The Sugar Alcohol That Reduces BMI!

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Inositol Does-It-Ol’!

First things first, a quick clarification up-front:

Myo-inositol or D-chiro-inositol?

We’re going to be talking about inositol today, which comes in numerous forms, but most importantly:

  • Myo-inositol (myo-Ins)
  • D-chiro-inositol (D-chiro-Ins)

These are both inositol, (a sugar alcohol!) and for our purposes today, the most relevant form is myo-inositol.

The studies we’ll look at today are either:

  • just about myo-inositol, or
  • about myo-inositol in the presence of d-chiro-inositol at a 40:1 ratio.

You have both in your body naturally; wherever supplementation is mentioned, it means supplementing with either:

  • extra myo-inositol (because that’s the one the body more often needs more of), or
  • both, at the 40:1 ratio that we mentioned above (because that’s one way to help balance an imbalanced ratio)

With that in mind…

Inositol against diabetes?

Inositol is known to:

  • decrease insulin resistance
  • increase insulin sensitivity
  • have an important role in cell signaling
  • have an important role in metabolism

The first two things there both mean that inositol is good against diabetes. It’s not “take this and you’re cured”, but:

  • if you’re pre-diabetic it may help you avoid type 2 diabetes
  • if you are diabetic (either type) it can help in the management of your diabetes.

It does this by allowing your body to make better use of insulin (regardless of whether that insulin is from your pancreas or from the pharmacy).

How does it do that? Research is still underway and there’s a lot we don’t know yet, but here’s one way, for example:

❝Evidence showed that inositol phosphates might enhance the browning of white adipocytes and directly improve insulin sensitivity through adipocytes❞

Read: Role of Inositols and Inositol Phosphates in Energy Metabolism

We mentioned its role in metabolism in a bullet-point above, and we didn’t just mean insulin sensitivity! There’s also…

Inositol for thyroid function?

The thyroid is one of the largest endocrine glands in the body, and it controls how quickly the body burns energy, makes proteins, and how sensitive the body should be to other hormones. So, it working correctly or not can have a big impact on everything from your mood to your weight to your energy levels.

How does inositol affect thyroid function?

  • Inositol has an important role in thyroid function and dealing with autoimmune diseases.
  • Inositol is essential to produce H2O2 (yes, really) required for the synthesis of thyroid hormones.
  • Depletion of inositol may lead to the development of some thyroid diseases, such as hypothyroidism.
  • Inositol supplementation seems to help in the management of thyroid diseases.

Read: The Role of Inositol in Thyroid Physiology and in Subclinical Hypothyroidism Management

Inositol for PCOS?

A systematic review published in the Journal of Gynecological Endocrinology noted:

  • Inositol can restore spontaneous ovarian activity (and consequently fertility) in most patients with PCOS.
  • Myo-inositol is a safe and effective treatment to improve:
    • ovarian function
    • healthy metabolism
    • healthy hormonal balance

While very comprehensive (which is why we included it here), that review’s a little old, so…

Check out this cutting edge (Jan 2023) study whose title says it all:

Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials

Inositol for fertility?

Just last year, Mendoza et al published that inositol supplementation, together with antioxidants, vitamins, and minerals, could be an optimal strategy to improve female fertility.

This built from Gambiole and Forte’s work, which laid out how inositol is a safe compound for many issues related to fertility and pregnancy. In particular, several clinical trials demonstrated that:

  • inositol can have therapeutic effects in infertile women
  • inositol can also be useful as a preventive treatment during pregnancy
  • inositol could prevent the onset of neural tube defects
  • inositol also reduces the occurrence of gestational diabetes

Due to the safety and efficiency of inositol, it can take the place of many drugs that are contraindicated in pregnancy. Basically: take this, and you’ll need fewer other drugs. Always a win!

Read: Myo-Inositol as a Key Supporter of Fertility and Physiological Gestation

Inositol For Weight Loss

We promised you “this alcohol sugar can reduce your BMI”, and we weren’t making it up!

Zarezadeh et al conducited a very extensive systematic review, and found:

  • Oral inositol supplementation has positive effect on BMI reduction.
  • Inositol in the form of myo-inositol had the strongest effect on BMI reduction.
  • Participants with PCOS and/or who were overweight, experienced the most significant improvement of all.

Want some inositol?

As ever, we don’t sell it (or anything else), but for your convenience, here’s myo-inositol and d-chiro-inositol at a 40:1 ratio, available on Amazon!

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  • The Menopause Manifesto – by Dr. Jen Gunter

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  • Lyme Disease At-A-Glance

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s Q&A Day at 10almonds!

    Have a question or a request? You can always hit “reply” to any of our emails, or use the feedback widget at the bottom!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    ❝Good info as always…was wondering if you have any recommendations for fighting Lyme disease naturally along wDr advice? Dr’s aren’t real keen on alternatives so always interested. Thanks❞

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    Prevention:

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    • If you are in a high-risk area and/or engage in high-risk activities, check your body daily.
      • This is because it usually takes 36–48 hours of being attached for a tick to cause an infection
      • Obviously best if you can get a partner or close friend to help you with this, unless you have mastered some advanced pretzel positions of yoga.
    • Contrary to many folk remedies, the safest way to remove a tick is with tweezers (carefully!).
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    Cure:

    • No. Sorry. Regretfully, antibiotics are the only known effective treatment.

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    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing canned tuna to canned sardines, we picked the sardines.

    Why?

    This comparison is unfair, but practical—because both are sold next to each other in the supermarket and often used for similar things.

    It’s unfair because in a can of tuna, there is tuna meat, whereas in a can of sardines, there is sardine meat, skin, and bones.

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    To be completely unambiguous:

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    About that skin and bones…

    That’s where the real benefit for your joints lies, by the way!

    See: We Are Such Stuff As Fish Are Made Of

    Enjoy!

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    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    If you’re trying to eat more plant-based, this is a great way to enjoy a culinary experience that hits the same notes as scrambled egg, with many similar nutritional benefits too, and some of its own!

    You will need

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    • 1 tbsp nutritional yeast
    • 2 tsp chia seeds
    • 2 tsp dried thyme, or 1 tsp fresh thyme, stripped (i.e. pulled off the stalks)
    • 2 tsp turmeric
    • 2 tsp black pepper, coarse ground
    • 1 tsp red chili flakes
    • ½ tsp MSG, or 1 tsp low-sodium salt
    • Extra virgin olive oil, for frying

    Method

    (we suggest you read everything at least once before doing anything)

    1) Heat a skillet with olive oil in it; if you want a low-calorie option, you can use quite little oil here; the tofu is a lot more forgiving than egg in this regard and is almost impossible to burn unless you actively try. If you don’t want a low-calorie option, feel free to be generous with the oil if you prefer; it’ll go into the tofu and make it fattier, much like egg.

    2) Add the tofu. You can just drop it (carefully) straight in; you don’t need to press it or anything.

    3) Scramble it with a spatula, just the same as you would if it were egg.

    4) Add the rest of the ingredients, mixing them in as you continue to scramble it, until it reaches the desired consistency.

    5) Serve! Serving it on wholegrain toast is a great option—but this dish can also be enjoyed any other way you might use scrambled eggs (including for making egg-fried tofu-fried rice; just stir it into our Tasty Versatile Rice recipe!)

    Enjoy!

    Want to learn more?

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    Take care!

    Don’t Forget…

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    Learn to Age Gracefully

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    Learn to Age Gracefully

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