What is HRT? HRT and Hormones Explained

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In this short video, Dr. Sophie Newton explains how menopausal HRT, sometimes called just MHT, is the use of exogenous (didn’t come from your body) to replace/supplement the endogenous hormones (made in your body) that aren’t being made in the quantities that would result in ideal health.

Bioidentical hormones are, as the name suggests, chemically identical to those made in the body; there is no difference, all the way down to the atomic structure.

People are understandably wary of “putting chemicals into the body”, but in fact, everything is a chemical and those chemicals are also found in your body, just not in the numbers that we might always like.

In the case of hormones, these chemical messengers are simply there to tell cells what to do, so having the correct amount of hormones ensures that all the cells that need to get a certain message, get it.

In the case of estrogen specifically, while it’s considered a sex hormone (and it is), it’s responsible for a lot more than just the reproductive system, which is why many people without correct estrogen levels (such as peri- or post-menopause, though incorrect levels can happen earlier in life for other reasons too) can severely feel their absence in a whole stack of ways.

What ways? More than we can list here, but some are discussed in the video:

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Want to know more?

You might like our previous main features:

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  • Age & Aging: What Can (And Can’t) We Do About It?

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    How old do you want to be?

    We asked you how old you are, and got an interesting spread of answers. This wasn’t too surprising; of course we have a general idea of who our readership is and we write accordingly.

    What’s interesting is the gap for “40s”.

    And, this wasn’t the case of a broken poll button, it’s something that crops up a lot in health-related sociological research. People who are most interested in taking extra care of their body are often:

    • Younger people full of optimism about maintaining this perfectly healthy body forever
    • Older people realizing “if I don’t want to suffer avoidable parts of age-related decline, now is the time to address these things”

    In between, we often have a gap whereby people no longer have the optimism of youth, but do not yet feel the pressure of older age.

    Which is not to say there aren’t 40-somethings who do care! Indeed, we know for a fact we have some subscribers in their 40s (and some in their 90s, too), just, they evidently didn’t vote in this poll.

    Anyway, let’s bust some myths…

    Aging is inevitable: True or False?

    False, probably. That seems like a bold (and fortune-telling) claim, so let’s flip it to deconstruct it more logically:

    Aging is, and always will be, unstoppable: True or False?

    That has to be “False, probably”. To say “true” now sounds like an even bolder claim. Just like “the moon will always be out of reach”.

    • When CPR was first developed, first-aiders were arrested for “interfering with a corpse”.
    • Many diseases used to be death sentences that are now “take one of these in the morning”
      • If you think this is an appeal to distant history, HIV+ status was a death sentence in the 90s. Now it’s “take one of these in the morning”.

    But, this is an appeal to the past, and that’s not always a guarantee of the future. Where does the science stand currently? How is the research and development doing on slowing, halting, reversing aging?

    We can slow aging: True or False?

    True! There’s a difference between chronological age (i.e., how much time has passed while we’ve been alive) and biological age (i.e., what our diverse markers of aging look like).

    Biological age often gets talked about as a simplified number, but it’s more complex than that, as we can age in different ways at different rates, for example:

    • Visual markers of aging (e.g. wrinkles, graying hair)
    • Performative markers of aging (e.g. mobility tests)
    • Internal functional markers of aging (e.g. tests for cognitive decline, eyesight, hearing, etc)
    • Cellular markers or aging (e.g. telomere length)
    • …and more, but we only have so much room here

    There are things we can do to slow most of those, including:

    In the case of cognitive decline particularly, check out our previous article:

    How To Reduce Your Alzheimer’s Risk

    It’s too early to worry about… / It’s too late to do anything about… True or False?

    False and False!

    Many things that affect our health later in life are based on early-life choices and events. So it’s important for young people to take advantage of that. The earlier one adopts a healthy lifestyle, the better, because, and hold onto your hats for the shocker here: aging is cumulative.

    However, that doesn’t mean that taking up healthy practices (or dropping unhealthy ones) is pointless later in life, even in one’s 70s and beyond!

    Read about this and more from the National Institute of Aging:

    What Do We Know About Healthy Aging?

    We can halt aging: True or False?

    False, for now at least. Our bodies are not statues; they are living organisms, constantly rebuilding themselves, constantly changing, every second of every day, for better or for worse. Every healthy or unhealthy choice you make, every beneficial or adverse experience you encounter, affects your body on a cellular level.

    Your body never, ever, stops changing for as long as you live.

    But…

    We can reverse aging: True or False?

    True! Contingently and with limitations, for now at least.

    Remember what we said about your body constantly rebuilding itself? That goes for making itself better as well as making itself worse.

    But those aren’t really being younger, we’ll still die when our time is up: True or False?

    False and True, respectively.

    Those kinds of things are really being younger, biologically. What else do you think being biologically younger is?

    We may indeed die when our time is up, but (unless we suffer fatal accident or incident first) “when our time is up” is something that is decided mostly by the above factors.

    Genetics—the closest thing we have to biological “fate”—accounts for only about 25% of our longevity-related health*.

    Genes predispose, but they don’t predetermine.

    *Read more: Human longevity: Genetics or Lifestyle? It takes two to tango

    (from the Journal of Immunity and Ageing)

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  • Vaginal Probiotics: What Does The Science Say?

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    It’s Q&A Day at 10almonds!

    Have a question or a request? We love to hear from you!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small 😎

    ❝Is there any merit to vaginal probiotics?❞

    What a fun question! First let’s break it down, as this could mean two different things:

    1. Probiotics, which you consume, using your mouth, which are marketed as benefiting vaginal health
    2. Probiotics taken as a vaginal pessary/suppository, to act directly there

    The former has limited evidence for it, but generally speaking, improving one’s gut health improves all other areas of health, so it’s not surprising if it helps this too.

    See for example:

    Ingestion of yogurt containing Lactobacillus acidophilus compared with pasteurized yogurt as prophylaxis for recurrent candidal vaginitis and bacterial vaginosis

    Some notes:

    • candidal vaginitis means a yeast infection causing vaginal inflammation
    • bacterial vaginosis means a vaginal bacterial imbalance (generally also featuring vaginal inflammation, though it can be asymptomatic)

    In the latter case, the “imbalance” in question is usually a shortage of Lactobacillus sp. (that is to say, the diverse species of the Lactobacillus genus) resulting in an overgrowth of other kinds of bacteria, which in turn results in changing the vaginal microbiome to make it warmer and more acidic than it should be.

    While a healthy vagina shouldn’t smell of roses, it shouldn’t smell fishy either; if it does, that’s a sign of bacterial vaginosis.

    What it’s supposed to be like: slightly bitter, slightly salty, distinctly umami, along with a cocktail of personal pheromones (and if menstruating or otherwise* vaginally bleeding, then of course add: iron/”metallic”). The pheromones will also reflect any hormonal changes, but should never make anything smell bad, just different.

    *e.g. due to PCOS, fibroids, etc. Note that in the case of PCOS, it may also smell a little different (if it does, then usually: a little more musky), due to often different hormone levels. Again: it still shouldn’t smell bad, though, just different.

    In the above-linked study, taking more live Lactobacillus acidophilus (in yogurt, eating it, with their mouths) improved levels of L. acidophilus in the vagina. While the study authors concluded “this ingestion of yogurt may have reduced episodes of bacterial vaginosis”, which is rather a weak claim, it can be argued that it merely improving the levels of L. acidophilus in the vagina was already a win.

    That was a small (n=42, and only 7 followed through to completion) and old (1996) study, and it bears mentioning that most of the studies into this seem to be small and old, but conclude similarly with weakly positive statements.

    However, it does make a difference what kind of Lactobacillus is used, for example in this next study…

    • L. fermentum RC-14 worked well (90% success rate)
    • L. rhamnosus GR-1 worked somewhat (40% success rate)
    • L. rhamnosus GG did not work (0% success rate)

    So, diversity is key, and getting a wide range of Lactobacillus sp. seems to be a safe bet.

    Short version: enjoying probiotics as part of your diet probably improves vaginal health, just like it improves pretty much everything else.

    See also: Make Friends With Your Gut (You Can Thank Us Later)

    You would think that this would mean that taking probiotics as a vaginal pessary/suppository would be even better, but the results are weaker, as in this study, which produced temporary improvements in about half the study group, with only 3 out of 28 being free of bacterial vaginosis the next month:

    Treatment of bacterial vaginosis with lactobacilli

    This study got better results, with a 61% success rate:

    Effectiveness of Lactobacillus-containing vaginal tablets in the treatment of symptomatic bacterial vaginosis

    Important note

    Do note that this last category, involving topical treatments (i.e., manually introducing Lactobacillus sp. to the vagina) were all in cases of pre-existing bacterial vaginosis, not as a prophylactic and/or general health-improving thing.

    If your vagina seems happy right now, then do not mess with its happy bacterial balance!

    And at all times (regardless of whether it seems happy right now or not): do not douche (it does not need it and will not benefit from it; the vagina is self-cleaning*) as this will wash out many of your Lactobacilli and will do absolutely nothing against any Candida there (C. albicans being a rooted fungus, whereas Lactobacillus is a sausage-shaped bacterium with many tiny appendages but no actual ability to stay put), so Candida will flourish in the Lactobacillus’s absence.

    *by the vagina, we are referring to the vaginal canal. The vulva—the outside part consisting of the two pairs of labia, the glans clitoris, and clitoral hood—are not self-cleaning, and should just be washed gently per your normal bath/shower routine; that’s perfectly fine and good.

    And definitely don’t put any “cleansing” toiletries inside the vagina (or any toiletries at all, for that matter), even if they are sold and marketed for that purpose; they will not help and they will harm.

    Also, due to their neighborliness, messing up the microbiome inside the vagina is a common way to also get Candida inside the urethra:

    How To Avoid Urinary Tract Infections (UTIs)

    One other option

    Finally, unless you have a “very good friend” you have a pressing urge to swap germs with, you might want to leave this one to the scientists, but we share this paper just for interest:

    The effectiveness of vaginal microbiota transplantation for vaginal dysbiosis and bacterial vaginosis: a scoping review

    Lastly…

    Going back to oral supplementation, if you’d like to try that then check out this for further notes on what, why, how, etc:

    How Much Difference Do Probiotic Supplements Make To Health?

    Take care!

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  • Avocado Oil vs Olive Oil – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing avocado oil to olive oil, we picked the olive oil.

    Why?

    Avocados and olives are both very healthy foods. However, when they are made into oils, there’s an important distinguishing factor:

    Olive oil usually retains a lot of the micronutrients from the olives (including vitamins E and K), whereas no measurable micronutrients usually remain in avocado oil.

    So while both olive oil and avocado oil have a similar (excellent; very heart-healthy!) lipids profile, the olive oil has some bonuses that the avocado oil doesn’t.

    We haven’t written about the nutritional profiles of either avocados or olives yet, but here’s what we had to say on the different kinds of olive oil available:

    Is “Extra Virgin” Worth It?

    And here’s an example of a good one on Amazon, for your convenience 😎

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Related Posts

  • Exercises for Aging-Ankles
  • Understanding Spinach Oxalates and Health

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s Q&A Day at 10almonds!

    Have a question or a request? You can always hit “reply” to any of our emails, or use the feedback widget at the bottom!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    ❝Interesting, but… Did you know spinach is high in oxylates? Some people are sensitive and can cause increased inflammation, joint pain or even kidney stones. Moderation is key. My sister and I like to eat healthy but found out by experience that too much spinach salad caused us joint and other aches.❞

    It’s certainly good to be mindful of such things! For most people, a daily serving of spinach shouldn’t cause ill effects, and certainly there are other greens to eat.

    We wondered whether there was a way to reduce the oxalate content, and we found:

    How to Reduce Oxalic Acid in Spinach: Neutralizing Oxalates

    …which led us this product on Amazon:

    Nephure Oxalate Reducing Enzyme, Low Oxalate Diet Support

    We wondered what “nephure” was, and whether it could be trusted, and came across this “Supplement Police” article about it:

    Nephure Review – Oxalate Reducing Enzyme Powder Health Benefits?

    …which honestly, seems to have been written as a paid advertisement. But! It did reference a study, which we were able to look up, and find:

    In vitro and in vivo safety evaluation of Nephure™

    …which seems to indicate that it was safe (for rats) in all the ways that they checked. They did not, however, check whether it actually reduced oxalate content in spinach or any other food.

    The authors did declare a conflict of interest, in that they had a financial relationship with the sponsor of the study, Captozyme Inc.

    All in all, it may be better to just have kale instead of spinach:

    Don’t Forget…

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  • Atomic Habits – by James Clear

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    James Clear’s Atomic Habits has become “the” go-to book about the power of habit-forming. And, there’s no shortage of competition out there, so that’s quite a statement. What makes this book stand out?

    A lot of books start by assuming you want to build habits. That can seem a fair assumption; after all, we picked up the book! But an introductory chapter really hammers home the idea in a way that makes it a lot more motivational:

    • Habits are the compound interest of productivity
    • This means that progress is not linear, but exponential
    • Habits can also be stacked, and thus become synergistic
    • The more positive habits you add incrementally, the easier they become because each thing is making your life easier/better

    For example:

    • It’s easier to save money if you’re in good health
    • It’s easier to sleep better if you do not have financial worries
    • It’s easier to build your relationship with your loved ones if you’re not tired

    …and so on.

    For many people this presents a Catch-22 problem! Clear instead presents it as an opportunity… Start wherever you like, but just start small, with some two-minute thing, and build from there.

    A lot of the book is given over to:

    • how to form effective habits (using his “Four Laws”)
    • how to build them into your life
    • how to handle mishaps
    • how to make sure your habits are working for you
    • how to see habits as part of your identity, and not just a goal to be checked off

    The last one is perhaps key—goals cease to be motivating once accomplished. Habits, on the other hand, keep spiralling upwards (if you guide them appropriately).

    There’s lots more we could say, but it’s a one-minute book review, so we’ll just close by saying:

    This book can help you to become the kind of person who genuinely gets a little better each day, and reaps the benefits over time.

    Get your copy of Atomic Habits from Amazon today!

    Don’t Forget…

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  • The Lymphatic System Against Cancer & More

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    Ask Not What Your Lymphatic System Can Do For You…

    Just kidding; we’ll cover that first, as it’s definitely not talked about enough.

    The lymphatic system is the system in the body that moves lymph around. It’s made of glands, nodes, and vessels:

    • The glands (such as the tonsils and the adenoids) and nodes filter out bacteria and produce white blood cells. Specific functions may be, well, specialized—beyond the scope of today’s article—but that’s the broad function.
    • The vessels are the tubes that allow those things to be moved around, suspended in lymph.

    What’s lymph? It’s a colorless water-like liquid that transports immune cells, nutrients (and waste) around the body (through the lymphatic system).

    Yes, it works alongside your vasculature; when white blood cells aren’t being deployed en masse into your bloodstream to deal with some threat, they’re waiting in the wings in the lymphatic system.

    While your blood is pumped around by your heart, lymph moves based on a variety of factors, including contractions of small specialized lymphatic muscles, the pressure gradient created by the combination of those and gravity, and the movements of your body itself.

    Here’s a larger article than we have room for, with diagrams we also don’t have room for:

    Modelling the lymphatic system

    To oversimplify it in few words for the sake of moving on: you can most of the time: think of it as an ancillary network supporting your circulatory system that unlike blood, doesn’t deal with oxygen or sugars, but does deal with a lot of other things, including:

    • water and salt balance
    • immune cells and other aspects of immune function
    • transports fats (and any fat-soluble vitamins in them) into circulation
    • cleans up stuff that gets stuck between cells
    • general detoxification

    There’s a lot that can go wrong if lymph isn’t flowing as it should

    Too much to list here, but to give an idea:

    • Arthritis and many autoimmune diseases
    • Cardiovascular disease and metabolic syndrome
    • Obesity, diabetes, and organ failure
    • Alzheimer’s and other dementias
    • Lymphadenitis, lymphangitis, and lymphedenopathy
    • Lymphomas and Hodgkin’s disease (both are types of lymphatic cancer)
    • Cancers of other kinds, because of things not being cleaned up where and when they should be

    Yikes! That’s a lot of important things for a mostly-forgotten system to be taking care of protecting us from!

    What you can do for your lymphatic system, to avoid those things!

    Happily, there are easy things we can do to give our lymph some love, such as:

    Massage therapy (and foam rolling)

    This is the go-to that many people/publications recommend. It’s good! It’s certainly not the most important thing to do, but it’s good.

    You can even use a simple gadget like this one to help move the lymph around, without needing to learn arcane massage techniques.

    Exercise (move your body!)

    This is a lot more important. The more we move our body, the more lymph moves around. The more lymph moves around today, the more easily it will move around tomorrow. A healthy constant movement of lymph throughout the lymphatic system is key to keeping everything running smoothly.

    If you pick only one kind of exercise, make it High-Intensity Interval Training (HIIT):

    How To Do HIIT (Without Wrecking Your Body)

    If for some reason you really can’t do that, just spend as much of your waking time as reasonably possible, moving, per:

    Exercise Less; Move More

    For ideas on how to do that, check out…

    No-Exercise Exercise!

    Get thee to a kitchen

    This is about getting healthy food that gives your body’s clean-up crew (the lymphatic system) an easier time of it.

    Rather than trying to “eat clean” which can be a very nebulous term and it’s often not at all clear (and/or hotly debated) what counts as “clean”, instead, stick to foods that constitute an anti-inflammatory diet:

    Eat To Beat Inflammation

    Take care!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails: