The Good, The Bad, & The Vigorously Debated

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This week in health news sees some pretty varied topics:

One more reason to care about the gut-brain axis

Stroke is a top killer in much of the industrialized world, usually making it into the top-few list on a per-country basis. And, it’s rising in prevalence, too. This is partly because our longevity is increasing so age-related things kill us more often, statistically, than age-unrelated things. But that’s only part of the reason; another is that our lifestyle (on the national level) is becoming more conducive to stroke. Diet is a large contributor to that, and gut health has now been identified as a key factor.

What recent research has shown is that minutes after a stroke occurs, normal gut anatomy is disrupted, and cells responsible for gut barrier integrity are eroded, and bugs from the gut get into the blood, and arrive at the (newly damaged) brain vasculature, where the blood-brain barrier is often also compromised on account of the stroke.

Because of this, critical to reducing post-stroke neuroinflammation (something that makes stroke damage more severe and recovery a lot harder) is improving the gut’s ability to heal itself quickly.

This can be helped with a dose of Insulin-like Growth Factor (IGF-1), but there are other things that can help or hinder, and those other things are modifiable by us as individuals in our lifestyle choices (e.g. a gut-healthy diet with plenty of fiber, and avoiding gut-unhealthy things like sugar and alcohol that feed C. albicans growths that will put roots through your intestines and make holes as they do), because the better/worse your gut barrier integrity is to start with, the easier/harder it will be for your gut to repair itself quickly:

Read in full: Healing the gut can reduce long-term impact of stroke

Related: Stop Sabotaging Your Gut

How about that seasonal lead-spiced hot drink?

Lead contamination in ground spices has become a bit of an issue, ground turmeric has had quite some flak in this regard, and now the spotlight is on cinnamon.

These reports, by the way, do not specify what kind of cinnamon (i.e. cassia vs Ceylon), however, clicking through to assorted sources and then doing our own digging finds that all cinnamon products we found listed as contaminated, were cassia cinnamon. This is unsurprising, as a) it’s cheaper b) it’s the kind most readily found on shelves in the US. That said, when it comes to Ceylon (sweet) cinnamon, absence of evidence is not evidence of absence, so that doesn’t mean they got the all-clear on lead contamination, but rather, that they haven’t received the same scrutiny as yet.

It’s worth noting that cinnamon sticks have been found to have less contamination than ground cinnamon, though.

It’s also worth noting that since some adulterated products have had lead added deliberately in increase the weight and darken the color, this is more likely to happen to cassia cinnamon than sweet cinnamon because cassia cinnamon is visibly darker, so adding a darkening agent to sweet cinnamon would just make it look like cassia (which no seller would want to do since cassia is the cheaper of the two).

Read in full: Why lead-tainted cinnamon products have turned up on shelves, and what questions consumers should ask

Related: Sweet Cinnamon vs Regular Cinnamon – Which is Healthier? ← this also covers toxicity issues, by the way

A matter of life and death

Assisted dying is currently legal in 10/40 US states, and Canada. Over in the UK, it’s being debated (and voted on) in Parliament today, at time of writing.

While bodily autonomy discussions are usually quite straightforward arguments between the very separate camps of

  • “my body, my choice” vs
  • “they shouldn’t be allowed to do that”,

…this one comes with a considerable middleground, because

  • “people should have to right to end things without extra suffering and on their own terms”, and
  • “many disabled people fear being placed in a position of having justify why they are not exercising their right to die when it might be cheaper and easier for others if they did”

…are positions with a lot of potential overlap.

In any case, we know most of our readers are in the US, but with a 10/40 split in US states (and some recent controversies in Canada), it’s likely a topic that’ll come up for most people at some point, so it’s good to understand it, and this is as good an opportunity as any:

Read in full: How would the assisted dying bill work and what issues might it create?

Related: Managing Your Mortality ← this talks about psychological/social considerations, as well as end-of-life care, palliative care (which is not quite the same thing!) and euthanasia in various forms, including the unofficial kind that you might want to be aware of if you want to avoid that happening.

Take care!

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  • How to survive extreme cold

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    Cold weather can be deadly, especially in places not used to extreme cold. A December 2024 study found that cold-related deaths have more than doubled between 1999 and 2022, with over 3,500 deaths reported in 2022. 

    Climate change doesn’t only mean rising temperatures; it also causes extreme weather, including extreme cold

    The Cybersecurity and Infrastructure Security Agency defines extreme cold as “temperatures that are lower than historical averages to the point that it creates a dangerous environment for people, animals, and critical infrastructure.”

    “There’s rightfully been a focus on heat deaths because of the context of global warming. But both can be true,” said Michael Liu, the study’s lead author, in a Washington Post article. “Cold-related deaths are still a public health risk.” 

    Cold weather-related injuries and deaths are preventable. Preparing ahead of time ensures you can stay safe when cold weather hits.

    Stay informed 

    Following local news and weather reports will keep you aware of extreme weather in your area so you can plan accordingly. Many state and local governments provide emergency text and mobile app alert services.

    The National Weather Service automatically sends English and Spanish Wireless Emergency Alerts related to weather emergencies to compatible cell phones. Although iPhones, Androids, and most smartphones are WEA-compatible, you may need to check your device’s settings to ensure they are turned on. 

    Make a cold weather kit

    When planning for cold weather, prepare for the worst-case scenario. Extremely cold temperatures, snow, and ice can cause power outages, frozen or burst pipes, loss of wireless and cell signals, and hazardous driving conditions. 

    A cold weather kit for your home should include: 

    • A flashlight with extra batteries
    • A first-aid kit
    • Extra water and non-perishable food to last a few days
    • Baby supplies, such as diapers and formula to last a few days
    • Pet supplies, such as food and litter to last a few days
    • Warm clothes and blankets 
    • Sufficient amounts of your prescription medications and special medical equipment

    You may also wish to add a battery-powered NOAA weather radio in your kit. These radios, which can be purchased for as little as $20, allow you to receive weather updates during power and internet outages.

    Experts recommend staying indoors and avoiding driving in extreme cold. If you must drive, make sure your car has a cold weather kit before the winter. In addition to the equipment in a home cold weather kit, the National Weather Service suggests that a winter car survival kit also include:

    • Jumper cables
    • Cat litter or sand for tire traction 
    • Shovel 
    • Ice scraper
    • Blankets/sleeping bag and warm clothes
    • Hand warmers
    • Charged cell phone with a spare charger
    • Basic tool kit

    Become familiar with warming centers

    Many cities offer warming centers for people who need short-term shelter during cold weather. Check nearby centers’ locations, operating hours, and pet policies in advance. If your local warming centers don’t accept pets, other locations, like kennels and vet clinics, may temporarily board pets.

    Learn how to use heating and power devices safely

    Many deaths in cold weather are not from cold temperatures but from fires and carbon monoxide poisoning from improper use of heaters and generators. 

    All living spaces should be equipped with working smoke and carbon monoxide detectors, which should be tested monthly. Some fire departments provide free and low-cost detectors.

    According to the Federal Emergency Management Agency, heaters are the second leading cause of house fires. 

    “Space heaters are involved in more than 1,000 home fires across the country every year and factor into the vast majority of home heating-related deaths,” said former Department Of Homeland Security Secretary Alejandro Mayorkas at FEMA’s 2024 #WinterReady Extreme Cold Summit.

    Space heaters should never be left unattended, used around unsupervised children or pets, or left on overnight. They should be plugged directly into a power outlet, not power strips and extension cords. Additionally, they shouldn’t be operated on unstable or uneven surfaces.

    The U.S. Fire Administration also recommends that you “keep anything that can burn at least 3 feet from all heat sources including fireplaces, wood stoves, radiators, space heaters or candles.”

    Generators and portable coal- or gasoline-powered power stations can help you stay warm and maintain power during outages. However, these devices should never be used indoors, as they produce deadly carbon monoxide. Generators should be set up outdoors, at least 20 feet from vents, windows, and doors. 

    Carbon monoxide poisoning can also be a risk when trying to stay warm inside a vehicle. To avoid this, never leave your car running inside a garage, even if the door and windows are open. 

    For more information about cold weather resources, check with your local government and FEMA and the National Weather Service.

    This article first appeared on Public Good News and is republished here under a Creative Commons license.

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  • Intuitive Eating Might Not Be What You Think

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    In our recent Expert Insights main features, we’ve looked at two fairly opposing schools of thought when it comes to managing what we eat.

    First we looked at:

    What Flexible Dieting Really Means

    …and the notion of doing things imperfectly for greater sustainability, and reducing the cognitive load of dieting by measuring only the things that are necessary.

    And then in opposition to that,

    What Are The “Bright Lines” Of Bright Line Eating?

    …and the notion of doing things perfectly so as to not go astray, and reducing the cognitive load of dieting by having hard-and-fast rules that one does not second-guess or reconsider later when hungry.

    Today we’re going to look at Intuitive Eating, and what it does and doesn’t mean.

    Intuitive Eating does mean paying attention to hunger signals (each way)

    Intuitive Eating means listening to one’s body, and responding to hunger signals, whether those signals are saying “time to eat” or “time to stop”.

    A common recommendation is to “check in” with one’s body several times per meal, reflecting on such questions as:

    • Do I have hunger pangs? Would I seek food now if I weren’t already at the table?
    • If I hadn’t made more food than I’ve already eaten so far, would that have been enough, or would I have to look for something else to eat?
    • Am I craving any of the foods that are still before me? Which one(s)?
    • How much “room” do I feel I still have, really? Am I still in the comfort zone, and/or am I about to pass into having overeaten?
    • Am I eating for pleasure only at this point? (This is not inherently bad, by the way—it’s ok to have a little more just for pleasure! But it is good to note that this is the reason we’re eating, and take it as a cue to slow down and remember to eat mindfully, and enjoy every bite)
    • Have I, in fact, passed the point of pleasure, and I’m just eating because it’s in front of me, or so as to “not be wasteful”?

    See also: Interoception: Improving Our Awareness Of Body Cues

    And for that matter: Mindful Eating: How To Get More Out Of What’s On Your Plate

    Intuitive Eating is not “80:20”

    When it comes to food, the 80:20 rule is the idea of having 80% of one’s diet healthy, and the other 20% “free”, not necessarily unhealthy, but certainly not moderated either.

    Do you know what else the 80:20 food rule is?

    A food rule.

    Intuitive Eating doesn’t do those.

    The problem with food rules is that they can get us into the sorts of problems described in the studies showing how flexible dieting generally works better than rigid dieting.

    Suddenly, what should have been our free-eating 20% becomes “wait, is this still 20%, or have I now eaten so much compared to the healthy food, that I’m at 110% for my overall food consumption today?”

    Then one gets into “Well, I’ve already failed to do 80:20 today, so I’ll try again tomorrow [and binge meanwhile, since today is already written off]”

    See also: Eating Disorders: More Varied (And Prevalent) Than People Think

    It’s not “eat anything, anytime”, either

    Intuitive Eating is about listening to your body, and your brain is also part of your body.

    • If your body is saying “give me sugar”, your brain might add the information “fruit is healthier than candy”.
    • If your body is saying “give me fat”, your brain might add the information “nuts are healthier than fried food”
    • If your body is saying “give me salt”, your brain might add the information “kimchi is healthier than potato chips”

    That doesn’t mean you have to swear off candy, fried food, or potato chips.

    But it does mean that you might try satisfying your craving with the healthier option first, giving yourself permission to have the less healthy option afterwards if you still want it (you probably won’t).

    See also:

    I want to eat healthily. So why do I crave sugar, salt and carbs?

    Want to know more about Intuitive Eating?

    You might like this book that we reviewed previously:

    Intuitive Eating – by Evelyn Tribole and Elyse Resch

    Enjoy!

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  • 10 Simple Japanese Habits For Healthier & Longer Life

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    You don’t have to be Japanese or live in Okinawa to enjoy the benefits of healthy longevity. A lot of it comes down to simple habits:

    Easy to implement

    We’ll not keep the 10 habits a mystery; they are:

    1. Start the day with hot water: drinking hot water in the morning helps with hydration, warming the body, and aiding digestion.
    2. Enjoy a hearty breakfast: Japanese breakfasts are traditionally filling, nutritious, and help promote energy and longevity. Typical components include rice, miso soup, fish, and pickles.
    3. Take balanced meals: Japanese education emphasizes nutrition from a young age, promoting balanced meals with proteins, fiber, and vitamins & minerals.
    4. Enjoy fermented foods: fermented foods, such as nattō and soy-based condiments, support digestion, heart health, and the immune system.
    5. Drink green tea and matcha: both are rich in health benefits; preparing matcha mindfully adds a peaceful ritual to daily life too.
    6. Keep the “80% full” rule: “hara hachi bu” encourages eating until 80% full, which can improve longevity and, of course, prevent overeating.
    7. Use multiple small dishes: small servings and a variety of dishes help prevent overeating and ensure a diverse intake of nutrients.
    8. Gratitude before and after meals: saying “itadakimasu” and “gochisousama” promotes mindful eating, and afterwards, good digestion. Speaking Japanese is of course not the key factor here, but rather, do give yourself a moment of reflection before and after meals.
    9. Use vinegar in cooking: vinegar, often used in sushi rice and sauces like ponzu, adds flavor and offers health benefits, mostly pertaining to blood sugar balance.
    10. Eat slowly: Eating at a slower pace will improve digestion, and can enhance satiety and prevent accidentally overeating.

    For more on all of these, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like to read:

    How To Get More Out Of What’s On Your Plate

    Take care!

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  • Can You Gain Muscle & Lose Fat At The Same Time?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s Q&A Day at 10almonds!

    Have a question or a request? We love to hear from you!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small 😎

    ❝Is it possible to lose fat and gain muscle at the same time, or do we need to focus on one and then the other, and if so, which order is best?❞

    Contrary to popular belief, you can do both simultaneously! However, it’s not as easy as doing just one or the other, which is why most bodybuilders, for example, have a “building phase” and a “cutting phase”.

    The reason it’s difficult is because of the diet. Growing muscle doesn’t just take protein and micronutrients; it takes energy as well, which must come from carbohydrates and/or fats. Therefore, it is tricky to eat enough to build muscle and to fuel the workouts that are required to build the muscle (you can’t hit the gym in a state of rabbit starvation* and expect to perform well at your workout), while at the same time not eating enough carbs/fats to have any excess to store as fat.

    *So-called because rabbit-meat is very lean, such that when during times of famine, European peasants tried to subsist off mostly rabbits, their health quickly plummeted for lack of energy. It’s also been called “salmon starvation”, apparently, for the same reason:

    How ancestral subsistence strategies solve salmon starvation and the “protein problem” of Pacific Rim resources

    In French it’s called “Mal de caribou” (caribou sickness), by the way. But you get the idea: eat too much lean protein without enough carbs/fats, and woe shall befall.

    So, if you want to do both at once, you need to be incredibly on top of your macros, and the bad news is, only you (or a coach working directly with you) can work out what precise macros requirements your body has, because it depends on your body and your activities.

    The easier “half-way house”

    We will get to the “building phase” and “cutting phase” of bodybuilders, but first, here’s an option that’s very worthy of consideration, and it is: forget about your weight and just focus on health while incidentally doing regular resistance exercises and HIIT.

    What will happen if you do this (assuming a healthy balanced diet, nothing special and without counting anything, but we’re talking at least mostly whole-foods, and at least mostly plants; the Mediterranean diet is great for this, as it is for most things) is:

    • The dietary approach described will gradually improve your metabolic health if it wasn’t already good. If it was already good, it’ll likely just maintain it, rather than improve it.
    • The resistance exercises will, if engaged with seriously (it has to be difficult to do, or your muscles won’t have any reason to grow), gradually build muscle. This will be very gradual, because you’re not eating for bodybuilding, nor optimizing your general lifestyle for same. Historically many women have feared lifting weights because they don’t want to “look like a weightlifter”, but the kinds of bodies that word brings to mind are not the kind that happen by accident (especially for women, with our different hormones guiding our bodies to a different composition); it takes a lot of single-minded dedication to specifically optimize size gains, for a long time.
    • The high-intensity interval training (HIIT) will more rapidly improve your metabolic health, and unlike most forms of exercise, it will actually result in a gradual reduction of fat, if you have superfluous fat to lose. This is because whereas most forms of cardio exercise increase the heartrate for a while but then have a corresponding metabolic slump afterwards to make up for it, HIIT confuses the heart (in a good way) which results in it having to grow stronger, and not doing any compensatory metabolic slump:

    How To Do HIIT (Without Wrecking Your Body) ← as well as the “how to”, this also gives some of the science behind it, too

    This will, thus, result in gradual gain of muscle and loss of fat—or if you take it easier with the exercise, then you can easily settle into just maintaining your body composition as it is, but that wasn’t the question today.

    So, there you have it, that’s how to do both at once! Now, if you want more dramatic results, then more dramatic methods are called for:

    What bodybuilders (mostly) do

    Matters of genetic predisposition and commonplace use of steroids aside, here’s how bodybuilders get that “lots of muscle, no fat” figure:

    1. First, get into “moderate” shape if not already there.
    2. Bulk up: eat amounts of food that will seem unreasonable to a non-bodybuilder; eating 2x or even 3x the “recommended” daily calorie amount is common; focus is typically on getting adequate (for bodybuilding purposes) protein while also carb-loading for workouts and getting at least enough fats for fat-soluble vitamins to work. In the gym, focus on doing sets of very few reps with the heaviest weights one can safely lift, while doing minimal cardio, and also sleeping a lot (9–12hrs per day), which is essential because this is putting a huge strain on the body and it needs a chance to recover and rebuild.
    3. Cut down: maintain protein intake (to at least mostly maintain muscles) while keeping carbs and fats low, doing cardio work (HIIT is still ideal) and running a calorie deficit for a short while (there is no use in trying to maintain a long-term calorie deficit; your body will try to save you from starvation by storing any fat it can and slowing your metabolism).

    Phases 2 and 3 are then cycled, alternating every month, or every 6 weeks, or every 2 months or so, depending on personal preferences and scheduling considerations (bodybuilders will often have competitions they are working towards, so they need to time things to be at the end of a cutting phase to look their “best” by bodybuilder standards).

    Disclaimer: bodybuilding is complex, and can be ruinous to the health if practised inexpertly, because of its extreme nature. We don’t recommend serious bodybuilding per se in general, but if you are going to do it, please consult with a professional bodybuilding coach, and do not rely on a few paragraphs from us that are intended only to give the most basic overview of how bodybuilders can approach the “gain muscle, lose fat” problem.

    Want to know more?

    We’ve written on some related topics previously; here’s a three-part series:

    1. How To Lose Weight (Healthily!)
    2. How To Build Muscle (Healthily!)
    3. How To Gain Weight (Healthily!) ← this one’s specifically about gaining healthy levels of fat, for any who want/need that

    And also:

    Can We Do Fat Redistribution? ← yes we can, but there are caveats

    Take care!

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  • How does cancer spread to other parts of the body?

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    All cancers begin in a single organ or tissue, such as the lungs or skin. When these cancers are confined in their original organ or tissue, they are generally more treatable.

    But a cancer that spreads is much more dangerous, as the organs it spreads to may be vital organs. A skin cancer, for example, might spread to the brain.

    This new growth makes the cancer much more challenging to treat, as it can be difficult to find all the new tumours. If a cancer can invade different organs or tissues, it can quickly become lethal.

    When cancer spreads in this way, it’s called metastasis. Metastasis is responsible for the majority (67%) of cancer deaths.

    Cells are supposed to stick to surrounding tissue

    Our bodies are made up of trillions of tiny cells. To keep us healthy, our bodies are constantly replacing old or damaged cells.

    Each cell has a specific job and a set of instructions (DNA) that tells it what to do. However, sometimes DNA can get damaged.

    This damage might change the instructions. A cell might now multiply uncontrollably, or lose a property known as adherence. This refers to how sticky a cell is, and how well it can cling to other surrounding cells and stay where it’s supposed to be.

    If a cancer cell loses its adherence, it can break off from the original tumour and travel through the bloodstream or lymphatic system to almost anywhere. This is how metastasis happens.

    Many of these travelling cancer cells will die, but some will settle in a new location and begin to form new cancers.

    Cancer cells
    Some cells settle in a new location.
    Scipro/Shutterstock

    Particular cancers are more likely to metastasise to particular organs that help support their growth. Breast cancers commonly metastasise to the bones, liver, and lungs, while skin cancers like melanomas are more likely to end up in the brain and heart.

    Unlike cancers which form in solid organs or tissues, blood cancers like leukaemia already move freely through the bloodstream, but can escape to settle in other organs like the liver or brain.

    When do cancers metastasise?

    The longer a cancer grows, the more likely it is to metastasise. If not caught early, a patient’s cancer may have metastasised even before it’s initially diagnosed.

    Metastasis can also occur after cancer treatment. This happens when cancer cells are dormant during treatment – drugs may not “see” those cells. These invisible cells can remain hidden in the body, only to wake up and begin growing into a new cancer months or even years later.

    For patients who already have cancer metastases at diagnosis, identifying the location of the original tumour – called the “primary site” – is important. A cancer that began in the breast but has spread to the liver will probably still behave like a breast cancer, and so will respond best to an anti-breast cancer therapy, and not anti-liver cancer therapy.

    As metastases can sometimes grow faster than the original tumour, it’s not always easy to tell which tumour came first. These cancers are called “cancers of unknown primary” and are the 11th most commonly diagnosed cancers in Australia.

    One way to improve the treatment of metastatic cancer is to improve our ways of detecting and identifying cancers, to ensure patients receive the most effective drugs for their cancer type.

    What increases the chances of metastasis and how can it be prevented?

    If left untreated, most cancers will eventually acquire the ability to metastasise.

    While there are currently no interventions that specifically prevent metastasis, cancer patients who have their tumours surgically removed may also be given chemotherapy (or other drugs) to try and weed out any hidden cancer cells still floating around.

    The best way to prevent metastasis is to diagnose and treat cancers early. Cancer screening initiatives such as Australia’s cervical, bowel, and breast cancer screening programs are excellent ways to detect cancers early and reduce the chances of metastasis.

    Older woman has mammogram
    The best way to prevent cancer spreading is to diagnose and treat them early.
    Peakstock/Shutterstock

    New screening programs to detect cancers early are being researched for many types of cancer. Some of these are simple: CT scans of the body to look for any potential tumours, such as in England’s new lung cancer screening program.

    Using artificial intelligence (AI) to help examine patient scans is also possible, which might identify new patterns that suggest a cancer is present, and improve cancer detection from these programs.

    More advanced screening methods are also in development. The United States government’s Cancer Moonshot program is currently funding research into blood tests that could detect many types of cancer at early stages.

    One day there might even be a RAT-type test for cancer, like there is for COVID.

    Will we be able to prevent metastasis in the future?

    Understanding how metastasis occurs allows us to figure out new ways to prevent it. One idea is to target dormant cancer cells and prevent them from waking up.

    Directly preventing metastasis with drugs is not yet possible. But there is hope that as research efforts continue to improve cancer therapies, they will also be more effective at treating metastatic cancers.

    For now, early detection is the best way to ensure a patient can beat their cancer.The Conversation

    Sarah Diepstraten, Senior Research Officer, Blood Cells and Blood Cancer Division, Walter and Eliza Hall Institute and John (Eddie) La Marca, Senior Resarch Officer, Walter and Eliza Hall Institute

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Melatonin: A Safe, Natural Sleep Aid?

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    Melatonin: A safe sleep supplement?

    Melatonin is a hormone normally made in our pineal gland. It helps regulate our circadian rhythm, by making us sleepy.

    It has other roles too—it has a part to play in regulating immune function, something that also waxes and wanes as a typical day goes by.

    Additionally, since melatonin and cortisol are antagonistic to each other, a sudden increase in either will decrease the other. Our brain takes advantage of this, by giving us a cortisol spike in the morning to help us wake up.

    As a supplement, it’s generally enjoyed with the intention of inducing healthy, natural, restorative sleep.

    Does it really induce healthy, natural, restorative, sleep?

    Yes! Well, “natural” is a little subject and relative, if you’re taking it as a supplement, but it’s something your body produces naturally anyway.

    Contrast with, for example, benzodiazepines (that whole family of medications with names ending in -azopan or -alozam), or other tranquilizing drugs that do not so much induce healthy sleep, but rather reduce your brain function and hopefully knock you out, and/but often have unwanted side effects, and a tendency to create dependency.

    Melatonin, unlike most of those drugs, does not create dependency, and furthermore, we don’t develop tolerance to it. In other words, the same dose will continue working (we won’t need more and more).

    In terms of benefits, melatonin not only reduces the time to fall asleep and increases total sleep time, but also (quite a bonus) improves sleep quality, too:

    Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders

    Because it is a natural hormone rather than a drug with many side effects and interactions, it’s also beneficial for those who need good sleep and/but don’t want tranquilizing:

    The Efficacy of Oral Melatonin in Improving Sleep in Cancer Patients with Insomnia: A Randomized Double-Blind Placebo-Controlled Study

    Any other benefits?

    Yes! It can also help guard against Seasonal Affective Disorder, also called seasonal depression. Because SAD is not just about “not enough light = not enough serotonin”, but also partly about circadian rhythm and (the body is not so sure what time of day it is when there are long hours of darkness, or even, in the other hemisphere / other time of year, long hours of daylight), melatonin can help, by giving your brain something to “anchor” onto, provided you take it at the same time each day. See:

    As a small bonus, melatonin also promotes HGH production (important for maintaining bone and muscle mass, especially in later life):

    Melatonin stimulates growth hormone secretion through pathways other than the growth hormone-releasing hormone

    Anything we should worry about?

    Assuming taking a recommended dose only (0.5mg–10mg per day), toxicity is highly unlikely, especially given that it has a half-life of only 40–60 minutes, so it’ll be eliminated quite quickly.

    However! It does indeed induce sleepiness, so for example, don’t take melatonin and then try to drive or operate heavy machinery—or, ideally, do anything other than go to bed.

    It can interfere with some medications. We mentioned that melatonin helps regulate immune function, so for example that’s something to bear in mind if you’re on immunosuppressants or otherwise have an autoimmune disorder. It can also interfere with blood pressure medications and blood thinners, and may make epilepsy meds less effective.

    As ever, if in doubt, please speak with your doctor and/or pharmacist.

    Where to get it?

    As ever, we don’t sell it (or anything else), but for your convenience, here is an example product on Amazon.

    Enjoy!

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