The How Not to Die Cookbook – by Dr. Michael Greger
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We’ve previously reviewed Dr. Greger’s “How Not To Die”, which is excellent and/but very science-dense.
This book is different, in that the science is referenced and explained throughout, but the focus is the recipes, and how to prepare delicious healthy food in accordance with the principles laid out in How Not To Die.
It also follows “Dr Greger’s Daily Dozen“, that is to say, the 12 specific things he advises we make sure to have every day, and thus helps us to include them in an easy, no-fuss fashion.
The recipes themselves are by Robin Robertson, and/but with plenty of notes by Dr Greger; they clearly collaborated closely in creating them.
The ingredients are all things one can find in any well-stocked supermarket, so unless you live in a food desert, you can make these things easily.
And yes, the foods are delicious too.
Bottom line: if you’re interested in cooking according to perhaps the most science-based dietary system out there, then this book is a top-tier choice.
Click here to check out The How Not To Die Cookbook, and live well!
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The Good Life – by Robert Waldinger, MD, and Marc Schulz, PhD
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For any who have thought “there must be some middle-ground between entirely subjective self-help books advising how to feel better, and sifting through clinical data on what actually affects people’s moods“, this book is exactly that middle-ground!
Drs. Waldinger and Schultz went through the 80-year-long Harvard Study of Adult Development with a fine-toothed comb, and this book details—more readably—what they found.
There are frequent references to data from the study. Not just numbers, though, people’s answers to questions, too. And how different factors about people’s lives affected their answers to the same questions.
We hear from all ages, from young adults to octagenarians, and learn how attitudes (including: of the same people) change over time. Not because people are fickle, but because people grow… or become disillusioned. Or sometimes, both.
We learn about the importance of money… And where that importance ends.
We learn importance of relationships of various kinds, and this is certainly a recurring theme throughout the study—and thus, throughout the book.
The book doesn’t just present data, though, it also presents actionable insights along the way.
Bottom line: the combined wisdom and life-experiences of a lot of people provide a very “big picture” view of life, and what makes us happy, really. We highly recommend it!
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How Not To Get Sick: A Cookbook – by Dr. Benjamin Bikman and Diana Keuilian
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We’ve previously reviewed Dr. Bikman’s excellent “Why We Get Sick”, and if you haven’t read that yet, we recommend doing so.
Nevertheless, you don’t need to have read it to benefit from this one, which is about cooking with those learnings (from the other book) in mind.
Before getting to the recipes, we get a section recapping what we learned previously, as well as adding some more general lifestyle advices beyond the kitchen. The science is also expanded a bit, to include such things as the two-way relationship between insulin and aging, as well as the interplay with other metrics of health, including blood lipids, for example.
The authors then provide a plan, in the three stages: reverse (insulin resistance), prevent (insulin resistance), maintain (insulin sensitivity).
The recipes themselves, of which there are 70, are of course tailored to do the above three things; they’re also quite diverse, albeit if you are vegetarian or vegan, you should know in advance that most of these recipes are not.
Bottom line: if the above doesn’t apply to you, and you would like to improve your insulin sensitivity, this book can indeed help.
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The Checklist Manifesto – by Dr. Atul Gawande
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Dr. Gawande, himself a general surgeon, uses checklists a lot. He is, unequivocally, an expert in his field. He “shouldn’t” need a checklist to tell him to do such things as “Check you have the correct patient”. But checklists are there as a safety net. And, famously, “safety regulations are written in blood”, after all.
And, who amongst us has never made such a “silly” error? From forgetting to turn the oven on, to forgetting to take the handbrake off, it takes only a momentary distraction to think we’ve done something we haven’t.
You may be wondering: why a whole book on this? Is it just many examples of the usefulness of checklists? Because I’m already sold on that, so, what else am I going to get out of it?
Dr. Gawande also explains in clear terms:
- How to optimize “all necessary steps” with “as few steps as possible”
- The important difference between read-do checklists and do-confirm checklists
- To what extent we should try to account for the unexpected
- How to improve compliance (i.e., making sure you actually use it, no matter how tempting it will be to go “yeah this is automatic for me now” and gloss over it)
- The role of checklists in teams, and in passing on knowledge
…and more.
Bottom line: if you’ve ever tried to make tea without putting the tea-leaves in the pot, this is the book that will help you avoid making more costly mistakes—whatever your area of activity or interest.
Click here to check out the Checklist Manifesto, and make fewer mistakes!
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The Surprising Link Between Type 2 Diabetes & Alzheimer’s
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The Surprising Link Between Type 2 Diabetes & Alzheimer’s
This is Dr. Rhonda Patrick. She’s a biomedical scientist with expertise in the areas of aging, cancer, and nutrition. In the past five years she has expanded her research of aging to focus more on Alzheimer’s and Parkinson’s, as she has a genetic predisposition to both.
What does that genetic predisposition look like? People who (like her) have the APOE-ε4 allele have a twofold increased risk of Alzheimer’s disease—and if you have two copies (i.e., one from each of two parents), the risk can be up to tenfold. Globally, 13.7% of people have at least one copy of this allele.
So while getting Alzheimer’s or not is not, per se, hereditary… The predisposition to it can be passed on.
What’s on her mind?
Dr. Patrick has noted that, while we don’t know for sure the causes of Alzheimer’s disease, and can make educated guesses only from correlations, the majority of current science seems to be focusing on just one: amyloid plaques in the brain.
This is a worthy area of research, but ignores the fact that there are many potential Alzheimer’s disease mechanisms to explore, including (to count only mainstream scientific ideas):
- The amyloid hypothesis
- The tau hypothesis
- The inflammatory hypothesis
- The cholinergic hypothesis
- The cholesterol hypothesis
- The Reelin hypothesis
- The large gene instability hypothesis
…as well as other strongly correlated factors such as glucose hypometabolism, insulin signalling, and oxidative stress.
If you lost your keys and were looking for them, and knew at least half a dozen places they might be, how often would you check the same place without paying any attention to the others?
To this end, she notes about those latter-mentioned correlated factors:
❝50–80% of people with Alzheimer’s disease have type 2 diabetes; there is definitely something going on❞
There’s another “smoking gun” for this too, because dysfunction in the blood vessels and capillaries that line the blood-brain barrier seem to be a very early event that is common between all types of dementia (including Alzheimer’s) and between type 2 diabetes and APOE-ε4.
Research is ongoing, and Dr. Patrick is at the forefront of that. However, there’s a practical take-away here meanwhile…
What can we do about it?
Dr. Patrick hypothesizes that if we can reduce the risk of type 2 diabetes, we may reduce the risk of Alzheimer’s with it.
Obviously, avoiding diabetes if possible is a good thing to do anyway, but if we’re aware of an added risk factor for Alzheimer’s, it becomes yet more important.
Of course, all the usual advices apply here, including a Mediterranean diet and regular moderate exercise.
Three other things Dr. Patrick specifically recommends (to reduce both type 2 diabetes risk and to reduce Alzheimer’s risk) include:
(links are to her blog, with lots of relevant science for each)
You can also hear more from Dr. Patrick personally, as a guest on Dr. Peter Attia’s podcast recently. She discusses these topics in much greater detail than we have room for in our newsletter:
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A Supplement To Rival St. John’s Wort Against Depression
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Do You Feel The SAMe?
S-Adeonsyl-L-Methionone (SAMe) is a chemical found naturally in the body, and/but enjoyed widely as a supplement. The main reasons people take it are:
- Improve mood (antidepressant effect)
- Improve joints (reduce osteoarthritis symptoms)
- Improve liver (detoxifying effect)
Let’s see what the science says for each of those claims…
Does it improve mood?
It seems to perform comparably to St. John’s Wort (which is good; it performs comparably to Prozac).
Best of all, it does this with fewer contraindications (St. John’s Wort has so many contraindications).
Here’s how they stack up:
This looks very promising, though it’d be nice to see a larger body of research, to be sure.
Does it reduce osteoarthritis symptoms?
The good news: it performs comparably to ibuprofen, with fewer side effects!
The bad news: it also performs comparably to placebo!
Read into that what you will about ibuprofen’s usefulness vs OA symptoms.
Read all about it:
S-Adenosylmethionine for osteoarthritis of the knee or hip
If you were hoping for something for OA or similar symptoms, you might like our previous main features:
- Avoiding/Managing Osteoarthritis
- Managing Chronic Pain (Realistically!)
- The 7 Approaches To Pain Management
- (Science-Based) Alternative Pain Relief
Does it help against liver disease?
According to adverts for SAMe: absolutely!
According to science: we don’t know
The science for this is so weak that it’d be unworthy of mention if it weren’t for the fact that SAMe is so widely sold as good against hepatotoxicity.
To be clear: maybe it really is great! Science hasn’t yet disproved its usefulness either.
It is popularly assumed to be beneficial due to there being an association between lower levels of SAMe in the body (remember, it is also produced inside our bodies) and development of liver disease, especially cholestasis.
Here’s an example of what pretty much every study we found was like (inconclusive research based mostly on mice):
S-adenosylmethionine in liver health, injury, and cancer
For other options for liver health, consider:
Is it safe?
Safety trials have been done ranging from 3 months to 2 years, with no serious side effects coming to light. So, it appears quite safe.
That said, as with anything, there are contraindications, such as:
- if you have bipolar disorder, skip this unless directed by your health care provider, because it may worsen the symptoms of mania
- if you are on SSRIs or other serotonergic drugs, it may interact with those
- if you are immunocompromised, you might want to skip it can increase the risk of P. carinii growth in such cases
As always, do speak with your doctor/pharmacist for personalized advice.
Summary
SAMe’s evidence-based qualities seem to stack up as follows:
- Against depression: good
- Against osteoarthritis: weak
- Against liver disease: unknown
As for safety, it has been found quite safe for most people.
Where can I get it?
We don’t sell it, but here is an example product on Amazon, for your convenience
Enjoy!
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Are your Kidneys Ok? Detect Early To Protect Kidney Health (Here’s How)
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Tomorrow (at time of publication) will be World Kidney Day (WKD). Perhaps not the most well-known initiative, but it celebrates its 21st year this year!
For those of us who celebrated our own 21st year quite some time ago now, it’s as good a reason as any to check in on our kidney health.
Here are some things they’d like us to know about Chronic Kidney Disease (CKD):
❝CKD is a silent disease, people with CKD have no signs or symptoms until the late stage of the disease.
CKD usually does not go away, instead, it progresses, unless early treatment to slow or halt the disease is ensured.
CKD can progress to kidney failure – a condition when kidneys cannot maintain their function anymore, posing a life-threatening risk.
CKD ranks number 7 in the top ten causes of death among noncommunicable diseases worldwide.
CKD increases the risk of premature death from associated cardiovascular disease.
CKD is more common among certain ethnic groups due in part to high rates of diabetes and high blood pressure.
CKD is more common among women, here is why.❞Source: World Kidney Day: Your Amazing Kidneys
How can we check our kidney health?
There are clinical tests that can be done (they’ll just need a urine sample from you; ask your doctor about it), but there’s some screening that can be done at home already:
Are Your Kidneys Healthy? Take This One-Minute Quiz To Find out
👆 this is about medical indicators; there are also non-medical factors that affect risk, including:
- Where someone lives
- Where they work
- The foods they eat
- How much exercise they do
- If they are able to get the medical care they need
For more information on this, see: Keeping Your Kidneys Healthy (Especially After 60) ← there’s a lot more to it than just hydration!
What can we do for our kidney health, besides the obvious “hydrate”?
Some top things to do include:
Hydrate, yes. See also: Things Many People Forget When It Comes To Hydration
Don’t smoke. It’s bad for everything, including your kidneys. So, just don’t. See also: Addiction Myths That Are Hard To Quit
Look after your blood. Not just “try to keep it inside your body”, but also:
- Keep your blood sugar levels healthy (hyperglycemia can cause kidney damage)
- Keep your blood pressure healthy (hypertension can cause kidney damage)
Basically, your kidneys’ primary job of filtering blood will go much more smoothly if that blood is less problematic on the way in.
Watch your over-the-counter pill intake. A lot of PRN OTC NSAIDs (PRN = pro re nata, i.e. you take them as and when symptoms arise) (NSAIDs = Non-Steroidal Anti-Inflammatory Drugs, such as ibuprofen for example) can cause kidney damage if taken regularly.
Keep an eye on your urine. Hydration is only one side of the story, and our urine can say quite a bit about our health. Indeed, we have written about this before:
12 Things Your Urine Says About Your Health (Test At Home) ← no special equipment required!
On which note, see also: To Pee Or Not To Pee ← spoiler: there’s a flood of reasons to not hold your pee
Want to know more?
Check out the WKD website’s…
8 Golden Rules Of Kidney Disease Prevention
Take care!
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