Cure – by Dr. Jo Marchant

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The subtitle here, “a journey into the science of mind over body”, prompts an immediate question: is this book actually about science?

And yes, yes it is. It’s not about “positive energy” or “tapping into your divine essence” or anysuch. It’s about science, and scientific studies.

The author’s PhD is in genetics and medical microbiology, not metaphysics or something.

For those of us who read a lot of clinical studies about a lot of things (hi, regular researcher/writer here), we’re very used to placebo being used as a control in medical science.

“This drug performed no better than placebo” is generally considered a disappointing statement… But what if the placebo was already having a profound effect? Shouldn’t that be worthy of note too?

Dr. Marchant looks at more than just drugs, though, and also looks into the science (complete with EEGs and such) of hypnosis and virtual reality.

The writing style here is very accessible without skimping on science. This is to be expected; Dr. Marchant also has an MSc in science communication, and spent a time as senior editor of New Scientist magazine.

This isn’t a how-to book, but there are some practical takeaways too, specific things we can do to augment (or avoid sabotaging) any medications we take, for example.

Bottom line: placebo effect (and its evil twin, the nocebo effect) has a profound impact on all of us whether we want it or not, so we might as well learn about how it works and how to leverage it. This book gives a very good, hard science grounding.

Click here to check out “Cure” and get the most out of whatever you take (or do) for your health!

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  • For many who are suffering with prolonged grief, the holidays can be a time to reflect and find meaning in loss

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    The holiday season is meant to be filled with joy, connection and celebration of rituals. Many people, however, are starkly reminded of their grief this time of year and of whom – or what – they have lost.

    The added stress of the holiday season doesn’t help. Studies show that the holidays negatively affect many people’s mental health.

    While COVID-19-related stressors may have lessened, the grief from change and loss that so many endured during the pandemic persists. This can cause difficult emotions to resurface when they are least expected.

    I am a licensed therapist and trauma-sensitive yoga instructor. For the last 12 years, I’ve helped clients and families manage grief, depression, anxiety and complex trauma. This includes many health care workers and first responders who have recounted endless stories to me about how the pandemic increased burnout and affected their mental health and quality of life.

    I developed an online program that research shows has improved their well-being. And I’ve observed firsthand how much grief and sadness can intensify during the holidays.

    Post-pandemic holidays and prolonged grief

    During the pandemic, family dynamics, close relationships and social connections were strained, mental health problems increased or worsened, and most people’s holiday traditions and routines were upended.

    Those who lost a loved one during the pandemic may not have been able to practice rituals such as holding a memorial service, further delaying the grieving process. As a result, holiday traditions may feel more painful now for some. Time off from school or work can also trigger more intense feelings of grief and contribute to feelings of loneliness, isolation or depression.

    Sometimes feelings of grief are so persistent and severe that they interfere with daily life. For the past several decades, researchers and clinicians have been grappling with how to clearly define and treat complicated grief that does not abate over time.

    In March 2022, a new entry to describe complicated grief was added to the Diagnostic and Statistical Manual of Mental Disorders, or DSM, which classifies a spectrum of mental health disorders and problems to better understand people’s symptoms and experiences in order to treat them.

    This newly defined condition is called prolonged grief disorder. About 10% of bereaved adults are at risk, and those rates appear to have increased in the aftermath of the pandemic.

    People with prolonged grief disorder experience intense emotions, longing for the deceased, or troublesome preoccupation with memories of their loved one. Some also find it difficult to reengage socially and may feel emotionally numb. They commonly avoid reminders of their loved one and may experience a loss of identity and feel bleak about their future. These symptoms persist nearly every day for at least a month. Prolonged grief disorder can be diagnosed at least one year after a significant loss for adults and at least six months after a loss for children.

    I am no stranger to complicated grief: A close friend of mine died by suicide when I was in college, and I was one of the last people he spoke to before he ended his life. This upended my sense of predictability and control in my life and left me untangling the many existential themes that suicide loss survivors often face.

    How grieving alters brain chemistry

    Research suggests that grief not only has negative consequences for a person’s physical health, but for brain chemistry too.

    The feeling of grief and intense yearning may disrupt the neural reward systems in the brain. When bereaved individuals seek connection to their lost loved one, they are craving the chemical reward they felt before their loss when they connected with that person. These reward-seeking behaviors tend to operate on a feedback loop, functioning similar to substance addiction, and could be why some people get stuck in the despair of their grief.

    One study showed an increased activation of the amygdala when showing death-related images to people who are dealing with complicated grief, compared to adults who are not grieving a loss. The amygdala, which initiates our fight or flight response for survival, is also associated with managing distress when separated from a loved one. These changes in the brain might explain the great impact prolonged grief has on someone’s life and their ability to function.

    Recognizing prolonged grief disorder

    Experts have developed scales to help measure symptoms of prolonged grief disorder. If you identify with some of these signs for at least one year, it may be time to reach out to a mental health professional.

    Grief is not linear and doesn’t follow a timeline. It is a dynamic, evolving process that is different for everyone. There is no wrong way to grieve, so be compassionate to yourself and don’t make judgments on what you should or shouldn’t be doing.

    Increasing your social supports and engaging in meaningful activities are important first steps. It is critical to address any preexisting or co-occurring mental health concerns such as anxiety, depression or post-traumatic stress.

    It can be easy to confuse grief with depression, as some symptoms do overlap, but there are critical differences.

    If you are experiencing symptoms of depression for longer than a few weeks and it is affecting your everyday life, work and relationships, it may be time to talk with your primary care doctor or therapist.

    A sixth stage of grief

    I have found that naming the stage of grief that someone is experiencing helps diminish the power it might have over them, allowing them to mourn their loss.

    For decades, most clinicians and researchers have recognized five stages of grief: denial/shock, anger, depression, bargaining and acceptance.

    But “accepting” your grief doesn’t sit well for many. That is why a sixth stage of grief, called “finding meaning,” adds another perspective. Honoring a loss by reflecting on its meaning and the weight of its impact can help people discover ways to move forward. Recognizing how one’s life and identity are different while making space for your grief during the holidays might be one way to soften the despair.

    When my friend died by suicide, I found a deeper appreciation for what he brought into my life, soaking up the moments he would have enjoyed, in honor of him. After many years, I was able to find meaning by spreading mental health awareness. I spoke as an expert presenter for suicide prevention organizations, wrote about suicide loss and became certified to teach my local community how to respond to someone experiencing signs of mental health distress or crisis through Mental Health First Aid courses. Finding meaning is different for everyone, though.

    Sometimes, adding a routine or holiday tradition can ease the pain and allow a new version of life, while still remembering your loved one. Take out that old recipe or visit your favorite restaurant you enjoyed together. You can choose to stay open to what life has to offer, while grieving and honoring your loss. This may offer new meaning to what – and who – is around you.

    If you need emotional support or are in a mental health crisis, dial 988 or chat online with a crisis counselor.The Conversation

    Mandy Doria, Assistant Professor of Psychiatry, University of Colorado Anschutz Medical Campus

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Managing Major Chronic Diseases – by Alexis Dupree

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    Our author, Alexis Dupree, is herself in her 70s, and writing with more than three decades of experience of surviving multiple chronic diseases (in her case, Multiple Sclerosis, and then a dozen comorbidities that came with such).

    She is not a doctor or a scientist, but for more than 30 years she’s been actively working to accumulate knowledge not just on her own conditions, but on the whole medical system, and what it means to be a “forever patient” without giving up hope.

    She talks lived-experience “life management” strategies for living with chronic disease, and she talks—again from lived experience—about navigating the complexities of medical care; not on a legalistic “State regulations say…” level, because that kind of thing changes by the minute, but on a human level.

    Perhaps most practically: how to advocate strongly for yourself while still treating medical professionals with the respect and frankly compassion that they deserve while doing their best in turn.

    But also: how to change your attitude to that of a survivor, and yet also redefine your dreams. How to make a new game plan of life—while working to make life easier for yourself. How to deal, psychologically, with the likelihood that not only will you probably not get better, but also, you will probably get worse, while still never, ever, giving up.

    After all, many things are easily treatable today that mere decades ago were death sentences, and science is progressing all the time. We just have to stay alive, and in as good a condition as we reasonably can, to benefit from those advances!

    Bottom line: if you have a chronic disease, or if a loved one does, then this is an immensely valuable book to read.

    Click here to check out Managing Major Chronic Diseases, and make life easier!

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  • Oscar contender Poor Things is a film about disability. Why won’t more people say so?

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    Readers are advised this article includes an offensive and outdated disability term in a quote from the film.

    Poor Things is a spectacular film that has garnered critical praise, scooped up awards and has 11 Oscar nominations. That might be the problem. Audiences become absorbed in another world, so much so our usual frames of reference disappear.

    There has been much discussion about the film’s feminist potential (or betrayal). What’s not being talked about in mainstream reviews is disability. This seems strange when two of the film’s main characters are disabled.

    Set in a fantasy version of Victorian London, unorthodox Dr Godwin Baxter (William Dafoe) finds the just-dead body of a heavily pregnant woman in the Thames River. In keeping with his menagerie of hybrid animals, Godwin removes the unborn baby’s brain and puts it into the skull of its mother, who becomes Bella Baxter (Emma Stone).

    Is Bella really disabled?

    Stone has been praised for her ability to embody a small child who rapidly matures into a hypersexual person – one who has not had time to absorb the restrictive rules of gender or patriarchy.

    But we also see a woman using her behaviour to express herself because she has complex communication barriers. We see a woman who is highly sensitive and responsive to the sensory world around her. A woman moving through and seeing the world differently – just like the fish-eye lens used in many scenes.

    Women like this exist and they have historically been confined, studied and monitored like Bella. When medical student Max McCandless (Ramy Youssef) first meets Bella, he offensively exclaims “what a very pretty retard!” before being told the truth and promptly declared her future husband.

    Even if Bella is not coded as disabled through her movements, speech and behaviour, her onscreen creator and guardian is. Godwin Baxter has facial differences and other impairments which require assistive technology.

    So ignoring disability as a theme of the film seems determined and overt. The absurd humour for which the film is being lauded is often at Bella’s “primitive”, “monstrous” or “damaged” actions: words which aren’t usually used to describe children, but have been used to describe disabled people throughout history.

    In reviews, Bella’s walk and speech are compared to characters like the Scarecrow in The Wizard of Oz, rather than a disabled woman. So why the resistance?

    Freak shows and displays

    Disability studies scholar Rosemarie Gardland-Thomson writes “the history of disabled people in the Western world is in part the history of being on display”.

    In the 19th century, when Poor Things is set, “freak shows” featuring disabled people, Indigenous people and others with bodily differences were extremely popular.

    Doctors used freak shows to find specimens – like Joseph Merrick (also known as the Elephant Man and later depicted on screen) who was used for entertainment before he was exhibited in lecture halls. In the mid-1800s, as medicine became a profession, observing the disabled body shifted from a public spectacle to a private medical gaze that labelled disability as “sick” and pathologised it.

    Poor Things doesn’t just circle around these discourses of disability. Bella’s body is a medical experiment, kept locked away for the private viewing of male doctors who take notes about her every move in small pads. While there is something glorious, intimate and familiar about Bella’s discovery of her own sexual pleasure, she immediately recognises it as worth recording in the third person:

    I’ve discovered something that I must share […] Bella discover happy when she want!

    The film’s narrative arc ends with Bella herself training to be a doctor but one whose more visible disabilities have disappeared.

    Framing charity and sexual abuse

    Even the film’s title is an expression often used to describe disabled people. The charity model of disability sees disabled people as needing pity and support from others. Financial poverty is briefly shown at a far-off port in the film and Bella initially becomes a sex worker in Paris for money – but her more pressing concern is sexual pleasure.

    Disabled women’s sexuality is usually seen as something that needs to be controlled. It is frequently assumed disabled women are either hypersexual or de-gendered and sexually innocent.

    In the real world disabled people experience much higher rates of abuse, including sexual assault, than others. Last year’s Royal Commission into Violence, Abuse, Neglect and Exploitation of People with Disability found women with disability are nearly twice as likely as women without disability to have been assaulted. Almost a third of women with disability have experienced sexual assault by the age of 15. Bella’s hypersexual curiosity appears to give her some layer of protection – but that portrayal denies the lived experience of many.

    Watch but don’t ignore

    Poor Things is a stunning film. But ignoring disability in the production ignores the ways in which the representation of disabled bodies play into deep and historical stereotypes about disabled people.

    These representations continue to shape lives. The Conversation

    Louisa Smith, Senior lecturer, Deakin University; Gemma Digby, Lecturer – Health & Social Development, Deakin University, and Shane Clifton, Associate Professor of Practice, School of Health Sciences and the Centre for Disability Research and Policy, University of Sydney

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Chatter – by Dr. Ethan Kross
  • Basic Baked Tofu

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    One of the main criticisms of tofu is that it is tasteless. Well, so is flour, but you’re not supposed to eat it plain, and the same goes for tofu. It’s a blank canvas that you get to decide what to do with—not to mention, it’s a canvas that’s very high in protein, and is a complete protein too, containing all essential amino acids. Anyway, here’s a starter recipe that elevates tofu from “nutrition” to “nutritious tasty snack”!

    We were going to do a fancier recipe today, but considered that it might be judicious to cover this basic element first, that can be incorporated into a larger recipe later, a bit like we have done with recipes such as our Tasty Versatile Rice, and Plant-Based Healthy Cream Cheese (amongst others).

    You will need

    • 1 block of extra-firm tofu; these are quite standardized in size; it should be about 12oz; don’t worry if it’s a little more or less.
    • 2 tbsp arrowroot powder (or potato starch if you don’t have arrowroot)
    • 1½ tbsp extra virgin olive oil
    • 1 tbsp nutritional yeast
    • 1 tsp black pepper
    • ½ tsp MSG or 1 tsp low-sodium salt
    • Optional: ½ tsp garlic powder
    • Optional: ½ tsp ground turmeric

    Method

    (we suggest you read everything at least once before doing anything)

    1) Preheat the oven to 425ºF / 220ºC.

    2) Press the tofu for about 15 minutes (to remove excess moisture), using a tofu press if you have one. If you don’t, then here is an example product on Amazon, or alternatively, you can go with the time-honored tradition of cutting the tofu lengthways into slabs, and wrapping it in a lint-free kitchen towel or muslin cloth, and pressing it with heavy books. We don’t recommend pressing for more than about 15 minutes, as you are going to bake the tofu so you don’t want it too dry going in.

    3) Cut the tofu into cubes. Size is up to you, but half-inch cubes are very respectable.

    4) Combine the tofu cubes in a big bowl with the oil and seasonings, including the nutritional yeast but not the arrowroot powder or potato starch yet. You will need to toss them gently (very gently; they are fragile!) to combine.

    5) Add the arrowroot powder or potato starch, and again toss gently to combine. We do this last, because it would stop the other things from sticking properly if we did it earlier.

    6) Arrange the tofu on a baking tray lined with baking paper, in a single layer so that the cubes don’t touch. Bake for 15 minutes, turn them over, and bake for a further 15 minutes on the other side. They should now be golden and crisp, but if they’re not, just give them a little more time.

    7) Serve as a snack, or set aside for whatever else you’re going to do with them in a larger more complex recipe.

    Enjoy!

    Want to learn more?

    For those interested in some of the science of what we have going on today:

    Take care!

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  • Hormones & Health, Beyond The Obvious

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Wholesome Health

    This is Dr. Sara Gottfried, who some decades ago got her MD from Harvard and specialized as an OB/GYN at MIT. She’s since then spent the more recent part of her career educating people (mostly: women) about hormonal health, precision, functional, & integrative medicine, and the importance of lifestyle medicine in general.

    What does she want us to know?

    Beyond “bikini zone health”

    Dr. Gottfried urges us to pay attention to our whole health, in context.

    “Women’s health” is often thought of as what lies beneath a bikini, and if it’s not in those places, then we can basically treat a woman like a man.

    And that’s often not actually true—because hormones affect every living cell in our body, and as a result, while prepubescent girls and postmenopausal women (specifically, those who are not on HRT) may share a few more similarities with boys and men of similar respective ages, for most people at most ages, men and women are by default quite different metabolically—which is what counts for a lot of diseases! And note, that difference is not just “faster” or “slower””, but is often very different in manner also.

    That’s why, even in cases where incidence of disease is approximately similar in men and women when other factors are controlled for (age, lifestyle, medical history, etc), the disease course and response to treatment may vary considerable. For a strong example of this, see for example:

    • The well-known: Heart Attack: His & Hers ← most people know these differences exist, but it’s always good to brush up on what they actually are
    • The less-known: Statins: His & Hers ← most people don’t know these differences exist, and it pays to know, especially if you are a woman or care about one

    Nor are brains exempt from his…

    The female brain (kinda)

    While the notion of an anatomically different brain for men and women has long since been thrown out as unscientific phrenology, and the idea of a genetically different brain is… Well, it’s an unreliable indicator, because technically the cells will have DNA and that DNA will usually (but not always; there are other options) have XX or XY chromosomes, which will usually (but again, not always) match apparent sex (in about 1/2000 cases there’s a mismatch, which is more common than, say, red hair; sometimes people find out about a chromosomal mismatch only later in life when getting a DNA test for some unrelated reason), and in any case, even for most of us, the chromosomal differences don’t count for much outside of antenatal development (telling the default genital materials which genitals to develop into, though this too can get diverted, per many intersex possibilities, which is also a lot more common than people think) or chromosome-specific conditions like colorblindness…

    The notion of a hormonally different brain is, in contrast to all of the above, a reliable and easily verifiable thing.

    See for example:

    Alzheimer’s Sex Differences May Not Be What They Appear

    Dr. Gottfried urges us to take the above seriously!

    Because, if women get Alzheimer’s much more commonly than men, and the disease progresses much more quickly in women than men, but that’s based on postmenopausal women not on HRT, then that’s saying “Women, without women’s usual hormones, don’t do so well as men with men’s usual hormones”.

    She does, by the way, advocate for bioidentical HRT for menopausal women, unless contraindicated for some important reason that your doctor/endocrinologist knows about. See also:

    Menopausal HRT: A Tale Of Two Approaches (Bioidentical vs Animal)

    The other very relevant hormone

    …that Dr. Gottfried wants us to pay attention to is insulin.

    Or rather, its scrubbing enzyme, the prosaically-named “insulin-degrading enzyme”, but it doesn’t only scrub insulin. It also scrubs amyloid beta—yes, the same that produces the amyloid beta plaques in the brain associated with Alzheimer’s. And, there’s only so much insulin-degrading enzyme to go around, and if it’s all busy breaking down excess insulin, there’s not enough left to do the other job too, and thus can’t break down amyloid beta.

    In other words: to fight neurodegeneration, keep your blood sugars healthy.

    This may actually work by multiple mechanisms besides the amyloid hypothesis, by the way:

    The Surprising Link Between Type 2 Diabetes & Alzheimer’s

    Want more from Dr. Gottfried?

    You might like this interview with Dr. Gottfried by Dr. Benson at the IMCJ:

    Integrative Medicine: A Clinician’s Journal | Conversations with Sara Gottfried, MD

    …in which she discusses some of the things we talked about today, and also about her shift from a pharmaceutical-heavy approach to a predominantly lifestyle medicine approach.

    Enjoy!

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  • Practical Optimism – by Dr. Sue Varma

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    We’ve written before about how to get your brain onto a more positive track (without toxic positivity), but there’s a lot more to be said than we can fit into an article, so here’s a whole book packed full with usable advice.

    The subtitle claims “the art, science, and practice of…”, but mostly it’s the science of. If there’s art to be found here, then this reviewer missed it, and as for the practice of, well, that’s down to the reader, of course.

    However, it is easy to use the contents of this book to translate science into practice without difficulty.

    If you’re a fan of acronyms, initialisms, and other mnemonics (such as the rhyming “Name, Claim, Tame, and Reframe”), then you’ll love this book as they come thick and fast throughout, and they contribute to the overall ease of application of the ideas within.

    The writing style is conversational but with enough clinical content that one never forgets who is speaking—not in the egotistical way that some authors do, but rather, just, she has a lot of professional experience to share and it shows.

    Bottom line: if you’d like to be more optimistic without delving into the delusional, this book can really help a lot with that (in measurable ways, no less!).

    Click here to check out Practical Optimism, and brighten up your life!

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