves insulin sensitivity, and reduces fasting blood sugar levels and HbA1c levels. The research so far is mostly in type 2 diabetes, however (at least, so far as we could find). For example:

Silymarin in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Studies we could find for T1D were very far from translatable to human usefulness, for example, “we poisoned these rats with streptozotocin then gave them megadoses of silymarin (10–15 times the dose usually recommended for humans) and found very small benefits to the lenses of their eyes” (source).

Against osteoporosis

In this case, milk thistle’s estrogenic effects may be of merit to those at risk of menopause-induced osteoporosis:

Antiosteoclastic activity of milk thistle extract after ovariectomy to suppress estrogen deficiency-induced osteoporosis

If you’d like a quick primer about such things as what antiosteoclastic activity is, here’s a quick recap:

Which Osteoporosis Medication, If Any, Is Right For You?

Is it safe?

It is “Generally Recognized As Safe”, and even when taken at high doses for long periods, side effects are very rare.

Contraindications include if you’re pregnant, nursing, or allergic.

Potential reasons for caution (but not necessarily contraindication) include if you’re diabetic (its blood-sugar lowering effects will decrease the risk of hyperglycemia while increasing the risk of hypoglycemia), or have a condition that could be exacerbated by its estrogenic effects—including if you are on HRT, because it’s an estrogen receptor agonist in some ways (for example those bone benefits we mentioned before) but an estrogen antagonist in others (for example, in the uterus, if you have one, or in nearby flat muscles, if you don’t).

As ever, speak with your doctor/pharmacist to be sure.

Want to try it?

We don’t sell it, but here for your convenience is an example product on Amazon

Enjoy!

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  • Age & Aging: What Can (And Can’t) We Do About It?

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    How old do you want to be?

    We asked you how old you are, and got an interesting spread of answers. This wasn’t too surprising; of course we have a general idea of who our readership is and we write accordingly.

    What’s interesting is the gap for “40s”.

    And, this wasn’t the case of a broken poll button, it’s something that crops up a lot in health-related sociological research. People who are most interested in taking extra care of their body are often:

    • Younger people full of optimism about maintaining this perfectly healthy body forever
    • Older people realizing “if I don’t want to suffer avoidable parts of age-related decline, now is the time to address these things”

    In between, we often have a gap whereby people no longer have the optimism of youth, but do not yet feel the pressure of older age.

    Which is not to say there aren’t 40-somethings who do care! Indeed, we know for a fact we have some subscribers in their 40s (and some in their 90s, too), just, they evidently didn’t vote in this poll.

    Anyway, let’s bust some myths…

    Aging is inevitable: True or False?

    False, probably. That seems like a bold (and fortune-telling) claim, so let’s flip it to deconstruct it more logically:

    Aging is, and always will be, unstoppable: True or False?

    That has to be “False, probably”. To say “true” now sounds like an even bolder claim. Just like “the moon will always be out of reach”.

    • When CPR was first developed, first-aiders were arrested for “interfering with a corpse”.
    • Many diseases used to be death sentences that are now “take one of these in the morning”
      • If you think this is an appeal to distant history, HIV+ status was a death sentence in the 90s. Now it’s “take one of these in the morning”.

    But, this is an appeal to the past, and that’s not always a guarantee of the future. Where does the science stand currently? How is the research and development doing on slowing, halting, reversing aging?

    We can slow aging: True or False?

    True! There’s a difference between chronological age (i.e., how much time has passed while we’ve been alive) and biological age (i.e., what our diverse markers of aging look like).

    Biological age often gets talked about as a simplified number, but it’s more complex than that, as we can age in different ways at different rates, for example:

    • Visual markers of aging (e.g. wrinkles, graying hair)
    • Performative markers of aging (e.g. mobility tests)
    • Internal functional markers of aging (e.g. tests for cognitive decline, eyesight, hearing, etc)
    • Cellular markers or aging (e.g. telomere length)
    • …and more, but we only have so much room here

    There are things we can do to slow most of those, including:

    In the case of cognitive decline particularly, check out our previous article:

    How To Reduce Your Alzheimer’s Risk

    It’s too early to worry about… / It’s too late to do anything about… True or False?

    False and False!

    Many things that affect our health later in life are based on early-life choices and events. So it’s important for young people to take advantage of that. The earlier one adopts a healthy lifestyle, the better, because, and hold onto your hats for the shocker here: aging is cumulative.

    However, that doesn’t mean that taking up healthy practices (or dropping unhealthy ones) is pointless later in life, even in one’s 70s and beyond!

    Read about this and more from the National Institute of Aging:

    What Do We Know About Healthy Aging?

    We can halt aging: True or False?

    False, for now at least. Our bodies are not statues; they are living organisms, constantly rebuilding themselves, constantly changing, every second of every day, for better or for worse. Every healthy or unhealthy choice you make, every beneficial or adverse experience you encounter, affects your body on a cellular level.

    Your body never, ever, stops changing for as long as you live.

    But…

    We can reverse aging: True or False?

    True! Contingently and with limitations, for now at least.

    Remember what we said about your body constantly rebuilding itself? That goes for making itself better as well as making itself worse.

    But those aren’t really being younger, we’ll still die when our time is up: True or False?

    False and True, respectively.

    Those kinds of things are really being younger, biologically. What else do you think being biologically younger is?

    We may indeed die when our time is up, but (unless we suffer fatal accident or incident first) “when our time is up” is something that is decided mostly by the above factors.

    Genetics—the closest thing we have to biological “fate”—accounts for only about 25% of our longevity-related health*.

    Genes predispose, but they don’t predetermine.

    *Read more: Human longevity: Genetics or Lifestyle? It takes two to tango

    (from the Journal of Immunity and Ageing)

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  • Make Overnight Oats Shorter Or Longer For Different Benefits!

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    It’s Q&A Day at 10almonds!

    Have a question or a request? We love to hear from you!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    ❝How long do I have to soak oats for to get the benefits of “overnight oats”?❞

    The primary benefit of overnight oats (over cooked oats) is that they are soft enough to eat without having been cooked (as cooking increases their glycemic index).

    So, if it’s soft, it’s good to eat. A few hours should be sufficient.

    Bonus information

    If, by the way, you happen to leave oats and milk (be it animal or plant milk) sealed in a jar at room temperature for a 2–3 days (less if your “room temperature” is warmer than average), it will start to ferment.

    • Good news: fermentation can bring extra health benefits!
    • Bad news: you’re on your own if something pathogenic is present

    For more on this, you might like to read:

    Fermenting Everything: How to Make Your Own Cultured Butter, Fermented Fish, Perfect Kimchi, and Beyond

    Enjoy!

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  • Dr. Kim Foster’s Method For Balancing Hormones Naturally

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    Not just sex hormones, but also hormones like cortisol (the stress hormone), and thyroid hormones (for metabolism regulation) too! The body is most of the time self-regulating when it comes to hormones, but there are things that we can do to help our body look after us correctly.

    In short, if we give our body what it needs, it will (usually, barring serious illness!) give us what we need.

    Dr. Foster recommends…

    Foods:

    • Healthy fats (especially avocados and nuts)
    • Lean proteins (especially poultry, fish, and legumes)
    • Fruits & vegetables (especially colorful ones)
    • Probiotics (especially fermented foods like sauerkraut, kimchi, etc)
    • Magnesium-rich foods (especially dark leafy greens, nuts, and yes, dark chocolate)

    Teas:

    • Camomile tea (especially beneficial against cortisol overproduction)
    • Nettle tea (especially beneficial for estrogen production)
    • Peppermint tea (especially beneficial for gut health, thus indirect hormone benefits)

    Stress reduction:

    • Breathing exercises (especially mindfulness exercises)
    • Yoga (especially combining exercise with stretches)
    • Spending time in nature (especially green spaces)

    Dr. Foster explains more about all of these things, along with more illustrative examples, so if you can, do enjoy her video:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to read more about this topic?

    You might like our main feature: What Does “Balance Your Hormones” Even Mean?

    Enjoy!

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    Is it OK if my child eats lots of fruit but no vegetables?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Does it seem like most vegetables you serve your children end up left on the plate, or worse, strewn across the floor? But mention dessert, and your fruit skewers are polished off in an instant.

    Or maybe the carrot and cucumber sticks keep coming home in your child’s lunchbox untouched, yet the orange slices are nowhere to be seen.

    If you’re facing these struggles with your child, you’re not alone. Many children prefer fruit to vegetables.

    So if your child eats lots of fruit but minimal or no vegetables, is that OK? And how can you get them to eat more veggies?

    Children have an innate preference for fruit

    The Australian Dietary Guidelines’ recommended daily intakes for vegetables and fruit depend on a child’s age.

    A chart showing the serving amounts of fruit and veg for ages 4-18.
    Fruit and vegetable serving sizes by age. The Conversation.
    National Health and Medical Research Council, CC BY-SA

    Consumption among Australian children falls well below recommendations. Around 62.6% of children aged over two meet the recommended daily fruit intake, but only 9% meet the recommended vegetable intake.

    This is not surprising given children have a natural preference for fruit. At least in part, this is due to its sweetness and texture, whether crispy, crunchy or juicy. The texture of fruit has been linked to a positive sensory experience among children.

    Vegetables, on the other hand, are more of an acquired taste, and certain types, such as cruciferous vegetables, can be perceived by children as bitter.

    The reason children often prefer fruit over vegetables could also be related to the parents’ preferences. Some research has even suggested we develop food preferences before birth based on what our mother consumes during pregnancy.

    Balance is key

    So, a preference for fruit is common. But is it OK if your child eats lots of fruit but little to no vegetables? This is a question we, as dietitians, get asked regularly.

    You might be thinking, at least my child is eating fruit. They could be eating no veggies and no fruit. This is true. But while it’s great your child loves fruit, vegetables are just as important as part of a balanced eating pattern.

    Vegetables provide us with energy, essential vitamins and minerals, as well as water and fibre, which help keep our bowels regular. They also support a strong immune system.

    If your child is only eating fruit, they are missing some essential nutrients. But the same is true if they are eating only veggies.

    Fruit likewise provides the body with a variety of essential vitamins and minerals, as well as phytochemicals, which can help reduce inflammation.

    Evidence shows healthy consumption of fruit and vegetables protects against chronic diseases including high blood pressure, heart disease and stroke.

    Consumed together, fruit and vegetables in a variety of colours provide different nutrients we need, some of which we can’t get from other foods. We should encourage kids to eat a “rainbow” of fruit and vegetables each day to support their growth and development.

    What if my child eats too much fruit?

    If your child is eating slightly more fruit than what’s recommended each day, it’s not usually a problem.

    Fruit contains natural sugar which is good for you. But too much of a good thing, even if it’s natural, can create problems. Fruit also contains virtually no fat and very little to no protein, both essential for a growing child.

    When overindulging in fruit starts to displace other food groups such as vegetables, dairy products and meat, that’s when things can get tricky.

    6 tips to get your kids to love vegetables

    1. Get them involved

    Take your child with you when you go shopping. Let them choose new vegetables. See if you can find vegetables even you haven’t tried, so you’re both having a new experience. Then ask them to help you with preparing or cooking the vegetables using a recipe you have chosen together. This will expose your child to veggies in a positive way and encourage them to eat more.

    2. Sensory learning

    Try to expose your child to vegetables rather than hiding them. Kids are more likely to eat veggies when they see, smell and feel them. This is called sensory learning.

    3. Have fun with food

    Use colourful vegetables of different sizes and textures. Make them fun by creating scenes or faces on your child’s plate. Add edible flowers or mint for decoration. You can even serve this with a side of veggie-based dip such as hummus or guacamole for some bonus healthy fats.

    4. Teach them to grow their own

    Teach your child how to grow their own vegetables. Evidence shows kids are more inclined to try the food they have helped and watched grow. You don’t need to have a big backyard to do this. A windowsill with a pot plant is a perfect start.

    5. Lead by example

    Your child learns from you, and your eating habits will influence theirs. Ensure they see you eating and enjoying veggies, whether in meals or as snacks.

    6. Practise persistence

    If your child refuses a particular vegetable once, don’t give up. It can take many attempts to encourage children to try a new food.The Conversation

    Yasmine Probst, Associate Professor, School of Medical, Indigenous and Health Sciences, University of Wollongong; Olivia Wills, Accredited Practising Dietitian, PhD candidate, University of Wollongong, and Shoroog Allogmanny, Accredited Practising Dietitian, PhD candidate, University of Wollongong

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • The Compass of Pleasure – by Dr. David Linden

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    There are a lot of books about addiction, so what sets this one apart?

    Mostly, it’s that this one maintains that addiction is neither good nor bad per se—just, some behaviors and circumstances are. Behaviors and circumstances caused, directly or indirectly, by addiction.

    But, Dr. Linden argues, not every addiction has to be so. Especially behavioral addictions; the rush of dopamine one gets from a good session at the gym or learning a new language, that’s not a bad thing, even if they can fundamentally be addictions too.

    Similarly, we wouldn’t be here as a species without some things that rely on some of the same biochemistry as addictions; orgasms and eating food, for example. Yet, those very same urges can also inconvenience us, and in the case of foods and other substances, can harm our health.

    In this book, the case is made for shifting our addictive tendencies to healthier addictions, and enough information is given to help us do so.

    Bottom line: if you’d like to understand what is going on when you get waylaid by some temptation, and how to be tempted to better things, this book can give the understanding to do just that.

    Click here to check out The Compass of Pleasure, and make yours work in your favor!

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  • I’ve been sick. When can I start exercising again?

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    You’ve had a cold or the flu and your symptoms have begun to subside. Your nose has stopped dripping, your cough is clearing and your head and muscles no longer ache.

    You’re ready to get off the couch. But is it too early to go for a run? Here’s what to consider when getting back to exercising after illness.

    Ketut Subiyanto/Pexels

    Exercise can boost your immune system – but not always

    Exercise reduces the chance of getting respiratory infections by increasing your immune function and the ability to fight off viruses.

    However, an acute bout of endurance exercise may temporarily increase your susceptibility to upper respiratory infections, such as colds and the flu, via the short-term suppression of your immune system. This is known as the “open window” theory.

    A study from 2010 examined changes in trained cyclists’ immune systems up to eight hours after two-hour high-intensity cycling. It found important immune functions were suppressed, resulting in an increased rate of upper respiratory infections after the intense endurance exercise.

    So, we have to be more careful after performing harder exercises than normal.

    Can you exercise when you’re sick?

    This depends on the severity of your symptoms and the intensity of exercise.

    Mild to moderate exercise (reducing the intensity and length of workout) may be OK if your symptoms are a runny nose, nasal congestion, sneezing and minor sore throat, without a fever.

    Exercise may help you feel better by opening your nasal passages and temporarily relieving nasal congestion.

    Man walks on a beach
    If you have a runny or blocked nose and no fever, low-intensity movement such as a walk might help. Laker/Pexels

    However, if you try to exercise at your normal intensity when you are sick, you risk injury or more serious illness. So it’s important to listen to your body.

    If your symptoms include chest congestion, a cough, upset stomach, fever, fatigue or widespread muscle aches, avoid exercising. Exercising when you have these symptoms may worsen the symptoms and prolong the recovery time.

    If you’ve had the flu or another respiratory illness that caused a high fever, make sure your temperature is back to normal before getting back to exercise. Exercising raises your body temperature, so if you already have a fever, your temperature will become high quicker, which makes you sicker.

    If you have COVID or other contagious illnesses, stay at home, rest and isolate yourself from others.

    When you’re sick and feel weak, don’t force yourself to exercise. Focus instead on getting plenty of rest. This may actually shorten the time it takes to recover and resume your normal workout routine.

    I’ve been sick for a few weeks. What has happened to my strength and fitness?

    You may think taking two weeks off from training is disastrous, and worry you’ll lose the gains you’ve made in your previous workouts. But it could be just what the body needs.

    It’s true that almost all training benefits are reversible to some degree. This means the physical fitness that you have built up over time can be lost without regular exercise.

    To study the effects of de-training on our body functions, researchers have undertaken “bed rest” studies, where healthy volunteers spend up to 70 days in bed. They found that V̇O₂max (the maximum amount of oxygen a person can use during maximal exercise, which is a measure of aerobic fitness) declines 0.3–0.4% a day. And the higher pre-bed-rest V̇O₂max levels, the larger the declines.

    In terms of skeletal muscles, upper thigh muscles become smaller by 2% after five days of bed rest, 5% at 14 days, and 12% at 35 days of bed rest.

    Muscle strength declines more than muscle mass: knee extensor muscle strength gets weaker by 8% at five days, 12% at 14 days and more than 20% after around 35 days of bed rest.

    This is why it feels harder to do the same exercises after resting for even five days.

    Man sits on the side of his bed
    In bed rest studies, participants don’t get up. But they do in real life. Olly/Pexels

    But in bed rest studies, physical activities are strictly limited, and even standing up from a bed is prohibited during the whole length of a study. When we’re sick in bed, we have some physical activities such as sitting on a bed, standing up and walking to the toilet. These activities could reduce the rate of decreases in our physical functions compared with study participants.

    How to ease back into exercise

    Start with a lower-intensity workout initially, such as going for a walk instead of a run. Your first workout back should be light so you don’t get out of breath. Go low (intensity) and go slow.

    Gradually increase the volume and intensity to the previous level. It may take the same number of days or weeks you rested to get back to where you were. If you were absent from an exercise routine for two weeks, for example, it may require two weeks for your fitness to return to the same level.

    If you feel exhausted after exercising, take an extra day off before working out again. A day or two off from exercising shouldn’t affect your performance very much.

    Ken Nosaka, Professor of Exercise and Sports Science, Edith Cowan University

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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