Are GMOs Good Or Bad For Us?

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Unzipping Our Food’s Genes

In yesterday’s newsletter, we asked you for your (health-related) views on GMOs.

But what does the science say?

First, a note on terms

Technically, we (humans) have been (g)enetically (m)odifying (o)rganisms for thousands of years.

If you eat a banana, you are enjoying the product of many generations of artificial selection, to change its genes to produce a fruit that is soft, sweet, high in nutrients, and digestible without cooking. The original banana plant would be barely recognizable to many people now (and also, barely edible). We’ve done similarly with countless other food products.

So in this article, we’re going to be talking exclusively about modern genetic modification of organisms, using exciting new (ish, new as in “in the last century”) techniques to modify the genes directly, in a copy-paste fashion.

For more details on the different kinds of genetic modification of organisms, and how they’re each done (including the modern kinds), check out this great article from Sciencing, who explain it in more words than we have room for here:

Sciencing | How Are GMOs Made?

(the above also offers tl;dr section summaries, which are great too)

GMOS are outright dangerous (cancer risks, unknown risks, etc): True or False?

False, so far as we know, in any direct* fashion. Obviously “unknown risks” is quite a factor, since those are, well, unknown. But GMOs on the market undergo a lot of safety testing, and have invariably passed happily.

*However! Glyphosate (the herbicide), on the other hand, has a terrible safety profile and is internationally banned in very many countries for this reason.

Why is this important? Because…

  • in the US (and two out of ten Canadian provinces), glyphosate is not banned
  • In the US (and we may hypothesize, those two Canadian provinces) one of the major uses of genetic modification of foodstuffs is to make it resistant to glyphosate
  • Consequently, GMO foodstuffs grown in those places have generally been liberally doused in glyphosate

So… It’s not that the genetic modification itself makes the food dangerous and potentially carcinogenic (it doesn’t), but it is that the genetic modification makes it possible to use a lot more glyphosate without losing crops to glyphosate’s highly destructive properties.

Which results in the end-consumer eating glyphosate. Which is not good. For example:

❝Following the landmark case against Monsanto, which saw them being found liable for a former groundskeeper, 46 year old Dewayne Johnson’s cancer, 32 countries have to date banned the use of Glyphosate, the key ingredient in Monsanto’s Roundup weed killer. The court awarded Johnson R4.2 billion in damages finding Monsanto “acted with malice or oppression”.❞

Source: see below!

You can read more about where glyphosate is and isn’t banned, here:

33 countries ban the use of Glyphosate—the key ingredient in Roundup

For the science of this (and especially the GMO → glyphosate use → cancer pipeline), see:

Use of Genetically Modified Organism (GMO)-Containing Food Products in Children

GMOs are extra healthy because of the modifications (they were designed for that, right?): True or False?

True or False depending on who made them and why! As we’ve seen above, not all companies seem to have the best interests of consumer health in mind.

However, they can be! Here are a couple of great examples:

❝Recently, two genome-edited crops targeted for nutritional improvement, high GABA tomatoes and high oleic acid soybeans, have been released to the market.

Nutritional improvement in cultivated crops has been a major target of conventional genetic modification technologies as well as classical breeding methods❞

Source: Drs. Nagamine & Ezura

Read in full: Genome Editing for Improving Crop Nutrition

(note, they draw a distinction of meaning between genome editing and genetic modification, according to which of two techniques is used, but for the purposes of our article today, this is under the same umbrella)

Want to know more?

If you’d like to read more about this than we have room for here, here’s a great review in the Journal of Food Science & Nutrition:

Should we still worry about the safety of GMO foods? Why and why not? A review

Take care!

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  • Kale vs Watercress – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing kale to watercress, we picked the kale.

    Why?

    It was very close! If ever we’ve been tempted to call something a tie, this has been the closest so far.

    Their macros are close; watercress has a tiny amount more protein and slightly lower carbs, but these numbers are tiny, so it’s not really a factor. Nevertheless, on macros alone we’d call this a slight nominal win for watercress.

    In terms of vitamins, they’re even. Watercress has higher vitamin E and choline (sometimes considered a vitamin), as well as being higher in some B vitamins. Kale has higher vitamins A and K, as well as being higher in some other B vitamins.

    In the category of minerals, watercress has higher calcium, magnesium, phosphorus, and potassium, while kale has higher copper, iron, manganese, and zinc. The margins are slightly wider for kale’s more plentiful minerals though, so we’ll call this section a marginal win for kale.

    When it comes to polyphenols, kale takes and maintains the lead here, with around 2x the quercetin and 27x the kaempferol. Watercress does have some lignans that kale doesn’t, but ultimately, kale’s strong flavonoid content keeps it in the lead.

    So of course: enjoy both if both are available! But if we must pick one, it’s kale.

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  • Outsmart Your Pain – by Dr. Christiane Wolf

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Dr. Wolf is a physician turned mindfulness teacher. As such, and holding an MD as well as a PhD in psychosomatic medicine, she knows her stuff.

    A lot of what she teaches is mindfulness-based stress reduction (MBSR), but this book is much more specific than that. It doesn’t promise you won’t continue to experience pain—in all likelihood you will—but it does change the relationship with pain, and this greatly lessens the suffering and misery that comes with it.

    For many, the most distressing thing about pain is not the sensation itself, but how crippling it can be—getting in the way of life, preventing enjoyment of other things, and making every day a constant ongoing exhausting battle… And every night, a “how much rest am I actually going to be able to get, and in what condition will I wake up, and how will I get through tomorrow?” stress-fest.

    Dr. Wolf helps the reader to navigate through all these challenges and more; minimize the stress, maximize the moments of respite, and keep pain’s interference with life to a minimum. Each chapter addresses different psychological aspects of chronic pain management, and each comes with specific mindfulness meditations to explore the new ideas learned.

    The style is personal and profound, while coming from a place of deep professional understanding as well as compassion.

    Bottom line: if you’ve been looking for a life-ring to help you reclaim your life, this one could be it; we wholeheartedly recommend it.

    Click here to check out Outsmart Your Pain, and recover the beauty and joy of life!

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  • What Is Earwax & Should You Get Rid Of It?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Earwax (cerumen) forms in the outer ear canal when dead skin cells mix with oily sweat (a specialty of the apocrine glands) and sebum, a fatty substance mostly associated with facial oiliness. But, does it have a purpose, or is it just a waste product?

    Nature is (mostly) best in this case

    Earwax plays an important role in ear health, acting as a natural lubricant that prevents dryness and itchiness, trapping debris and microbes, and forming a protective barrier for the ear canal. It even contains proteins that help fight bacterial infections.

    As for removal: the body has a natural mechanism for removing excess earwax: as skin cells grow, they migrate outward, carrying earwax with them.

    In contrast, manual removal of earwax can do more harm than good. Using swabs or other items often pushes wax deeper, risks damaging the ear canal, and disrupts its protective barrier, potentially leading to infection.

    Ear candling, which claims to extract earwax, not only does not work (its main premise has been actively disproven and clinical evidence shows unequivocally that it doesn’t work by any mysterious method either; it just plain doesn’t work), but also can cause injuries and will tend to leave more harmful debris behind than was there originally.

    For those prone to earwax buildup, over-the-counter eardrops can help soften wax for natural removal, and medical professionals have safe methods to clear blockages if necessary.

    To maintain ear health, it’s best to clean only the outer ear with a damp cloth, limit the use of earplugs or earbuds, and generally leave earwax alone unless it causes discomfort or hearing issues.

    For more on all of this, enjoy:

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    Want to learn more?

    You might also like to read:

    Ear Candling: Is It Safe & Does It Work? ← the answer is “no and no”, but the science may interest you

    Take care!

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  • Hanging Exercises For Complete Beginners & Older Adults

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    Hanging (not the kind with a gallows) is great for the heath, improving not just strength and mobility, but also—critically—looking after spinal health too. Amanda Raynor explains in this video how this exercise is accessible to anyone (unless you have no arms, in which case, sorry, this one is just not for you—though hanging by your legs will also give similar spinal benefits!).

    Hanging out

    Hanging can be done at home or at a park, with minimal equipment (a bar, a sturdy tree branch, etc).

    Note: the greater the diameter of the bar, the more it will work your grip strength, and/but the harder it will be. So, it’s recommend to start with a narrow-diameter bar first.

    Getting started:

    • Start with a “dead hang”: grip the bar with hands shoulder-width apart, thumb wrapped around.
    • Aim to hang without pulling up; build endurance gradually (10–30 seconds is fine at first).
    • Work up to holding for 60 seconds in three sets as a fitness goal.

    Progression:

    • If unable to hang at all initially, use a chair or stool to support some body weight.
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    • Start with 10 seconds, progressing by small increments (e.g: 15, 20, 25 seconds) until reaching 60 seconds.

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    • Move the body while hanging (e.g., circles, knee lifts).
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  • A Correction, And A New, Natural Way To Boost Daily Energy Levels

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s Q&A Day at 10almonds!

    Have a question or a request? You can always hit “reply” to any of our emails, or use the feedback widget at the bottom!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    First: a correction and expansion!

    After yesterday’s issue of 10almonds covering breast cancer risks and checks, a subscriber wrote to say, with regard to our opening statement, which was:

    Anyone (who has not had a double mastectomy, anyway) can get breast cancer”

    ❝I have been enjoying your newsletter. This statement is misleading and should have a disclaimer that says even someone who has had a double mastectomy can get breast cancer, again. It is true and nothing…nothing is 100% including a mastectomy. I am a 12 year “thriver” (I don’t like to use the term survivor) who has had a double mastectomy. I work with a local hospital to help newly diagnosed patients deal with their cancer diagnosis and the many decisions that follow. A double mastectomy can help keep recurrence from happening but there are no guarantees. I tried to just delete this and let it go but it doesn’t feel right. Thank you!❞

    Thank you for writing in about this! We wouldn’t want to mislead, and we’re always glad to hear from people who have been living with conditions for a long time, as (assuming they are a person inclined to learning) they will generally know topics far more deeply than someone who has researched it for a short period of time.

    Regards a double mastectomy (we’re sure you know this already, but noting here for greater awareness, prompted by your message), a lot of circumstances can vary. For example, how far did a given cancer spread, and especially, did it spread to the lymph nodes at the armpits? And what tissue was (and wasn’t) removed?

    Sometimes a bilateral prophylactic mastectomy will leave the lymph nodes partially or entirely intact, and a cancer could indeed come back, if not every last cancerous cell was removed.

    A total double mastectomy, by definition, should have removed all tissue that could qualify as breast tissue for a breast cancer, including those lymph nodes. However, if the cancer spread unnoticed somewhere else in the body, then again, you’re quite correct, it could come back.

    Some people have a double mastectomy without having got cancer first. Either because of a fear of cancer due to a genetic risk (like Angelina Jolie), or for other reasons (like Elliot Page).

    This makes a difference, because doing it for reasons of cancer risk may mean surgeons remove the lymph nodes too, while if that wasn’t a factor, surgeons will tend to leave them in place.

    In principle, if there is no breast tissue, including lymph nodes, and there was no cancer to spread, then it can be argued that the risk of breast cancer should now be the same “zero” as the risk of getting prostate cancer when one does not have a prostate.

    But… Surgeries are not perfect, and everyone’s anatomy and physiology can differ enough from “textbook standard” that surprises can happen, and there’s almost always a non-zero chance of certain health outcomes.

    For any unfamiliar, here’s a good starting point for learning about the many types of mastectomy, that we didn’t go into in yesterday’s edition. It’s from the UK’s National Health Service:

    NHS: Mastectomy | Types of Mastectomy

    And for the more sciency-inclined, here’s a paper about the recurrence rate of cancer after a prophylactic double mastectomy, after a young cancer was found in one breast.

    The short version is that the measured incidence rate of breast cancer after prophylactic bilateral mastectomy was zero, but the discussion (including notes about the limitations of the study) is well worth reading:

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    ❝[Can you write about] the availability of geriatric doctors Sometimes I feel my primary isn’t really up on my 70 year old health issues. I would love to find a doctor that understands my issues and is able to explain them to me. Ie; my worsening arthritis in regards to food I eat; in regards to meds vs homeopathic solutions.! Thanks!❞

    That’s a great topic, worthy of a main feature! Because in many cases, it’s not just about specialization of skills, but also about empathy, and the gap between studying a condition and living with a condition.

    About arthritis, we’re going to do a main feature specifically on that quite soon, but meanwhile, you might like our previous article:

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    As for homeopathy, your question prompts our poll today!

    (and then we’ll write about that tomorrow)

    Don’t Forget…

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  • Glycemic Index vs Glycemic Load vs Insulin Index

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    How To Actually Use Those Indices

    Carbohydrates are essential for our life, and/but often bring about our early demise. It would be a very conveniently simple world if it were simply a matter of “enjoy in moderation”, but the truth is, it’s not that simple.

    To take an extreme example, for the sake of clearest illustration: The person who eats an 80% whole fruit diet (and makes up the necessary protein and fats etc in the other 20%) will probably be healthier than the person who eats a “standard American diet”, despite not practising moderation in their fruit-eating activities. The “standard American diet” has many faults, and one of those faults is how it promotes sporadic insulin spikes leading to metabolic disease.

    If your breakfast is a glass of orange juice, this is a supremely “moderate” consumption, but an insulin spike is an insulin spike.

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    Glycemic Index

    The first tool in our toolbox here is glycemic index, or GI.

    GI measures how much a carb-containing food raises blood glucose levels, also called blood sugar levels, but it’s just glucose that’s actually measured, bearing in mind that more complex carbs will generally get broken down to glucose.

    Pure glucose has a GI of 100, and other foods are ranked from 0 to 100 based on how they compare.

    Sometimes, what we do to foods changes its GI.

    • Some is because it changed form, like the above example of whole fruit (low GI) vs fruit juice (high GI).
    • Some is because of more “industrial” refinement processes, such as whole grain wheat (medium GI) vs white flour and white flour products (high GI)
    • Some is because of other changes, like starches that were allowed to cool before being reheated (or eaten cold).

    Broadly speaking, a daily average GI of 45 is considered great.

    But that’s not the whole story…

    Glycemic Load

    Glycemic Load, or GL, takes the GI and says “ok, but how much of it was there?”, because this is often relevant information.

    Refined sugar may have a high GI, but half a teaspoon of sugar in your coffee isn’t going to move your blood sugar levels as much as a glass of Coke, say—the latter simply has more sugar in, and just the same zero fiber.

    GL is calculated by (grams of carbs / 100) x GI, by the way.

    But it still misses some important things, so now let’s look at…

    Insulin Index

    Insulin Index, which does not get an abbreviation (probably because of the potentially confusing appearance of “II”), measures the rise in insulin levels, regardless of glucose levels.

    This is important, because a lot of insulin response is independent of blood glucose:

    • Some is because of other sugars, some some is in response to fats, and yes, even proteins.
    • Some is a function of metabolic base rate.
    • Some is a stress response.
    • Some remains a mystery!

    Another reason it’s important is that insulin drives weight gain and metabolic disorders far more than glucose.

    Note: the indices of foods are calculated based on average non-diabetic response. If for example you have Type 1 Diabetes, then when you take a certain food, your rise in insulin is going to be whatever insulin you then take, because your body’s insulin response is disrupted by being too busy fighting a civil war in your pancreas.

    If your diabetes is type 2, or you are prediabetic, then a lot of different things could happen depending on the stage and state of your diabetes, but the insulin index is still a very good thing to be aware of, because you want to resensitize your body to insulin, which means (barring any urgent actions for immediate management of hyper- or hypoglycemia, obviously) you want to eat foods with a low insulin index where possible.

    Great! What foods have a low insulin index?

    Many factors affect insulin index, but to speak in general terms:

    • Whole plant foods are usually top-tier options
    • Lean and/or white meats generally have lower insulin index than red and/or fatty ones
    • Unprocessed is generally lower than processed
    • The more solid a food is, generally the lower its insulin index compared to a less solid version of the same food (e.g. baked potatoes vs mashed potatoes; cheese vs milk, etc)

    But do remember the non-food factors too! This means where possible:

    • reducing/managing stress
    • getting frequent exercise
    • getting good sleep
    • practising intermittent fasting

    See for example (we promise you it’s relevant):

    Fix Chronic Fatigue & Regain Your Energy, By Science

    …as are (especially recommendable!) the two links we drop at the bottom of that page; do check them out if you can

    Take care!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

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