GABA Against Stress/Anxiety
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A Neurotransmitter Less Talked-About
GABA is taken by many people as a supplement, mostly as a mood modifier, though its health claims go beyond the recreational—and also, we’re of the opinion that mental health is also just health, and if it works, it works. We’ll explore some of the claims and science behind them today…
What is GABA?
GABA stands for gamma-aminobutyric acid, and it’s a neurotransmitter. It’s a lot less talked-about than for example dopamine or serotonin, but it’s very important nonetheless.
We make it ourselves inside our body, and we can also get it from our food, or supplement it, and some drugs will also have an effect on its presence and/or activity in our body.
What foods is it found in?
- Animals, obviously (just like in human brains*)
- Fermented foods (many kinds)
- Yeast
- Tea
- Tomatoes
- Mulberries
For more details, see:
γ-Aminobutyric acid found in fermented foods and beverages: current trends
*However, we do not recommend eating human brains, due to the risk of CJD and prion diseases in general.
What claims are made about it and are they true?
For brevity, we’ll give a little spoiler up-front: all the popular claims for it appear to be valid, though there’s definitely room for a lot more human trials (we skipped over a lot of rodent studies today!).
So we’ll just drop some of its main benefits, and human studies to back those.
Reduction of stress and anxiety
GABA decreases task-related stress and anxiety within 30 minutes of being taken, both in subjective measures (i.e., self-reports) and in objective clinical physiological measures:
Cognitive enhancement
It’s not a does-everything nootropic like some, but it does have clear benefits to episodic memory:
❝GABA intake might help to distribute limited attentional resources more efficiently, and can specifically improve the identification and ordering of visual events that occur in close temporal succession❞
One of the things that makes this one important is that it also deals with the often-asked question of “does GABA pass the blood-brain barrier”:
❝The present findings do give further credence to the idea that oral ingestion does allow GABA to reach the brain and exert direct effects on cognition, which in the present case were specific to temporal attention.❞
Read more:
Supplementation of gamma-aminobutyric acid (GABA) affects temporal, but not spatial visual attention
Potential for more
We take care to give good quality sources, so the following study comes with a big caveat that it has since been retracted. Why was it retracted, you wonder?
It’s about the sample; they cite “30 healthy adults”, but neglected tp mention that this figure was initially 46. What happened to the other 16 participants is unclear, but given that this was challenged and the challenge not answered, it was sufficient for the journal (Nature) to pull the study, in case of deliberate sample bias.
However! Running the numbers in their results section, a probability of 0.03 is very compelling unless the disappearance of 16 subjects was outright fraudulent (which we regrettably cannot know either way).
Here’s the study (so take it with a pinch of salt, considering the above), and taken at face value, it shows how GABA supplementation improves accurate reactions to fast-moving visual and auditory stimuli:
RETRACTED ARTICLE: γ-Aminobutyric acid (GABA) administration improves action selection processes: a randomised controlled trial
…so, hopefully this experiment will be repeated, without disappearing participants!
The sweet spot
You may be wondering how something that slows a person down (having a relaxing effect) can also speed a person up. This has to do with what it is and isn’t affecting; think of it like a “focus mode” on your computer or other device that greys-out everything else a bit so that you can focus on what you’re doing.
It’s in some ways (by different neurochemical pathways, though) a similar effect to the “relaxed alertness” created by l-theanine supplementation.
There’s also a sweet spot whereby GABA is toning some things down just the right amount, without adversely affecting performance in areas we don’t want slowed down. For the science of this, see:
Is it safe?
GABA is “Generally Recognized As Safe”. However:
- you should speak with your pharmacist if you are taking any medications for blood pressure or epilepsy, as GABA supplementation may cause them to work too well.
- you should absolutely not take GABA with alcohol or opioids as (dose-dependent for all the substances involved, and also depending on your metabolic base rate and other factors) its acute depression of the CNS can mean you relax and slow down too much, and you may find yourself not breathing often enough to sustain life.
Aside from that, it is considered safe up to at least 1g/kg/day*. Given that popular doses are 120–750mg, and most people weigh more than 750g, this is very safe for most people:
United States Pharmacopeia (USP) Safety Review of Gamma-Aminobutyric Acid (GABA)
Where can I get it?
We don’t sell it, but for your convenience, here’s an example product on Amazon
Enjoy!
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Resistance band Training – by James Atkinson
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For those who’d like a full gym workout at home, without splashing out thousands on a home gym, resistance bands provide a lot of value. But how much value, really?
As James Atkinson demonstrates, there’s more exercise available than one might think.
Did you know that you can use the same band to strengthen your triceps as well as your biceps, for instance? and the same goes for your quadriceps and biceps femoris. And core strength? You bet.
The style here is not a sales pitch (though he does, at the end, offer extra resources if desired), but rather, instructional, and this book is in and of itself already a complete guide. With clear instructions and equally clear illustrations, you don’t need to spend a dime more (unless you don’t own a resistance band, in which case then yes, you will need one of those).
Bottom line: if you’d like to give your body the workout it deserves, this book is a potent resource.
Click here to check out Resistance Band Training, and get training!
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The Wim Hof Method – by Wim Hof
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In Wednesday’s main feature, we wrote about the Wim Hof Method, and/but only scratched the surface. Such is the downside of being a super-condensed newsletter! However, it does give us the opportunity to feature the book:
The Wim Hof Method is definitely loudly trumpeted as “up there” with Atomic Habits or How Not To Die in the category of “life-changing” books. Why?
Firstly, it’s a very motivational book. Hof is a big proponent of the notion “if you think you can or you think you can’t, you’re right” idea, practises what he preaches, and makes clear he’s not special.
Secondly, it’s backed up with science. While it’s not a science-heavy book and that’s not the main focus, there are references to studies. Where physiological explanations are given for how certain things work, those explanations are sound. There’s no pseudoscience here, which is especially important for a book of this genre!
What does the book have that our article didn’t? A good few things:
- More about Hof’s own background and where it’s taken him. This is generally not a reason people buy books (unless they are biographies), but it’s interesting nonetheless.
- A lot more advice, data, and information about Cold Therapy and how it can (and, he argues convincingly, should) be built into your life.
- A lot about breathing exercises that we just didn’t cover at all in our article, but is actually an important part of the Wim Hof Method.
- More about stepping through the psychological barriers that can hold us back.
Bottom line: this book offers benefits that stretch into many areas of life, from some simple habits that can be built.
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Macadamias vs Hazelnuts – Which is Healthier?
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Our Verdict
When comparing macadamias to hazelnuts, we picked the hazelnuts.
Why?
In terms of macros first, hazelnuts have 2x the protein, and slightly more carbs and fiber. We call this a win for hazelnuts.
When it comes to vitamins, macadamias have more of vitamins B1, B2, and B3, while hazelnuts have more of vitamins A, B5, B6, B7, B9, C, and E. Notably, 28x more vitamin E, so that’s not inconsiderable. Also 10x the vitamin B9, and 5x the vitamin C, and the rest, more modest wins. In any case, clearly a strong win for hazelnuts here.
In the category of minerals, macadamias have more selenium, while hazelnuts have more calcium, copper, iron, magnesium, manganese, phosphorus, potassium, and zinc. Another clear win for hazelnuts.
In short, hazelnuts win in all categories. However, by all means enjoy either or both (unless you have a nut allergy, in which case, obviously don’t).
Want to learn more?
You might like to read:
Why You Should Diversify Your Nuts
Take care!
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10 “Healthy” Foods That Are Often Worse Than You Think
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“This is healthy, it’s a…” is an easy mistake to make if one doesn’t read the labels. Here are 10 tricksters to watch out for in particular!
Don’t be fooled by healthy aesthetics on the packaging…
Notwithstanding appearances and in many cases reputations, these all merit extra attention:
- Yogurt: sweetened yogurts, especially “fruit at the bottom / in the corner” types, often have 15–30g of sugar per serving. Plain Greek yogurt is a better choice, offering 15–20g of protein with no added sugar. You can always add fresh fruits or spices like sweet cinnamon for flavor without added sugar.
- Oatmeal: prepackaged oatmeal can contain 12–15 grams of added sugar per serving, similar to a glazed donut. Additionally, finely milled oats (as in “instant” oatmeal) can cause blood sugar spikes by itself, due to the loss of fiber. Better is plain oats, and if you like, you can sweeten them naturally with sweet cinnamon and/or fresh fruit for a healthier breakfast.
- Sushi: while sushi contains nutritious fish, it often has too much white rice (and in the US, sushi rice is also often cooked with sugar to “improve” the taste and help cohesion) and sugary sauces. This makes many rolls much less healthy. So if fish (the sashimi component of sushi) is your thing, then focus on that, and minimize sugar intake for a more balanced meal.
- Baked beans: store-bought baked beans can have up to 25g of added sugar per cup, similar to soda. Better to opt for plain beans and prepare them at home so that nothing is in them except what you personally put there.
- Deli meats: deli meats are convenient but often are more processed than they look, containing preservatives linked to health risks. Fresh, unprocessed meats like chicken or turkey breast are healthier and can still be cost-effective when bought in bulk.
- Fruit juices: fruit juices lack fiber (meaning their own natural sugars also become harmful, with no fiber to slow them down) and often contain added sugars too. Eating whole fruits is a much better way to get fiber, nutrients, and controlled healthy sugar intake.
- Hazelnut spread: hazelnut spreads are usually 50% added sugar and contain unhealthy oils like palm oil. So, skip those, and enjoy natural nut butters for healthier fats and proteins.
- Granola: granola is often loaded with added sugars and preservatives, so watch out for those.
- Sports drinks: sports drinks, with 20–25g of added sugar per serving, are unnecessary and unhelpful (except, perhaps, in case of emergency for correcting diabetic hypoglycemia). Stick to water or electrolyte drinks—and even in the latter case, check the labels for added sugar and excessive sodium!
- Dark chocolate: dark chocolate with 80% or more cocoa has health benefits but still typically contains a lot of added sugar. Check labels carefully!
For more on each of these, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like to read:
From Apples to Bees, and High-Fructose Cs: Which Sugars Are Healthier, And Which Are Just The Same?
Take care!
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Natto vs Tofu – Which is Healthier?
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Our Verdict
When comparing nattō to tofu, we picked the nattō.
Why?
In other words, in the comparison of fermented soy to fermented soy, we picked the fermented soy. But the relevant difference here is that nattō is fermented whole soybeans, while tofu is fermented soy milk of which the coagulated curds are then compressed into a block—meaning that the nattō is the one that has “more food per food”.
Looking at the macros, it’s therefore no surprise that nattō has a lot more fiber to go with its higher carb count; it also has slightly more protein. You may be wondering what tofu has more of, and the answer is: water.
In terms of vitamins, nattō has more of vitamins B2, B4, B6, C, E, K, and choline, while tofu has more of vitamins A, B3, and B9. So, a 7:3 win for nattō, even before considering that that vitamin C content of nattō is 65x more than what tofu has.
When it comes to minerals, nattō has more copper, iron, magnesium, manganese, potassium, and zinc, while tofu has more calcium, phosphorus, and selenium. So, a 6:3 win for nattō, and yes, the margins of difference are comparable (being 2–3x more for most of these minerals).
In short, both of these foods are great, but nattō is better.
Want to learn more?
You might like to read:
21% Stronger Bones in a Year at 62? Yes, It’s Possible (No Calcium Supplements Needed!)
Take care!
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How To Kill Laziness
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Laziness Is A Scooby-Doo Villain.
Which means: to tackle it requires doing a Scooby-Doo unmasking.
You know, when the mystery-solving gang has the “ghost” or “monster” tied to a chair, and they pull the mask off, to reveal that there was no ghost etc, and in fact it was a real estate scammer or somesuch.
Social psychologist Dr. Devon Price wrote about this (not with that metaphor though) in a book we haven’t reviewed yet, but will one of these days:
Laziness Does Not Exist – by Dr. Devon Price (book)
In the meantime, and perhaps more accessibly, he gave a very abridged summary for Medium:
Medium | Laziness Does Not Exist… But unseen barriers do (11mins read)
Speaking of barriers, Medium added a paywall to that (the author did not, in fact, arrange the paywall as Medium claim), so in case you don’t have an account, he kindly made the article free on its own website, here:
Devon Price | Laziness Does Not Exist… But unseen barriers do (same article; no paywall)
He details problems that people get into (ranging from missed deadlines to homelessness), that are easily chalked up to laziness, but in fact, these people are not lazily choosing to suffer, and are usually instead suffering from all manner of unchosen things, ranging from…
- imposter syndrome / performance anxiety,
- perfectionism (which can overlap a lot with the above),
- social anxiety and/or depression (these also can overlap for some people),
- executive dysfunction in the brain, and/or
- just plain weathering “the slings and arrows of outrageous fortune [and] the heartache and the thousand natural shocks that flesh is heir to”, to borrow from Shakespeare, in ways that aren’t always obviously connected—these things can be great or small, it could be a terminal diagnosis of some terrible disease, or it could be a car breakdown, but the ripples spread.
And nor are you, dear reader, choosing to suffer (even if sometimes it appears otherwise)
Unless you’re actually a masochist, at least, in which case, you do you. But for most of us, what can look like laziness or “doing it to oneself” is usually a case of just having one or more of the above-mentioned conditions in place.
Which means…
That grace we just remembered above to give to other people?
Yep, we should give that to ourselves too.
Not as a free pass, but in the same way we (hopefully) would with someone else, and ask: is there some problem I haven’t considered, and is there something that would make this easier?
Here are some tools to get you started:
- Imposter Syndrome (And Why Almost Everyone Has It)
- Perfectionism, And How To Make Yours Work For You
- How To Set Anxiety Aside
- Mental Health First-Aid (To Get Yourself Or A Loved One Through Depression)
- Procrastination, And How To Pay Off The To-Do List Debt
- Take This Two-Minute Executive Dysfunction Test
Take care!
Don’t Forget…
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