Hair Growth: Caffeine and Minoxidil Strategies
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Questions and Answers at 10almonds
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This newsletter has been growing a lot lately, and so have the questions/requests, and we love that! In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!
As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!
So, no question/request too big or small
Hair growth strategies for men combing caffeine and minoxidil?
Well, the strategy for that is to use caffeine and minoxidil! Some more specific tips, though:
- Both of those things need to be massaged (gently!) into your scalp especially around your hairline.
- In the case of caffeine, that boosts hair growth. No extra thought or care needed for that one.
- In the case of minoxidil, it reboots the hair growth cycle, so if you’ve only recently started, don’t be surprised (or worried) if you see more shedding in the first three months. It’s jettisoning your old hairs because new ones were just prompted (by the minoxidil) to start growing behind them. So: it will get briefly worse before it gets better, but then it’ll stay better… provided you keep using it.
- If you’d like other options besides minoxidil, finasteride is a commonly prescribed oral drug that blocks the conversion of testosterone to DHT, which latter is what tells your hairline to recede.
- If you’d like other options besides prescription drugs, saw palmetto performs comparably to finasteride (and works the same way).
- You may also want to consider biotin supplementation if you don’t already enjoy that
- Consider also using a dermaroller on your scalp. If you’re unfamiliar, this is a device that looks like a tiny lawn aerator, with many tiny needles, and you roll it gently across your skin.
- It can be used for promoting hair growth, as well as for reducing wrinkles and (more slowly) healing scars.
- It works by breaking up the sebum that may be blocking new hair growth, and also makes the skin healthier by stimulating production of collagen and elastin (in response to the thousands of microscopic wounds that the needles make).
- Sounds drastic, but it doesn’t hurt and doesn’t leave any visible marks—the needles are that tiny. Still, practise good sterilization and ensure your skin is clean when using it.
See: How To Use A Dermaroller ← also explains more of the science of it
PS: this question was asked in the context of men, but the information goes the same for women suffering from androgenic alepoceia—which is a lot more common than most people think!
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Enjoy Bitter Foods For Your Heart & Brain
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When Bitter Is Better
A good general rule of thumb for “does this food contain a lot of healthy polyphenols?” is:
“is this (edible) plant bitter/astringent/pungent”?
If it is, it’s probably rich in polyphenols:
Deciphering the role of bitter and astringent polyphenols in promoting well-being
…which is why it’s no surprise that black coffee and bitter chocolate score highly, as do hot peppers and even garlic.
See also: Our Top 5 Spices: How Much Is Enough For Benefits?
Even fruits, generally considered something sweet to eat, often contain more polyphenols when they are bitter—many berries are great examples of this!
Read more: Goji Berries: Which Benefits Do They Really Have?
You can read more about the science of this here:
Sensory Nutrition and Bitterness and Astringency of Polyphenols
Important for multiple reasons (including heart and brain health)
Polyphenols have many benefits, and they’re most well known for their heart-healthy properties, but their antioxidant effect (and other mechanisms) also means these foods are generally neuroprotectants too:
The science of this is not all as obvious as you might think!
It is reasonable to expect “ok, this has antioxidant effect, so it will reduce oxidative damage to brain cells too”, and while that is true (and yes, polyphenols do cross the blood-brain barrier), they also help in other ways, including through the gut:
What if I don’t like bitter/astringent/pungent foods?
If you do not have a medical condition that proscribes them (do check with your doctor if unsure), the best advice is to simply eat them anyway, and your tastes will adapt.
It will also help if you avoid sweet foods (though this too is also a good general rule of thumb!), as this will move the balance of where your brain’s “set range” is for “good taste”.
Bonus tip: dark chocolate (80%+ cocoa if possible, 95% if you can get it) and chilli peppers go great with each other. Here’s an example of a chilli chocolate product on Amazon; it’s 70% cocoa (which is not bad, but could be better). You might be able to get a higher percentage locally, especially if you ask your local chocolatière, or make it yourself!
Enjoy!
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What Do The Different Kinds Of Fiber Do? 30 Foods That Rank Highest
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We’ve talked before about how important fiber is:
Why You’re Probably Not Getting Enough Fiber (And How To Fix It)
And even how it’s arguably the most important dietary factor when it comes to avoiding heart disease:
What Matters Most For Your Heart? Eat More (Of This) For Lower Blood Pressure ← Spoiler: it’s fiber
And yes, that’s even when considered alongside other (also laudable) dietary interventions such as lowering intake of sodium, various kinds of saturated fat, and red meat.
So, what should we know about fiber, aside from “aim to get nearer 40g/day instead of the US average 16g/day”?
Soluble vs Insoluble
The first main way that dietary fibers can be categorized is soluble vs insoluble. Part of the difference is obvious, but bear with us, because there’s more to know about each:
- Soluble fiber dissolves (what a surprise) in water and, which part is important, forms a gel. This slows down things going through your intestines, which is important for proper digestion and absorption of nutrients (as well as avoiding diarrhea). Yes, you heard right: getting enough of the right kind of fiber helps you avoid diarrhea.
- Insoluble fiber does not dissolve (how shocking) in water and thus mostly passes through undigested by us (some will actually be digested by gut microbes who subsist on this, and in return for us feeding them daily, they make useful chemicals for us). This kind of fiber is also critical for healthy bowel movements, because without it, constipation can ensue.
Both kinds of fiber improve just about every metric related to blood, including improving triglycerides and improving insulin sensitivity and blood glucose levels. Thus, they help guard against various kinds of cardiovascular disease, diabetes, and metabolic disease in general. Do note that because whatever’s good for your heart/blood is good for your brain (which requires a healthy heart and bloodstream to nourish it and take away waste), likely this also has a knock-on effect against cognitive decline, but we don’t have hard science for that claim so we’re going to leave that last item as a “likely”.
However, one thing’s for sure: if you want a healthy gut, heart, and brain, you need a good balance of soluble and insoluble fibers.
10 of the best for soluble fiber
Food Soluble Fiber Type(s) Soluble Fiber (g per serving) Insoluble Fiber Type(s) Insoluble Fiber (g per serving) Total Fiber (g per serving) Kidney beans (1 cup cooked) Pectin, Resistant Starch 1.5–2 Hemicellulose, Cellulose 6 8 Lentils (1 cup cooked) Pectin, Resistant Starch 1.5–2 Cellulose 6 7.5 Barley (1 cup cooked) Beta-glucan 3–4 Hemicellulose 2 6 Brussels sprouts (1 cup cooked) Pectin 1–1.5 Cellulose, Hemicellulose 2 3.5 Oats (1 cup cooked) Beta-glucan 2–3 Cellulose 1 3 Apples (1 medium) Pectin 1–2 Cellulose, Hemicellulose 2 3 Carrots (1 cup raw) Pectin 1–1.5 Cellulose, Hemicellulose 2 3 Citrus fruits (orange, 1 medium) Pectin 1–1.5 Cellulose 1 2.5 Flaxseeds (2 tbsp) Mucilage, Lignin 1–1.5 Cellulose 1 2.5 Psyllium husk (1 tbsp) Mucilage 3–4 Trace amounts 0 3–4 10 of the best for insoluble fiber
Food Soluble Fiber Type(s) Soluble Fiber (g per serving) Insoluble Fiber Type(s) Insoluble Fiber (g per serving) Total Fiber (g per serving) Wheat bran (1 cup) Trace amounts 0 Cellulose, Lignin 6–8 6–8 Black beans (1 cup cooked) Pectin, Resistant Starch 1.5 Cellulose 6 7.5 Brown rice (1 cup cooked) Trace amounts 0.5 Hemicellulose, Lignin 2–3 2.5–3.5 Popcorn (3 cups popped) Trace amounts 0.5 Hemicellulose 3 3.5 Broccoli (1 cup cooked) Pectin 1 Cellulose, Hemicellulose 4 5 Green beans (1 cup cooked) Trace amounts 0.5 Cellulose, Hemicellulose 3 3.5 Sweet potatoes (1 cup cooked) Pectin 1–1.5 Cellulose 3 4.5 Whole wheat bread (1 slice) Trace amounts 0.5 Cellulose, Hemicellulose 1 1.5 Pears (1 medium) Pectin 1 Cellulose, Hemicellulose 4 5 Almonds (1 oz) Trace amounts 0.5 Cellulose, Hemicellulose 2 2.5 10 of the best for a balance of both
Food Soluble Fiber Type(s) Soluble Fiber (g per serving) Insoluble Fiber Type(s) Insoluble Fiber (g per serving) Total Fiber (g per serving) Raspberries (1 cup) Pectin 1 Cellulose 5 6 Edamame (1 cup cooked) Pectin 1 Cellulose 5 6 Chia seeds (2 tbsp) Mucilage, Pectin 2–3 Lignin, Cellulose 3 5.5 Artichokes (1 medium) Inulin 1 Cellulose, Hemicellulose 5 6 Avocado (1 medium) Pectin ~2 Cellulose 4 6 Black beans (1 cup cooked) Pectin, Resistant Starch 1.5 Cellulose 6 7.5 Quinoa (1 cup cooked) Pectin, Saponins 1 Cellulose, Hemicellulose 3 4 Spinach (1 cup cooked) Pectin 0.5 Cellulose, Lignin 3 3.5 Prunes (1/2 cup) Pectin, Sorbitol 2 Cellulose 4 6 Figs (3 medium) Pectin 1 Cellulose 2 3 You’ll notice that the above “balance” is not equal; that’s ok; we need greater quantities of insoluble than soluble anyway, so it is as well that nature provides such.
This is the same kind of balance when we talk about “balanced hormones” (does not mean all hormones are in equal amounts; means they are in the right proportions) or “balanced microbiome” (does not mean that pathogens and friendly bacteria are in equal numbers), etc.
Some notes on the above:
About those fiber types, some of the most important soluble ones to aim for are:
- Beta-glucan: found in oats and barley, it supports heart health.
- Pectin: found in fruits like apples, citrus, and pears, it helps with cholesterol control.
- Inulin: a type of prebiotic fiber found in artichokes.
- Lignin: found in seeds and wheat bran, it has antioxidant properties.
- Resistant starch: found in beans and lentils, it acts as a prebiotic for gut health.
See also: When Is A Fiber Not A Fiber? The Food Additive You Do Want
One fiber to rule them all
Well, not entirely (we still need the others) but there is a best all-rounder:
The Best Kind Of Fiber For Overall Health?
Enjoy!
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Hold Me Tight – by Dr. Sue Johnson
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A lot of relationship books are quite wishy-washy. This one isn’t.
This one is evidenced-based (and heavily referenced!), and yet at the same time as being deeply rooted in science, it doesn’t lose the human touch.
Dr. Johnson has spent her career as a clinical psychologist and researcher; she’s the primary developer of Emotionally Focused Therapy (EFT), which has demonstrated its effectiveness in over 35 years of peer-reviewed clinical research. In other words, it works.
EFT—and thus also this book—finds roots in Attachment Theory. As such, topics this book covers include:
- Recognizing and recovering from attachment injury
- How fights in a relationship come up, and how they can be avoided
- How lot of times relationships end, it’s not because of fights, but a loss of emotional connection
- Building a lifetime of love instead, falling in love again each day
This book lays the groundwork for ensuring a strong, secure, ongoing emotional bond, of the kind that makes/keeps a relationship joyful and fulfilling.
Dr. Johnson has been recognized in her field with a Lifetime Achievement Award, and the Order of Canada.
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Taking a drug like Ozempic? What you need to know about risks of suicidal thoughts and contraception failure
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The rise of GLP-1 drugs such as Ozempic and Mounjaro has been nothing short of meteoric. Originally developed to treat diabetes, these drugs are now widely used for weight loss and have become household names.
But alongside headlines of dramatic transformations are reports of an increased risk of suicidal thoughts and unwanted pregnancies after contraception failures.
So what are the risks? And what should you do if you are taking these medicines?
How do these drugs work?
Glucagon-like peptide-1 (GLP-1) drugs are medicines used to treat type-2 diabetes and obesity. They work by reducing blood sugar levels and reducing appetite.
Five medicines in this category are approved for use in Australia:
- Mounjaro (tirzepatide)
- Ozempic (semaglutide)
- Wegovy (semaglutide)
- Saxenda (liraglutide)
- Trulicity (dulaglutide).
These drugs have been around for the past decade but rose in popularity in recent years, with the help of Hollywood celebrities.
The most common side effects of GLP-1 medicines are related to digestion: nausea, vomiting, diarrhoea, indigestion, stomach pain and constipation. These tend to be mild and either go away with time or become more tolerable.
But more concerning side effects have prompted Australia’s Therapeutic Goods Administration (TGA) to issue new warnings this week about suicidal thoughts and the lower effectiveness of oral contraceptives.
Risk of suicidal thoughts and behaviour
In the 12 months to November 2025, there were 20 cases of suicidal thoughts reported in the Australian Database of Adverse Events Notifications which coincided with the use of a GLP-1 medicine.
This is consistent with published scientific data. A 2024 study found a link between GLP-1 medicines and a 106% increase in the risk of suicidal behaviour.
An analysis of World Health Organization data also found a link between semaglutide use and suicidal thoughts.
But not all the evidence supports a link between GLP-1 drugs and suicidal thoughts.
A separate 2024 sudy analysed the data of more than 1.8 million patients who were taking the medicines for either weight loss or diabetes. It found a lower, not higher, risk of new or recurring suicidal thoughts when compared with patients who were not taking a GLP-1 medicine.
How can these drugs affect contraception?
Oral contraceptives work by using hormones to prevent the releases of eggs from the ovaries and to thicken the cervical mucus. This latter effect makes it difficult for sperm to reach and fertilise an egg.
These effects are only triggered when pregnancy-related hormones are at a high enough level. If GLP-1 medicines affect how the body absorbs hormones in oral contraceptives, hormone levels may not reach concentrations high enough to prevent pregnancy.
Researchers first raised the potential for GLP-1 medicines to affect oral contraceptives in 2003.
The ability for GLP-1 medicines to affect oral contraceptives may vary between drugs. A review that examined the link between tirzepatide and oral contraception found that this specific drug had a higher impact on hormone absorption when compared with other GLP-1 drugs.
A study of semagutide published in 2015 found the drug did not affect the amount of hormone that was absorbed into the body when patients were given the commonly used oral contraceptive pills ethinylestradiol or levonorgestrel.
But a more recent study in 2025 concluded that both tirzepatide and oral semaglutide were able to affect oral contraceptive hormone levels.
GLP-1 drugs should not affect the efficacy of IUDs or other long-acting (implanted) contraceptives as they are not reliant on hormones being absorbed from the stomach.
I’m taking one of these drugs, what should I do?
The TGA recommends that if you’re taking GLP-1 medicines, you should tell your doctor if you experience new or worsening depression, suicidal thoughts, or any unusual changes in mood or behaviour.
For women taking the GLP-1 drug tirzepatide and oral contraceptives, the TGA advises either switching to a non-oral contraceptive (like an implant), or adding a barrier method of contraception for four weeks after first taking the GLP-1 medicine, or any time you increase the dose of tirzepatide.
A GLP-1 drug should not be used during pregnancy, as it may affect fetal growth. The adverse events database has also reported cases of miscarriages in women who were at the time taking semaglutide or tirzepatide.
If this article has raised issues for you, or if you’re concerned about someone you know, call Lifeline on 13 11 14 or the Suicide Call Back Service on 1300 659 467
Nial Wheate, Professor, School of Natural Sciences, Macquarie University
This article is republished from The Conversation under a Creative Commons license. Read the original article.
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The Problem With Sweeteners
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The WHO’s view on sugar-free sweeteners
The WHO has released a report offering guidance regards the use of sugar-free sweeteners as part of a weight-loss effort.
In a nutshell, the guidance is: don’t
- Here’s the report itself: Use of non-sugar sweeteners: WHO guideline
- Here’s the WHO’s own press release about it: WHO advises not to use non-sugar sweeteners for weight control in newly released guideline
- And it was based on this huge systematic review: Health effects of the use of non-sugar sweeteners: a systematic review and meta-analysis
They make for interesting reading, so if you don’t have time now, you might want to just quickly open and bookmark them for later!
Some salient bits and pieces:
Besides that some sweeteners can cause gastro-intestinal problems, a big problem is desensitization:
Because many sugar substitutes are many times (in some cases, hundreds of times) sweeter than sugar, this leads to other sweet foods tasting more bland, causing people to crave sweeter and sweeter foods for the same satisfaction level.
You can imagine how that’s not a spiral that’s good for the health!
The WHO recommendation applies to artificial and naturally-occurring non-sugar sweeteners, including:
- Acesulfame K
- Advantame
- Aspartame
- Cyclamates
- Neotame
- Saccharin
- Stevia
Sucralose and erythritol, by the way, technically are sugars, just not “that kind of sugar” so they didn’t make the list of non-sugar sweeteners.
That said, a recent study did find that erythritol was linked to a higher risk of heart attack, stroke, and early death, so it may not be an amazing sweetener either:
Read: The artificial sweetener erythritol and cardiovascular event risk
Want to know a good way of staying healthy in the context of sweeteners?
Just get used to using less. Your taste buds will adapt, and you’ll get just as much pleasure as before, from progressively less sweetening agent.
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Younger Next Year: The Exercise Program – by Chris Crowley & Dr. Henry Lodge
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We previously reviewed the same authors’ original “Younger Next Year”, and now here’s the more specific book about exercise for increasing healthspan and reversing markers of biological aging, going into much more detail in that regard.
How much more? Well, it’s a very hand-holding book in the sense that it walks the reader through everything step-by-step, tells not only what kind of exercise and how much, but also how to do, what things to do to prepare, how to avoid not erring in various ways, what metrics to keep an eye on to ensure you are making progress, and more.
There are also whole sections on specific common age-related issues including osteoporosis and arthritis, as well as how to train around injuries (especially of the kind that basically aren’t likely to ever fully go away).
As with the previous book, there’s a blend of motivational pep talk and science—this book is heavily weighted towards the former. It has, however, enough science to keep it on the right track throughout. Hence the two authors! Crowley for motivational pep and training tips, and Dr. Lodge for the science.
Bottom line: if you’d like to be biologically younger next year, that exercise will be an important component of that, and this book is really quite comprehensive for its relative brevity (weighing in at 176 pages).
Click here to check out Younger Next Year: The Exercise Program, and make that progress!
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