Nanotechnology vs Alcohol Damage!

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One Thing That Does Pair Well With Alcohol…

Alcohol is not a healthy thing to consume. That shouldn’t be a controversial statement, but there is a popular belief that it can be good for the heart:

Red Wine & The Heart: Can We Drink To Good Health?

The above is an interesting and well-balanced article that examines the arguments for health benefits (including indirectly, e.g. social aspects).

Ultimately, though, as the World Health Organization puts it:

WHO: No level of alcohol consumption is safe for our health

There is some good news:

We can somewhat reduce the harm done by alcohol by altering our habits slightly:

How To Make Drinking Less Harmful

…and we can also, of course, reduce our alcohol consumption (ideally to zero, but any reduction is an improvement already):

How To Reduce Or Quit Alcohol

And, saving the best news (in this section, anyway) for last, it is almost always possible to undo the harm done specifically to one’s liver:

How To Unfatty A Fatty Liver

Nanotechnology to the rescue?

Remember when we had a main feature about how colloidal gold basically does nothing by itself (and that that’s precisely why gold is used in medicine, when it is used)?

Now it has an extra bit of nothing to do, for our benefit (if we drink alcohol, anyway), as part of a gel that detoxifies alcohol before it can get to our liver:

Gold is one of the “ingredients” in a gel containing a nanotechnology lattice of protein fibrils coated with iron (and the gold is there as an inert catalyst, which is chemistry’s way of saying it doesn’t react in any way but it does cheer the actual reagents on). There’s more chemistry going on than we have room to discuss in our little newsletter, so if you like the full details, you can read about that here:

Single-site iron-anchored amyloid hydrogels as catalytic platforms for alcohol detoxification

The short and oversimplified explanation is that instead of alcohol being absorbed from the gut and transported via the bloodstream to the liver, where it is metabolized (poisoning the liver as it goes, and poisoning the rest of the body too, including the brain), the alcohol is degraded while it is still in the gastrointestinal tract, converted by the gel’s lattice into acetic acid (which is at worst harmless, and actually in moderation a good thing to have).

Even shorter and even more oversimplified: the gel turns the alcohol into vinegar in the stomach and gut, before it can get absorbed into the blood.

But…

Of course there’s a “but”…

There are some limitations:

It doesn’t get it all (tests so far found it only gets about half of the alcohol), and so far it’s only been tested on mice, so it’s not on the market yet—while the researchers are sufficiently confident about it that a patent application has now been made, though, so it’ll probably show up on the market in the near future.

You can read a pop-science article about it (with diagrams!) here:

New gel breaks down alcohol in the body

Want to read more…

…about how to protect your organs (including your brain) from alcohol completely?

We’ve reviewed quite a number of books about quitting alcohol, so it’s hard to narrow it down to a single favorite, but after some deliberation, we’ll finish today with recommending:

Quit Drinking – by Rebecca Doltonyou can read our review here

Take care!

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    ❓ Q&A With 10almonds Subscribers!

    Q: I like that the quizzes (I’ve done two so far) give immediate results , with no “give us your email to get your results”. Thanks!

    A: You’re welcome! That’s one of the factors that influences what things we include here! Our mission statement is “to make health and productivity crazy simple”, and the unwritten part of that is making sure to save your time and energy wherever we reasonably can!

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  • Dealing with Thirst!

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    Busting The Myth of “Eight Glasses Of Water A Day”

    Everyone knows we must drink 8 glasses of water a day, or else we’re going to get a failing grade at being a healthy human—like not flossing, or not using adequate sunscreen.

    But… Do we? And does tea count? How about (we dare but whisper it) coffee? And soda drinks are mostly water, right? But aren’t some drinks dehydrating? Are special electrolyte drinks really better? There are so many things to consider, so many differing advices, and it’s easy to give up, or just choose what to believe in as a leap of faith.

    A quick brain-teaser for you first, though:

    If coffee and soda don’t count because they’re dehydrating, then what if you were to take:

    – A concentrated tiny cup of espresso, and then a glass of water, would the glass of water count?

    Or (we don’t relish the thought) what if you took a spoonful of soda syrup, and then a glass of water, would the glass of water count?

    If your answer was “yes, it’s a glass of water”, then why would it not count if it were taken all at once (e.g. as an Americano coffee, or a regular soda)?

    If your answer was “yes, but that water might only offset the dehydration caused by the coffee/syrup, so I might only be breaking even”, then you were thinking about this the right way:

    How much water you need depends on many factors that can be affected by what else you are consuming and what else you are doing. Science loves averages, so eight glasses a day may be great if you are of average health, and average body size, in a temperate climate, doing moderate exercise, and so on and so on.

    If you’re not the most average person of all time? You may need to take into account a lot of factors, ranging from what you ate for dinner to how much you perspired during your morning exercises. As you (probably) don’t live in laboratory conditions, this can become an impossible task—and if you missed (or guessed incorrectly) even one factor, the whole calculation will be thrown off. But is there any other way to know?

    What of the infamous pee test? Drink enough to make your urine as clear as possible, and if it’s dark, you’re dehydrated, common wisdom says.

    In reality, however, that tells you not what’s in your body, but rather, what got ejected from your body. If your urine is dark, it might mean you had too little water, but it also could just mean you had the right amount of water but too much sodium, for instance. A study of this was done on athletes, and found no correlation between urine color and actual bodily hydration when measured directly via a blood test.

    So, if we can’t just have an app tell us “drink this many glasses of water”, and we can’t trust urine color, what can we do?

    What we can do is trust that our body comes with (for free!) a wonderful homeostatic system and it will try to correct any imbalances. If you are thirsty, you’re dehydrated. Drink something with plenty of water in, if not plain water.

    But what about special electrolyte drinks? If you need salts, you will crave them. Craving a salty snack? Go for it! Or if you prefer not to snack, do a salt lick test (just put a little salt on your finger, and taste it; if it tastes good, wait a minute or two, and then have a little more, and repeat until it doesn’t).

    Bonus Tip:

    1. Make sure you always have a source of hydration (that you enjoy!) to hand. Maybe it’s chilled water, maybe it’s a pot of tea, maybe it’s a sports drink, it doesn’t matter too much. Even coffee is actually fine, by the way (but don’t overdo it).
    2. Make a personal rule: “I will always make time for hydration”. That means, if you’re thirsty, have something with water in it now. Not when you’ve finished what you’re doing (unless you really can’t stop, because you are a racecar driver mid-race, or a surgeon mid-operation, or something), but now. Do not postpone it until after you’ve done some other thing first; you will forget and it will keep getting postponed. Always make time for water.

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  • Avoid Knee Surgery With This Proven Strategy (Over-50s Specialist Physio)

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    A diagnosis of knee arthritis can be very worrying, but it doesn’t necessarily mean a knee replacement surgery is inevitable. Here’s how to keep your knee better, for longer (and potentially, for life):

    Flexing your good health

    You know we wouldn’t let that “proven” go by unchallenged if it weren’t, so what’s the evidence for it? Research (papers linked in the video description) showed 70% of patients (so, not 100%, but 70% is good odds and a lot better than the alternative) with mild to moderate knee arthritis avoided surgery after following a specific protocol—the one we’re about to describe.

    The key strategy is to focus on strengthening the quadriceps muscles for joint protection, as strong quads correlate with reduced pain. However, a full range of motion in the knee is essential for optimal quad function, so that needs attention too, and in fact is foundational (can’t strengthen a quadriceps that doesn’t have a range of motion available to it):

    Steps to follow:

    1. Improve knee extension:
      • Passive knee extension exercise: gently press your knee down while lying flat, to increase straightening.
      • Weighted heel props: use light weights to encourage gradual knee straightening.
    2. Enhance knee flexion:
      • Use a towel to gently pull the knee towards the body to improve bending range.

    Regular practice (multiple times daily) leads to improved knee function and pain relief. Exercises should be performed gently and without pain, aiming for consistent, gradual progress.And of course, if you do experience pain, it is recommend to consult with a local physiotherapist for more personalized guidance.

    For more on all of this plus visual demonstrations, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like to read:

    Treat Your Own Knee – by Robin McKenzie

    Take care!

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  • The Joy of Saying No – by Natalie Lue

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    Superficially, this seems an odd topic for an entire book. “Just say no”, after all, surely! But it’s not so simple as that, is it?

    Lue looks into what underpins people-pleasing, first. Then, she breaks it down into five distinct styles of people-pleasing that each come from slightly different motivations and ways of perceiving how we interact with those around us.

    Lest this seem overly complicated, those five styles are what she calls: gooding, efforting, avoiding, saving, suffering.

    She then looks out how to have a healthier relationship with our yes/no decisions; first by observing, then by creating healthy boundaries. “Healthy” is key here; this isn’t about being a jerk to everyone! Quite the contrary, it involves being honest about what we can and cannot reasonably take on.

    The last section is about improving and troubleshooting this process, and constitutes a lot of the greatest value of the book, since this is where people tend to err the most.

    Bottom line: this book is informative, clear, and helpful. And far from disappointing everyone with “no”, we can learn to really de-stress our relationships with others—and ourselves.

    Click here to check out The Joy of Saying No, and have more energy for the right “yes” items in your life!

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  • Calm Your Mind with Food – by Dr. Uma Naidoo

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    From the author of This Is Your Brain On Food, the psychiatrist-chef (literally, she is a Harvard-trained psychiatrist and an award-winning chef) is back with a more specific work, this time aimed squarely at what it says in the title; how to calm your mind with food.

    You may be wondering: does this mean comfort-eating? And, well, not in the sense that term’s usually used. There will be eating and comfort will occur, but the process involves an abundance of nutrients, a minimization of health-deleterious ingredients, and a “for every chemical its task” approach. In other words, very much “nutraceuticals”, as our diet.

    On which note: as we’ve come to expect from Dr. Naidoo, we see a lot of hard science presented simply and clearly, with neither undue sensationalization nor unnecessary jargon. We learn about the brain, the gut, relevant biology and chemistry, and build up from understanding ingredients to dietary patterns to having a whole meal plan, complete with recipes.

    You may further be wondering: how much does it add that we couldn’t get from the previous book? And the answer is, not necessarily a huge amount, especially if you’re fairly comfortable taking ideas and creating your own path forwards using them. If, on the other hand, you’re a little anxious about doing that (as someone perusing this book may well be), then Dr. Naidoo will cheerfully lead you by the hand through what you need to know and do.

    Bottom line: if not being compared to her previous book, this is a great standalone book with a lot of very valuable content. However, the previous book is a tough act to follow! So… All in all we’d recommend this more to people who want to indeed “calm your mind with food”, who haven’t read the other book, as this one will be more specialized for you.

    Click here to check out Calm Your Mind With Food, and do just that!

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  • What Do The Different Kinds Of Fiber Do? 30 Foods That Rank Highest

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    We’ve talked before about how important fiber is:

    Why You’re Probably Not Getting Enough Fiber (And How To Fix It)

    And even how it’s arguably the most important dietary factor when it comes to avoiding heart disease:

    What Matters Most For Your Heart? Eat More (Of This) For Lower Blood Pressure ← Spoiler: it’s fiber

    And yes, that’s even when considered alongside other (also laudable) dietary interventions such as lowering intake of sodium, various kinds of saturated fat, and red meat.

    So, what should we know about fiber, aside from “aim to get nearer 40g/day instead of the US average 16g/day”?

    Soluble vs Insoluble

    The first main way that dietary fibers can be categorized is soluble vs insoluble. Part of the difference is obvious, but bear with us, because there’s more to know about each:

    • Soluble fiber dissolves (what a surprise) in water and, which part is important, forms a gel. This slows down things going through your intestines, which is important for proper digestion and absorption of nutrients (as well as avoiding diarrhea). Yes, you heard right: getting enough of the right kind of fiber helps you avoid diarrhea.
    • Insoluble fiber does not dissolve (how shocking) in water and thus mostly passes through undigested by us (some will actually be digested by gut microbes who subsist on this, and in return for us feeding them daily, they make useful chemicals for us). This kind of fiber is also critical for healthy bowel movements, because without it, constipation can ensue.

    Both kinds of fiber improve just about every metric related to blood, including improving triglycerides and improving insulin sensitivity and blood glucose levels. Thus, they help guard against various kinds of cardiovascular disease, diabetes, and metabolic disease in general. Do note that because whatever’s good for your heart/blood is good for your brain (which requires a healthy heart and bloodstream to nourish it and take away waste), likely this also has a knock-on effect against cognitive decline, but we don’t have hard science for that claim so we’re going to leave that last item as a “likely”.

    However, one thing’s for sure: if you want a healthy gut, heart, and brain, you need a good balance of soluble and insoluble fibers.

    10 of the best for soluble fiber

    FoodSoluble Fiber Type(s)Soluble Fiber (g per serving)Insoluble Fiber Type(s)Insoluble Fiber (g per serving)Total Fiber (g per serving)
    Kidney beans (1 cup cooked)Pectin, Resistant Starch1.5–2Hemicellulose, Cellulose68
    Lentils (1 cup cooked)Pectin, Resistant Starch1.5–2Cellulose67.5
    Barley (1 cup cooked)Beta-glucan3–4Hemicellulose26
    Brussels sprouts (1 cup cooked)Pectin1–1.5Cellulose, Hemicellulose23.5
    Oats (1 cup cooked)Beta-glucan2–3Cellulose13
    Apples (1 medium)Pectin1–2Cellulose, Hemicellulose23
    Carrots (1 cup raw)Pectin1–1.5Cellulose, Hemicellulose23
    Citrus fruits (orange, 1 medium)Pectin1–1.5Cellulose12.5
    Flaxseeds (2 tbsp)Mucilage, Lignin1–1.5Cellulose12.5
    Psyllium husk (1 tbsp)Mucilage3–4Trace amounts03–4

    10 of the best for insoluble fiber

    FoodSoluble Fiber Type(s)Soluble Fiber (g per serving)Insoluble Fiber Type(s)Insoluble Fiber (g per serving)Total Fiber (g per serving)
    Wheat bran (1 cup)Trace amounts0Cellulose, Lignin6–86–8
    Black beans (1 cup cooked)Pectin, Resistant Starch1.5Cellulose67.5
    Brown rice (1 cup cooked)Trace amounts0.5Hemicellulose, Lignin2–32.5–3.5
    Popcorn (3 cups popped)Trace amounts0.5Hemicellulose33.5
    Broccoli (1 cup cooked)Pectin1Cellulose, Hemicellulose45
    Green beans (1 cup cooked)Trace amounts0.5Cellulose, Hemicellulose33.5
    Sweet potatoes (1 cup cooked)Pectin1–1.5Cellulose34.5
    Whole wheat bread (1 slice)Trace amounts0.5Cellulose, Hemicellulose11.5
    Pears (1 medium)Pectin1Cellulose, Hemicellulose45
    Almonds (1 oz)Trace amounts0.5Cellulose, Hemicellulose22.5

    10 of the best for a balance of both

    FoodSoluble Fiber Type(s)Soluble Fiber (g per serving)Insoluble Fiber Type(s)Insoluble Fiber (g per serving)Total Fiber (g per serving)
    Raspberries (1 cup)Pectin1Cellulose56
    Edamame (1 cup cooked)Pectin1Cellulose56
    Chia seeds (2 tbsp)Mucilage, Pectin2–3Lignin, Cellulose35.5
    Artichokes (1 medium)Inulin1Cellulose, Hemicellulose56
    Avocado (1 medium)Pectin~2Cellulose46
    Black beans (1 cup cooked)Pectin, Resistant Starch1.5Cellulose67.5
    Quinoa (1 cup cooked)Pectin, Saponins1Cellulose, Hemicellulose34
    Spinach (1 cup cooked)Pectin0.5Cellulose, Lignin33.5
    Prunes (1/2 cup)Pectin, Sorbitol2Cellulose46
    Figs (3 medium)Pectin1Cellulose23

    You’ll notice that the above “balance” is not equal; that’s ok; we need greater quantities of insoluble than soluble anyway, so it is as well that nature provides such.

    This is the same kind of balance when we talk about “balanced hormones” (does not mean all hormones are in equal amounts; means they are in the right proportions) or “balanced microbiome” (does not mean that pathogens and friendly bacteria are in equal numbers), etc.

    Some notes on the above:

    About those fiber types, some of the most important soluble ones to aim for are:

    • Beta-glucan: found in oats and barley, it supports heart health.
    • Pectin: found in fruits like apples, citrus, and pears, it helps with cholesterol control.
    • Inulin: a type of prebiotic fiber found in artichokes.
    • Lignin: found in seeds and wheat bran, it has antioxidant properties.
    • Resistant starch: found in beans and lentils, it acts as a prebiotic for gut health.

    See also: When Is A Fiber Not A Fiber? The Food Additive You Do Want

    One fiber to rule them all

    Well, not entirely (we still need the others) but there is a best all-rounder:

    The Best Kind Of Fiber For Overall Health?

    Enjoy!

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