Lifespan – by Dr. David Sinclair

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Some books on longevity are science-heavy and heavy-going; others are glorified manifestos with much philosophy but little practical.

This one’s a sciencey-book written for a lay reader. It’s heavily referenced, but not a challenging read.

This book is divided into three parts:

  1. What we know (the past)
  2. What we’re learning (the present)
  3. Where we’re going (the future)

Let us quickly mention: the last part is principally sociology and economics, which are not the author’s wheelhouse. Some readers may enjoy his thoughts regardless, but we’re going to concentrate on where we found the real value of the book to be: in the first and second parts, where he brings his expertise to bear.

The first part lays the foundational knowledge that’s critical for understanding why the second part is so important.

Basically: aging is a genetic disease, and diseases can be cured. No disease has magical properties, even if sometimes it can seem for a while like they do, until we understand them better.

The second part covers a lot of recent and contemporary research into aging. We learn about such things as NAD-agonists that make elderly mice biologically young again, and the Greenland shark that easily lives for 500 years or so (currently the record-holder for vertebrates). And of course, biologically immortal jellyfish.

It’s not all animal studies though…

We learn of how NAD-agonists such as NMN have been promising in human studies too, along with resveratrol and the humble diabetes drug, metformin. These things alone may have the power to extend healthy life by 20%

Other recommendations pertain to lifestyle; the usual five things (diet, exercise, sleep, no alcohol, no smoking), as well as intermittent fasting and cryotherapy (cold showers/baths).

Bottom line: this book is informative and inspiring, and if you’ve been looking for an “in” to understanding the world of biogerontology and/or anti-aging research, this is it.

Get your copy of “Lifespan: Why We Age—And Why We Don’t Have To” from Amazon today!

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  • 5 Stretches To Relieve The Pain From Sitting & Poor Posture

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    Sitting is not good for the health, yes often it’s a necessity of modern life, especially if driving. To make things worse, it can often be difficult to remember to maintain good posture the rest of the time, if it’s not a habit. So, while reducing sitting and improving posture are both very good things to do, here are 5 stretches to mitigate the damage meanwhile:

    Daily doses:

    These are best done at a rate of 2–3 sets daily:

    Cat-Cow Stretch:

    • Benefits: eases spinal tension, boosts flexibility, improves posture.
    • How to: start on all fours, alternate between arching and rounding your back while syncing with your breath (10-15 times).

    Butterfly Stretch:

    • Benefits: loosens tight hips, improves lower back flexibility, and enhances mobility for activities like squats.
    • How to: sit with soles of feet together, let knees fall toward the floor, lean forward slightly, and hold for 30 seconds to 1 minute.

    Supine Twist:

    • Benefits: unlocks the spine, relieves post-workout tension, and relaxes the shoulders and hips.
    • How to: lie on your back, bend knees, twist to one side while keeping shoulders grounded, and hold for 30 seconds to 1 minute per side.

    Calf Stretch:

    • Benefits: improves ankle mobility, loosens tight calves, and prevents injuries like Achilles tendinitis.
    • How to: stand facing a wall, extend one leg back with the heel on the ground, lean into the stretch, or use a step for deeper stretches. Hold for 30 seconds to 1 minute per leg.

    Child’s Pose:

    • Benefits: decompresses the spine, relaxes hips, and relieves tension in back and thighs.
    • How to: start on hands and knees, sit back onto your heels, stretch arms forward, and rest forehead on the mat. Hold for 30 seconds to 1 minute.

    For more on each of these, plus visual demonstrations, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like:

    10 Tips To Reduce Morning Pain & Stiffness With Arthritis

    Take care!

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  • How to be kind to yourself (without going to a day spa)

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    “I have to be hard on myself,” Sarah told me in a recent telehealth psychology session. “I would never reach my potential if I was kind and let myself off the hook.”

    I could empathise with this fear of self-compassion from clients such as Sarah (not her real name). From a young age, we are taught to be kind to others, but self-kindness is never mentioned.

    Instead, we are taught success hinges on self-sacrifice. And we need a healthy inner critic to bully us forward into becoming increasingly better versions of ourselves.

    But research shows there doesn’t have to be a trade-off between self-compassion and success.

    Self-compassion can help you reach your potential, while supporting you to face the inevitable stumbles and setbacks along the way.

    What is self-compassion?

    Self-compassion has three key ingredients.

    1. Self-kindness

    This involves treating yourself with the same kindness you would extend towards a good friend – via your thoughts, feelings and actions – especially during life’s difficult moments.

    For instance, if you find yourself fixating on a minor mistake you made at work, self-kindness might involve taking a ten-minute walk to shift focus, and reminding yourself it is OK to make mistakes sometimes, before moving on with your day.

    2. Mindfulness

    In this context, mindfulness involves being aware of your own experience of stress or suffering, rather than repressing or avoiding your feelings, or over-identifying with them.

    Basically, you must see your stress with a clear (mindful) perspective before you can respond with kindness. If we avoid or are consumed by our suffering, we lose perspective.

    3. Common humanity

    Common humanity involves recognising our own experience of suffering as something that unites us as being human.

    For instance, a sleep-deprived parent waking up (for the fourth time) to feed their newborn might choose to think about all the other parents around the world doing exactly the same thing – as opposed to feeling isolated and alone.

    It’s not about day spas, or booking a manicure

    When Sarah voiced her fear that self-compassion would prevent her success, I explained self-compassion is distinct from self-indulgence.

    “So is self-compassion just about booking in more mani/pedis?” Sarah asked.

    Not really, I explained. A one-off trip to a day spa is unlikely to transform your mental health.

    Instead, self-compassion is a flexible psychological resilience factor that shapes our thoughts, feelings and actions.

    It’s associated with a suite of benefits to our wellbeing, relationships and health.

    Massage therapist massaging woman's back
    A one-off trip to a day spa is unlikely to transform your mental health.
    baranq/Shutterstock

    What does the science say?

    Over the past 20 years, we’ve learned self-compassionate people enjoy a wide range of benefits. They tend to be happier and have fewer psychological symptoms of distress.

    Those high on self-compassion persevere following a failure. They say they are more motivated to overcome a personal weakness than those low on self-compassion, who are more likely to give up.

    So rather than feeling trapped by your inadequacies, self-compassion encourages a growth mindset, helping you reach your potential.

    However, self-compassion is not a panacea. It will not change your life circumstances or somehow make life “easy”. It is based on the premise that life is hard, and provides practical tools to cope.

    It’s a factor in healthy ageing

    I research menopause and healthy ageing and am especially interested in the value of self-compassion through menopause and in the second half of life.

    Because self-compassion becomes important during life’s challenges, it can help people navigate physical symptoms (for instance, menopausal hot flushes), life transitions such as divorce, and promote healthy ageing.

    I’ve also teamed up with researchers at Autism Spectrum Australia to explore self-compassion in autistic adults.

    We found autistic adults report significantly lower levels of self-compassion than neurotypical adults. So we developed an online self-compassion training program for this at-risk population.

    Three tips for self-compassion

    You can learn self-compassion with these three exercises.

    1. What would you say to a friend?

    Think back to the last time you made a mistake. What did you say to yourself?

    If you notice you’re treating yourself more like an enemy than a friend, don’t beat yourself up about it. Instead, try to think about what you might tell a friend, and direct that same friendly language towards yourself.

    2. Harness the power of touch

    Soothing human touch activates the parasympathetic “relaxation” branch of our nervous system and counteracts the fight or flight response.

    Specifically, self-soothing touch (for instance, by placing both hands on your heart, stroking your forearm or giving yourself a hug) reduces cortisol responses to psychosocial stress.

    Middle-aged man hugging himself
    Yes, hugging yourself can help.
    http://krakenimages.com/Shutterstock

    3. What do I need right now?

    Sometimes, it can be hard to figure out exactly what self-compassion looks like in a given moment. The question “what do I need right now” helps clarify your true needs.

    For example, when I was 37 weeks pregnant, I woke up bolt awake one morning at 3am.

    Rather than beating myself up about it, or fretting about not getting enough sleep, I gently placed my hands on my heart and took a few deep breaths. By asking myself “what do I need right now?” it became clear that listening to a gentle podcast/meditation fitted the bill (even though I wanted to addictively scroll my phone).The Conversation

    Lydia Brown, Senior Lecturer in Psychology, The University of Melbourne

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Dates vs Figs – Which is Healthier?

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    Our Verdict

    When comparing dates to figs, we picked the dates.

    Why?

    Dates are higher in sugar, but also have a lower glycemic index than figs, which makes the sugar content much healthier. On the flipside, figs do have around 3x more fiber.

    So far, so balanced.

    When it comes to micronutrients though, dates take the prize much more clearly.

    Dates have slightly more of most vitamins, and a lot more of most minerals.

    In particular, dates are several times higher in copper, iron, magnesium, manganese, phosphorus, selenium, and zinc.

    As for other phytochemical benefits going on:

    • both are good against diabetes for reasons beyond the macros
    • both have anti-inflammatory properties
    • dates have anticancer properties
    • dates have kidney-protecting properties

    So in this last case, another win for dates.

    Both are still great though, so do enjoy both!

    Want to learn more?

    You might like to read:

    Which Sugars Are Healthier, And Which Are Just The Same?

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  • 7 Signs of Undiagnosed Autism in Adults

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    When it comes to adults and autism, there are two kinds of person in the popular view: those who resemble the Rain Man, and those who are making it up. But, it’s not so, as Paul Micallef explains:

    The signs

    We’ll not keep them a mystery; they are:

    1. Social interaction difficulties: such a person may struggle with understanding social cues, leading to awkwardness, isolation, or appearing eccentric.
    2. Need for structure and routine: either highly structured or disorganized, both of which stem from executive function challenges. The former, of course, is a coping mechanism, while the latter is the absence of same.
    3. Sensory sensitivities: can include sensitivities or insensitivities to light, sound, temperature, smells, tastes, and so forth.
    4. Spiky skillset: extreme strengths in certain areas, coupled with significant difficulties in others, leading to uneven abilities. May be able to dismantle and rebuild a PC, while not knowing how to arrange an Über.
    5. Emotional regulation issues: experiences of meltdowns, shutdowns, or withdrawal as coping mechanisms when overwhelmed. Not that this is “or”, not necessarily “and”. The latter goes especially unnoticed as an emotional regulation issue, because for everyone else, it’s something that’s not there to see.
    6. Unusual associations: making mental connections or associations that seem random or uncommon compared to others. The mind went to 17 places quickly and while everyone else got from idea A to idea B, this person is already at idea Q.
    7. Being “just different”: a general sense of being the odd one out, standing out in subtle or distinct ways. This is rather a catch-all, but if there’s someone who fits this, there’s a good chance, the other things apply too.

    For more on all of these, whether pertaining to yourself or a loved one (or both!), enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like to read:

    Take care!

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  • Next-Level Headache Hacks

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    A Muscle With A Lot Of Therapeutic Value

    First, a quick anatomy primer, so that the rest makes sense. We’re going to be talking about your sternocleidomastoid (SCM) muscle today.

    To find it, there are two easy ways:

    • look in a mirror, turn your head to one side and it’ll stick out on the opposite side of your neck
    • look at this diagram

    (we’re going to talk about it in the singular, but you have one on each side)

    This muscle is interesting for very many reasons, but what we’re going to focus on today is that massaging/stretching it (correctly!) can benefit several things that are right next to it and/or behind it, namely:

    • The tenth cranial nerve
    • The eleventh cranial nerve
    • The carotid artery

    Why do we care about these?

    Well, we would die quickly without the first and last of those. However, more practically, massaging each has benefits:

    The tenth cranial nerve

    This one is also known by its superhero alter-ego name:

    The Vagus Nerve (And How You Can Make Use Of It)

    The eleventh cranial nerve

    This one’s not nearly so critical to life, but it does facilitate most of the motor functions in that general part of the body—including some mechanics of speech production, and maintaining posture of the shoulders/neck/head (which in turn strongly affects presence/absence of certain kinds of headaches).

    The carotid artery

    We suspect you know what this one does already; it supplies the brain (and the rest of your head, for that matter) with oxygenated blood.

    What is useful to know today, is that it can be massaged, via the SCM, in a way that brings about a gentler version of this “one weird trick” to cure a lot of kinds of headaches:

    Curing Headaches At Home With Actual Science

    How (And Why) To Massage Your SCM

    …to relieve many kinds of headache, migraine, eye-ache, and tension or pain the jaw. It’s not a magical cure all so this comes with no promises, but it can and will help with a lot of things.

    In few words: turn your ahead away from the side where it hurts (if both, just pick one and then repeat for the other side), and slightly downwards. When your SCM sticks out a bit on the other side, gently pinch and rub it, working from the bottom to the top.

    If you prefer videos, here is a demonstration:

    !

    How (And Why) To Stretch Your SCM

    The above already includes a little stretch, but you can stretch it in a way that specifically stimulates your vagus nerve (this is good for many things).

    In few words: stand (or sit) up straight, and interlace your fingers together. Put your hands on the back of your neck, thumbs-downwards, and (keeping your face forward) look to one side with your eyes only, and hold that until you feel the urge to yawn (it’ll probably take between about 3 seconds and 30 seconds). Then repeat on the other side.

    If you prefer videos, this one is a very slight variation of what we just described but works the same way:

    !

    Take care!

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  • Future-Proof Your Brain

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    This is Kimberly Wilson. She’s a psychologist, not a doctor, and/but her speciality is neurophysiology and brain health.

    Here’s what she wants us to know…

    Avoid this very common killer

    As you’re probably aware, the #1 killer in the US is heart disease, followed by COVID, which effectively pushed everything down a place. Thereafter, we see cancer, followed by accidental injuries, stroke, and dementia (including Alzheimer’s).

    Over in the UK, where Wilson is from, dementia (including Alzheimer’s disease) is the #1 killer, followed by heart disease and then respiratory diseases (including COVID), and then stroke, then cancer.

    As ever, what’s good for the heart is good for the brain, so many of the same interventions will help avoid both. With regard to some of the other differences in order, the reasons are mostly due to differences in the two countries’ healthcare systems and firearms laws.

    It’s worth noting, though, that the leading cause of death in young people (aged 15–19) is suicide in the UK; in the US it’s nominally accidental injuries first (e.g. accidental shootings) with intentional suicide in the second spot.

    In other words… Young or old, mental health is a serious health category that kills literally the most people in the UK, and also makes the top spots in the US.

    Avoid the early killer

    Given the demographics of most of our readership, chances are you’ve already lived past your teens and twenties. That’s not to say that suicide is no longer a risk, though, and it’s also worth noting that while mental health issues are invisible, they’re still physical illnesses (the brain is also an organ, after all!), so this isn’t something where you can simply “decide not to” and that’s you set, safe for life. So, please do continue to take good care in that regard.

    We wrote about this previously, here:

    How To Stay Alive (When You Really Don’t Want To)

    Avoid the later killer

    Wilson talks about how a recent survey found that…

    • while nearly half of adults say dementia is the disease they fear most,
    • only a third of those thought you could do anything to avoid it, and
    • just 1% could name the 7 known risk factors.

    Quick test: can you name the 7 known risk factors?

    Please take a moment to actually try (this kind of mental stimulation is good in any case), and count them out on your fingers (or write them down), and then

    When you’re ready: click here to see the answer!

    How many did you get? If you got them all, well done. If not, then well, now you know, so that’s good.

    So, with those 7 things in mind, the first obvious advice is to take care of those things.

    Taking an evidence-based medicine approach, Wilson recommends some specific interventions that will each improve one or more of those things, directly or indirectly:

    Eating right

    Wilson is a big fan of “nutritional psychiatry” and feeding one’s brain properly. We wrote about this, here:

    The 6 Pillars Of Nutritional Psychiatry

    As well as agreeing with the obvious “eat plenty of fiber, different-colored plants, and plenty of greens and beans”, Wilson specifically also champions getting enough of vitamins B9, B12, and D, as well as getting a healthy dose of omega-3 fatty acids.

    She also recommends intermittent fasting, if that’s a reasonable option for you—but advocates for not worrying about it, if it’s not easy for you. For example, if you are diabetic, or have (or have a history with) some kind of eating disorder(s), then it’s probably not usefully practicable. But for most people, it can reduce systemic inflammation, which means also reducing neuroinflammation.

    Managing stress right

    Here she advocates for three main things:

    1. Mindful meditation (see: Evidence-Based, No-Frills Mindfulness)
    2. Psychological resilience (see: Building Psychological Resilience)
    3. Mindful social media use (see: Making Social Media Work For Your Mental Health)

    Managing money right

    Not often we talk about this in a health science publication as opposed to a financial planning publication, but the fact is that a lot of mental distress, which goes on to have a huge impact on the brain, is rooted in financial stresses.

    And, of course, it’s good to be able to draw on financial resources to directly fund one’s good health, but that is the secondary consideration here—the financial stress is the biggest issue, and you can’t CBT your way out of debt, for example.

    Therapists often face this, and what has been referred to informally by professionals in the field as “Shit Life Syndrome”—and there’s only so much that therapy can do about that.

    We’re not a financial publication, but one recommendation we’ll drop is that if you don’t currently have budgeting software that you use, this writer personally uses and swears by YNAB (You Need A Budget), so maybe check that out if you don’t already have everything covered in that regard. It’s not free, but there is a 34-day free trial.

    Therapy can be very worthwhile nonetheless

    Wilson notes that therapy is like non-invasive brain surgery (because of neuroplasticity, it’s literally changing physical things in your brain).

    It’s not a magic bullet and it’s not the right choice for everyone, but it’s worth considering, and even self-therapy can yield benefits for many:

    The Gym For Your Mental Health: Getting The Most Out Of Therapy

    Sleeping right

    Sleep is not only critical for health in general and brain health in particular, it’s also most of when our glymphatic system does clean-up in the brain (essential for avoiding Alzheimer’s & Parkinson’s, amongst other diseases):

    How To Clean Your Brain (Glymphatic Health Primer)

    Want to know more from Kimberley Wilson?

    We reviewed a book of hers recently, here:

    Unprocessed: What your Diet Is Doing To Your Brain – by Kimberley Wilson

    However, much of what we shared today was sourced from another book of hers that we haven’t reviewed yet but probably will do one of these days:

    How to Build a Healthy Brain: Reduce stress, anxiety and depression and future-proof your brain – by Kimberley Wilson

    Enjoy!

    Don’t Forget…

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