Resveratrol & Healthy Aging

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Resveratrol & Healthy Aging

Resveratrol is the compound found in red grapes, and thus in red wine, that have resulted in red wine being sometimes touted as a heart-healthy drink.

However, at the levels contained in red wine, you’d need to drink 100–1000 glasses of wine per day (depending on the wine) to get the dose of resveratrol that were associated with heart health benefits in mouse studies.

(if you are not a mouse, you might need to drink even more than that)

Further reading: can we drink to good health?

Resveratrol supplementation

Happily, resveratrol supplements exist. But what does resveratrol do?

It lowers blood pressure:

Effect of resveratrol on blood pressure: a meta-analysis of randomized controlled trials

It improves blood lipid levels:

Consumption of resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: a triple-blind, 6-month follow-up, placebo-controlled, randomized trial

It improves insulin sensitivity:

Resveratrol retards progression of diabetic nephropathy through modulations of oxidative stress, proinflammatory cytokines, and AMP-activated protein kinase

It has neuroprotective effects too:

Resveratrol promotes clearance of Alzheimer’s disease amyloid-beta peptides

Is it safe?

For most people, it is generally recognized as safe. However, if you are on blood-thinners or otherwise have a bleeding disorder, you might want to skip it:

Antiplatelet activity of synthetic and natural resveratrol in red wine

You also might want to check with your pharmacist/doctor, if you’re on blood pressure meds, anxiety meds, or immunosuppressants, as it can increase the amount of these drugs that will then stay in your system:

Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study

And as ever, of course, if unsure just check with your pharmacist/doctor, to be on the safe side.

Where to get it?

We don’t sell it, but here’s an example product on Amazon for your convenience

Enjoy!

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  • It’s Not You, It’s Your Hormones – by Nicki Williams, DipION, mBANT, CNHC

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    So, first a quick note: this book is very similar to the popular bestseller “The Galveston Diet”, not just in content, but all the way down to its formatting. Some Amazon reviewers have even gone so far as to suggest that “It’s Not You, It’s Your Hormones” (2017) brazenly plagiarized “The Galveston Diet” (2023). However, after carefully examining the publication dates, we feel quite confident that this book is not a copy of the one that came out six years after it. As such, we’ve opted for reviewing the original book.

    Nicki Williams’ basic principle is that we can manage our hormonal fluctuations, by managing our diet. Specifically, in three main ways:

    • Intermittent fasting
    • Anti-inflammatory diet
    • Eating more protein and healthy fats

    Why should these things matter to our hormones? The answer is to remember that our hormones aren’t just the sex hormones. We have hormones for hunger and satedness, hormones for stress and relaxation, hormones for blood sugar regulation, hormones for sleep and wakefulness, and more. These many hormones make up our endocrine system, and affecting one part of it will affect the others.

    Will these things magically undo the effects of the menopause? Well, some things yes, other things no. No diet can do the job of HRT. But by tweaking endocrine system inputs, we can tweak endocrine system outputs, and that’s what this book is for.

    The style is very accessible and clear, and Williams walks us through the changes we may want to make, to avoid the changes we don’t want.

    Bottom line: this book is aimed at peri-menopausal and post-menopausal women. It could also definitely help a lot of people with PCOS too, and, when it comes down it it, pretty much anyone with an endocrine system. It’s a well-evidenced, well-established, healthy way of eating regardless of age, sex, or (most) physical conditions.

    Click here to check out It’s Not You, It’s Your Hormones, and take control of yours!

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  • Cold Medicines & Heart Health

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Cold Medicines & Heart Health

    In the wake of many decongestants disappearing from a lot of shelves after a common active ingredient being declared useless*, you may find yourself considering alternative decongestants at this time of year.

    *In case you missed it:

    Why Is Oral Phenylephrine on the Market After Compelling Evidence of Its Ineffectiveness as a Decongestant?

    It doesn’t seem to be dangerous, by the way, just also not effective:

    FDA Panel Says Common OTC Decongestant, Phenylephrine, Is Useless

    Good for your nose, bad for your heart?

    With products based on phenylephrine out of the running, products based on pseudoephedrine, a competing drug, are enjoying a surge in popularity.

    Good news: pseudoephedrine works!

    Bad news: pseudoephedrine works because it is a vasoconstrictor, and that vasoconstriction reduces nasal swelling. That same vasoconstriction also raises overall blood pressure, potentially dangerously, depending on an assortment of other conditions you might have.

    Further reading: Can decongestants spike your blood pressure? What to know about hypertension and cold medicine

    Who’s at risk?

    The warning label, unread by many, reads:

    ❝Do not use this product if you have heart disease, high blood pressure, thyroid disease, diabetes, or difficulty in urination due to enlargement of the prostate gland, unless directed by a doctor❞

    Source: Harvard Health | Don’t let decongestants squeeze your heart

    What are the other options?

    The same source as above recommends antihistamines as an option to be considered, citing:

    ❝Antihistamines such as […] cetirizine (Zyrtec) and loratadine (Claritin) can help with a stuffy nose and are safe for the heart.❞

    But we’d be remiss not to mention drug-free options too, for example:

    • Saline rinse with a neti pot or similar
    • Use of a humidifier in your house/room
    • Steam inhalation, with or without eucalyptus etc

    See also: Inhaled Eucalyptus’s Immunomodulatory and Antimicrobial Effects

    Take care!

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  • Nudge – by Richard Thaler & Cass Sunstein

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    How often in life do we make a suboptimal decision that ends up plaguing us for a long time afterwards? Sometimes, a single good or bad decision can even directly change the rest of our life.

    So, it really is important that we try to optimize the decisions we do make.

    Professors Richard Thaler and Cass Sunstein look at all kinds of decision-making in this book. Their goal, as per the subtitle, is “improving decisions about health, wealth, and happiness”.

    For the most part, the book concentrates on “nudges”. Small factors that influence our decisions one way or another.

    Most importantly: that some of them are very good reasons to be nudged; others, very bad ones. And they often look similar.

    Where this book excels is in highlighting the many ways we make decisions without even thinking about it… or we think about it, but only down a prescribed, foreseen track, to an externally expected conclusion (for example, an insurance company offering three packages, but two of them exist only to direct you to the “correct” choice).

    A weakness of the book is that in some aspects it’s a little inconsistent. The authors describe their economic philosophy as “libertarian paternalism”, and as libertarians they’re against mandates, except when as paternalists they’re for them. But, if we take away their labels, this boils down to “some mandates can be good and some can be bad”, which would not be so inconsistent after all.

    Bottom line: if you’d like to better understand your own decision-making processes through the eyes of policy-setting economists (especially Sunstein, who worked for the White House Office of Information & Regulatory Affairs) whose job it is to make sure you make the “right” decisions, then this is a very enlightening book.

    Click here to check out Nudge and improve your decision-making clarity!

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    We’ve reviewed intermittent fasting books before, so what makes this one different?

    The title “Fast. Feast. Repeat.” doesn’t give much away; after all, we already know that that’s what intermittent fasting is.

    After taking the reader though the basics of how intermittent fasting works and what it does for the body, much of the rest of the book is given over to improvements.

    That’s what the real strength of this book is: ways to make intermittent fasting more efficient, including how to avoid plateaus. After all, sometimes it can seem like the only way to push further with intermittent fasting is to restrict the eating window further. Not so!

    Instead, Dr. Stephens gives us ways to keep confusing our metabolism (in a good way) if, for example, we had a weight loss goal we haven’t met yet.

    Best of all, this comes without actually having to eat less.

    Bottom line: if you want to be in good physical health, and/but also believe that life is for living and you enjoy eating food, then this book can resolve that age-old dilemma!

    Click here to check out Fast. Feast. Repeat., and supercharge your health without sacrificing happiness!

    Don’t Forget…

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  • Sun, Sea, And Sudden Killers To Avoid

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    Stay Safe From Heat Exhaustion & Heatstroke!

    For most of us, summer is upon us now. Which can be lovely… and also bring new, different health risks. Today we’re going to talk about heat exhaustion and heatstroke.

    What’s the difference?

    Heat exhaustion is a milder form of heatstroke, but the former can turn into the latter very quickly if left untreated.

    Symptoms of heat exhaustion include:

    • Headache
    • Nausea
    • Cold sweats
    • Light-headedness

    Symptoms of heatstroke include the above and also:

    • Red/flushed-looking skin
    • High body temperature (104ºF / 40ºC)
    • Disorientation/confusion
    • Accelerated heart rate

    Click here for a handy downloadable infographic you can keep on your phone

    What should we do about it?

    In the case of heatstroke, call 911 or the equivalent emergency number for the country where you are.

    Hopefully we can avoid it getting that far, though:

    Prevention first

    Here are some top tips to avoid heat exhaustion and thus also avoid heatstroke. Many are common sense, but it’s easy to forget things—especially in the moment, on a hot sunny day!

    • Hydrate, hydrate, hydrate
      • (Non-sugary) iced teas, fruit infusions, that sort of thing are more hydrating than water alone
      • Avoid alcohol
        • If you really want to imbibe, rehydrate between each alcoholic drink
    • Time your exercise with the heat in mind
      • In other words, make any exercise session early or late in the day, not during the hottest period
    • Use sunscreen
      • This isn’t just for skin health (though it is important for that); it will also help keep you cooler, as it blocks the UV rays that literally cook your cells
    • Keep your environment cool
      • Shade is good, air conditioning / cooling fans can help.
      • A wide-brimmed hat is portable shade just for you
    • Wear loose, breathable clothing
      • We write about health, not fashion, but: light breathable clothes that cover more of your body are generally better healthwise in this context, than minimal clothes that don’t, if you’re in the sun.
    • Be aware of any medications you’re taking that will increase your sensitivity to heat.
      • This includes medications that are dehydrating, and includes most anti-depressants, many anti-nausea medications, some anti-allergy medications, and more.
      • Check your labels/leaflets, look up your meds online, or ask your pharmacist.

    Treatment

    If prevention fails, treatment is next. Again, in the case of heatstroke, it’s time for an ambulance.

    If symptoms are “only” of heat exhaustion and are more mild, then:

    • Move to a cooler location
    • Rehydrate again
    • Remove clothing that’s confining or too thick
      • What does confining mean? Clothing that’s tight and may interfere with the body’s ability to lose heat.
        • For example, you might want to lose your sports bra, but there is no need to lose a bikini, for instance.
    • Use ice packs or towels soaked in cold water, applied to your body, especially wear circulation is easiest to affect, e.g. forehead, wrists, back of neck, under the arms, or groin.
    • A cool bath or shower, or a dip in the pool may help cool you down, but only do this if there’s someone else around and you’re not too dizzy.
      • This isn’t a good moment to go in the sea, no matter how refreshing it would be. You do not want to avoid heatstroke by drowning instead.

    If full recovery doesn’t occur within a couple of hours, seek medical help.

    Stay safe and have fun!

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  • Makkō-Hō – by Haruka Nagai

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    We’ve all heard the claims, “Fluent in 3 Months!”, “Russian in Two Weeks!”, “Overnight Mandarin Chinese”, “15-Minute Arabic!”, “Instant Italian!”.

    We see the same in the world of health and fitness too. So how does this one’s claim of “five minutes’ physical fitness” hold up?

    Well, it is 5 minutes per day. And indeed, the author writes:

    ❝The total time [to do these exercises], then, is only one minute and thirty seconds. This series I call one round. When it has been completed, execute another complete round. You should find the exercises easier to do the second time. Executed this way, the exercsies will prove very effective, though they take only three minutes in all. After you have leaned back into the final position, you must remain in that posture for one minute. That brings the total time to four minutes. Even when [some small additions] are added, it takes only five minutes at most.❞

    The exercises themselves are from makkō-hō, which is a kind of Japanese dynamic yoga. They involve repetitions of (mostly) moving stretches with good form, and are excellent for mobility and general health, keeping us supple and robust as we get older.

    The text descriptions are clear, as are the diagrams and photos. The language is a little dated, as this book was written in the 1970s, but the techniques themselves are timeless.

    Bottom line: consider it a 5-minute anti-aging regimen. And, as Nagai says, “the person who cannot find 5 minutes out of 24 hours, was never truly interested in their health”.

    Click here to check out Makkō-Hō and schedule your five minutes!

    Don’t Forget…

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