What you need to know about FLiRT, an emerging group of COVID-19 variants

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What you need to know

  • COVID-19 wastewater levels are currently low, but a recent group of variants called FLiRT is making headlines.
  • KP.2 is one of several FLiRT variants, and early lab tests suggest that it’s more infectious than JN.1.
  • Getting infected with any COVID-19 variant can cause severe illness, heart problems, and death.

KP.2, a new COVID-19 variant, is now dominant in the United States. Lab tests suggest that it may be more infectious than JN.1, the variant that was dominant earlier this year.

Fortunately, there’s good news: Current wastewater data shows that COVID-19 infection rates are low. Still, experts are closely watching KP.2 to see if it will lead to an uptick in infections.

Read on to learn more about KP.2 and how to stay informed about COVID-19 cases in your area.

Where can I find data on COVID-19 cases in my area?

Hospitals are no longer required to report COVID-19 hospital admissions or hospital capacity to the Department of Health and Human Services. However, wastewater-based epidemiology (WBE) estimates the number of COVID-19 infections in a community based on the amount of COVID-19 viral particles detected in local wastewater.

View this map of wastewater data from the CDC to visualize COVID-19 infection rates throughout the U.S., or look up COVID-19 wastewater trends in your state.

What do we know so far about the new variant?

Early lab tests suggest that KP.2—one of a group of emerging variants called FLiRT—is similar to the previously dominant variant, JN.1, but it may be more infectious. If you had JN.1, you may still get reinfected with KP.2, especially if it’s been several months or longer since your last COVID-19 infection.

A CDC spokesperson said they have no reason to believe that KP.2 causes more severe illness than other variants. Experts are closely watching KP.2 to see if it will lead to an uptick in COVID-19 cases.

How can I protect myself from COVID-19 variants?

Staying up to date on COVID-19 vaccines reduces your risk of severe illness, long COVID, heart problems, and death. The CDC recommends that people 65 and older and immunocompromised people receive an additional dose of the updated COVID-19 vaccine this spring.

Wearing a high-quality, well-fitting mask reduces your risk of contracting COVID-19 and spreading it to others. At indoor gatherings, improving ventilation by opening doors and windows, using high-efficiency particulate air (HEPA) filters, and building your own Corsi-Rosenthal box can also reduce the spread of COVID-19.

This article first appeared on Public Good News and is republished here under a Creative Commons license.

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    Find what’s best for you realistically. Have an 80% perfect diet 80% of the time, rather than a perfect diet for a few meals.

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  • Mung Beans vs Red Lentils – Which is Healthier?

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    Our Verdict

    When comparing mung beans to red lentils, we picked the lentils.

    Why?

    Both are great! But the lentils win on overall nutritional density.

    In terms of macros, they have approximately the same carbs and fiber, and are both low glycemic index foods. The deciding factor is that the lentils have slightly more protein—but it’s not a huge difference; both are very good sources of protein.

    In the category of vitamins, mung beans have more of vitamins A, E, and K, while red lentils have more of vitamins B1, B2, B3, B5, B6, B9, C, and choline. An easy win for lentils.

    When it comes to minerals, again both are great, but mung beans have more calcium and magnesium (hence the green color) while red lentils have more copper, iron, manganese, phosphorus, potassium, selenium, and zinc. Another clear win for lentils.

    Polyphenols are also a worthy category to note here; both have plenty, but red lentils have more, especially flavonols, anthocyanidins, proanthocyanidins, and anthocyanins (whence the red color).

    In short: enjoy both, because diversity is almost always best. But if you’re picking one, red lentils are the most nutritious of the two.

    Want to learn more?

    You might like to read:

    Sprout Your Seeds, Grains, Beans, Etc

    Take care!

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  • Chickpeas vs Soybeans – Which is Healthier?

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    Our Verdict

    When comparing chickpeas to soybeans, we picked the soybeans.

    Why?

    Both are great! But:

    In terms of macros, chickpeas have more than 3x the carbs and only very slightly more fiber, while soybeans have more than 2x the protein. Given the ratio of carbs to fiber in each, soybeans also have the lower glycemic index, so all in all, we’re calling this a win for soybeans.

    In the category of vitamins, chickpeas have more of vitamins A, B3, B5, and B9, while soybeans have more of vitamins B1, B2, B6, C, K, and choline—another win for soybeans.

    When it comes to minerals, chickpeas have more manganese and zinc, while soybeans have more calcium, copper, iron, magnesium, phosphorus, potassium, and selenium—meaning soybeans win yet again.

    Two extra things to know:

    • Chickpeas are naturally high in FODMAPs, which can be problematic for a minority of people—however, canned chickpeas are not.
    • Soybeans are famously high in phytoestrogens, however, the human body cannot actually use these as estrogen (we are not plants and our physiology is different). This means that on the one hand they won’t help against menopause (aside from the ways in which any nutrient-dense food would help), but on the other, they aren’t a cancer risk, and no, they won’t feminize men/boys in the slightest. You/they would be more at risk from beef and dairy, as the cows have usually been given extra estrogen, and those are animal hormones, not plant hormones.

    All in all, chickpeas are a wonderful food, but soybeans beat them by most nutritional metrics.

    Want to learn more?

    You might like to read:

    Why You Can’t Skimp On Amino Acids ← soybeans also have a great amino acid profile!

    Enjoy!

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  • Who Initiates Sex & Why It Matters

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    In an ideal world, it wouldn’t matter any more than who first says “let’s get something to eat” when hungry. But in reality, it can cause serious problems on both sides:

    Fear and loathing?

    The person who initiates gets the special prize of an n% chance of experiencing rejection, and then what? Try again, and again, and risk seeming pushy? Or leave the ball in the other person’s court, where it may then go untouched for the next few months, because (in the most positive scenario) they were waiting for you to initiate at a better time for them?

    The person who does not initiate, and/but does not want sex at that time, gets the special prize of either making their partner feel unwanted, insecure, and perhaps unloved, or else grudgingly consenting to sex that’s going to be no fun while your heart’s not in it, and thus create the same end result plus you had an extra bad experience?

    So, that sucks all around:

    • Initiating touch (sex or cuddling) can feel like a test of being wanted, whereupon a lack of initiation or response may be misinterpreted as a lack of love or appreciation.
    • Meanwhile, non-reciprocation might stem from exhaustion or unrelated issues. For many, it’s a physiological lottery.

    10almonds note: not discussed in this video, but for many couples, problems can also arise because one partner or another just isn’t showing up with the expected physical signs of physiological arousal, so even if they say (and mean!) an enthusiastic “yes”, their body’s signs get misread as a “not really, though”, resulting in one partner feeling rejected, and both feeling inadequate—on account of something that was completely unrelated to how the person actually felt about the prospect of sex*.

    *Sometimes, physiological arousal will simply not accompany psychological arousal, no matter how sincere the latter. And on the flipside, sometimes the signs of physiological arousal will just show up without psychological arousal. The human body is just like that sometimes. We all must listen to our partners’ words, not their genitals!

    The solution to this problem is thus the same as the solution to the rest of the problem that is discussed in the video, and it’s: good communication.

    That can be easier said than done, of course—not everyone is at their most eloquent in such situations! Which is why it can be important to have those conversations first outside of the bedroom when the stakes are low/non-existent.

    Even with the best communication, a more general, overarching non-reciprocity (real or perceived) of sexual desire can cause bitterness, resentment, and can ultimately be relationship-ending if a resolution that’s acceptable to everyone involved is not found.

    Ultimately, the work as a couple must begin from within as individuals—addressing self-worth issues to better navigate love and intimacy.

    For more on all of this, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like to read:

    Relationships: When To Stick It Out & When To Call It Quits

    Take care!

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  • Ginkgo Biloba, For Memory And, Uh, What Else Again?

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    Ginkgo biloba, for memory and, uh, what else again?

    Ginkgo biloba extract has enjoyed use for thousands of years for an assortment of uses, and has made its way from Traditional Chinese Medicine, to the world supplement market at large. See:

    Ginkgo biloba: A Treasure of Functional Phytochemicals with Multimedicinal Applications

    But what does the science say about the specific claims?

    Antioxidant & anti-inflammatory

    We’re going to lump these two qualities together for examination, since one invariably leads to the other.

    A quick note: things that have antioxidant and anti-inflammatory properties, often also help guard against cancer and aging. However, in this case, there are few good studies pertaining to anti-aging, and none that we could find pertaining to anti-cancer potential.

    So, does it have antioxidant and anti-inflammatory properties, first?

    Yes, it has potent antioxidants that do fight inflammation; this is clear, from an abundance of in vitro and in vivo studies, including with human patients:

    In short: it helps, and there’s plenty of science for it.

    What about anti-aging effects?

    For this, there is science, but a lot of the science is not great. As one team of researchers concluded while doing a research review of their own:

    ❝Based on the reviewed information regarding EGb’s effects in vitro and in vivo, most have reported very positive outcomes with strong statistical analyses, indicating that EGb must have some sort of beneficial effect.

    However, information from the reported clinical trials involving EGb are hardly conclusive since many do not include information such as the participant’s age and physical condition, drug doses administered, duration of drug administered as well as suitable control groups for comparison.

    We therefore call on clinicians and clinician-scientists to establish a set of standard and reliable standard operating procedure for future clinical studies to properly evaluate EGb’s effects in the healthy and diseased person since it is highly possible it possesses beneficial effects.❞

    Translation from sciencese: “These results are great, but come on, please, we are begging you to use more robust methodology”

    ~ Zuo et al

    If you’d like to read the review in question, here it is:

    Advances in the Studies of Ginkgo Biloba Leaves Extract on Aging-Related Diseases

    Does it have cognitive enhancement effects?

    The claims here are generally that it helps:

    • improve memory
    • improve focus
    • reduce cognitive decline
    • reduce anxiety and depression

    Let’s break these down:

    Does it improve memory and cognition?

    Ginkgo biloba was quite popular for memory 20+ years ago, and perhaps had an uptick in popularity in the wake of the 1999 movie “Analyze This” in which the protagonist psychiatrist mentions taking ginkgo biloba, because “it helps my memory, and I forget what else”.

    Here are a couple of studies from not long after that:

    In short:

    • in the first study, it helped in standardized tests of memory and cognition (quite convincing)
    • In the second study, it helped in subjective self-reports of mental wellness (also placebo-controlled)

    On the other hand, here’s a more recent research review ten years later, that provides measures of memory, executive function and attention in 1132, 534 and 910 participants, respectively. That’s quite a few times more than the individual studies we cited above, by the way. They concluded:

    ❝We report that G. biloba had no ascertainable positive effects on a range of targeted cognitive functions in healthy individuals❞

    ~ Laws et al

    Read: Is Ginkgo biloba a cognitive enhancer in healthy individuals? A meta-analysis

    Our (10almonds) conclusion: we can’t say either way, on this one.

    Does it have neuroprotective effects (i.e., against cognitive decline)?

    Yes—probably by the same mechanism will discuss shortly.

    Can it help against depression and anxiety?

    Yes—but probably indirectly by the mechanism we’ll get to in a moment:

    Likely this helps by improving blood flow, as illustrated better per:

    Efficacy of ginkgo biloba extract as augmentation of venlafaxine in treating post-stroke depression

    Which means…

    Bonus: improved blood flow

    This mechanism may support the other beneficial effects.

    See: Ginkgo biloba extract improves coronary blood flow in healthy elderly adults

    Is it safe?

    Ginkgo biloba extract* is generally recognized as safe.

    • However, as it improves blood flow, please don’t take it if you have a bleeding disorder.
    • Additionally, it may interact badly with SSRIs, so you might want to avoid it if you’re taking such (despite it having been tested and found beneficial as an adjuvant to citalopram, an SSRI, in one of the studies above).
    • No list of possible contraindications can be exhaustive, so please consult your own doctor/pharmacist before taking something new.

    *Extract, specifically. The seeds and leaves of this plant are poisonous. Sometimes “all natural” is not better.

    Where can I get it?

    As ever, we don’t sell it (or anything else), but here’s an example product on Amazon

    Enjoy!

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  • Foot Drop!

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    It’s Q&A Day at 10almonds!

    Have a question or a request? We love to hear from you!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    ❝Interesting about DVT after surgery. A friend recently got diagnosed with foot drop. Could you explain that? Thank you.❞

    First, for reference, the article about DVT after surgery was:

    DVT Risk Management Beyond The Socks

    As for foot drop…

    Foot drop is descriptive of the main symptom: the inability to raise the front part of the foot due to localized weakness/paralysis. Hence, if a person with foot drop dangles their feet over the edge of the bed, for example, the affected foot will simply flop down, while the other (if unaffected) can remain in place under its own power. The condition is usually neurological in origin, though there are various more specific causes:

    NIH | StatPearls | Foot Drop

    When walking unassisted, this will typically result in a distinctive “steppage gait”, as it’s necessary to lift the foot higher to compensate, or else the toes will scuff along the ground.

    There are mobility aids that can return one’s walking to more or less normal, like this example product on Amazon.

    Incidentally, the above product will slightly shorten the lifespan of shoes, as it will necessarily pull a little at the front.

    There are alternatives that won’t like this example product on Amazon, but this comes with the different problem that it limits the user to stepping flat-footedly, which is not only also not an ideal gait, but also, will serve to allow any muscles down there that were still (partially or fully) functional to atrophy. For this reason, we’d recommend the first product we mentioned over the second one, unless your personal physiotherapist or similar advises otherwise (because they know your situation and we don’t).

    Both have their merits, though:

    Trends and Technologies in Rehabilitation of Foot Drop: A Systematic Review

    Of course, prevention is better than cure, so while some things are unavoidable (especially when it comes to neurological conditions), we can all look after our nerve health as well as possible along the way:

    Peripheral Neuropathy: How To Avoid It, Manage It, Treat It

    …as well as the very useful:

    What Does Lion’s Mane Actually Do, Anyway?

    …which this writer personally takes daily and swears by (went from frequent pins-and-needles to no symptoms and have stayed that way, and that’s after many injuries over the years).

    If you’d like a more general and less supplements-based approach though, check out:

    Steps For Keeping Your Feet A Healthy Foundation

    Take care!

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  • Most People Who Start GLP-1 RAs Quit Them Within A Year (Here’s Why)

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    Specifically, 54% quit within one year, with that number rising to 72% within two years.

    We first wrote about GLP-1 receptor agonists (i.e. semaglutide drugs like Ozempic and Wegovy) a couple of years ago when popularity was just beginning to take off:

    Semaglutide for Weight Loss?

    However, as we had room only to touch briefly on the side effects and what happens when you stop taking it, you might also want to check out:

    What happens when I stop taking a drug like Ozempic or Mounjaro?

    …and:

    Considering taking Wegovy to lose weight? Here are the risks and benefits – and how it differs from Ozempic

    Notwithstanding all this information, there’s a lot of science that has still yet to be done. If you’re a regular 10almonds reader, you’ll be familiar with our research review articles—this one was more of a non-research review, i.e. looking at the great absence of evidence in certain areas, and the many cases of research simply not asking the right questions, for example:

    Of the four studies that actually looked at the macros (unlike most studies), they found that on average, protein intake decreased by 17.1%. Which is a big deal!

    It’s an especially big deal, because while protein’s obviously important for everyone, it’s especially important for anyone trying to lose weight, because muscle mass is a major factor in metabolic base rate—which in turn is much important for fat loss/maintenance than exercise, when it comes to how many calories we burn by simply existing.

    A reasonable hypothesis, therefore, is that one of the numerous reasons people who quit GLP-1 agonists immediately put fat back on, is because they probably lost muscle mass in amongst their weight loss, meaning that their metabolic base rate will have decreased, meaning that they end up more disposed to put on fat than before.❞

    Read in full: Semaglutide’s Surprisingly Unexamined Effects ← there are a lot more (equally concerning) items discussed in this article

    Why people quit GLP-1 RAs

    There was a large (n=125,474) study of US adults. The average age was about 54 years, and about 65% were female.

    From the total data pool (i.e. not narrowing it down by demographic), 54% stopped within a year, and 72% within two years.

    The factors most associated with discontinuation were:

    • age above 65 years
    • not having type 2 diabetes

    The main reasons given for discontinuation were:

    • High costs: self-explanatory, but it’s worth noting that people who stopped for this reason were more likely to restart later.
    • Adverse side effects: the most common ones were nausea, vomiting, diarrhea, constipation, stomach pain, and loss of appetite. Rarer, but more seriously, side effects included: pancreatitis (severe abdominal pain, nausea, vomiting), gallbladder issues (gallstones, cholecystitis), kidney problems, severe allergic reactions (rash, swelling, difficulty breathing), hypoglycemia, especially if taken with insulin or other diabetes medications, changes in vision (worsening diabetic retinopathy), and an increased heart rate.
    • Disappointingly little weight loss: the researchers noted that GLP-1 RA results are “heterogenous”, meaning, they differ a lot. For those for whom it didn’t work, quitting was more likely, for obvious reasons. See also: 10 Mistakes To Sabotage Your Ozempic Progress
    • Successful weight loss: while it is widely known that if one stops taking GLP-1 RAs, weight regain is the usual next thing to happen, there are a lot of people who go onto GLP-1 RAs with the rationale “I’ll just use this to lose the weight, and then I’ll keep the weight off with my diet and lifestyle”. Which sounds reasonable, but because of the specific mechanisms of actions of GLP-1 RAs, it simply doesn’t work that way (and, as we mentioned above, there are reasons that you may, after stopping taking GLP-1 RAs, be more disposed to put weight on than you were before you started). So, by the best of current science (which admittedly is not amazing when it comes to this topic), it does seem that taking GLP-1 RAs is a lifetime commitment.

    You can read the study itself here:

    Discontinuation and Reinitiation of Dual-Labeled GLP-1 Receptor Agonists Among US Adults With Overweight or Obesity

    Want to get similar results, without GLP-1 RAs?

    Then check out:

    5 Ways To Naturally Boost The “Ozempic Effect” ← this is about natural ways of doing similar hormone-hacking to what GLP-1 RAs do

    and

    Ozempic vs Five Natural Supplements ← this is about metabolism-tweaking supplements

    and

    Hack Your Hunger ← this is about appetite management

    Take care!

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