Red Light, Go!

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Casting Yourself In A Healthier Light

In Tuesday’s newsletter, we asked you for your opinion of red light therapy (henceforth: RLT), and got the above-depicted, below-described, set of responses:

  • About 51% said “I have no idea whether light therapy works or not”
  • About 24% said “Red light therapy is a valuable skin rejuvenation therapy”
  • About 23% said “I have not previously heard of red light therapy”
  • One (1) person said: “Red light therapy is a scam to sell shiny gadgets”

A number of subscribers wrote with personal anecdotes of using red light therapy to beneficial effect, for example:

❝My husband used red light therapy after surgery on his hand. It did seem to speed healing of the incision and there is very minimal scarring. I would like to know if the red light really helped or if he was just lucky❞

~ 10almonds subscriber

And one wrote to report having observed mixed results amongst friends, per:

❝Some people it works, others I’ve seen it breaks them out❞

~ 10almonds subscriber

So, what does the science say?

RLT rejuvenates skin, insofar as it reduces wrinkles and fine lines: True or False?

True! This one’s pretty clear-cut, so we’ll just give one example study of many, which found:

❝The treated subjects experienced significantly improved skin complexion and skin feeling, profilometrically assessed skin roughness, and ultrasonographically measured collagen density.

The blinded clinical evaluation of photographs confirmed significant improvement in the intervention groups compared with the control❞

~ Dr. Alexander Wunsch & Dr. Karsten Matuschka

Read in full: A Controlled Trial to Determine the Efficacy of Red and Near-Infrared Light Treatment in Patient Satisfaction, Reduction of Fine Lines, Wrinkles, Skin Roughness, and Intradermal Collagen Density Increase

RLT helps speed up healing of wounds: True or False?

True! There is less science for this than the above claim, but the studies that have been done are quite compelling, for example this NASA technology study found that…

❝LED produced improvement of greater than 40% in musculoskeletal training injuries in Navy SEAL team members, and decreased wound healing time in crew members aboard a U.S. Naval submarine.❞

~ Dr. Harry Whelan et al.

Read more: Effect of NASA light-emitting diode irradiation on wound healing

RLT’s benefits are only skin-deep: True or False?

False, probably, but we’d love to see more science for this, to be sure.

However, it does look like wavelengths in the near-infrared spectrum reduce the abnormal tau protein and neurofibrillary tangles associated with Alzheimer’s disease, resulting in increased blood flow to the brain, and a decrease in neuroinflammation:

Therapeutic Potential of Photobiomodulation In Alzheimer’s Disease: A Systematic Review

Would you like to try RLT for yourself?

There are some contraindications, for example:

  • if you have photosensitivity (for obvious reasons)
  • if you have Lupus (mostly because of the above)
  • if you have hyperthyroidism (because if you use RLT to your neck as well as face, it may help stimulate thyroid function, which in your case is not what you want)

As ever, please check with your own doctor if you’re not completely sure; we can’t cover all bases here, and cannot speak for your individual circumstances.

For most people though, it’s very safe, and if you’d like to try it, here’s an example product on Amazon, and by all means do read reviews and shop around for the ideal device for you

Take care! 😎

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  • Ginger Does A Lot More Than You Think

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    Ginger’s benefits go deep!

    You are doubtlessly already familiar with what ginger is, so let’s skip right into the science.

    The most relevant active compound in the ginger root is called gingerol, and people enjoy it not just for its taste, but also a stack of health reasons, such as:

    • For weight loss
    • Against nausea
    • Against inflammation
    • For cardiovascular health
    • Against neurodegeneration

    Quite a collection! So, what does the science say?

    For weight loss

    This one’s quite straightforward. It not only helps overall weight loss, but also specifically improves waist-hip ratio, which is a much more important indicator of health than BMI.

    Read: The effects of ginger intake on weight loss and metabolic profiles among overweight and obese subjects: a systematic review and meta-analysis of randomized controlled trials

    Against nausea & pain

    Ginger has proven its effectiveness in many high quality clinical trials, against general nausea, post-surgery nausea, chemotherapy-induced nausea, and pregnancy-related nausea.

    Source: Ginger on Human Health: A Comprehensive Systematic Review of 109 Randomized Controlled Trials

    However! While it very clearly has been shown to be beneficial in the majority of cases, there are some small studies that suggest it may not be safe to take close to the time of giving birth, or in people with a history of pregnancy loss, or unusual vaginal bleeding, or clotting disorders.

    See specifically: Ginger for nausea and vomiting of pregnancy

    As a side note on the topic of “trouble down there”, ginger has also been found to be as effective as Novafen (a combination drug of acetaminophen (Tylenol), caffeine, and ibuprofen), in the task of relieving menstrual pain:

    See: Effect of Ginger and Novafen on menstrual pain: A cross-over trial

    Against inflammation & pain

    Ginger has well-established anti-inflammatory (and, incidentally, which affects many of the same systems, antioxidant) effects. Let’s take a look at that first:

    Read: Effect of Ginger on Inflammatory Diseases

    Attentive readers will note that this means that ginger is not merely some nebulous anti-inflammatory agent. Rather, it also specifically helps alleviate delineable inflammatory diseases, ranging from colitis to Crohn’s, arthritis to lupus.

    We’ll be honest (we always are!), the benefits in this case are not necessarily life-changing, but they are a statistically significant improvement, and if you are living with one of those conditions, chances are you’ll be glad of even things described in scientific literature as “modestly efficacious”.

    What does “modestly efficacious” look like? Here are the numbers from a review of 593 patients’ results in clinical trials (against placebo):

    ❝Following ginger intake, a statistically significant pain reduction SMD = −0.30 ([95% CI: [(−0.50, −0.09)], P = 0.005]) with a low degree of inconsistency among trials (I2 = 27%), and a statistically significant reduction in disability SMD = −0.22 ([95% CI: ([−0.39, −0.04)]; P = 0.01; I2 = 0%]) were seen, both in favor of ginger.❞

    ~ Bartels et al.

    To de-mathify that:

    • Ginger reduced pain by 30%
    • Ginger reduced disability by 22%

    Read the source: Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trials

    Because (in part) of the same signalling pathways, it also has benefits against cancer (and you’ll remember, it also reduces the symptoms of chemotherapy).

    See for example: Ginger’s Role in Prevention and Treatment of Gastrointestinal Cancer

    For cardiovascular health

    In this case, its benefits are mostly twofold:

    Against neurodegeneration

    This is in large part because it reduces inflammation, which we discussed earlier.

    But, not everything passes the blood-brain barrier, so it’s worth noting when something (like gingerol) does also have an effect on brain health as well as the rest of the body.

    You do not want inflammation in your brain; that is Bad™ and strongly associated with Alzheimer’s and Parkinson’s.

    As well as reducing neuroinflammation, ginger has other relevant mechanisms too:

    ❝Its bioactive compounds may improve neurological symptoms and pathological conditions by modulating cell death or cell survival signaling molecules.

    The cognitive enhancing effects of ginger might be partly explained via alteration of both the monoamine and the cholinergic systems in various brain areas.

    Moreover, ginger decreases the production of inflammatory related factors❞

    ~ Arcusa et al.

    Check it out in full, as this is quite interesting:

    Role of Ginger in the Prevention of Neurodegenerative Diseases

    How much to take?

    In most studies, doses of 1–3 grams/day were used.

    Where to get it?

    Your local supermarket, as a first port-of-call. Especially given the dose you want, it may be nicer for you to have a touch of sliced ginger root in your cooking, rather than taking 2–6 capsules per day to get the same dose.

    Obviously, this depends on your culinary preferences, and ginger certainly doesn’t go with everything!

    If you do want it as a supplement, here is an example product on Amazon, for your convenience.

    Enjoy!

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  • The Meds That Impair Decision-Making

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Impairment to cognitive function is often comorbid with Parkinson’s disease. That is to say: it’s not a symptom of Parkinson’s, but it often occurs in the same people. This may seem natural: after all, both are strongly associated with aging.

    However, recent (last month, at time of writing) research has brought to light a very specific way in which medication for Parkinson’s may impair the ability to make sound decisions.

    Obviously, this is a big deal, because it can affect healthcare decisions, financial decisions, and more—greatly impacting quality of life.

    See also: Age-related differences in financial decision-making and social influence

    (in which older people were found more likely to be influenced by the impulsive financial preferences of others than their younger counterparts, when other factors are controlled for)

    As for how this pans out when it comes to Parkinson’s meds…

    Pramipexole (PPX)

    This drug can, due to an overlap in molecular shape, mimic dopamine in the brains of people who don’t have enough—such as those with Parkinson’s disease. This (as you might expect) helps alleviate Parkinson’s symptoms.

    However, researchers found that mice treated with PPX and given a touch-screen based gambling game picked the high-risk, high reward option much more often. In the hopes of winning strawberry milkshake (the reward), they got themselves subjected to a lot of blindingly-bright flashing lights (the risk, to which untreated mice were much more averse, as this is very stressful for a mouse).

    You may be wondering: did the mice have Parkinson’s?

    The answer: kind of; they had been subjected to injections with 6-hydroxydopamine, which damages dopamine-producing neurons similarly to Parkinson’s.

    This result was somewhat surprising, because one would expect that a mouse whose depleted dopamine was being mimicked by a stand-in (thus, doing much of the job of dopamine) would be less swayed by the allure of gambling (a high-dopamine activity), since gambling is typically most attractive to those who are desperate to find a crumb of dopamine somewhere.

    They did find out why this happened, by the way, the PPX hyperactivated the external globus pallidus (also called GPe, and notwithstanding the name, this is located deep inside the brain). Chemically inhibiting this area of the brain reduced the risk-taking activity of the mice.

    This has important implications for Parkinson’s patients, because:

    • on an individual level, it means this is a side effect of PPX to be aware of
    • on a research-and-development level, it means drugs need to be developed that specifically target the GPe, to avoid/mitigate this side effect.

    You can read the study in full here:

    Pramipexole Hyperactivates the External Globus Pallidus and Impairs Decision-Making in a Mouse Model of Parkinson’s Disease

    Don’t want to get Parkinson’s in the first place?

    While nothing is a magic bullet, there are things that can greatly increase or decrease Parkinson’s risk. Here’s a big one, as found recently (last week, at the time of writing):

    Air Pollution and Parkinson’s Disease in a Population-Based Study

    Also: knowing about its onset sooner rather than later is scary, but beneficial. So, with that in mind…

    Recognize The Early Symptoms Of Parkinson’s Disease

    Finally, because Parkinson’s disease is theorized to be caused by a dysfunction of alpha-synuclein clearance (much like the dysfunction of beta-amyloid clearance, in the case of Alzheimer’s disease), this means that having a healthy glymphatic system (glial cells doing the same clean-up job as the lymphatic system, but in the brain) is critical:

    How To Clean Your Brain (Glymphatic Health Primer)

    Take care!

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  • Menopause: 50 Things You Need to Know – by Dr. Felice Gersh

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Can you list 50 important facts about the menopause? If not, you’ll surely find things to learn in here.

    The book is divided into three main sections:

    1. What to expect in perimenopause
    2. What to expect in early menopause
    3. What to expect in late menopause

    Each section comes with an alarming array of symptoms, ranging from perimenopause fatigue and acne to late menopause tooth loss and vaginal prolapse. This is not to say that everyone will experience everything (fortunately), but rather, that these are the things that can happen and should not arrive unexpected.

    Helpfully, of course, Dr. Gersh also gives advice on how to improve your energy and skin health, as well as keep your teeth and vagina in place. And similar professional insights for the rest of the “50 things you need to know”.

    The style is like one big (182 pages) patient information leaflet—thus, very clear, explaining everything, and offering reassurance where possible and also what things are reasonable cause for seeking personalized medical attention.

    Bottom line: if menopause is in your future, present, or very near past, this is an excellent book for you.

    Click here to check out Menopause: 50 Things You Need To Know, and know them!

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  • Metabolism Made Simple – by Sam Miller

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    The author, a nutritionist, sets out to present exactly what the title promises: metabolism made simple.

    On this, he delivers. Explaining things from the most basic elements upwards, he gives a well-rounded introduction to the science of metabolism and what it means for us when it comes to our dietary habits.

    The book is in large part a how-to, but with a lot of flexibility left to the reader. He doesn’t advocate for any particular dietary plan, but he does give the reader the tools necessary to make an informed choice and go from there—including the pros and cons of some popular dietary approaches.

    He talks a lot about getting the most out of whatever we do choose to—managing appetite, mitigating adaptation, maximizing adherence, optimizing absorption of nutrients, and so forth.

    The book does also touch on things like exercise and stress management, but diet is always center-stage and is the main topic of the book.

    The style is—as promised by the title—simple. However, this simply means that he avoids unnecessary jargon and explains any necessary terms along the way. As for backing up claims with science, there are 22 pages of references, which is always a good sign.

    Bottom line: if you’d like a simple, practical guide to eating for metabolic health, this book will start you off on a good footing.

    Click here to check out Metabolism Made Simple, and give your metabolic health a boost!

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  • Half Of Americans Over 50 Have Hemorrhoids, But They Can Be Prevented!

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s Q&A Day at 10almonds!

    Have a question or a request? We love to hear from you!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    ❝Hello. I was hoping you could give some useful tips about how to avoid a painful ailment that has affected Ernest Hemingway, Karl Marx, David Livingstone, Napoleon, Marilyn Monroe, King Alfred, and Martin Luther, and, I confess, me from time to time … namely, hemorrhoids. Help!❞

    Firstly: that list could be a lot longer! We don’t have global stats, but in the US for example, half of adults over 50 have hemorrhoids.

    So, you’re certainly not alone. People just don’t talk about it.

    But, there are preventative things you can do:

    Fiber, fiber, fiber. See also:

    Level-Up Your Fiber Intake! (Without Difficulty Or Discomfort)

    Hydrate, hydrate, hydrate.

    This one’s simple enough. If you are dehydrated, constipation is more likely, and with it, hemorrhoids.

    Watch your meds…

    Some medications can cause constipation—painkillers containing codeine are a common culprit, for example.

    When you go, go!

    Not only can prolonged straining promote hemorrhoids, but also (if you’ll pardon the phrasing—there’s only so delicately we can say this) simply sitting with things partway “open” down there is not good for its health; things can quickly become irritated, and that can lead to hemorrhoids.

    So: when you go, go. Leave your phone in another room!

    Wash—but carefully.

    Beyond your normal showering/bathing routine, a bidet is a great option for keeping things happy down there, if you have that option available to you.

    However, if you have hemorrhoids, don’t use soap, as this can cause irritation and make it worse.

    Warm water is fine, as is a salt bath, and pat dry and/or use gentle wet-wipes rather than rougher paper.

    You can follow up with a hemorrhoid cream of your choice (or hydrocortisone, unless that’s contraindicated by another condition you have)

    Know when to seek help

    Hemorrhoids will usually go away by themselves if not exacerbated. But if it’s getting unduly difficult, and/or you’re bleeding down there, it’s time to see a doctor.

    Note on bleeding: even if you’re 100% sure you have hemorrhoids, there are still other reasons you could be bleeding, and so it needs checking out.

    Hemorrhoid treatment, if needed, will vary depending on severity. Beyond creams and lotions, there are other options that are less fun but sometimes necessary, including injections, electrotherapy, banding, or surgery.

    Take care!

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  • Ideal Blood Pressure Numbers Explained

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s Q&A Day at 10almonds!

    Have a question or a request? You can always hit “reply” to any of our emails, or use the feedback widget at the bottom!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    ❝Maybe I missed it but the study on blood pressure did it say what the 2 numbers should read ideally?❞

    We linked it at the top of the article rather than including it inline, as we were short on space (and there was a chart rather than a “these two numbers” quick answer), but we have a little more space today, so:

    CategorySystolic (mm Hg)Diastolic (mm Hg)
    Normal< 120AND< 80
    Elevated120 – 129AND< 80
    Stage 1 – High Blood Pressure130 – 139OR80 – 89
    Stage 2 – High Blood Pressure140 or higherOR90 or higher
    Hypertensive CrisisAbove 180AND/ORAbove 120

    To oversimplify for a “these two numbers” answer, under 120/80 is generally considered good, unless it is under 90/60, in which case that becomes hypotension.

    Hypotension, the blood pressure being too low, means your organs may not get enough oxygen and if they don’t, they will start shutting down.

    To give you an idea how serious this, this is the closed-circuit equivalent of the hypovolemic shock that occurs when someone is bleeding out onto the floor. Technically, bleeding to death also results in low blood pressure, of course, hence the similarity.

    So: just a little under 120/80 is great.

    Don’t Forget…

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