Are Brain Chips Safe?
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Ready For Cyborgization?
In yesterday’s newsletter, we asked you for your views on Brain-Computer Interfaces (BCIs), such as the Utah Array and Neuralink’s chips on/in brains that allow direct communication between brains and computers, so that (for example) a paralysed person can use a device to communicate, or manipulate a prosthetic limb or two.
We didn’t get as many votes as usual; it’s possible that yesterday’s newsletter ended up in a lot of spam filters due to repeated use of a word in “extra ______ olive oil” in its main feature!
However, of the answers we did get…
- About 54% said “It’s bad enough that our phones spy on us, without BCI monitoring our thoughts as well!”
- About 23% said “Sounds great in principle, but I don’t think we’re there yet safetywise”
- About 19% said “Sign me up for technological telepathy! I am ready for assimilation”
- One (1) person said “Electrode outside the skull are good; chips on the brain are bad”
But what does the science say?
We’re not there yet safetywise: True or False?
True, in our opinion, when it comes to the latest implants, anyway. While it’s very difficult to prove a negative (it could be that everything goes perfectly in human trials), “extraordinary claims require extraordinary evidence”, and so far this seems to be lacking.
The stage before human trials is usually animal trials, starting with small creatures and working up to non-human primates if appropriate, before finally humans.
- Good news: the latest hot-topic BCI device (Neuralink) was tested on animals!
- Bad news: to say it did not go well would be an understatement
The Gruesome Story of How Neuralink’s Monkeys Actually Died
The above is a Wired article, and we tend to go for more objective sources, however we chose this one because it links to very many objective sources, including an open letter from the Physicians’ Committee for Responsible Medicine, which basically confirms everything in the Wired article. There are lots of links to primary (medical and legal) sources, too.
Electrodes outside the skull are good; chips on/in the brain are bad: True or False?
True or False depending on how they’re done. The Utah Array (an older BCI implant, now 20 years old, though it’s been updated many times since) has had a good safety record, after being used by a few dozen people with paralysis to control devices:
How the Utah Array is advancing BCI science
The Utah Array works on the same general principle as Neuralink, but the mechanics of its implementation are very different:
- The Utah Array involves a tiny bundle of microelectrodes (held together by a rigid structure that looks a bit like a nanoscale hairbrush) put in place by a brain surgeon, and that’s that.
- The Neuralink has a dynamic web of electrodes, implanted by a little robot that acts like a tiny sewing machine to implant many polymer threads, each containing its own a bunch of electrodes.
In theory, the latter is much more advanced. In practice, so far, the former has a much better safety record.
I am right to be a little worried about giving companies access to my brain: True or False?
True or False, depending on the nature of your concern.
For privacy: current BCI devices have quite simple switches operated consciously by the user. So while technically any such device that then runs its data through Bluetooth or WiFi could be hacked, this risk is no greater than using a wireless mouse and/or keyboard, because it has access to about the same amount of information.
For safety: yes, probably there is cause to be worried. Likely the first waves of commercial users of any given BCI device will be severely disabled people who are more likely to waive their rights in the hope of a life-changing assistance device, and likely some of those will suffer if things go wrong.
Which on the one hand, is their gamble to make. And on the other hand, makes rushing to human trials, for companies that do that, a little more predatory.
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“Skinny Fat” Explained (& How To Fix It)
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“Skinny fat” is a term you may have seen floating around social media. It describes people who have a low body weight but a high body fat percentage, often resulting in flabby appearance despite being within a weight range considered healthy. Many try dieting and exercising, only to find that neither work.
This video explains what’s going wrong, and how to fix it:
Diet & exercise won’t work if it’s not right
This problem occurs because common weight-loss approaches, such as restrictive dieting and excessive cardio, fail to improve body composition:
- Restrictive dieting reduces both fat and lean mass, keeping the body fat percentage unchanged
- Cardio burns some calories but the underlying metabolic issue hasn’t meaningfully changed, so any loss will be temporary (and most of any immediate loss will be water weight, anyway)
The key to overcoming skinny fat is resistance training. Lifting weights or doing bodyweight exercises helps build muscle, which not only lowers body fat percentage (by simple mathematics; add more muscle and the percentages of other things must go down even if the total amount is the same) and improves overall definition, which is something most people consider nice. However, the real value here is that it actually addresses the underlying metabolic issue—because muscle costs calories to maintain, one’s basal metabolic rate will now be faster, even when you’re sleeping.
This then becomes… Not quite a self-sustaining system, because you do have to still eat well and continue to do resistance training, but your body will be doing most of the work for you, and you’ll find it’s a lot easier to maintain a healthy body composition than to get one in the first place, for exactly the metabolic reason we described.
For more on all of this, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like:
Visceral Belly Fat & How To Lose It ← this is a different, but adjacent issue (and very important for avoiding metabolic disease risks)
Take care!
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Will there soon be a cure for HIV?
10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.
Human immunodeficiency virus, or HIV, is a chronic health condition that can be fatal without treatment. People with HIV can live healthy lives by taking antiretroviral therapy (ART), but this medication must be taken daily in order to work, and treatment can be costly. Fortunately, researchers believe a cure is possible.
In July, a seventh person was reportedly cured of HIV following a 2015 stem cell transplant for acute myeloid leukemia. The patient stopped taking ART in 2018 and has remained in remission from HIV.
Read on to learn more about HIV, the promise of stem cell transplants, and what other potential cures are on the horizon.
What is HIV?
HIV infects and destroys the immune system’s cells, making people more susceptible to infections. If left untreated, HIV will severely impair the immune system and progress to acquired immunodeficiency syndrome (AIDS). People living with untreated AIDS typically die within three years.
People with HIV can take ART to help their immune systems recover and to reduce their viral load to an undetectable level, which slows the progression of the disease and prevents them passing the virus to others.
How can stem cell transplants cure HIV?
Several people have been cured of HIV after receiving stem cell transplants to treat leukemia or lymphoma. Stem cells are produced by the spongy tissue located in the center of some bones, and they can turn into new blood cells.
A mutation on the CCR5 gene prevents HIV from infecting new cells and creates resistance to the virus, which is why some HIV-positive people have received stem cells from donors carrying this mutation. (One person was reportedly cured of HIV after receiving stem cells without the CCR5 mutation, but further research is needed to understand how this occurred.)
Despite this promising news, experts warn that stem cell transplants can be fatal, so it’s unlikely this treatment will be available to treat people with HIV unless a stem cell transplant is needed to treat cancer. People with HIV are at an increased risk for blood cancers, such as Hodgkin lymphoma and non-Hodgkin lymphoma, which stem cell transplants can treat.
Additionally, finding compatible donors with the CCR5 mutation who share genetic heritage with patients of color can be challenging, as donors with the mutation are typically white.
What are other potential cures for HIV?
In some rare cases, people who started ART shortly after infection and later stopped treatment have maintained undetectable levels of HIV in their bodies. There have also been some people whose bodies have been able to maintain low viral loads without any ART at all.
Researchers are studying these cases in their search for a cure.
Other treatment options researchers are exploring include:
- Gene therapy: In addition to stem cell transplants, gene therapy for HIV involves removing genes from HIV particles in patients’ bodies to prevent the virus from infecting other cells.
- Immunotherapy: This treatment is typically used in cancer patients to teach their immune systems how to fight off cancer. Research has shown that giving some HIV patients antibodies that target the virus helps them reach undetectable levels of HIV without ART.
- mRNA technology: mRNA, a type of genetic material that helps produce proteins, has been used in vaccines to teach cells how to fight off viruses. Researchers are seeking a way to send mRNA to immune system cells that contain HIV.
When will there be a cure for HIV?
The United Nations and several countries have pledged to end HIV and AIDS by 2030, and a 2023 UNAIDS report affirmed that reaching this goal is possible. However, strategies to meet this goal include HIV prevention and improving access to existing treatment alongside the search for a cure, so we still don’t know when a cure might be available.
How can I find out if I have HIV?
You can get tested for HIV from your primary care provider or at your local health center. You can also purchase an at-home HIV test from a drugstore or online. If your at-home test result is positive, follow up with your health care provider to confirm the diagnosis and get treatment.
For more information, talk to your health care provider.
This article first appeared on Public Good News and is republished here under a Creative Commons license.
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The Toe-Tapping Tip For Better Balance
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Balance is critical for health especially in older age, since it’s amazing how much else can go dramatically and suddenly wrong after a fall. So, here’s an exercise to give great balance and stability:
How to do it
You will need:
- Something to hold onto, such as a countertop
- A target on the floor, such as a mark or a coin
The steps:
- Lift one leg up, bring your foot forward, and tap the object in front of you.
- Then, bring that foot back to where it started.
- Next, switch to the other leg and tap.
- Alternate between your right and left legs, shifting back and forth.
- Your goal is to do this for 10 repetitions on each leg without holding on.
How it works:
Whenever you tap, you have to lift one leg up and reach it out in front of you. Doing this requires you to stand on one leg while moving a weight (namely: your other leg), which is something many people, especially upon getting older, are hesitant to do. If you’re unable to stand on one leg, let alone move your center of gravity (per the counterbalance of the other leg) while doing so, you may end up shuffling and walking with your feet sliding across the ground—something you really want to avoid.
For more on all of this plus a visual demonstration, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like to read:
Fall Special ← this is about not falling, or, failing that, minimizing injury if you do
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6 Worst Foods That Cause Dementia
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How many do you consume?
The hit list
Dr. Li bids us avoid:
High carb, low fiber foods: consuming a diet high in carbohydrates, particularly refined carbs like cakes, white bread, pizza, and sugary syrups, can significantly harm brain health. Over time, imbalanced (i.e. not balanced with fiber) carbohydrate consumption leads to the growth of visceral fat (not the same as subcutaneous fat, which is the squishy bits just under your skin; visceral fat is further underneath, around your viscera), , which triggers systemic inflammation and oxidative stress. These processes disrupt communication between brain cells, impair memory, and increase the risk of diseases like Alzheimer’s and Parkinson’s. High carb diets can also contribute to metabolic syndrome—a cluster of conditions, including diabetes, obesity and high blood pressure—that damage blood vessels, leading to strokes and vascular dementia.
Trans fats: these are region-bound, as they’re banned in some places and not others—check your local regulations. Found in processed foods such as fried items, baked goods, packaged snacks, and margarine, trans fats are created through hydrogenation, which makes fats more stable at room temperature. These artificial fats raise bad cholesterol, lower good cholesterol, and promote atherosclerosis. This damages the brain by reducing oxygen supply, triggering chronic inflammation, and increasing the risk of Alzheimer’s and dementia.
Sodas: regular consumption of sodas, whether sugary or artificially sweetened, is harmful to brain health. A single can of soda contains around 9 teaspoons of sugar, which overwhelms metabolism, contributes to insulin resistance, and leads to inflammation. These effects damage blood vessels and brain tissue, disrupt neuron function, and increase the risk of type 2 diabetes and dementia. Furthermore, insulin resistance caused by excessive sugar intake can impair neuronal survival, activate immune responses, and exacerbate cognitive decline. As for the artificial sweeteners, the mechanism of harm depends on the sweetener (and some can also mess up insulin response, for reasons that are not entirely clear yet, but they measurably do), but even picking the healthiest artificial sweetener, training your palate to enjoy hyper-sweetened things will tend to lead to more sugar-laden food choices in other parts of one’s diet.
Processed foods: arguably a broad category that encompasses some of the above, but it’s important to consider it separately for catch-all purposes: these convenience foods, laden with artificial preservatives, colors, and sweeteners, harm brain health through chronic inflammation and usually a lack of essential nutrients. Processed foods are also a significant source of microplastics, which have been found to accumulate in the arteries, contributing to plaque build-up, atherosclerosis, and reduced blood flow to the brain. This combination of inflammation and oxidative stress from microplastics damages brain cells, paving the way for cognitive decline and dementia.
Seafood with high mercury levels: large fish such as tuna, swordfish, sharks, and tilefish accumulate high amounts of mercury, a potent neurotoxin. Fish that are larger, older, and/or higher up the food chain will have the most mercury (and other cumulative contaminants, for that matter, but we’re considering mercury here). Mercury disrupts essential brain chemicals like dopamine and serotonin, triggering oxidative stress and damaging brain cells. Chronic exposure to mercury leads to inflammation and neuroinflammation, both of which increase the risk of Alzheimer’s and dementia.
Alcohol: contrary to popular belief, any amount of alcohol is detrimental to brain health. While red wine is often promoted for its health benefits, the purported positive effects come from polyphenols, not the alcohol itself, and (for example) resveratrol from red wine cannot be delivered in meaningful doses without drinking an impossibly large quantity. Alcohol is a neurotoxin that can damage or kill brain cells, impair neuronal communication, and lead to cognitive decline. Excessive drinking results in hangover symptoms like headaches and brain fog, which are indicators of its harmful impact on the brain. Chronic alcohol consumption exacerbates neuron death, increases inflammation, and raises the risk of dementia.
As for what to eat instead?
Dr. Li recommends including foods such as:
- foods rich in omega-3s that aren’t mercury-laden fish, e.g. flaxseeds, chia seeds, walnuts, and hemp seeds, as they reduce inflammation, protect blood vessel linings, and prevent vascular dementia.
- berries, and in particular he recommends organic strawberries, which are rich in ellagic acid and anthocyanins, which improve memory, reduce depressive symptoms, and enhance cognitive function.
For more on all of these, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like to read:
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Cannellini Protein Gratin
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A healthier twist on a classic, the protein here comes not only from the cannellini beans, but also from (at the risk of alienating French readers) a béchamel sauce that is not made using the traditional method involving flour and butter, but instead, has cashew protein as a major constituent.
You will need
- 3 medium potatoes, chopped (no need to peel them; you can if you want, but many of the nutrients are there and they’re not a problem for the recipe)
- 1 can cannellini beans (also called white kidney beans)
- 1 medium onion, chopped
- 2 stalks celery, sliced
- 1 carrot, chopped
- ½ bulb garlic, minced (or more, if you like)
- 1 jalapeño, chopped
- 2 tbsp tomato paste
- 1 tbsp chia seeds
- 2 tsp black pepper, coarse ground
- Extra virgin olive oil, for frying
For the béchamel sauce:
- ½ cup milk (we recommend a neutral-tasting plant milk, such as unsweetened soy, but go with your preference)
- ⅓ cup cashews, soaked in hot water for at least 5 minutes (longer is fine) and drained
- ¼ cup nutritional yeast
- 1 tsp garlic powder
- 1 tsp dried thyme
Method
(we suggest you read everything at least once before doing anything)
Note: it will be a bonus if you can use a pan that is good both for going on the hob and in the oven, such as a deep cast iron skillet, or a Dutch oven. If you don’t have something like that though, it’s fine, just use a sauté pan or similar, and then transfer to an oven dish for the oven part—we’ll mention this again when we get to it.
1) Preheat the oven to 250℉/175℃.
2) Heat the pan, adding some oil and then the oven; fry it for about 5 minutes, stirring often.
3) Add the potatoes, celery, carrot, garlic, and jalapeño, stirring for another 2 minutes.
4) Add the tomato paste, along with 1 cup water, the chia seeds, and the black pepper, and cook for a further 15 minutes, stirring occasionally as necessary.
5) Add the cannellini beans, and cook for another 15 minutes, stirring occasionally as necessary.
6) Blend all the ingredients for the béchamel sauce, processing it until it is smooth.
7) If you are using an oven-safe pan, pour the béchamel sauce over the bean mixture (don’t stir it; the sauce should remain on top) and transfer it to the oven. Don’t use a lid.
If you’re not using an oven safe pan, first transfer the bean mixture to an oven dish, then pour the béchamel sauce over the bean mixture (don’t stir it; the sauce should remain on top) and put it in the oven. Don’t use a lid.
8) Bake for about 15 minutes, or until turning golden-brown on top.
9) Serve! It can be enjoyed on its own, or with salad and/or rice. See also, our Tasty Versatile Rice Recipe.
Enjoy!
Want to learn more?
For those interested in some of the science of what we have going on today:
- What Matters Most For Your Heart?
- The Many Health Benefits Of Garlic
- Easily Digestible Vegetarian Protein Sources
- Is Dairy Scary?
- Cashew Nuts vs Coconut – Which is Healthier?
- Black Pepper’s Impressive Anti-Cancer Arsenal (And More)
Take care!
Don’t Forget…
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Broccoli vs Cauliflower – Which is Healthier?
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Our Verdict
When comparing broccoli to cauliflower, we picked the broccoli.
Why?
This one is quite straightforward. Superficially, they’re very similar:
Both are great cruciferous vegetables with many health benefits to offer. Even for those keen to avoid oxalates, which cruciferous vegetables in general can be high in, these ones are quite low.
However, if you have IBS, you might want to avoid both, for their raffinose content that may cause problems for you.
For pretty much everyone else, unless you have a special reason why it’s not the case for you, both are a good source of abundant vitamins and minerals, and yet…
Anything cauliflower can do, broccoli can do better!
Broccoli contains more of the vitamins they both contain, and more of the minerals they both contain.
Broccoli also beats cauliflower on amino acids (except lysine), and contains a lot more lutein and zeaxanthin, carotenoids important for healthy eyes and brain.
So by all means enjoy both, but if you’re going to pick one, pick broccoli!
Want to know more?
Check out: Brain Food? The Eyes Have It!
Enjoy!
Don’t Forget…
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