
Cannabinoid products may reduce total sleep time in adults with insomnia
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You might have heard cannabis and cannabinoid products can help people sleep. Data shows one of the top reasons people use cannabis is to help them sleep.
But there’s a dearth of high-quality research on how medicinal cannabis products actually affect sleep.
To find out more, our research team conducted a small pilot study involving 20 people. We wanted to compare how they slept after using a medicinal cannabis product, compared to a placebo.
The results of the study, published today in the Journal of Sleep Research, surprised us.
We found a single oral dose of a cannabinoid product decreased total sleep time and the time spent in REM sleep (rapid eye movement, which is when we tend to dream). We didn’t observe any change in objective alertness the day after the treatment.
Our study is small and only measured the effect of a single dose, so more research is clearly needed.
But overall, our findings suggest cannabinoids may acutely influence sleep, primarily by suppressing REM sleep, without noticeable next-day impairment.

What we did
All 20 people (16 of whom were female) involved in our study had a clinical diagnosis of insomnia disorder.
This means they reported having challenges falling asleep and/or maintaining sleep and that these disturbances impact day-to-day functioning socially, at work, or in other important areas of life.
The average age of our study participants was about 46 years.
At our lab, the study participants were interviewed by a doctor and had their medical history taken. All participants also underwent an overnight diagnostic sleep study. This was done to confirm their sleeplessness was truly insomnia and not other conditions such as sleep apnoea.
Once the participant was able to start the study, they were asked to sleep for two nights at our lab, with at least one week between those two visits.
On one of their visits, they were given a placebo.
On the other, they were given a single oral dose of a medical-grade cannabis oil containing 10 mg THC (tetrahydrocannabinol, the compound responsible for the psychoactive effects of cannabis) and 200 mg CBD (cannabidiol, which does not produce a “high”).
Using a product with a precise, known dose ensures the results are relevant to what doctors in Australia are already prescribing.
The order in which participants received either the treatment or the placebo was randomised, so they didn’t know which one they were taking.
After taking either the treatment or the placebo, they slept at our lab while wearing a special cap with 256 monitors on it. This high-density electroencephalogram or EEG allowed us to record the electrical activity of the brain while the person slept.
The next morning, after they either woke or were woken, they performed a driving simulation test around the time of their normal morning commute.
They also underwent a test that assessed their ability to stay awake in a quiet, dimly lit environment. To track their alertness throughout the day, they repeated this test four times while wearing the high-density EEG cap. This was so we could test their alertness the day after either the treatment or the placebo.
What we found
Our results were not what we expected.
We found the THC/CBD treatment decreased total sleep time by an average of 24.5 minutes. This was largely driven by a significant impact on REM sleep (the phase associated with dreaming), which not only decreased by an average of 33.9 minutes but also took significantly longer for participants to enter. The treatment also offered no benefit in helping participants stay asleep throughout the night.
Perhaps most intriguingly, this objective worsening of sleep wasn’t reflected in the participants’ own perceptions; they reported no change in their subjective sleep quality. This disconnect continued into the next day.
While participants noted feeling slightly more sleepy after the treatment, their objective alertness – measured by their ability to stay awake in a quiet, dimly lit room – was reassuringly unchanged, as was their cognitive and simulated driving performance.
This leads to a crucial question: if a single dose produces these changes, what are the cumulative effects on a person’s sleep after weeks, months, or years of nightly use?
We simply don’t have the answers yet, especially with a medical-grade cannabis product.
A growing body of research
Our findings underscore a significant gap between the widespread public perception of cannabis for sleep and the complex scientific reality. As highlighted by a review we published in the journal Current Psychiatry Reports, the evidence base remains thin.
We reviewed 21 recent studies (published between 2021 and 2024) of cannabinoids being used for insomnia, subjective sleep impairment, obstructive sleep apnoea, rapid eye movement sleep behaviour disorder, and restless legs syndrome.
We found that, despite its widespread use, there’s not enough research yet to support the use of medical cannabis to treat sleep disorders.
This is why this kind of research is so vital. It provides the first pieces of a much larger puzzle.
To give doctors and patients the clear guidance they need, there is an urgent need for adequately funded, well-designed clinical trials with larger sample sizes and longer treatment durations to truly understand the long-term impacts of medicinal cannabis on sleep and daytime functioning.
Camilla Hoyos, Senior Lecturer in the Centre for Sleep and Chronobiology, Macquarie University and Anastasia Suraev, Senior Research Fellow, Healthy Brain Ageing Program, Brain and Mind Centre, University of Sydney
This article is republished from The Conversation under a Creative Commons license. Read the original article.
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Ridged Nails: What Are They Telling You?
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Dr. Yaseen Arsalan, a Doctor of Pharmacy, has advice on the “nutraceutical” side of things:
Onychorrhexis
Sounds like the name of a dinosaur, but it’s actually the condition that creates the vertical ridges that sometimes appear on nails. It’s especially likely in the case of thinner nails, and/or certain nutritional deficiencies. Overuse of certain chemicals (including nail polish remover, hair products that get on your hands a lot, and cleaning fluids) can also cause it. It can also be worsened by various conditions, including eczema, psoriasis, hypothyroidism, anemia, and amyloidosis, but it won’t usually be outright caused by those alone.
There are two main kinds of ridges on nails:
- Vertical ridges: associated with hypothyroidism, anemia, and aging. Often an indicator of low iron.
- Horizontal ridges (Beau’s lines): caused by interrupted nail growth, brute force trauma, chemotherapy, acrylic nails, and gel nail polishes. Can also be an indicator of low zinc.
There are an assortment of medical treatments available, which Dr. Arsalan discusses in the video, but for home remedy treatment, he recommends:
- Nail-strengthening creams (look for coconut oil, shea butter, beeswax, vitamin E)
- Hydration (this is about overall hydration e.g. water intake)
- Careful nail trimming (fingernails with a curved shape and toenails straight across)
- Nail ridge filler (he recommends the brand Barrielle, for not containing formaldehyde or formalin)
- Moisturization (with cuticle oil or hand creams, because that hydration we talked about earlier is important, and we want it to stay inside the nail)
For more on those things, plus the medical treatments plus other “how to avoid this” measures, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like to read:
- The Counterintuitive Dos and Don’ts of Nail Health
- Regular Nail Polish vs Gel Nail Polish – Which is Healthier?
Take care!
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‘Emergency’ or Not, Covid Is Still Killing People. Here’s What Doctors Advise to Stay Safe.
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With around 20,000 people dying of covid in the United States since the start of October, and tens of thousands more abroad, the covid pandemic clearly isn’t over. However, the crisis response is, since the World Health Organization and the Biden administration ended their declared health emergencies last year.
Let’s not confuse the terms “pandemic” and “emergency.” As Abraar Karan, an infectious disease physician and researcher at Stanford University, said, “The pandemic is over until you are scrunched in bed, feeling terrible.”
Pandemics are defined by neither time nor severity, but rather by large numbers of ongoing infections worldwide. Emergencies are acute and declared to trigger an urgent response. Ending the official emergency shifted the responsibility for curbing covid from leaders to the public. In the United States, it meant, for example, that the government largely stopped covering the cost of covid tests and vaccines.
But the virus is still infecting people; indeed, it is surging right now.
With changes in the nature of the pandemic and the response, KFF Health News spoke with doctors and researchers about how to best handle covid, influenza, and other respiratory ailments spreading this season.
A holiday wave of sickness has ensued as expected. Covid infections have escalated nationwide in the past few weeks, with analyses of virus traces in wastewater suggesting infection rates as high as last year’s. More than 73,000 people died of covid in the U.S. in 2023, meaning the virus remains deadlier than car accidents and influenza. Still, compared with last year’s seasonal surge, this winter’s wave of covid hospitalizations has been lower and death rates less than half.
“We’re seeing outbreaks in homeless shelters and in nursing homes, but hospitals aren’t overwhelmed like they have been in the past,” said Salvador Sandoval, a doctor and health officer at the Merced County public health department in California. He attributes that welcome fact to vaccination, covid treatments like Paxlovid, and a degree of immunity from prior infections.
While a new coronavirus variant, JN.1, has spread around the world, the current vaccines and covid tests remain effective.
Other seasonal illnesses are surging, too, but rates are consistent with those of previous years. Between 9,400 and 28,000 people died from influenza from Oct. 1 to Jan. 6, estimates the Centers for Disease Control and Prevention, and millions felt so ill from the flu that they sought medical care. Cases of pneumonia — a serious condition marked by inflamed lungs that can be triggered by the flu, covid, or other infections — also predictably rose as winter set in. Researchers are now less concerned about flare-ups of pneumonia in China, Denmark, and France in November and December, because they fit cyclical patterns of the pneumonia-causing bacteria Mycoplasma pneumoniae rather than outbreaks of a dangerous new bug.
Public health researchers recommend following the CDC guidance on getting the latest covid and influenza vaccines to ward off hospitalization and death from the diseases and reduce chances of getting sick. A recent review of studies that included 614,000 people found that those who received two covid vaccines were also less likely to develop long covid; often involving fatigue, cognitive dysfunction, and joint pain, the condition is marked by the development or continuation of symptoms a few months after an infection and has been debilitating for millions of people. Another analysis found that people who had three doses of covid vaccines were much less likely to have long covid than those who were unvaccinated. (A caveat, however, is that those with three doses might have taken additional measures to avoid infections than those who chose to go without.)
It’s not too late for an influenza vaccine, either, said Helen Chu, a doctor and epidemiologist at the University of Washington in Seattle. Influenza continues to rise into the new year, especially in Southern states and California. Last season’s shot appeared to reduce adults’ risk of visits to the emergency room and urgent care by almost half and hospitalization by more than a third. Meanwhile, another seasonal illness with a fresh set of vaccines released last year, respiratory syncytial virus, appears to be waning this month.
Another powerful way to prevent covid, influenza, common colds, and other airborne infections is by wearing an N95 mask. Many researchers say they’ve returned to socializing without one but opt for the masks in crowded, indoor places when wearing one would not be particularly burdensome. Karan, for example, wears his favorite N95 masks on airplanes. And don’t forget good, old-fashioned hand-washing, which helps prevent infections as well.
If you do all that and still feel sick? Researchers say they reach for rapid covid tests. While they’ve never been perfect, they’re often quite helpful in guiding a person’s next steps.
When President Joe Biden declared the end of the public health emergency last year, many federally funded testing sites that sent samples to laboratories shut their doors. As a result, people now mainly turn to home covid tests that signal an infection within 15 minutes and cost around $6 to $8 each at many pharmacies. The trick is to use these tests correctly by taking more than one when there’s reason for concern. They miss early infections more often than tests processed in a lab, because higher levels of the coronavirus are required for detection — and the virus takes time to multiply in the body. For this reason, Karan considers other information. “If I ran into someone who turned out to be sick, and then I get symptoms a few days later,” he said, “the chance is high that I have whatever they had, even if a test is negative.”
A negative result with a rapid test might mean simply that an infection hasn’t progressed enough to be detected, that the test had expired, or that it was conducted wrong. To be sure the culprit behind symptoms like a sore throat isn’t covid, researchers suggest testing again in a day or two. It often takes about three days after symptoms start for a test to register as positive, said Karan, adding that such time estimates are based on averages and that individuals may deviate from the norm.
If a person feels healthy and wants to know their status because they were around someone with covid, Karan recommends testing two to four days after the exposure. To protect others during those uncertain days, the person can wear an N95 mask that blocks the spread of the virus. If tests remain negative five days after an exposure and the person still feels fine, Chu said, they’re unlikely to be infected — and, if they are, viral levels would be so low that they would be unlikely to pass the disease to others.
Positive tests, on the other hand, reliably flag an infection. In this case, people can ask a doctor whether they qualify for the antiviral drug Paxlovid. The pills work best when taken immediately after symptoms begin so that they slash levels of the virus before it damages the body. Some studies suggest the medicine reduces a person’s risk of long covid, too, but the evidence is mixed. Another note on tests: Don’t worry if they continue to turn out positive for longer than symptoms last; the virus may linger even if it’s no longer replicating. After roughly a week since a positive test or symptoms, studies suggest, a person is unlikely to pass the virus to others.
If covid is ruled out, Karan recommends tests for influenza because they can guide doctors on whether to prescribe an antiviral to fight it — or if instead it’s a bacterial infection, in which case antibiotics may be in order. (One new home test diagnoses covid and influenza at the same time.) Whereas antivirals and antibiotics target the source of the ailment, over-the-counter medications may soothe congestion, coughs, fevers, and other symptoms. That said, the FDA recently determined that a main ingredient in versions of Sudafed, NyQuil, and other decongestants, called phenylephrine, is ineffective.
Jobs complicate a personal approach to staying healthy. Emergency-era business closures have ended, and mandates on vaccination and wearing masks have receded across the country. Some managers take precautions to protect their staff. Chu, for example, keeps air-purifying devices around her lab, and she asks researchers to stay home when they feel sick and to test themselves for covid before returning to work after a trip.
However, occupational safety experts note that many employees face risks they cannot control because decisions on if and how to protect against outbreaks, such as through ventilation, testing, and masking, are left to employers. Notably, people with low-wage and part-time jobs — occupations disproportionately held by people of color — are often least able to control their workplace environments.
Jessica Martinez, co-executive director of the National Council for Occupational Safety and Health, said the lack of national occupational standards around airborne disease protection represents a fatal flaw in the Biden administration’s decision to relinquish its control of the pandemic.
“Every workplace needs to have a plan for reducing the threat of infectious disease,” she said. “If you only focus on the individual, you fail workers.”
KFF Health News is a national newsroom that produces in-depth journalism about health issues and is one of the core operating programs at KFF—an independent source of health policy research, polling, and journalism. Learn more about KFF.
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Breathing For Pain Relief & Core Strength (How To Reconnect Your Breath & Body)
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Dr. Amy Konvalin explains how to do it and why it works:
Take a deep breath…
A lot of people people overuse neck and shoulder “accessory” muscles due to stress, posture, and habits like mouth breathing, which leads to tension and increasingly shallow breathing. In contrast, using your diaphragm improves movement, reduces pain, supports your core, and helps calm your nervous system via the vagus nerve.
So, let’s do this in stages:
- First, diaphragmatic breathing: lie on your back to start, as this reduces strain and prevents dizziness while learning the pattern. Breathe in through your nose and let your belly rise, then breathe out through your mouth slowly but purposefully, like blowing out a candle. Let your belly expand on the inhale and fall on the exhale, using your hands for feedback if you need to.
- Next, abdominal control: allow your abdominals to relax and lengthen on the inhale, then gently contract them on the exhale to push air out. Your strongest abdominal engagement should happen at the end of the exhale when your belly is flat. Don’t flatten or move your lower back yet, and don’t lift your glutes yet either; keep your spine in a neutral position throughout.
- Next, integrating with movement: once breathing and abdominal control improve, add leg movement (for example a bridge) to train breathing during activity. Exhale, contract your abdominals, then lift your hips using your glutes, keeping control of your breathing. Breathe in as you lower yourself back down, and continue controlled breathing while moving, but do prioritize breathing quality over movement.
- Finally, back-body breathing: the diaphragm also expands your back ribs, so full breathing includes movement in both the front (belly) and back (rib cage). You can use a hands-and-knees position with a neutral spine, to better feel your back ribs expand. Start the inhale with belly expansion, then take a little more air to expand your back ribs, before exhaling with abdominal contraction. Dr. Konvalin notes that the rib motion is subtle, and so urges us to focus on the sensation rather than expecting large visible movement.
The idea of all of this is to retrain your body so diaphragmatic breathing happens all day, reducing tension and improving overall function.
For more on all of this, enjoy:
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Want to learn more?
You might like this book we reviewed a little while back:
The Oxygen Advantage – by Patrick McKeown
Take care!
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How Sugarcane Can Help Your Teeth!
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No, not by eating it (sorry!), but rather because of how it can be used medicinally:
It’s about saliva
Your teeth are sitting all day every day in a liquid, and a lot of people don’t give much thought to the effect that liquid has on dental health.
But maybe we should, because saliva helps control bacteria, neutralize acids, and maintain mineral balance, so if things go wrong with our saliva (microbiota imbalance, wrong pH, not enough saliva, etc), then we start to have problems with our gums and teeth.
We’ve written about this before, here: Make Your Saliva Better For Your Teeth
So, what’s new? Researchers (Dr. Natara Dias Gomes Da Silva et al.) have created an artificial saliva using a sugarcane-derived protein (known as “CANECPI-5” to its friends), which not only mimics, but also improves, the vital protective role of natural saliva.
How it works: the protein binds directly to enamel and forms a thin protective layer that shields your teeth from acid attacks and bacterial damage. Of its various ways of helping, the most important mechanism is that it increases enamel resistance by reducing demineralization, which is the loss of calcium and phosphate that weakens your teeth and leads to cavities.
And on the microbiota side of things, the formulation didn’t just kill bacteria; it preserved overall microbial diversity while favouring healthier, non-harmful, often helpful, species.
As for how well it works: the treatment has already been tested as a mouthwash, gel, spray, and dissolvable oral film, all of which effectively deliver the protein to your teeth, and it got results comparable to or better than standard products like chlorhexidine.
That said, combining the protein with fluoride and xylitol produced the strongest effects of all.
If you have worries about those two things, then do check out:
- Fluoride Toothpaste vs Non-Fluoride Toothpaste – Which is Healthier?
- Xylitol: Cavity Fighter Or Gut Disruptor?
Other ingredients are also being considered, for example, as Dr. Da Silva herself put it:
❝Another aspect of the project is to associate CANECPI-5 with vitamin E because this vitamin acts as a carrier, bringing the protein into contact with the tooth❞
You can find the paper itself, here: A novel artificial saliva enriched with CaneCPI-5 for irradiated head and neck cancer (HNC) patients: in vitro antimicrobial and anticaries effect
Want to learn more?
For a much deeper-dive into the topic than we have room for here, you might like this book we reviewed a while back:
The Dental Diet: The Surprising Link Between Your Teeth, Real Food, and Life-Changing Natural Health – by Dr. Steven Lin ← this pertains to a lot more than just “avoided added sugar and acidic things”, and covers such topics as the fat-soluble vitamins that are essential to teeth health, and what’s good or bad for our oral microbiome (and thus our saliva, and thus our teeth and gums), and more.
See also:
- Why Healthy Teeth May Depend On Omega-3 & Exercise
- Fish Oil Can Backfire Without This Enzyme
- Morin: Your Mouth’s New Best Friend
Finally, you might also like to read this three-part series on dental health:
- Toothpastes & Mouthwashes: Which Help And Which Harm?
- Flossing Without Flossing?
- Less Common Oral Hygiene Options ← we recommend the miswak! Not only does it clean the teeth as well as or better than traditional brushing, but also it does similarly to the protein being discussed today, and changes the composition of saliva to improve the oral microbiome, effectively turning your saliva into a biological mouthwash that kills unwanted microbes and is comfortable for the ones that should be there.
Take care!
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Fix This Silent Hip Problem Before It Destroys Your Knees
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Over-50s specialist physio Will Harlow explains:
When your hips don’t ply…
Poor hip rotation can damage the knees. This is because if hips can’t rotate, the knee may be forced to rotate, increasing the risk of ligament and meniscus injuries, neither of which are fun. Dynamic valgus (the knee falling inward during movement) is another common issue also linked to poor hip rotation.
As to why it happens in the first place: poor hip rotation can come from arthritis, but mostly it just comes from disuse. To fix this, you can improve both mobility and strength in the hip rotators through exercises such as…
- Hip windshield wipers: sit with your back supported and your knees bent at about 90°. Let your legs fall from side to side like windshield wipers, allowing one leg to go into external rotation and the other into internal rotation. Perform 20–30 reps, ideally over 1–2 minutes, and repeat a few times throughout the day.
- Seated external & internal rotation: sit comfortably in a chair and lift one leg at a time. Rotate the leg outward (external rotation) and then inward (internal rotation). Even limited movement is beneficial. Aim for 30 reps in each direction on both legs, twice a day.
- Clam exercise: lie on your side with your knees and hips bent at 90°. For the basic version, lift the top knee while keeping your feet together. For the advanced version, lift the top knee, then also lift the foot for added rotation. Do 10–20 reps per side and complete 2–3 sets depending on difficulty.
- Single-leg bridge: lie on your back with your knees bent and perform a standard bridge by lifting your hips. While holding the bridge position, lift one leg without letting your pelvis drop to engage the opposite hip. Hold each leg for 3 seconds, do 5 reps total, and complete 3 sets with about a minute of rest between rounds.
For more on each of these plus visual demonstrations, enjoy:
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Want to learn more?
You might also like:
The Secret To Better Squats: Foot, Knee, & Ankle Mobility ← if you want to go beyond just hips-and-knees, for a full lower-body mobility routine
Take care!
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The Compass of Pleasure – by Dr. David Linden
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There are a lot of books about addiction, so what sets this one apart?
Mostly, it’s that this one maintains that addiction is neither good nor bad per se—just, some behaviors and circumstances are. Behaviors and circumstances caused, directly or indirectly, by addiction.
But, Dr. Linden argues, not every addiction has to be so. Especially behavioral addictions; the rush of dopamine one gets from a good session at the gym or learning a new language, that’s not a bad thing, even if they can fundamentally be addictions too.
Similarly, we wouldn’t be here as a species without some things that rely on some of the same biochemistry as addictions; orgasms and eating food, for example. Yet, those very same urges can also inconvenience us, and in the case of foods and other substances, can harm our health.
In this book, the case is made for shifting our addictive tendencies to healthier addictions, and enough information is given to help us do so.
Bottom line: if you’d like to understand what is going on when you get waylaid by some temptation, and how to be tempted to better things, this book can give the understanding to do just that.
Click here to check out The Compass of Pleasure, and make yours work in your favor!
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