
Is It Dementia?
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Spot The Signs (Because None Of Us Are Immune)
Dementia affects increasingly many people, and unlike a lot of diseases, it disproportionately affects people in wealthy industrialized nations.
There are two main reasons for this:
- Longevity (in poorer countries, more people die of other things sooner; can’t get age-related cognitive decline if you don’t age)
- Lifestyle (in the age of convenience, it has never been easier to live an unhealthy lifestyle)
The former is obviously no bad thing for those of us lucky enough to be in wealthier countries (though even in such places, good healthcare access is of course sadly not a given for all).
The latter, however, is less systemic and more epidemic. But it does cut both ways:
- An unhealthy lifestyle is much easier here, yes
- A healthier lifestyle is much easier here, too!
This then comes down to two factors in turn:
- Information: knowing about dementia, what things lead to it, what to look out for, what to do
- Motivation: priorities, and how much attention we choose to give this matter
So, let’s get some information, and then give it our attention!
More than just memory
It’s easy to focus on memory loss, but the four key disabilities directly caused by dementia (each person may not get all four), can be remembered by the mnemonic: “AAAA!”
No, somebody didn’t just murder your writer. It’s:
- Amnesia: memory loss, in one or more of its many forms
- e.g. short term memory loss, and/or inability to make new memories
- Aphasia: loss of ability to express oneself, and/or understand what is expressed
- e.g. “More people have been to Berlin than I have”
- Or even less communication-friendly, Broca’s (Expressive) Aphasia and Wernicke’s (Receptive) Aphasia
- Apraxia: loss of ability to do things, through no obvious physical disability
- e.g. staring at the bathroom mirror wondering how to brush one’s teeth
- Agnosia: loss of ability to recognize things
- e.g. prosopagnosia, also called face-blindness.
If any of those seem worryingly familiar, be aware that while yes, it could be a red flag, what’s most important is patterns of these things.
Another difference between having a momentary brainlapse and having dementia might be, for example, the difference between forgetting your keys, and forgetting what keys do or how to use one.
That said, some are neurological deficits that may show up quite unrelated to dementia, including most of those given as examples above. So if you have just one, then that’s probably worthy of note, but probably not dementia.
Writer’s anecdote: I have had prosopagnosia all my life. To give an example of what that is like and how it’s rather more than just “bad with faces”…
Recently I saw my neighbor, and I could tell something was wrong with her face, but I couldn’t put my finger on what it was. Then some moments later, I realized I had mistaken her hat for her face. It was a large beanie with a panda design on it, and that was facelike enough for me to find myself looking at the wrong face.
Subjective memory matters as much as objective
Objective memory tests are great indicators of potential cognitive decline (or improvement!), but even a subjective idea of having memory problems, that one’s memory is “not as good as it used to be”, can be an important indicator too:
Subjective memory may be marker for cognitive decline
And more recently:
If your memory feels like it’s not what it once was, it could point to a future dementia risk
If you’d like an objective test of memory and other cognitive impairments, here’s the industry’s gold standard test (it’s free):
SAGE: A Test to Detect Signs of Alzheimer’s and Dementia
(The Self-Administered Gerocognitive Exam (SAGE) is designed to detect early signs of cognitive, memory or thinking impairments)
There are things that can look like dementia that aren’t
A person with dementia may be unable to recognize their partner, but hey, this writer knows that feeling very well too. So what sets things apart?
More than we have room for today, but here’s a good overview:
What are the early signs of dementia, and how does it differ from normal aging?
Want to read more?
You might like our previous article more specifically about reducing Alzheimer’s risk:
Reducing Alzheimer’s Risk Early!
Take care!
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Knee Cracking & Popping: Should You Be Worried?
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Dr. Tom Walters (Doctor of Physical Therapy) explains about what’s going on behind our musical knees, and whether or not this synovial symphony is cause for concern.
When to worry (and when not to)
If the clicking/cracking/popping/etc does not come with pain, then it is probably being caused by the harmless movement of fluid within the joints, in this case specifically the patellofemoral joint, just behind the kneecap.
As Dr. Walters says:
❝It is extremely important that people understand that noises from the knee are usually not associated with pathology and may actually be a sign of a healthy, well-lubricated joint. let’s be careful not to make people feel bad about their knee noise as it can negatively influence how they view their body!❞
On the other hand, there is also such a thing as patellofemoral joint pain syndrome (PFPS), which is very common, and involves pain behind the kneecap, especially upon over-stressing the knee(s).
In such cases, it is good to get that checked out by a doctor/physiotherapist.
Dr. Walters advises us to gradually build up strength, and not try for too much too quickly. He also advises us to take care to strengthen our glutes in particular, so our knees have adequate support. Gentle stretching of the quadriceps and soft tissue mobilization with a foam roller, are also recommended, to reduce tension on the kneecap.
For more on these things and especially about the exercises, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might like to read:
How To Really Take Care Of Your Joints
Take care!
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The Ultimate Booster
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Winning The Biological Arms Race
The human immune system (and indeed, other immune systems, but we are all humans here, after all) is in a constant state of war with pathogens, and that war is a constant biological arms race:
- We improve our defenses and destroy the attackers; the 1% of pathogens that survived now “know” how to counter that trick.
- The pathogens wreak havoc in our systems; the n% of us that survive now have immune systems that “know” how to counter that trick.
Vaccines are a mighty tool in our favor here, because they’re the technology that stops our n% from also being a very low number.
With vaccines, we can effectively pass on established defenses onto the population at large, as this cute video explains very well and very simply in 57 seconds:
Click Here If The Embedded Video Doesn’t Load Automatically!
The problem with vaccines
The problem is that this accelerates the arms race. It’s like a chess game where we are able to respond to every move quickly (which is good for us), and/but this means passing the move over to our opponent sooner.
That problem’s hard to avoid, because the alternative has always been “let people die in much larger numbers”.
Traditional vs mRNA vaccines
A quick refresher before we continue to the big news of the day:
- Traditional vaccines use a disabled version of a pathogen to trigger an immune response that will teach the body to recognize the pathogen ready for when the full version shows up
- mRNA vaccines use a custom-made bit of genetic information to tell the body to make its own harmless fake pathogen and then respond to the harmless fake pathogen it made.
Note: this happens independently of the host’s DNA, so no, it does not change your DNA
See also: The Truth About Vaccines
Here’s a more detailed explainer (with a helpful diagram) using the COVID mRNA vaccine as an example:
Genome.gov | How does an mRNA vaccine work?
However, this still leaves us “chasing strains”, because as the pathogen (in this case, a virus) adapts, the vaccine has to be updated too, hence all the boosters.
This is a lot like a security update for your computer’s antivirus software. They’re annoying, but they do an important job.
No more “chasing strains”
The press conference soundbite on this sums it up well:
❝Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised.❞
Read in full: Vaccine breakthrough means no more chasing strains
You may be wondering: what makes this one effective against any strain?
❝What I want to emphasize about this vaccine strategy is that it is broad.
It is broadly applicable to any number of viruses, broadly effective against any variant of a virus, and safe for a broad spectrum of people. This could be the universal vaccine that we have been looking for.
Viruses may mutate in regions not targeted by traditional vaccines. However, we are targeting their whole genome with thousands of small RNAs. They cannot escape this.❞
Importantly, this means it can be applied not just to one disease, let alone just one strain of COVID. Rather, it can be used for a wide variety of viruses that have similar viral functions—COVID / SARS in general, including influenza, and even viruses such as dengue.
How it does this: the above article explains in more detail, but in few words: it targets tiny strings of the genome that are present in all strains of the virus.
Illustrative example: if you wanted to block 10almonds (please don’t), you could block our email address.
But if we were malicious (we’re not) we could be sneaky and change it, so you’d have to block the new one, and the cycle repeats.
But if you were block all emails containing the tiny string of characters “10almonds”, changing our email address would no longer penetrate your defenses.
Now imagine also blocking strings such as “One-Minute Book Review” and “Today’s almonds have been activated by” and other strings we use in every email.
Now multiply this by thousands of strings (because genomes are much larger than our little newsletter), and you see its effectiveness!
Great! How can I get this?
It’s still in the testing stages for now; this is “breaking news” science, after all.
The study itself
…is paywalled for now, sadly, but if you happen to have institutional access, here it is:
Take care!
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Vitamin D2 vs Vitamin D3: What You Would Benefit From Knowing
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It’s Q&A Day at 10almonds!
Have a question or a request? We love to hear from you!
In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!
As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!
So, no question/request too big or small 😎
❝Hi, is there any important difference between vitamin d2 and vitamin d3? Is one better than the other?❞
There is indeed! And one is better than the other!
Where they come from
You’ll find a lot of sources that will tell you “Vitamin D2 is from plants, D3 is from animals”, and in fact only the second half of that is true.
In nature, there are no plants that are known to produce vitamin D.
Vitamin D2, however, is produced by many fungi, as well as algae, neither of which are part of the Kingdom Plantae.
Vitamin D3, meanwhile, is produced by many animals (including humans).
When “the sun” is sometimes considered a source of vitamin D, that’s true only insofar as the sun is also a source of tomatoes, for example, which required the sun to grow. While we humans (and other animals) cannot photosynthesize in general, producing vitamin D is something we can do if exposed to UV light (such as from the sun).
However, of course exposure to UV light (such as from the sun) comes with other problems, so… Should we get sun exposure or not?
We weighed up the balance of evidence, here: The Sun Exposure Dilemma
If, like this writer, you are a mostly crepuscular being who avoids the sun, we have good news: mushrooms can do the sunbathing for us!
❝Exposing mushrooms to UV (from sunlight or in a laboratory) increases the amount of vitamin D in mushrooms by nearly eightfold. Putting five store-bought button mushrooms in the sun, or just one portobello mushroom, produces 24 µg of vitamin D, which translates to nearly 1000 international units, providing the amount of vitamin D one needs in an entire day, and the equivalent found in most vitamin D supplements.
If you’re wondering if the vitamin D from mushrooms actually makes it into your bloodstream, it does. A recent meta-analysis of randomized controlled trials showed that tanned (UV-exposed) mushrooms may be effective in increasing active vitamin D levels in adults with low levels of vitamin D, and studies (randomised controlled trials) have shown that it may be just as effective as supplements at increasing vitamin D levels in the blood (here, and here).
Some research is very positive, saying that putting your mushrooms in direct sunlight for 10–15 minutes may provide you with 100% of your daily vitamin D needs, and the vitamin D content in sunlight-exposed mushrooms may be retained with refrigeration for up to 8 days.
The production of vitamin D may be increased by a further 30% by placing them in the sun with the underside, or gills, facing up, or by 60% if you slice them.❞
Read all about it: Tan your mushrooms, not your skin
Which is better?
In few words: D3 is better.
They both do the exact same job, but with D3, you simply get more bang-for-buck:
❝The WMD in change in total 25(OH)D based on 12 daily dosed vitamin D2-vitamin D3 comparisons, analyzed using liquid chromatography-tandem mass spectrometry, was 10.39 nmol/L (40%) lower for the vitamin D2 group compared with the vitamin D3 group.
Vitamin D3 leads to a greater increase of 25(OH)D than vitamin D2, even if limited to daily dose studies, but vitamin D2 and vitamin D3 had similar positive impacts on their corresponding 25(OH)D hydroxylated forms.❞
Note: “WMD” here means “weighted mean difference”, not “weapons of mass destruction”
About that “and importance of BMI”, by the way: in persons with a BMI >25, there was no longer a difference between the two forms. Literally, no difference at all; the difference was reduced to 0%.
Another study found similarly, but with different numbers (finding a greater difference), and without recording BMI as a factor:
❝D3 is approximately 87% more potent in raising and maintaining serum 25(OH)D concentrations and produces 2- to 3-fold greater storage of vitamin D than does equimolar D2.❞
See the paper: Vitamin D3 Is More Potent Than Vitamin D2 in Humans
“Well that sucks, because I’m vegan”
Fear not, you can get vegan D3 too.
Much like “you can’t get vegan B12” (but you can; it’s made by yeast), there are vegan D3 supplements, made by lichen.
The trouble with lichen, when it comes to classifying it, it that it’s actually a hybrid colony of many small, strange things (beyond the scope of this article, but they are fascinating, so this writer is holding herself back by the scruff of the neck from explaining in detail), some of which are technically part of Kingdom Animalia, but it is hard to find even the most ardent vegan who will object to consuming bacteria, for example.
Want to try some?
We don’t sell it, but here for your convenience is an example product on Amazon 😎
But watch out with the doses, if supplementing vitamin D in either form, because…
Vit D + Calcium: Too Much Of A Good Thing? ← this also talks about safe and effective doses, and what goes wrong if you take too much
Take care!
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The Top Micronutrient Deficiency In High Blood Pressure
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High blood pressure is often considered a matter of too much sodium, but there’s another micronutrient that’s critical, and a lot of people have too little of it:
The Other Special K
Potassium helps regulate blood pressure by doing the opposite of what sodium does: high sodium intake increases blood volume and pressure by retaining fluid, while potassium promotes sodium excretion through urine, reducing fluid retention and lowering blood pressure.
Clinical studies (which you can find beneath the video, if you click through to YouTube) have shown that increasing potassium intake can reduce systolic blood pressure by an average of 3.49 units, with even greater reductions (up to 7 units) at higher potassium intakes of 3,500–4,700 mg/day.
Potassium-rich foods include most fruit*, leafy greens, broccoli, lentils, and beans.
*because of some popular mentions in TV shows, people get hung up on bananas being a good source of potassium. Which they are, but they’re not even in the top 10 of fruits for potassium. Here’s a non-exhaustive list of fruits that have more potassium than bananas, portion for portion:
- Honeydew melon
- Papaya
- Mango
- Prunes
- Figs
- Dates
- Nectarine
- Cantaloupe melon
- Kiwi
- Orange
These foods also provide fiber, which aids in weight management and further lowers risks for cardiovascular disease. Increasing fiber intake by just 14g a day has been shown not only to reduce calorie consumption and promote weight loss, but also (more importantly) lower blood pressure, cholesterol, and overall health risks.
For more on all of this, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like to read:
What Matters Most For Your Heart? Eat More (Of This) For Lower Blood Pressure ← this is about fiber; while potassium is the most common micronutrient deficiency in people with high blood pressure, fiber is the most common macronutrient deficiency, and arguably the most critical in this regard.
Take care!
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Hitting the beach? Here are some dangers to watch out for – plus 10 essentials for your first aid kit
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Summer is here and for many that means going to the beach. You grab your swimmers, beach towel and sunscreen then maybe check the weather forecast. Did you think to grab a first aid kit?
The vast majority of trips to the beach will be uneventful. However, if trouble strikes, being prepared can make a huge difference to you, a loved one or a stranger.
So, what exactly should you be prepared for?
FTiare/Shutterstock Knowing the dangers
The first step in being prepared for the beach is to learn about where you are going and associated levels of risk.
In Broome, you are more likely to be bitten by a dog at the beach than stung by an Irukandji jellyfish.
In Byron Bay, you are more likely to come across a brown snake than a shark.
In the summer of 2023–24, Surf Life Saving Australia reported more than 14 million Australian adults visited beaches. Surf lifesavers, lifeguards and lifesaving services performed 49,331 first aid treatments across 117 local government areas around Australia. Surveys of beach goers found perceptions of common beach hazards include rips, tropical stingers, sun exposure, crocodiles, sharks, rocky platforms and waves.
Sun and heat exposure are likely the most common beach hazard. The Cancer Council has reported that almost 1.5 million Australians surveyed during summer had experienced sunburn during the previous week. Without adequate fluid intake, heat stroke can also occur.
Lacerations and abrasions are a further common hazard. While surfboards, rocks, shells and litter might seem more dangerous, the humble beach umbrella has been implicated in thousands of injuries.
Sprains and fractures are also associated with beach activities. A 2022 study linked data from hospital, ambulance and Surf Life Saving cases on the Sunshine Coast over six years and found 79 of 574 (13.8%) cervical spine injuries occurred at the beach. Surfing, smaller wave heights and shallow water diving were the main risks.
Rips and rough waves present a higher risk at areas of unpatrolled beach, including away from surf lifesaving flags. Out of 150 coastal drowning deaths around Australia in 2023–24, nearly half were during summer. Of those deaths:
- 56% occurred at the beach
- 31% were rip-related
- 86% were male, and
- 100% occurred away from patrolled areas.
People who had lived in Australia for less than two years were more worried about the dangers, but also more likely to be caught in a rip.
Safety Beach on Victoria’s Mornington Peninsula. Still bring your first aid essentials though. Julia Kuleshova/Shutterstock Knowing your DR ABCs
So, beach accidents can vary by type, severity and impact. How you respond will depend on your level of first aid knowledge, ability and what’s in your first aid kit.
A first aid training company survey of just over 1,000 Australians indicated 80% of people agree cardiopulmonary resuscitation (CPR) is the most important skill to learn, but nearly half reported feeling intimidated by the prospect.
CPR training covers an established checklist for emergency situations. Using the acronym “DR ABC” means checking for:
- Danger
- Response
- Airway
- Breathing
- Circulation
A complete first aid course will provide a range of skills to build confidence and be accredited by the national regulator, the Australian Skills Quality Authority.
What to bring – 10 first aid essentials
Whether you buy a first aid kit or put together you own, it should include ten essential items in a watertight, sealable container:
- Band-Aids for small cuts and abrasions
- sterile gauze pads
- bandages (one small one for children, one medium crepe to hold on a dressing or support strains or sprains, and one large compression bandage for a limb)
- large fabric for sling
- a tourniquet bandage or belt to restrict blood flow
- non-latex disposable gloves
- scissors and tweezers
- medical tape
- thermal or foil blanket
- CPR shield or breathing mask.
Before you leave for the beach, check the expiry dates of any sunscreen, solutions or potions you choose to add.
If you’re further from help
If you are travelling to a remote or unpatrolled beach, your kit should also contain:
- sterile saline solution to flush wounds or rinse eyes
- hydrogel or sunburn gel
- an instant cool pack
- paracetamol and antihistamine medication
- insect repellent.
Make sure you carry any “as-required” medications, such as a Ventolin puffer for asthma or an EpiPen for severe allergy.
Vinegar is no longer recommended for most jellyfish stings, including Blue Bottles. Hot water is advised instead.
In remote areas, also look out for Emergency Response Beacons. Located in high-risk spots, these allow bystanders to instantly activate the surf emergency response system.
If you have your mobile phone or a smart watch with GPS function, make sure it is charged and switched on and that you know how to use it to make emergency calls.
First aid kits suitable for the beach range in price from $35 to over $120. Buy these from certified first aid organisations such as Surf Lifesaving Australia, Australian Red Cross, St John Ambulance or Royal Life Saving. Kits that come with a waterproof sealable bag are recommended.
Be prepared this summer for your trip to the beach and pack your first aid kit. Take care and have fun in the sun.
Andrew Woods, Lecturer, Nursing, Faculty of Health, Southern Cross University and Willa Maguire, Associate Lecturer in Nursing, Southern Cross University
This article is republished from The Conversation under a Creative Commons license. Read the original article.
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Capsaicin For Weight Loss And Against Inflammation
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Capsaicin’s Hot Benefits
Capsaicin, the compound in hot peppers that makes them spicy, is a chemical irritant and a neurotoxin. However, humans being humans, we decided to eat them for fun.
In contrast to many other ways in which humans recreationally enjoy things that are objectively poisonous, consuming capsaicin (in moderation) is considered to have health benefits, such as aiding weight loss (by boosting metabolism) and reducing inflammation.
Let’s see what the science says…
First: is it safe?
Capsaicin is classified as “Generally Recognized As Safe”. That said, the same mechanism that causes them to boost metabolism, does increase blood pressure:
Mechanisms underlying the hypertensive response induced by capsaicin
If you are in good cardiovascular health, this increase should be slight and not pose any threat, unless for example you enter a chili-eating contest when not acclimated to such:
Capsaicin and arterial hypertensive crisis
As ever, if unsure, do check with your doctor first, especially if you are taking any blood pressure medications, or otherwise have known blood pressure issues.
Does it really boost metabolism?
It certainly does; it works by increasing oxygen consumption and raising body temperature, both of which mean more calories will be burned for the same amount of work:
Dietary capsaicin and its anti-obesity potency: from mechanism to clinical implications
This means, of course, that chili peppers enjoy the status of being functionally a “negative calorie” food, and a top-tier one at that:
Chili pepper as a body weight-loss food
Here’s a good quality study that showed a statistically significant* fat loss improvement over placebo:
*To put it in numbers, the benefit was:
- 5.91 percentage points lower body fat percentage than placebo
- 6.68 percentage points greater change in body fat mass than placebo
See also: Difference between percentages and percentage points
For those who prefer big reviews than single studies, we’ve got you covered:
Does it really reduce inflammation?
Counterintuitive as it may seem, yes. By means of reducing oxidative stress. Given that things that reduce oxidative stress tend to reduce inflammation, and in turn tend to reduce assorted disease risks (from diabetes to cancer to Alzheimer’s), this probably has more knock-on benefits too, but we don’t have room to explore all of those today.
Fresh peppers are best for this, but dried peppers (such as when purchased as a ground spice in the supermarket, or when purchased as a capsule-based supplement) still have a very respectable anti-inflammatory effect:
- Capsaicinoids, Polyphenols and Antioxidant Activities of Capsicum annuum: Comparative Study of the Effect of Ripening Stage and Cooking Methods
- A Review on the Effect of Drying on Antioxidant Potential of Fruits and Vegetables
How much should we take?
It’s recommended to start at a low dose and gradually increase it, but 2–6mg of capsaicin per day is the standard range used in studies.
If you’re getting this from peppers, then for example cayenne pepper (a good source of capsaicin) contains around 2.5mg of capsaicin per 1 gram of cayenne.
In the case of capsules, if for example you don’t like eating hot pepper, this will usually mean taking 2–6 capsules per day, depending on dosage.
Make sure to take it with plenty of water!
Where can we get it?
Fresh peppers or ground spice from your local grocery store is fine. Your local health food store probably sells the supplements, too.
If you’d like to buy it online, here is an example product on Amazon.
Note: options on Amazon were more limited than usual, so this product is not vegan, and probably not halal or kosher, as the capsule contains an unspecified gelatin.
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