Hair-Loss Remedies, By Science

10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

10almonds Gets Hairy

Hair loss is a thing that at some point affects most men and a large minority of women. It can be a source of considerable dysphoria for both, as it’s often seen as a loss of virility/femininity respectively, and is societally stigmatized in various ways.

Today we’re going to focus on the most common kind: androgenic alopecia, which is called “male pattern baldness” in men and “female pattern baldness” in women, despite being the same thing.

We won’t spend a lot of time on the science of why this happens (we’re going to focus on the remedies instead), but suffice it to say that genes and hormones both play a role, with dihydrogen testosterone (DHT) being the primary villain in this case.

We’ve talked before about the science of 5α-reductase inhibitors to block the conversion of regular testosterone* to DHT, its more potent form:

One Man’s Saw Palmetto Is Another Woman’s Serenoa Repens…

*We all make this to a greater or lesser degree, unless we have had our ovaries/testes removed.

Finasteride

Finasteride is a 5α-reductase inhibitor that performs similarly to saw palmetto, but comes in tiny pills instead of needing to take a much higher dose of supplement (5mg of finasteride is comparable in efficacy to a little over 300mg of saw palmetto).

Does it work? Yes!

Any drawbacks? A few:

  • It’ll take 3–6 months to start seeing effects. This is because of the hormonal life-cycle of human hairs.
  • Common side-effects include ED.
  • It is popularly labelled/prescribed as “only for men

On that latter point: the warnings about this are severe, detailing how women must not take it, must not even touch it if it has been cut up or crushed.

However… That’s because it can carry a big risk to our unborn fetuses. So, if we are confident we definitely don’t have one of those, it’s not actually applicable to us.

That said, finasteride’s results in women aren’t nearly so clear-cut as in men (though also, there has been less research, largely because of the above). Here’s an interesting breakdown in more words than we have room for here:

Finasteride for Women: Everything You Need to Know

Spironolactone

This one’s generally prescribed to women, not men, largely because it’s the drug sometimes popularly known as a “chemical castration” drug, which isn’t typically great marketing for men (although it can be applied topically, which will have less of an effect on the rest of the body). For women, this risk is simply not an issue.

We’ll be brief on this one, but we’ll just drop this, so that you know it’s an option that works:

Spironolactone is an effective and safe treatment of androgenic alopecia which can enhance the efficacy when combined with other conventional treatments such as minoxidil.

Topical spironolactone is safer than oral administration and is suitable for both male and female patients, and is expected to become a common drug for those who do not have a good response to minoxidil❞

Read more: The Efficacy and Safety of Oral and Topical Spironolactone in Androgenetic Alopecia Treatment: A Systematic Review

Minoxidil

This one is available (to men and women) without prescription. It’s applied topically, and works by shortcutting the hair’s hormonal growth cycle, to reduce the resting phase and kick it into a growth phase.

Does it work? Yes!

Any drawbacks? A few:

  • Whereas you’ll remember finasteride takes 3–6 months to see any effect, this one will have an effect very quickly
    • Specifically, the immediate effect is: your rate of hair loss will appear to dramatically speed up
    • This happens because when hairs are kicked into their growth phase if they were in a resting phase, the first part of that growth phase is to shed each old hair to make room for the new one
  • You’ll then need the same 3–6 months as with finasteride, to see the regrowth effects
  • If you stop using it, you will immediately shed whatever hair you gained by this method

Why do people choose this over finasteride? For one of three reasons, mainly:

  • They are women, and not offered finasteride
  • They are men, and do not want the side effects of finasteride
  • They just saw an ad and tried it

As to how it works:

Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells

Some final notes:

There are some other contraindications and warnings with each of these drugs by the way, so do speak with your doctor/pharmacist. For example:

There are other hair loss remedies and practices, but the above three are the heavy-hitters, so that’s what we spent our time/space on today. We’ll perhaps cover the less powerful (but less risky) options one of these days.

Meanwhile, take care!

Don’t Forget…

Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

Recommended

  • How Too Much Salt May Lead To Organ Failure
  • Jackfruit vs Durian – Which is Healthier?
    Durian trumps jackfruit with more fiber, B-vitamins, and minerals, despite its devilish appearance and notorious smell! Just don’t mix with alcohol.

Learn to Age Gracefully

Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:

  • Time Smart – by Dr. Ashley Whillans

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    First, what this is not: it’s not a productivity book.

    What is rather: a book of better wellbeing.

    There is a little overlap, insofar as getting “time smart” in the ways that Dr. Whillans recommends will give you more ability to also be more productive—if that’s what you want.

    She talks us through time traps and the “time poverty epidemic”, as well as steps to finding time and funding time. Perhaps most critical idea-wise is the chapter on building a “time-affluence habit”, making decisions that prioritize your time-freedom where you can—which in turn will allow you to build yet more. Kind of like compound interest really, but for time.

    The writing style is a conversational tone, but peppered with bullet-point lists and charts and the like from time to time, and often with citations to back up claims. It makes for a very readable book, and yet one that’s also inspiring of the confidence that it’s more than just one person’s opinion.

    Bottom line: if you sometimes feel like you could do everything you want to if you could just find the time, this book can help you get there.

    Click here to check out Time Smart, and live your most satisfying life!

    Share This Post

  • 7 Essential Devices For Hand Arthritis: Regain Control of Your Life

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Dr. Diana Girnita is a double board-certified physician in rheumatology and internal medicine. With a PhD in immunology (on top of her MD), and training at Harvard and top universities, she founded Rheumatologist OnCall, offering integrative medicine to broaden rheumatology access. Here’s what she has to say about things that make life easier:

    Get your hands on these…

    The seven devices that Dr. Girnita recommends are:

    • Hand grip strengthener: helps build grip strength with a spring-loaded mechanism. Regular use can improve strength and reduce pain.
    • Finger exerciser: different device; similar principle: it strengthens hand and finger muscles using resistance, enhancing hand function.
    • Moisturizing paraffin bath: a heated paraffin wax bath that soothes hands, providing heat therapy and moisturizing the skin.
    • Weighted silverware: weighted utensils (knives, forks, spoons) make gripping easier and provide stability for eating.
    • Foam tubing grips: foam covers to make kitchen tools, toothbrushes, and hairbrushes easier to grip.
    • Electric can-opener: reduces strain in opening cans, making meal preparation more accessible.
    • Compression gloves: provide gentle compression to reduce swelling and pain, improving hand flexibility and circulation.
    • Door knob cover grips: make it easier to turn doorknobs by providing a larger surface to grip.
    • Wider-grip pens: ergonomically designed pens with a larger diameter and softer grip reduce hand strain while writing.

    This writer, who does not have arthritis but also does not have anything like the grip strength she used to, also recommends a jar opener like this one.

    As a bonus, if you spend a lot of time writing at a computer, an ergonomic split keyboard like this one goes a long way to avoiding carpal tunnel syndrome, and logically must be better for arthritis than a regular keyboard; another excellent thing to have (that again this writer uses and swears by) is an ergonomic vertical mouse like this one (aligns the wrist bones correctly; the “normal” horizontal version is woeful for the carpal bones). These things are both also excellent to help avoid worsening peripheral neuropathy (something that troubles this writer’s wrists if she’s not careful, due to old injuries there).

    For more on the seven things otherwise listed above, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like to read:

    Take care!

    Share This Post

  • Asparagus vs Eggplant – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing asparagus to eggplant, we picked the asparagus.

    Why?

    In terms of macros, they’re very similar. Technically asparagus has twice the protein, but it’s at 2.2g/100g compared to eggplant’s 0.98g/100g, so it’s not too meaningful. They’re both mostly water, low in carbs, with a little fiber, and negligible fat (though eggplant technically has more fat, but again, these numbers are miniscule). For practical purposes, the two vegetables are even in this category, or if you really want decisive answers, a tiny margin of a win for asparagus.

    In the category of vitamins, asparagus is much higher in vitamins A, B1, B2, B3, B5, B6, B9, E, & K, as well as choline. Eggplant is not higher in any vitamins. A clear win for asparagus.

    When it comes to minerals, asparagus is much higher in calcium, copper, iron, phosphorus, selenium, and zinc, while eggplant is a little higher in manganese. Another easy win for asparagus.

    Lastly, asparagus wins on polyphenols too, with its high quercetin content. Eggplant does contain some polyphenols, but in such tiny amounts that even added up they’re less than 7% of what asparagus has to offer in quercetin alone.

    Obviously, enjoy both, though! Diversity is healthy.

    Want to learn more?

    You might like to read:

    Fight Inflammation & Protect Your Brain, With Quercetin

    Take care!

    Share This Post

Related Posts

  • How Too Much Salt May Lead To Organ Failure
  • Young Forever – by Dr. Mark Hyman

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    A lot of work on the topic of aging looks at dealing with symptoms of aging, rather than the causes. And, that’s worthy too! Those symptoms often do need addressing. But this book is about treating the causes.

    Dr. Hyman outlines:

    • How and why we age
    • The root causes of aging
    • The ten hallmarks of aging

    From there, we go on to learn about the foundations of longevity, and balancing our seven core biological systems:

    1. Nutrition, digestion, and the microbiome
    2. Immune and inflammatory system
    3. Cellular energy
    4. Biotransformation and elimination/detoxification*
    5. Hormones, neurotransmitters, and other signalling molecules
    6. Circulation and lymphatic flow
    7. Structural health, from muscle and bones to cells and tissues

    *This isn’t about celery juice fasts and the like; this talking about the work your kidneys, liver, and other organs do

    The book goes on to detail how, precisely, with practical actionable advices, to optimize and take care of each of those systems.

    All in all: if you want a great foundational understanding of aging and how to slow it to increase your healthy lifespan, this is a very respectable option.

    Click here to get your copy of “Young Forever” from Amazon today!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:

  • Delicious Daily Daal

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    You’re not obliged to eat this every day, but you might want to. The reason we called this one this, is because it’s a super simple recipe (don’t be put off by the long ingredients list; it’s mostly spices making it look long) which, after you’ve done it a couple of times, you could practically do it in your sleep quickly and easily.

    The name “lentil daal” is a bit like “naan bread”—a redundant tautology repeated more than once unnecessarily, but it helps for international clarity. The dish is usually served with naan, by the way, and rice. We don’t have room for those today, maybe we’ll do them another day; for now, you can just cook rice how you normally do, and buy naan if necessary.

    Writer’s note: I love strong flavors; many people don’t. For this reason I’m going to give a “basic” version. Please feel free to multiply the spices if you feel so inclined. Where I give “one teaspoon” of a spice below, I’d use a tablespoon at home. Chili peppers can vary in heat a lot even within the same type, so what I do for any given batch is taste one (raw), judge the heat, and use an appropriate number of peppers accordingly. If you don’t want to do that, I suggest just guessing low (as per the instructions below) and if you find at the end you want more heat, you can always stir in a little hot sauce. I know that sounds heretical, but at the end of the day, the primary goal of cooking is to have the meal you want at the end of it.

    You will need

    • 1 1/2 cups red lentils
    • 1 large onion, chopped
    • 1 large bulb garlic, minced
    • 1 oz ginger, grated
    • 2 hot peppers (e.g. serrano), chopped
    • 1 tsp ground cumin
    • 1 tsp ground coriander
    • 1 tsp ground turmeric
    • 1 tsp garam masala (this is also ground, but it doesn’t come any other way)
    • 1 tsp chili flakes (omit if you’re not a fan of heat)
    • 2 tsp cracked black pepper
    • 1 tsp salt ← I wouldn’t recommend multiplying this one unless later, to taste. In fact, instead of 1 tsp salt I use 2 tsp MSG, which has less sodium than 1 tsp salt. But “1 tsp salt” is the “easy to find in the store” version.
    • 2 large or 3 small tomatoes, chopped (or 1 can chopped tomatoes)
    • 2 shallots, thinly sliced
    • 1 tsp cumin seeds
    • 1 tsp mustard seeds
    • 1 tsp coriander seeds
    • 1 tsp black peppercorns
    • 1 lime
    • 1/2 cup fresh cilantro, or if you have the “that tastes like soap” gene, parsley, chopped
    • Coconut oil for cooking (if you don’t like coconut, consider springing for avocado oil—if you use olive oil, it’ll add an olivey taste which changes the dish a lot; not inherently bad, but it feels a lot less like traditional daal; seed oils are less healthy and we don’t recommend them; ghee is a traditional option and not bad in moderation, but not as healthy as the oils we mentioned first)
    • Water for cooking the lentils

    Method

    (we suggest you read everything at least once before doing anything)

    1) In a saucepan, boil water and add the lentils; let them simmer while doing the next things.

    2) Sauté the onions until translucent. This should only take a few minutes.

    3) Add the garlic, ginger, and hot peppers, and keep stirring for another couple of minutes.

    4) Add the ground spices (cumin, coriander, turmeric, garam masala) chili flakes, and cracked black pepper, as well as the salt or MSG if using (not both), and stir them in quickly but thoroughly.

    For the next step, you may need to transfer to larger pan if your sauté pan isn’t big enough to take the volume; if so, that’s fine, the sauté has done its job and can have a rest now. If your sauté pan is big enough, just carry on in the same pan; this is perfect.

    5) Add the lentils with the water you cooked them in (there might not be much water left now, as the lentils will have absorbed a lot of it; this is fine) as well as the chopped tomatoes.

    6) Simmer until it has the consistency of a very thick sauce (you can add a splash more water here and there if it seems to need more). In the West it’s common to serve lentils “al dente”, but in the East it’s usual to (for dishes like this) cook them until they start to

    7) Add the juice of at least 1/2 of your lime, or the whole lime if you feel so inclined.

    8) In a pre-heated skillet, flash-fry the sliced shallots and the seeds (cumin, coriander, mustard, black peppercorns) at the hottest temperature you can muster. Don’t worry if the oil smokes; we’re only going to be at this tadka-making stage for a moment and nothing will stick provided you keep it moving. When the seeds start popping, it’s ready. Add it all to the big pan and stir in.

    9) Add the cilantro-or-parsley garnish once you’re ready to serve.

    Enjoy!

    Learn more

    For those interested in some of the science of what we have going on today:

    Take care!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:

  • Which Tea Is Best, By Science?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    What kind of tea is best for the health?

    It’s popular knowledge that tea is a healthful drink, and green tea tends to get the popular credit for “healthiest”.

    Is that accurate? It depends on what you’re looking for…

    Black

    Its strong flavor packs in lots of polyphenols, often more than other kinds of tea. This brings some great benefits:

    As well as effects beyond the obvious:

    The Effect of Black Tea on Blood Pressure: A Systematic Review with Meta-Analysis of Randomized Controlled Trials

    …and its cardioprotective benefits aren’t just about lowering blood pressure; it improves triglyceride levels as well as improving the LDL to HDL ratio:

    The effect of black tea on risk factors of cardiovascular disease in a normal population

    Finally (we could say more, but we only have so much room), black tea usually has the highest caffeine content, compared to other teas.

    That’s good or bad depending on your own physiology and preferences, of course.

    White

    White tea hasn’t been processed as much as other kinds, so this one keeps more of its antioxidants, but that doesn’t mean it comes out on top; in this study of 30 teas, the white tea options ranked in the mid-to-low 20s:

    Phenolic Profiles and Antioxidant Activities of 30 Tea Infusions from Green, Black, Oolong, White, Yellow and Dark Teas

    White tea is also unusual in its relatively high fluoride content, which is consider a good thing:

    White tea: A contributor to oral health

    In case you were wondering about the safety of that…

    Water Fluoridation: Is It Safe, And How Much Is Too Much?

    Green

    Green tea ranks almost as high as black tea, on average, for polyphenols.

    Its antioxidant powers have given it a considerable anti-cancer potential, too:

    …and many others, but you get the idea. Notably:

    Green Tea Catechins: Nature’s Way of Preventing and Treating Cancer

    …or to expand on that:

    Potential Therapeutic Targets of Epigallocatechin Gallate (EGCG), the Most Abundant Catechin in Green Tea, and Its Role in the Therapy of Various Types of Cancer

    About green tea’s much higher levels of catechins, they also have a neuroprotective effect:

    Simultaneous Manipulation of Multiple Brain Targets by Green Tea Catechins: A Potential Neuroprotective Strategy for Alzheimer and Parkinson Diseases

    Green tea of course is also a great source of l-theanine, which we could write a whole main feature about, and we did:

    L-Theanine: What’s The Tea?

    Red

    Also called “rooibos” or (literally translated from Afrikaans to English) “redbush”, it’s quite special in that despite being a “true tea” botanically and containing many of the same phytochemicals as the other teas, it has no caffeine.

    There’s not nearly as much research for this as green tea, but here’s one that stood out:

    Effects of rooibos (Aspalathus linearis) on oxidative stress and biochemical parameters in adults at risk for cardiovascular disease

    However, in the search for the perfect cup of tea (in terms of phytochemical content), another set of researchers found:

    ❝The optimal cup was identified as sample steeped for 10 min or longer. The rooibos consumers did not consume it sufficiently, nor steeped it long enough. ❞

    ~ Dr. Hannelise Piek et al.

    Read in full: Rooibos herbal tea: an optimal cup and its consumers

    Bottom line

    Black, white, green, and red teas all have their benefits, and ultimately the best one for you will probably be the one you enjoy drinking, and thus drink more of.

    If trying to choose though, we offer the following summary:

    • 🖤 Black tea: best for total beneficial phytochemicals
    • 🤍 White tea:best for your oral health
    • 💚 Green tea: best for your brain
    • ❤️ Red tea: best if you want naturally caffeine-free

    Enjoy!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails: