Common Hospital Blood Pressure Mistake (Don’t Let This Happen To You Or A Loved One)

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There’s a major issue in healthcare, Dr. Suneel Dhand tells us, pertaining to the overtreatment of hypertension in hospitals. Here’s how to watch out for it and know when to question it:

Under pressure

When patients, particularly from older generations, are admitted to the hospital, their blood pressure often fluctuates due to illness, dehydration, and other factors. Despite this, they are often continued on their usual blood pressure medications, which can lead to dangerously low blood pressure.

Why does this happen? The problem arises from rigid protocols that dictate stopping blood pressure medication only if systolic pressure is below a certain threshold, often 100. However, Dr. Dhand argues that 100 is already low*, and administering medication when blood pressure is close to this can cause it to drop dangerously lower

*10almonds note: low for an adult, anyway, and especially for an older adult. To be clear: it’s not a bad thing! That is the average systolic blood pressure of a healthy teenager and it’s usually the opposite of a problem if we have that when older (indeed, this very healthy writer’s blood pressure averages 100/70, and suffice it to say, it’s been a long time since I was a teenager). But it does mean that we definitely don’t want to take medications to artificially lower it from there.

Low blood pressure from overtreatment can lead to severe consequences, requiring emergency interventions to stabilize the patient.

Dr. Dhand’s advice for patients and families is:

  • Ensure medication accuracy: make sure the medical team knows the correct blood pressure medications and dosages for you or your loved one.
  • Monitor vital signs: actively check blood pressure readings, especially if they are in the low 100s or even 110s, and discuss any medication concerns with the medical team.
  • Watch for symptoms of low blood pressure: be alert for symptoms like dizziness or weakness, which could indicate dangerously low blood pressure.

For more on all of this, enjoy:

Click Here If The Embedded Video Doesn’t Load Automatically!

Want to learn more?

You might also like to read:

The Insider’s Guide To Making Hospital As Comfortable As Possible

Take care!

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  • The Emperor’s New Klotho, Or Something More?

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    Unzipping The Genes Of Aging?

    Klotho is an enzyme encoded in humans’ genes—specifically, in the KL gene.

    It’s found throughout all living parts of the human body (and can even circulate about in its hormonal form, or come to rest in its membranaceous form), and its subgroups are especially found:

    • α-klotho: in the brain
    • β-klotho: in the liver
    • γ-klotho: in the kidneys

    Great! Why do we care?

    Klotho, its varieties and variants, its presence or absence, are very important in aging.

    Almost every biological manifestation of aging in humans has some klotho-related indicator; usually the decrease or mutation of some kind of klotho.

    Which way around the cause and effect go has been the subject of much debate and research: do we get old because we don’t have enough klotho, or do we make less klotho because we’re getting old?

    Of course, everything has to be tested per variant and per system, so that can take a while (punctuated by research scientists begging for more grants to do the next one). Given that it’s about aging, testing in humans would take an incredibly long while, so most studies so far have been rodent studies.

    The general gist of the results of rodent studies is “reduced klotho hastens aging; increased klotho slows it”.

    (this can be known by artificially increasing or decreasing the level of klotho expression, again something easier in mice as it is harder to arrange transgenic humans for the studies)

    Here’s one example of many, of that vast set of rodent studies:

    Suppression of Aging in Mice by the Hormone Klotho

    Relevance for Alzheimer’s, and a science-based advice

    A few years ago (2020), an Alzheimer’s study was undertaken; they noted that the famous apolipoprotein E4 (apoE4) allele is the strongest genetic risk factor for Alzheimer’s, and that klotho may be another. FGF21 (secreted by the liver, mostly during fasting) binds to its own receptor (FGFR1) and its co-receptor β-klotho. Since this is a known neuroprotective factor, they wondered whether klotho itself may interact with β-amyloid (Aβ), and found:

    ❝Aβ can enhance the ability of klotho to draw FGF21 to regions of incipient neurodegeneration in AD❞

    ~ Dr. Lehrer & Dr. Rheinstein

    In other words: β-amyloid, the substance whose accumulation is associated with neurodegeneration in Alzheimer’s disease, is a mediator in klotho bringing a known neuroprotective factor, FGF21, to the areas of neurodegeneration

    In fewer words: klotho calls the firefighters to the scene of the fire

    Read more: Alignment of Alzheimer’s disease amyloid β-peptide and klotho

    The advice based on this? Consider practicing intermittent fasting, if that is viable for you, as it will give your liver more FGF21-secreting time, and the more FGF21, the more firefighters arrive when klotho sounds the alarm.

    See also: Intermittent Fasting: What’s the truth?

    …and while you’re at it:

    Does intermittent fasting have benefits for our brain?

    A more recent (2023) study with a slightly different (but connected) purpose, found results consistent with this:

    Longevity factor klotho enhances cognition in aged nonhuman primates

    …and, for that matter this (2023) study that found:

    Associations between klotho and telomere biology in high stress caregivers

    …which looks promising, but we’d like to see it repeated with a sounder method (they sorted caregiving into “high-stress” and “low-stress” depending on whether a child was diagnosed with ASD or not, which is by no means a reliable way of sorting this). They did ask for reported subjective stress levels, but to be more objective, we’d like to see clinical markers of stress (e.g. cortisol levels, blood pressure, heart rate changes, etc).

    A very recent (April 2024) study found that it has implications for more aspects of aging—and this time, in humans (but using a population-based cohort study, rather than lab conditions):

    The prognostic value of serum α-klotho in age-related diseases among the US population: A prospective population-based cohort study

    Can I get it as a supplement?

    Not with today’s technology and today’s paucity of clinical trials, you can’t. Maybe in the future!

    However… The presence of senescent (old, badly copied, stumbling and staggering onwards when they should have been killed and eaten and recycled already) cells actively reduces klotho levels, which means that taking supplements that are senolytic (i.e., that kill those senescent cells) can increase serum klotho levels:

    Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans

    Ok, what can I take for that?

    We wrote about a senolytic supplement that you might enjoy, recently:

    Fisetin: The Anti-Aging Assassin

    Want to know more?

    If you have the time, Dr. Peter Attia interviews Dr. Dena Dubal (researcher in several of the above studies) here:

    Click Here If The Embedded Video Doesn’t Load Automatically

    Enjoy!

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  • 3 Life-Changing Mobility Movements To Train

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    If you’ve ever momentarily struggled to stand up straight after sitting for too long, or had to take a moment to get up off the floor, this one’s for you.

    And if you’ve never done those things? Well, this one’s still for you—prevention is better than cure, after all!

    From the hips

    Most movements that we need to do in life depend on our hips. They support our spine, on which almost everything else depends, and on the flipside, they’re where our legs are plugged in, so they’re pretty critical for lower body mobility too.

    So, with that in mind, here are the three exercise promised—or five, depending on how you want to count them:

    1. For hip mobility most directly: start with a combination of donkey kicks and fire hydrants. From a tabletop position, lift one leg behind you as if putting a footprint on the ceiling, keeping your tailbone tucked in and your core engaged to avoid using your lower back. Then, bring your leg back and lift it sideways like a dog peeing on a hydrant, keeping your torso level and pelvis stable. Alternate between the two movements for 20 total reps (i.e. 10 each), then switch legs.
    2. For hip, spinal, and upper body mobility: now we get to thread the needle. From all fours, inhale and reach one arm up (as far as comfortable), then exhale and thread it under your body to the opposite side. Lower your shoulder close to the mat but without touching it, using your core to twist. Follow your breath rhythm—inhale to lift, exhale to thread—and do 10 reps on each side.
    3. For hip and ankle mobility: use a split lunge with two parts. From an upright lunge, put your hands on your front thigh and tuck your tailbone in to engage the back glute. Lunge forwards while keeping your front heel flat on the floor, while your knee moves past the toes. Then, without changing pelvis position, lift your back knee and try to straighten your leg, pushing your heel backwards without raising your hips. Return to start and repeat 10 times per side.

    For more on all of this plus visual demonstrations, enjoy:

    Click Here If The Embedded Video Doesn’t Load Automatically!

    Want to learn more?

    You might also like:

    How Tight Are Your Hips? Test (And Fix!) With This

    Take care!

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  • Do therapies like EMDR affect memories of traumatic events?

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    To recover from abuse or another traumatic experience, some people turn to a therapy called eye-movement desensitisation and reprocessing, or EMDR.

    But this may present problems if these people pursue justice in the courts. In New South Wales, for instance, evidence obtained using EMDR can’t be used in a case unless it has been approved by the director (or deputy) of public prosecutions.

    Prosecutors are concerned that after EMDR, trauma memories can’t be relied on as valid testimony. This has resulted in court cases not proceeding.

    But what does the evidence say?

    microgen/Getty Images

    What is EMDR?

    EMDR is one of the common exposure-based treatments for post-traumatic stress disorder (PTSD).

    This group of therapies – which encompass prolonged exposure, cognitive processing therapy, EMDR and other variants – all ask a patient to recall their trauma. The therapists integrates this information and aims to correct unhelpful thought patterns that may be prolonging their distress.

    Each of these treatments is recommended in most international guidelines for treating PTSD.

    EMDR is different from the other exposure-based therapies because the therapist also asks the patient to move their eyes in a rapid side-to-side movement. This will typically involve following the therapist’s fingers move back and forth.

    Proponents of EMDR initially proposed eye movements triggered neural processes that help people better adjust to or process trauma memories. However, the actual role of eye movements has been subject to much debate.

    Although the mechanism isn’t yet fully understood, the weight of evidence suggests eye movements may reduce distress while recounting trauma memories because it depletes our working memory capacity. This results in less focus on the negative emotions associated with the memory.

    Where did concerns about EMDR affecting memories come from?

    EMDR has been criticised for potentially distorting people’s memories of traumatic events dates since the 1990s when the treatment increased in popularity.

    This was also a period when when a controversial movement of “recovered memory therapies” emerged. These were used to guide people to reconstruct memories that were purportedly “hidden” or “repressed”.

    This involved therapists directing patients to focus attention on internal states, suspend reality and allow themselves to be guided by the therapist to recover so-called “repressed memories”, often of satanic or ritual abuse.

    In the wake of this movement, many studies showed this sort of guided intervention could lead to false, or even implanted, memories.

    At the same time, researchers were concerned about hypnotic techniques. During hypnosis, people could reconstruct false memories. They were particularly susceptible to misleading information and had stronger confidence in these memories.

    For this reason, authorities around the world cautioned against using hypnosis in cases that may involve the person subsequently needing to give testimony in legal proceedings.

    Some likened EMDR to hypnosis, others were sceptical of its claims

    Some agencies and experts considered EMDR a hypnosis-like intervention because it focused the person’s attention on their internal state, promoted increased absorption in memories and actively guided memories.

    Many also likened the finger waving in front of the patient’s face as inducing a hypnotic state.

    Because EMDR guided patients to process memories in a way that made them less distressing, some concluded EMDR-elicited memories were comparably susceptible to distortion as hypnotically-induced memories.

    This perception of EMDR at the time may also have been influenced by much initial scepticism of the therapy.

    In the early period of its popularity, EMDR proponents made excessive claims of its success, such as being able to completely resolve trauma memories in a single session, despite the lack of evidence.

    What does the evidence actually say?

    It’s difficult to test the claim that EMDR increases the likelihood of false memories because you can’t readily study this in clinical settings.

    Instead, researchers have used experimental designs in people without PTSD to determine if eye movements themselves are likely to lead to false memories. The results are mixed.

    Multiple studies have shown eye movements can lead to false memories. One study showed healthy research participants a video of a car accident. Half the sample then used eye movements. Then all participants were read an eye-witness narrative that involved false information about the video.

    This study found those who used eye movements were more susceptible to the misinformation. It seems this effect may occur because eye movements reduce the vividness and intensity of emotions in memories, thereby making them more susceptible to false memories.

    However, other laboratory-based studies have not replicated this effect. One study using the same design found using eye movements didn’t make memory more likely, reduce correct memory details, or affect the vividness or emotional intensity of the memory.

    What does this all mean?

    EMDR is one of a suite of exposure-based treatments for PTSD that involve recounting trauma memories and integrating new information about the trauma. These appear to be key in helping people resolve their traumatic stress. Although EMDR is not better than other exposure-based treatment, it is as effective as the others.

    Although some evidence points to eye movements making a person more susceptible to false memories, other studies do not find this. Importantly, these studies are not actually testing EMDR.

    There is no direct evidence that EMDR leads to false memories, just as there is no evidence that prolonged exposure or other exposure-based treatments do. Singling EMDR out as being particularly susceptible to memory distortion doesn’t appear to be supported by the scientific evidence.

    The position of legal authorities to not accept testimony following EMDR is therefore not justified and may deny trauma survivors the right to legal proceedings.


    If this article has raised issues for you, or if you’re concerned about someone you know, call Lifeline on 13 11 14. The National Sexual Assault, Family and Domestic Violence Counselling Line – 1800 RESPECT (1800 737 732) – is also available 24/7 for any Australian who has experienced family violence or sexual assault.

    Richard Bryant, Professor & Director of Traumatic Stress Clinic, UNSW Sydney

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • ‘Decision fatigue’ could be hurting your health. A nutritionist explains

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    You’re standing in a supermarket aisle, weighing up whether to buy a microwave meal or a bunch of fresh carrots.

    We all know making healthy eating choices can be tough. That’s especially true if you are hungry, or have a hungry household to feed.

    There are so many reasons for this, and many are outside our control. But one you might not be aware of is a psychological concept known as “decision fatigue”.

    So what exactly is decision fatigue? And could it help or hinder your healthy eating goals?

    Peter Dazeley/Getty

    What is decision fatigue?

    Decision fatigue, also known as choice overload, describes what happens when we make many effortful decisions over time.

    Whenever you make a decision, you use a small amount of mental energy. As that energy runs low, you tend to make worse decisions.

    This means you’re more likely to act without thinking, or simply choose what is easy or familiar. You might also find it harder to plan ahead and resist certain impulses.

    This means you might be more likely to grab a takeaway instead of the ingredients to make a meal, or default to familiar comfort foods instead of making intentional, healthy choices.

    How might it affect my eating habits?

    The average person makes hundreds of food decisions each day.

    You may think you’re just choosing a meal. But that one decision involves making many layered choices about what and how much you eat, as well as where, when and how you eat it.

    You may make these choices subconsciously or automatically. But they each require to you weigh up various factors, such as taste, costs, time, expectations and more.

    When decision fatigue sets in, you’re less likely to make thoughtful, health-focused choices. Instead, you may gravitate towards options that require less effort and offer quick rewards. You may also become more influenced by outside cues. An example of this is advertising that promotes convenient but high-calorie options such as fast food, snacks or indulgent treats.

    Having too much information can make these decisions even harder. Nutrition advice often assesses the value of foods by how much protein, fat, fibre or vitamins they contain. This way of thinking, sometimes called nutritionism, can make food choices more complex. Instead of choosing food as food, we try to calculate and juggle many numbers at once.

    Not the only factor

    Several other factors may affect your food choices.

    One is stress. One study from 2022 showed parents who experience high levels of both stress and decision fatigue found it more difficult to stick to positive food-related behaviours, such as making meals from scratch or eating together as a family.

    Another is tiredness. One 2017 study showed time of day affected meal choices. It found between mealtimes, and especially in the afternoon, people were more likely to choose the simpler default food choice than one that required more consideration. This suggests having lower blood sugar and less mental energy meant people made less considered decisions.

    How can I reduce my decision fatigue?

    Here are four tips.

    Have healthy foods on hand

    When we’re low on mental or physical energy, we usually turn to what’s easy or familiar. That’s why it’s important to have healthy food options within reach. Thankfully, this doesn’t need to be complicated. It could look like pre-cutting fruit or having some healthy frozen meals in the freezer. And research suggests removing unhealthy foods – for example from the pantry or fridge – can be just as helpful when you’re trying to make healthier food choices.

    Plan your meals

    Planning meals could help too. This may involve setting some weekend time aside to decide what meals you’ll cook and eat. That’s instead of making last-minute decisions at the supermarket or on the drive home. Meal kits and batch cooking, which both reduce the number of food-related decisions you have to make, may also reduce decision fatigue.

    Reframe your eating choices

    How you frame choices may also improve your eating habits. For example, you may be more likely to “eat a colourful meal” rather than simply telling yourself to “eat more vegetables”.

    Outsource some of the decision-making

    If you’re looking for healthy, tasty recipes, you don’t need to re-invent the wheel. You can find a wealth of free ideas on the Eat for Health, Heart Foundation and National Nutrition Foundation websites. And if making food decisions feels overwhelming, Accredited Practicing Dietitians and Registered Nutritionists can help you turn complex nutrition advice into manageable steps.

    The bottom line

    We often think eating should be simple and intuitive, but blame ourselves when it doesn’t feel that way. However, the concept of decision fatigue shows healthy eating is not just about willpower. It’s also about noticing when you’re tired, stressed or time-poor, and taking practical steps to make healthy foods the easiest option.

    Emma Beckett, Senior Lecturer, Nutrition and Food Science, Australian Catholic University

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

    Don’t Forget…

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  • Swedish Death Cleaning Made Easy for Americans – by Greta Gunnarsson

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    In Sweden, there is famously the tradition of doing much of one’s own house-clearing in advance, rather than leaving it to whoever will administrate your estate after your death.

    It’s easy to think “well, I don’t know what they’ll want, so I’ll just leave everything for them to sort out”. However, the truth is—as you’ll doubtlessly know if you’ve previously been the one responsible for administrating someone else’s estate after their death—it can be quite overwhelming.

    Reviewer’s example: when my mother died, I was the only person left to deal with it. I found myself so up to my ears in death-bureaucracy and legal requirements, that when it came to the physical stuff in her house… It was so overwhelming, I took one thing (a stuffed toy that had been mine as a child) and just abandoned everything else for the housing trust to dispose of.

    You probably don’t want that to be your legacy. So, this book guides us through deciding for ourselves how we want to be remembered, curating what will be left behind, prioritizing memories we want to last when we are gone, and honestly, eliminating the things we don’t.

    The book is, thus, half Marie Kondo and half a very specific kind of therapy.

    Of course, there’s lots we’ll keep around just because we want/need it while we’re alive, and that’s fine. We don’t have to die with an empty closet, after all. But, there’s lots we can, upon examination, get rid of now, meaning that when our kids or whoever it may be go through our things, they’re not put in a position of being unable to see the wood for the trees.

    Gunnarson talks us through the practicalities and the sentimentalities, the things we might not think of, and the things we should probably tell somebody about. And, for that matter, the things that might be better left unsaid!

    Bottom line: if you care at all about your legacy, then preparing in this way is important, and this book can help make it all a lot easier by walking us through the process.

    Click here to check out Swedish Death Cleaning Made Easy for Americans, and curate your own legacy!

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  • How Psychedelics Repair Brain Myelin!

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    We’ve written before about myelin (the protective sheath that neurons live in—basically, myelin sheaths do for neurons what telomere caps do for DNA).

    Behold: How To Rebuild Your Neurons’ Myelin Sheaths ← this is an article about phosphatidylserine’s role in that process

    The health of our myelin is important, because as well as protecting the neurons, the myelin also insulates them—remember that in essence, nerves (made of neurons) are a lot like electrical wires, and they can absolutely be shorted out, misfired, etc, and myelin is a large part of what keeps that from happening (provided everything’s working as it should).

    Consequently, demyelination is considered an issue partially responsible for the ill effects of several degenerative diseases, with multiple sclerosis (MS) being high on the list.

    So, how do psychedelics help?

    Psychedelics, myelin, and you

    Regular readers may recall our articles about psychedelics and mental health, such as:

    Taking A Trip Through The Evidence On Psychedelics

    …and also:

    Psychedelics: Yes Even Once?

    …which has to do with the lasting benefits of a single dose of a psychedelic compound. How lasting, you wonder? Well, there’s nuance to the answer, so you’ll need to read the article for that, but “a surprisingly good while”.

    Now, most recently, researchers (Dr. Mehmet Bostancıklıoğlu et al.) found that psychedelics can support long-term PTSD recovery by promoting myelin repair and (with it) reorganization of brain networks.

    Why this matters in PTSD: post-traumatic stress disorder involves not just strongly encoded unpleasant memories, but also disrupted timing and coordination across brain circuits, particularly in memory-related regions like the dentate gyrus of the hippocampus. And that’s “how it gets you”, in terms of the brain not really fully accepting that the Bad Thing™ is in the past, and that you are safe now, even if intellectually you know these things. It can sound like psychobabble or (more charitably) therapy talk, and in a way it is that latter, but there’s also some very clear neurology going on here, as this study elucidates.

    What Dr. Bostancıklıoğlu and his team found is that low repeated doses of psilocybin and 3,4-methylenedioxymethamphetamine (MDMA) caused changes in oligodendrocytes (the cells that produce myelin) and multi-omic genetic signatures that are consistent with myelin remodeling, which gave the clue that that repairing neuronal insulation (i.e., the myelination) could help stabilize healthier circuit dynamics after psychedelic treatment.

    Not liking to leave hypotheses untested, the team did find causation, not just correlation:

    • Experimenting on rats, the researchers experimentally damaged myelin, finding that the anxiolytic effects of psilocybin and MDMA disappeared, while improving myelination supported recovery, showing that intact myelin was required for behavioural improvement.
    • Next up, they blocked the serotonin 5-HT2A receptors, which prevented both behavioural benefits and myelin-related changes, showing that classic psychedelic receptor pathways are necessary for these structural effects too.
    • Lastly, they found that using anisomycin to block fear-memory formation reduced anxiety but did not repair myelin, showing that mere symptom suppression (however potentially beneficial as an end in itself) differs from the true biological recovery that this provides.

    In other words, it not only works (which we already somewhat knew, by virtue of studies such as those we talked about in our “Taking A Trip Through The Evidence On Psychedelics” article), but also, we now know how it works too.

    Which is useful, because:

    • understanding how it works helps us to help it to work better
    • understanding how it works will promote more research
    • understanding how it works will help improve accessibility*

    *because, for example, health insurers find it harder to say no, the more strongly evidence-based a treatment is, and also doctors will be quicker to sign prescriptions for things that are well-understood.

    You can read the paper in full, at: MDMA and psilocybin regulate oligodendrocyte-lineage cell numbers and anxiety-like behaviors in a rat model of fear

    Want to learn more?

    For more comprehensive brain-rebuilding advice, check out:

    Building Your Brain At Every Age ← for a more multimodal approach, because after all, why rely on just one thing?

    And for more on psychedelics specifically, you might like this book we reviewed a little while back:

    Psychedelics and Psychotherapy – Edited by Dr. Tim Read & Maria Papaspyrou

    Take care!

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