Eyes for Alzheimer’s Diagnosis: New?

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It’s Q&A Time!

This is the bit whereby each week, we respond to subscriber questions/requests/etc

Have something you’d like to ask us, or ask us to look into? Hit reply to any of our emails, or use the feedback widget at the bottom, and a Real Human™ will be glad to read it!

Q: As I am a retired nurse, I am always interested in new medical technology and new ways of diagnosing. I have recently heard of using the eyes to diagnose Alzheimer’s. When I did some research I didn’t find too much. I am thinking the information may be too new or I wasn’t on the right sites.

(this is in response to last week’s piece on lutein, eyes, and brain health)

We’d readily bet that the diagnostic criteria has to do with recording low levels of lutein in the eye (discernible by a visual examination of macular pigment optical density), and relying on the correlation between this and incidence of Alzheimer’s, but we’ve not seen it as a hard diagnostic tool as yet either—we’ll do some digging and let you know what we find! In the meantime, we note that the Journal of Alzheimer’s Disease (which may be of interest to you, if you’re not already subscribed) is onto this:

Read: Cognitive Function and Its Relationship with Macular Pigment Optical Density and Serum Concentrations of its Constituent Carotenoids

See also:

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  • Clean – by Dr. James Hamblin

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    Our skin is our largest organ, and it’s easy to forget that, and how much it does for us. All things considered, it’s good to take good care of it! But what if we sometimes take too much “care” of it?

    Dr. James Hamblin, a medical doctor-turned-writer, has explored this a lot both personally and in research. Through such, he has come to the conclusion there’s definitely a “sweet spot” of personal hygiene:

    • Too little, and the Bubonic plague sweeps through Europe, or other plagues sweep through other places when European invaders came.
    • Too much, and we strip our skin of one of its greatest qualities: the ability to protect us.

    Dr. Hamblin asks (and answers) such questions as:

    • What is good hygiene, and what is neurotically doing ourselves multiple levels of harm because advertising companies shamed us into doing so?
    • Is it good or bad to use a series of products, each to undo the problem caused by the previous?
    • What the difference between a 5-step skincare routine, and a series of gratuitous iatrogenic damage?
    • Which products clean us most helpfully, and which clean us most harmfully?
    • How often should we bathe/shower, really?

    If the book has a weak point, it’s that it’s written mostly with his body in mind. That makes a difference when it comes to hairwashing, for example. He’s a white guy with short hair. If you’re black and/or have long hair, for example, your haircare needs will be quite different. Similarly, many women engage in shaving/depilation in places that most men don’t, and the consequences of that choice (and implications for any extra washing needs/harms) aren’t covered.

    Bottom line: notwithstanding the aforementioned blind-spots, this book will help readers reduce the amount of harm we are doing to our bodies with our washing routines, without sacrificing actual hygiene.

    Click here to check out Clean and help your skin to help you!

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  • The Modern Art and Science of Mobility – by Aurélien Broussal-Derval

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    We’ve reviewed mobility books before, so what makes this one stand out?

    We’ll be honest: the illustrations are lovely.

    The science, the information, the exercises, the routines, the programsAll these things are excellent too, but these can be found in many a book.

    What can’t usually be found is very beautiful (yet no less clear) watercolor paintings and charcoal sketches as anatomical illustrations.

    There are photos too (also of high quality), but the artistry of the paintings and sketches is what makes the reader want to spend time perusing the books.

    At least, that’s what this reviewer found! Because it’s all very well having access to a lot of information (and indeed, I read so much), but making it enjoyable increases the chances of rereading it much more often.

    As for the rest of the content, the book’s information is divided in categories:

    1. Pain (what causes it, what it means, and how to manage it)
    2. Breathing (yes, a whole section devoted to this, and it is aligned heavily to posture also, as well as psychological state and the effect of stress on tension, inflammation, and more)
    3. Movement (this is mostly about kinds of movement and ranges of movement)
    4. Mobility (this is about aggregating movements as a fully mobile human)

    So, each builds on from the previous because any pain needs addressing before anything else, breathing (and with it, posture) comes next, then we learn about movement, then we bring it all together for mobility.

    Bottom line: this is a beautiful and comprehensive book that will make learning a joy

    Click here to check out The Modern Art and Science of Mobility, and learn and thrive!

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  • The Many Faces Of Cosmetic Surgery

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    Cosmetic Surgery: What’s The Truth?

    In Tuesday’s newsletter, we asked you your opinion on elective cosmetic surgeries, and got the above-depicted, below-described, set of responses:

    • About 48% said “Everyone should be able to get what they want, assuming informed consent”
    • About 28% said “It can ease discomfort to bring features more in line with normalcy”
    • 15% said “They should be available in the case of extreme disfigurement only”
    • 10% said “No elective cosmetic surgery should ever be performed; needless danger”

    Well, there was a clear gradient of responses there! Not so polarizing as we might have expected, but still enough dissent for discussion

    So what does the science say?

    The risks of cosmetic surgery outweigh the benefits: True or False?

    False, subjectively (but this is important).

    You may be wondering: how is science subjective?

    And the answer is: the science is not subjective, but people’s cost:worth calculations are. What’s worth it to one person absolutely may not be worth it to another. Which means: for those for whom it wouldn’t be worth it, they are usually the people who will not choose the elective surgery.

    Let’s look at some numbers (specifically, regret rates for various surgeries, elective/cosmetic or otherwise):

    • Regret rate for elective cosmetic surgery in general: 20%
    • Regret rate for knee replacement (i.e., not cosmetic): 17.1%
    • Regret rate for hip replacement (i.e., not cosmetic): 4.8%
    • Regret rate for gender-affirming surgeries (for transgender patients): 1%

    So we can see, elective surgeries have an 80–99% satisfaction rate, depending on what they are. In comparison, the two joint replacements we mentioned have a 82.9–95.2% satisfaction rate. Not too dissimilar, taken in aggregate!

    In other words: if a person has studied the risks and benefits of a surgery and decides to go ahead, they’re probably going to be happy with the results, and for them, the benefits will have outweighed the risks.

    Sources for the above numbers, by the way:

    But it’s just a vanity; therapy is what’s needed instead: True or False?

    False, generally. True, sometimes. Whatever the reasons for why someone feels the way they do about their appearance—whether their face got burned in a fire or they just have triple-J cups that they’d like reduced, it’s generally something they’ve already done a lot of thinking about. Nevertheless, it does also sometimes happen that it’s a case of someone hoping it’ll be the magical solution, when in reality something else is also needed.

    How to know the difference? One factor is whether the surgery is “type change” or “restorative”, and both have their pros and cons.

    • In “type change” (e.g. rhinoplasty), more psychological adjustment is needed, but when it’s all over, the person has a new nose and, statistically speaking, is usually happy with it.
    • In “restorative” (e.g. facelift), less psychological adjustment is needed (as it’s just a return to a previous state), so a person will usually be happy quickly, but ultimately it is merely “kicking the can down the road” if the underlying problem is “fear of aging”, for example. In such a case, likely talking therapy would be beneficial—whether in place of, or alongside, cosmetic surgery.

    Here’s an interesting paper on that; the sample sizes are small, but the discussion about the ideas at hand is a worthwhile read:

    Does cosmetic surgery improve psychosocial wellbeing?

    Some people will never be happy no matter how many surgeries they get: True or False?

    True! We’re going to refer to the above paper again for this one. In particular, here’s what it said about one group for whom surgeries will not usually be helpful:

    ❝There is a particular subgroup of people who appear to respond poorly to cosmetic procedures. These are people with the psychiatric disorder known as “body dysmorphic disorder” (BDD). BDD is characterised by a preoccupation with an objectively absent or minimal deformity that causes clinically significant distress or impairment in social, occupational, or other areas of functioning.

    For several reasons, it is important to recognise BDD in cosmetic surgery settings:

    Firstly, it appears that cosmetic procedures are rarely beneficial for these people. Most patients with BDD who have had a cosmetic procedure report that it was unsatisfactory and did not diminish concerns about their appearance.

    Secondly, BDD is a treatable disorder. Serotonin-reuptake inhibitors and cognitive behaviour therapy have been shown to be effective in about two-thirds of patients with BDD❞

    ~ Dr. David Castle et al. (lightly edited for brevity)

    Which is a big difference compared to, for example, someone having triple-J breasts that need reducing, or the wrong genitals for their gender, or a face whose features are distinct outliers.

    Whether that’s a reason people with BDD shouldn’t be able to get it is an ethical question rather than a scientific one, so we’ll not try to address that with science.

    After all, many people (in general) will try to fix their woes with a haircut, a tattoo, or even a new sportscar, and those might sometimes be bad decisions, but they are still the person’s decision to make.

    And even so, there can be protectionist laws/regulations that may provide a speed-bump, for example:

    Thinking about cosmetic surgery? New standards will force providers to tell you the risks and consider if you’re actually suitable

    Take care!

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Related Posts

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  • Apricot vs Banana – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing apricot to banana, we picked the banana.

    Why?

    Both are great, and it was close!

    In terms of macros, apricot has more protein, while banana has more carbs and fiber; both are low glycemic index foods, and we’ll call this category a tie.

    In the category of vitamins, apricot has more of vitamins A, C, E, and K, while banana has more of vitamins B1, B2, B3, B5, B6, B7, B9, and choline, giving banana the win by strength of numbers. It’s worth noting though that apricots are one of the best fruits for vitamin A in particular.

    When it comes to minerals, apricot has slightly more calcium, iron, and zinc, while banana has a lot more magnesium, manganese, potassium, and selenium, meaning a moderate win for banana here.

    Adding up the sections makes for an overall win for banana—but of course, by all means enjoy either or both!

    Want to learn more?

    You might like to read:

    Top 8 Fruits That Prevent & Kill Cancer ← we argue for apricots as bonus number 9 on the list

    Take care!

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  • The Problem With Sweeteners

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    The WHO’s view on sugar-free sweeteners

    The WHO has released a report offering guidance regards the use of sugar-free sweeteners as part of a weight-loss effort.

    In a nutshell, the guidance is: don’t

    They make for interesting reading, so if you don’t have time now, you might want to just quickly open and bookmark them for later!

    Some salient bits and pieces:

    Besides that some sweeteners can cause gastro-intestinal problems, a big problem is desensitization:

    Because many sugar substitutes are many times (in some cases, hundreds of times) sweeter than sugar, this leads to other sweet foods tasting more bland, causing people to crave sweeter and sweeter foods for the same satisfaction level.

    You can imagine how that’s not a spiral that’s good for the health!

    The WHO recommendation applies to artificial and naturally-occurring non-sugar sweeteners, including:

    • Acesulfame K
    • Advantame
    • Aspartame
    • Cyclamates
    • Neotame
    • Saccharin
    • Stevia

    Sucralose and erythritol, by the way, technically are sugars, just not “that kind of sugar” so they didn’t make the list of non-sugar sweeteners.

    That said, a recent study did find that erythritol was linked to a higher risk of heart attack, stroke, and early death, so it may not be an amazing sweetener either:

    Read: The artificial sweetener erythritol and cardiovascular event risk

    Want to know a good way of staying healthy in the context of sweeteners?

    Just get used to using less. Your taste buds will adapt, and you’ll get just as much pleasure as before, from progressively less sweetening agent.

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

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  • Why You’re Tired & How To Fix It

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    This is Sadia Badiei. A dietician by academic and professional background, she’s nowadays hung up her lab coat for a chef’s jacket, and is best known for her “Pick Up Limes” brand. Today, we’ll be taking her advice on managing energy levels with what’s on our plates!

    Quick note: our usual medical/legal disclaimer applies, and this article cannot diagnose you from afar, and thus neither can it make any certain prescription; this is for educational purposes, and aimed at being applicable to most of our readers.

    There are many possible things that can cause chronic fatigue, and not all of them can be fixed by diet. Your doctor will have access to tests and such that we, being a humble health science publication, do not.

    You may recognize her; we’ve featured her videos occasionally, mostly recently:

    Pick Up A Zest For Life: 10 Lessons For A Healthy Mind & Body

    But, what does she want us to know about living life with more energy?

    It starts with balance

    Badiei makes the case that we should strive for a nutritionally-balanced diet; that may not come as much of a revelation, but what does that look like for a vegan (Badiei advocates for plant-based eating)?

    She recommends that our diet consist of:

    • About 50% fruits and vegetables
    • About 25% grains and starches
    • About 25% proteins
    • Modest amounts of fats
    • A little of well-chosen dairy substitutions
    • Finally, a few judicious supplements to top it off

    That does add up to more than 100%, but 1) we did say “About n%” and 2) this is not a bad thing to note, actually, since Badiei advocates (as we do) for focussing more on what we add into our diet, rather than what we take out.

    Breaking it down a little further, she recommends making sure to get “the foundational seven”, which is a little like “Dr. Greger’s Daily Dozen”, but in this case it’s counted on a per-food-type basis.

    Thus, she recommends:

    1. Dark green leafy vegetables
    2. Assorted other non-starchy vegetables (your choice what kind)
    3. Fruit, of any kinds (unlike Dr. Greger separating berries)
    4. Grains and starches (so for example, potatoes are lumped in with rice here, botanically very different, but often fulfil a similar culinary role)
    5. Nuts and seeds
    6. Legumes
    7. Fortified dairy alternatives

    For full details including how much of each, and “what counts”, etc, see:

    Pick Up Limes | The Nourish Method

    Time your carbs

    Slow-release carbohydrates, those with the most fiber, are best most of the time, giving us more sustained fuel, keeping us energized for longer after meals—even if we would rather sleep:

    She cites: Fiber and Saturated Fat Are Associated with Sleep Arousals and Slow Wave Sleep

    Quick-release carbohydrates, those with what’s generally considered a less favorable carb:fiber ratio, are best if we’re going to eat nearer to bedtime. We know, eating before bed is often considered a bit of a no-no, but Badiei bids us indulge if we so desire, as the quicker-absorbed carbohydrates support tryptophan reaching our brain more efficiently, and thus promote sleep onset.

    See also: Should You Go Light Or Heavy On Carbs?

    About that fat

    We mentioned (or rather, Badiei’s citation mentioned) saturated fat. It is indeed linked with difficulty falling asleep, and/but omega-3 fatty acids, on the other hand, promote better sleep.

    She cites: The relationship between sleep duration, sleep quality and dietary intake in adults

    While you’re enjoying those nuts and seeds (for the omega-3 fatty acids), you might also note that several also star in Badiei’s list of plant-based foods that are rich in tryptophan, such as soy, cashews, pumpkin seeds, sunflower seeds, beans, green vegetables, and mushrooms.

    Micronutrients

    Badiei’s focus here is on B-vitamins, iron, magnesium, selenium, and zinc. We imagine most of our readers here are taking steps to ensure to get a full daily coverage of vitamins and minerals anyway, but you might want to read what she has to say about iron on a plant-based diet, because the numbers may be different than you think.

    The reason for this is that while animal products contain mostly heme iron, which is easier to absorb but associated with a risk increase in some diseases, plant-based foods usually* contain only non-heme iron, which is healthier but not as bioavailable, so if eating only plants, we need more of it:

    Pick Up Limes | Iron on a Plant-Based Diet

    *If you eat a carnivorous plant, guess what, it’ll have heme iron in it, tangling that food web.

    “What if I know I have chronic fatigue for non-dietary reasons?”

    Well, that sucks, and we’re not going to pretend the above will magically fix it. However, there are still things that can at least relatively improve your experience:

    Eat To Beat Chronic Fatigue! Yes, Even When Fatigued Chronically

    (it’s a good guide to being able to consistently eat healthily when your energy levels are consistently at minimal, meaning that a lot of common advice becomes unusable)

    Take care!

    Don’t Forget…

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    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails: