What Seasonal Allergies Mean For Your Heart

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Most people associate seasonal allergies with itchy eyes and stuffy noses, but the effects can go a lot deeper.

This is because allergic reactions don’t just affect the respiratory system; they trigger chronic inflammation throughout the body, and in fact:

❝Allergic disease is a systemic and inflammatory condition❞

~ Dr. Rauno Joks, whose work we will cite in a moment

The important thing to understand in terms of heart health, is that chronic* systemic inflammation can contribute to coronary artery disease, where plaque buildup in arteries (bearing in mind, arterial plaque is in large part made of dead immune cells) raises the risk of heart attacks and strokes.

*Yes, a season once or twice per year counts as “chronic”.

A large (n=603,140) study found that allergic rhinitis (hay fever) increased the odds of coronary heart disease by 25% and heart attacks by 20%. Asthma, especially during flare-ups, posed an even greater risk:

The Relationship Between Allergic Rhinitis, Asthma, and Cardiovascular Disease in the National Health Interview Surveys (NHIS)

Beyond biology

The effects aren’t just biological; allergies can limit physical activity, leading to a sedentary lifestyle that harms heart health.

In other words: if you’re not going outdoors because there’s pollen, and you’re not exercising because you’re exhausted, then the rest of your health is going to take a nose-dive (so to speak) too.

So, one more reason to take it seriously and not just dismiss it as “it’s just allergies, I’ll survive”.

Practical takeaways

Some things we can all do:

  • Monitor your risk factors; i.e. keep on top of your heart health metrics, especially blood pressure and cholesterol, as well as any known genetic predisposition to cardiovascular disease.
  • Watch out for alternative causes: symptoms like fatigue or shortness of breath may not always be allergies; they could signal asthma, reflux (for example if wheezing), or even heart disease. An allergist is a good first port-of-call, though.
  • Be cautious with medications: some decongestants / allergy meds / asthma meds can raise blood pressure and/or interfere with other medications. Your pharmacist is the best person to speak to about this; they know this kind of thing much better than doctors, as a rule. And whenever you get a new medication, it is good practice to make a habit of always reading the information leaflet that comes with it, and/or look it up on a reputable website such as Drugs.com or the the BNF, to learn about what it is, how it works, what the risks are, what its contraindications are, etc.
  • Don’t ignore warning signs: lightheadedness or chest pain could indicate a heart issue and should be addressed immediately. It’s better to be wrong and temporarily embarrassed, than wrong and permanently dead. Besides, even if it’s not a heart issue, it may be something else that would benefit from attention, so taking it seriously is always a good idea.

Want to know more?

Check out:

Take care!

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  • “The Longevity Vitamin” (That’s Not A Vitamin)

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    The Magic of Mushrooms

    “The Longevity Vitamin that’s not a vitamin” is a great tagline for what’s actually an antioxidant amino acid nutraceutical, but in this case, we’re not the ones spearheading its PR, but rather, the Journal of Nutritional Science:

    Is ergothioneine a “longevity vitamin” limited in the American diet?

    It can be found in all foods, to some extent, but usually in much tinier amounts than would be useful. The reason for this is that it’s synthesized by a variety of microbes (mostly fungi and actinobacteria), and enters the food chain via vegetables that are grown in soil that contain such (which is basically all soil, unless you were to go out of your way to sterilize it, or something really unusually happened).

    About those fungi? That includes common popular edible fungi, where it is found quite generously. An 85g (3oz) portion of (most) mushrooms contains about 5mg of ergothioneine, the consumption of which is associated with a 16% reduced all-cause mortality:

    Association of mushroom consumption with all-cause and cause-specific mortality among American adults: prospective cohort study findings from NHANES III

    However… Most Americans don’t eat that many mushrooms, and those polled averaged 1.1mg/day ergothioneine (in contrast with, for example, Italians’ 4.6mg/day average).

    Antioxidant properties

    While its antioxidant properties aren’t the most exciting quality, they are worth a mention, on account of their potency:

    The biology of ergothioneine, an antioxidant nutraceutical

    This is also part of its potential bid to get classified as a vitamin, because…

    ❝Decreased blood and/or plasma levels of ergothioneine have been observed in some diseases, suggesting that a deficiency could be relevant to the disease onset or progression❞

    ~ Dr. Barry Halliwell et al.

    Source: Ergothioneine: a diet-derived antioxidant with therapeutic potential

    Healthy aging

    Building on from the above, ergothioneine has been specifically identified as being associated with healthy aging and the prevention of cardiometabolic diseases:

    ❝An increasing body of evidence suggests ergothioneine may be an important dietary nutrient for the prevention of a variety of inflammatory and cardiometabolic diseases and ergothioneine has alternately been suggested as a vitamin, “longevity vitamin”, and nutraceutical❞

    ~ Dr. Bernadette Moore et al., citing more references every few words there

    Source: Ergothioneine: an underrecognised dietary micronutrient required for healthy ageing?

    Good for the heart = good for the brain

    As a general rule of thumb, “what’s good for the heart is good for the brain” is almost always true, and it appears to be so in this case, too:

    ❝Ergothioneine crosses the blood–brain barrier and has been reported to have beneficial effects in the brain. In this study, we discuss the cytoprotective and neuroprotective properties of ergotheioneine, which may be harnessed for combating neurodegeneration and decline during aging.❞

    ~ Dr. Bindu Paul

    Source: Ergothioneine: A Stress Vitamin with Antiaging, Vascular, and Neuroprotective Roles?

    Want to get some?

    You can just eat a portion of mushrooms per day! But if you don’t fancy that, it is available as a supplement in convenient 1/day capsule form too.

    We don’t sell it, but for your convenience, here is an example product on Amazon

    Enjoy!

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  • You Are Not Broken – by Dr. Kelly Casperson

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    Many women express “I think I’m broken down there”, and it turns out simply that neither they nor their partners had the right knowledge, that’s all. The good news is: bedroom competence is an entirely learnable skill!

    Dr. Casperson is a urologist, and over the years has expanded her work into all things pelvic, including the relevant use of both systemic and topical hormones (as in, hormones to increase overall blood serum levels of that hormone, like most HRT, and also, creams and lotions to increase levels of a given hormone in one particular place).

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  • What Most People Don’t Know About HIV

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    What To Know About HIV This World AIDS Day

    Yesterday, we asked 10almonds readers to engage in a hypothetical thought experiment with us, and putting aside for a moment any reason you might feel the scenario wouldn’t apply for you, asked:

    ❝You have unprotected sex with someone who, afterwards, conversationally mentions their HIV+ status. Do you…❞

    …and got the above-depicted, below-described, set of responses. Of those who responded…

    • Just over 60% said “rush to hospital; maybe a treatment is available”
    • Just under 20% said “ask them what meds they’re taking (and perhaps whether they’d like a snack)”
    • Just over 10% said “despair; life is over”
    • Two people said “do the most rigorous washing down there you’ve ever done in your life”

    So, what does science say about it?

    First, a quick note on terms

    • HIV is the Human Immunodeficiency Virus. It does what it says on the tin; it gives humans immunodeficiency. Like many viruses that have become epidemic in humans, it started off in animals (called SIV, because there was no “H” involved yet), which were then eaten by humans, passing the virus to us when it one day mutated to allow that.
      • It’s technically two viruses, but that’s beyond the scope of today’s article; for our purposes they are the same. HIV-1 is more virulent and infectious than HIV-2, and is the kind more commonly found in most of the world.
    • AIDS is Acquired Immunodeficiency Syndrome, and again, is what it sounds like. When a person is infected with HIV, then without treatment, they will often develop AIDS.
      • Technically AIDS itself doesn’t kill people; it just renders people near-defenseless to opportunistic infections (and immune-related diseases such as cancer), since one no longer has a properly working immune system. Common causes of death in AIDS patients include cancer, influenza, pneumonia, and tuberculosis.

    People who contract HIV will usually develop AIDS if untreated. Untreated life expectancy is about 11 years.

    HIV/AIDS are only a problem for gay people: True or False?

    False, unequivocally. Anyone can get HIV and develop AIDS.

    The reason it’s more associated with gay men, aside from homophobia, is that since penetrative sex is more likely to pass it on, then if we go with the statistically most likely arrangements here:

    • If a man penetrates a woman and passes on HIV, that woman will probably not go on to penetrate someone else
    • If a man penetrates a man and passes on HIV, that man could go on to penetrate someone else—and so on
    • This means that without any difference in safety practices or promiscuity, it’s going to spread more between men on average, by simple mathematics.
    • This is why “men who have sex with men” is the generally-designated higher-risk category.

    There is medication to cure HIV/AIDS: True or False?

    False so far (though there have been individual case studies of gene treatments that may have cured people—time will tell).

    But! There are medications that can prevent HIV from being a life-threatening problem:

    • PrEP (Pre-Exposure Prophylaxis) is a medication that one can take in advance of potential exposure to HIV, to guard against it.
      • This is a common choice for people aren’t sure about their partners’ statuses, or people working in risky environments.
    • PEP (Post-Exposure Prophylaxis) is a medication that one can take after potential exposure to HIV, to “nip it in the bud”.
      • Those of you who were rushing to hospital in our poll, this is what you’re rushing there for.
    • ARVs (Anti-RetroVirals) are a class of medications (there are different options; we don’t have room to distinguish them) that reduce an HIV+ person’s viral load to undetectable levels.
      • Those of you who were asking what meds your partner was taking, these will be those meds. Also, most of them are to be taken in the morning with food, so that’s what the snack was for.

    If someone is HIV+, the risk of transmission in unprotected sex is high: True or False?

    True or False, with false being the far more likely. It depends on their medications, and this is why you were asking. If someone is on ARVs and their viral load is undetectable (as is usual once someone has been on ARVs for 6 months), they cannot transmit HIV to you.

    U=U is not a fancy new emoticon, it means “undetectable = untransmittable”, which is a mathematically true statement in the case of HIV viral loads.

    See: NIH | HIV Undetectable=Untransmittable (U=U)

    If you’re thinking “still sounds risky to me”, then consider this:

    You are safer having unprotected sex with someone who is HIV+ and on ARVs with an undetectable viral load, than you are with someone you are merely assuming is HIV- (perhaps you assume it because “surely this polite blushing young virgin of a straight man won’t give me cooties” etc)

    Note that even your monogamous partner of many decades could accidentally contract HIV due to blood contamination in a hospital or an accident at work etc, so it’s good practice to also get tested after things that involve getting stabbed with needles, cut in a risky environment, etc.

    If you’re concerned about potential stigma associated with HIV testing, you can get kits online:

    CDC | How do I find an HIV self-test?

    (these are usually fingerprick blood tests, and you can either see the results yourself at home immediately, or send it in for analysis, depending on the kit)

    If I get HIV, I will get AIDS and die: True or False?

    False, assuming you get treatment promptly and keep taking it. So those of you who were at “despair; life is over” can breathe a sigh of relief now.

    However, if you get HIV, it does currently mean you will have to take those meds every day for the rest of your (no reason it shouldn’t be long and happy) life.

    So, HIV is definitely still something to avoid, because it’s not great to have to take a life-saving medication every day. For a little insight as to what that might be like:

    HIV.gov | Taking HIV Medication Every Day: Tips & Challenges

    (as you’ll see there, there are also longer-lasting injections available instead of daily pulls, but those are much less widely available)

    Summary

    Some quick take-away notes-in-a-nutshell:

    • Getting HIV may have been a death sentence in the 1980s, but nowadays it’s been relegated to the level of “serious inconvenience”.
    • Happily, it is very preventable, with PrEP, PEP, and viral loads so low that they can’t transmit HIV, thanks to ARVs.
    • Washing will not help, by the way. Safe sex will, though!
      • As will celibacy and/or sexual exclusivity in seroconcordant relationships, e.g. you have the same (known! That means actually tested recently! Not just assumed!) HIV status as each other.
    • If you do get it, it is very manageable with ARVs, but prevention is better than treatment
    • There is no certain cure—yet. Some people (small number of case studies) may have been cured already with gene therapy, but we can’t know for sure yet.

    Want to know more? Check out:

    CDC | Let’s Stop HIV Together

    Take care!

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    Adding up the sections make for an overall win for chia (especially if we were to consider the macros category for its full weight, given the importance of those components, but it’s still a 2:1 win for chia even if we pay no attention to that), but by all means enjoy either or both; diversity is good!

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  • The Doctor’s Kitchen – by Dr. Rupy Aujla

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    Click here to check out The Doctor’s Kitchen, and satisfy your taste buds—along with the rest of yoru body!

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