What Are “Adaptogens” Anyway? (And Other Questions Answered)

10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

It’s Q&A Day at 10almonds!

Have a question or a request? You can always hit “reply” to any of our emails, or use the feedback widget at the bottom!

In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

So, no question/request too big or small

❝I tried to use your calculator for heart health, and was unable to enter in my height or weight. Is there another way to calculate? Why will that field not populate?❞

(this is in reference to yesterday’s main feature “How Are You, Really? And How Old Is Your Heart?“)

How strange! We tested it in several desktop browsers and several mobile browsers, and were unable to find any version that didn’t work. That includes switching between metric and imperial units, per preference; both appear to work fine. Do be aware that it’ll only take numerical imput, though.

Did anyone else have this problem? Let us know! (You can reply to this email, or use the handy feedback widget at the bototm)

❝I may have missed it, but how much black pepper provides benefits?❞

So, for any new subscribers joining us today, this is about two recent main features:

As for a daily dosage of black pepper, it varies depending on the benefit you’re looking for, but:

  • 5–20mg of piperine is the dosage range used in most scientific studies we looked at
  • 10mg is a very common dosage found in many popular supplements
  • That’s the mass of piperine though, so if taking it as actual black pepper rather than as an extract, ½ teaspoon is considered sufficient to enjoy benefits.

❝I loved the health benefits of pepper. I do not like pepper. Where can I get it as a supplement?❞

You can simply buy whole black peppercorns and take a few with water as though they were tablets. Your stomach acid will do the rest. Black pepper is also good for digestion, so taking it with a meal is best.

You can buy piperine (black pepper extract) by itself as a supplement in powder form, but if you don’t like black pepper, you will probably not like this powder either. We couldn’t find it readily in capsule form.

You can buy piperine (black pepper extract) as an adjunct to other supplements, with perhaps the most common/popular being turmeric capsules that also contain 10mg (or more) piperine per capsule. Shop around if you like, but here’s one that has 15mg piperine* per capsule, for example.

*They call it “Bioperine®” but that is literally just piperine. Same goes if you see “Absorbagen™”, it’s still just piperine.

❝What do you mean when you say that something is adaptogenic?❞

Simple version: it means it helps the body adapt to stress, by adjusting the body’s natural responses. Thus, adaptogenic supplements can be contrasted with tranquilizing drugs that mask stress by brute force, for example.

Technical version: adaptogenic activity refers to improving physiological stress resilience, such as by moderating and modulating hypothalamic–pituitary–adrenal axis signaling, and/or by regulating levels of endogenic compounds involved in the cellular stress response.

Read more (technical version):

Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress-Protective Activity

Read more (simple version):

European Medicines Agency’s Reflection Paper On The Adaptogenic Concept

Enjoy!

Don’t Forget…

Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

Recommended

  • DVT Risk Management Beyond The Socks
  • Nicotine pouches are being marketed to young people on social media. But are they safe, or even legal?
    Nicotine pouches, promoted on social media, offer a discreet and flavorful alternative to vaping for young people. But are they legal in Australia?

Learn to Age Gracefully

Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:

  • Fitness Freedom for Seniors – by Jackie Jacobs

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Exercise books often assume that either we are training for the Olympics, and most likely also that we are 20 years old. This one doesn’t.

    Instead, we see a well-researched, well-organized, clearly-illustrated fitness plan with age in mind. Author Jackie Jacobs offers tips and advice for all levels, and a progressive week-by-week plan of 15-minute sessions. This way, we’re neither overdoing it nor slacking off; it’s a perfect balance.

    The exercises are aimed at “all areas”, that is to say, improving cardiovascular fitness, balance, flexibility, and strength. It also gives some supplementary advice with regard to diet and suchlike, but the workouts are the real meat of the book.

    Bottom line: if you’d like a robust, science-based exercise regime that’s tailored to seniors, this is the book for you.

    Click here to check out Fitness Freedom for Seniors, and get yours!

    Share This Post

  • Meditation for Fidgety Skeptics – by Dan Harris

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    If you already meditate regularly, this book isn’t aimed at you (though you may learn a thing or two anyway—this reviewer, who has practiced meditation for the past 30 years, learned a thing!).

    However, if you’re—as the title suggests—someone who hasn’t so far been inclined towards meditation, you could get the most out of this one. We’ll say more on this (obviously), but first, there’s one other group that may benefit from this book:

    If you have already practiced meditation, and/or already understand and want its benefits, but never really made it stick as a habit.

    Now, onto what you’ll get:

    • A fair scientific overview of meditation as an increasingly evidence-based way to reduce stress and increase both happiness and productivity
    • A good grounding in what meditation is and isn’t
    • A how-to guide for building up a consistent meditation habit that won’t get kiboshed when you have a particularly hectic day—or a cold.
    • An assortment of very common (and some less common) meditative practices to try
    • Some great auxiliary tools to build cognitive restructuring into your meditation

    We don’t usually cite other people’s reviews, but we love that one Amazon reviewer wrote:

    ❝I am 3 weeks into daily meditation practice, and I already notice that I am no longer constantly wishing for undercarriage rocket launchers while driving. I will always think your driving sucks, but I no longer wish you a violent death because of it. Yes, I live in Boston❞

    ~ J. Flaherty

    Bottom line: if you’re not already meditating daily, this is definitely a book for you. And if you are, you may learn a thing or two anyway!

    Click here to get your copy of Meditation For Fidgety Skeptics from Amazon today!

    Share This Post

  • The Dopamine Myth

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    The Dopamine Myth

    There’s a popular misconception that, since dopamine is heavily involved in addictions, it’s the cause.

    We see this most often in the context of non-chemical addictions, such as:

    • gambling
    • videogames
    • social media

    And yes, those things will promote dopamine production, and yes, that will feel good. But dopamine isn’t the problem.

    Myth: The Dopamine Detox

    There’s a trend we’ve mentioned before (it got a video segment a few Fridays back) about the idea of a “dopamine detox“, and how unscientific the idea is.

    For a start…

    • You cannot detox from dopamine, because dopamine is not a toxin
    • You cannot abstain from dopamine, because your brain regulates your dopamine levels to keep them correct*
    • If you could abstain from dopamine (and did), you would die, horribly.

    *unless you have a serious mental illness, for example:

    • forms of schizophrenia and/or psychosis that involve too much dopamine, or
    • forms of depression and/or neurodegenerative diseases such as Parkinson’s (and several kinds of dementia) in which you have too little dopamine
    • bipolar disorder in which dopamine levels can swing too far each way

    See also: Dopamine fasting: misunderstanding science spawns a maladaptive fad

    Myth: Dopamine is all about pleasure

    Dopamine is a pleasure-giving neurotransmitter, but it serves more purposes than that! It also plays a central role in many neurological processes, including:

    • Motivation
    • Learning and memory
    • Motor functions
    • Language faculties
    • Linear task processing

    Note for example how someone taking dopaminergic drugs (prescription or otherwise; could be anything from modafinil to cocaine) is not blissed out… They’re probably in a good mood, sure, but they’re focused, organized, quick-thinking, and so forth! This is not an ad for cocaine; cocaine is very bad for the health. But you see the features? So, what if we could have a little more dopamine… healthily?

    Dopamine—à la carte

    Let’s look at the examples we gave earlier of non-chemical addictions that are dopaminergic in nature:

    • gambling
    • videogames
    • social media

    They’re not actually that rewarding, are they?

    • Gamblers lose more than they win
    • Gamers cease to care about a game once they have won
    • Social media more often results in “doomscrolling”

    This is because what prompts the most dopamine is actually the anticipation of reward… not the thing itself, whose reward-pleasure is very fleeting. Nobody looks back at an hour of doomscrolling and thinks “well, that was fun; I’m glad I did that”.

    See the science: Liking, Wanting and the Incentive-Sensitization Theory of Addiction

    But what if we anticipated a reward from things that are not deleterious to health and productivity? Things that are neutral, or even good for us?

    Examples of this include:

    • Sex! (remember though, it’s not a race to the finish-line)
    • Good, nourishing food (bonus: some foods boost dopamine production nutritionally)
    • Exercise/sport (also prompts release of endorphins, win/win!)
    • Gamified learning apps (e.g. Duolingo)
    • Gamified health/productivity apps (anything with bells and whistles and things that go “ding” and measure streaks etc)

    Want to know more?

    That’s all we have time for today, but you might want to check out:

    10 Best Ways to Increase Dopamine Levels Naturally ← Science-based and well-sourced article!

    Share This Post

Related Posts

  • DVT Risk Management Beyond The Socks
  • A Supplement To Rival St. John’s Wort Against Depression

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Do You Feel The SAMe?

    S-Adeonsyl-L-Methionone (SAMe) is a chemical found naturally in the body, and/but enjoyed widely as a supplement. The main reasons people take it are:

    • Improve mood (antidepressant effect)
    • Improve joints (reduce osteoarthritis symptoms)
    • Improve liver (detoxifying effect)

    Let’s see what the science says for each of those claims…

    Does it improve mood?

    It seems to perform comparably to St. John’s Wort (which is good; it performs comparably to Prozac).

    Best of all, it does this with fewer contraindications (St. John’s Wort has so many contraindications).

    Here’s how they stack up:

    St. John’s wort and S-Adenosyl Methionine as “natural” alternatives to conventional antidepressants in the era of the suicidality boxed warning: what is the evidence for clinically relevant benefit?

    This looks very promising, though it’d be nice to see a larger body of research, to be sure.

    Does it reduce osteoarthritis symptoms?

    The good news: it performs comparably to ibuprofen, with fewer side effects!

    The bad news: it also performs comparably to placebo!

    Read into that what you will about ibuprofen’s usefulness vs OA symptoms.

    Read all about it:

    S-Adenosylmethionine for osteoarthritis of the knee or hip

    If you were hoping for something for OA or similar symptoms, you might like our previous main features:

    Does it help against liver disease?

    According to adverts for SAMe: absolutely!

    According to science: we don’t know

    The science for this is so weak that it’d be unworthy of mention if it weren’t for the fact that SAMe is so widely sold as good against hepatotoxicity.

    To be clear: maybe it really is great! Science hasn’t yet disproved its usefulness either.

    It is popularly assumed to be beneficial due to there being an association between lower levels of SAMe in the body (remember, it is also produced inside our bodies) and development of liver disease, especially cholestasis.

    Here’s an example of what pretty much every study we found was like (inconclusive research based mostly on mice):

    S-adenosylmethionine in liver health, injury, and cancer

    For other options for liver health, consider:

    How To Unfatty A Fatty Liver

    Is it safe?

    Safety trials have been done ranging from 3 months to 2 years, with no serious side effects coming to light. So, it appears quite safe.

    That said, as with anything, there are contraindications, such as:

    • if you have bipolar disorder, skip this unless directed by your health care provider, because it may worsen the symptoms of mania
    • if you are on SSRIs or other serotonergic drugs, it may interact with those
    • if you are immunocompromised, you might want to skip it can increase the risk of P. carinii growth in such cases

    As always, do speak with your doctor/pharmacist for personalized advice.

    Summary

    SAMe’s evidence-based qualities seem to stack up as follows:

    • Against depression: good
    • Against osteoarthritis: weak
    • Against liver disease: unknown

    As for safety, it has been found quite safe for most people.

    Where can I get it?

    We don’t sell it, but here is an example product on Amazon, for your convenience

    Enjoy!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:

  • Apple Cider Vinegar vs Apple Cider Vinegar Gummies – Which is Healthier?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our Verdict

    When comparing apple cider vinegar (bottled) to apple cider vinegar (gummies), we picked the bottled.

    Why?

    There are several reasons!

    The first reason is about dosage. For example, the sample we picked for apple cider vinegar gummies, boasts:

    2 daily chewable gummies deliver 800 mg of Apple Cider Vinegar a day, equivalent to a teaspoon of liquid apple cider vinegar

    That sounds good until you note that it’s recommended to take 1–2 tablespoons (not teaspoons) of apple vinegar. So this would need more like 4–8 gummies to make the dose. Suddenly, either that bottle of gummies is running out quickly, or you’re just not taking a meaningful dose and your benefits will likely not exceed placebo.

    The other is reason about sugar. Most apple cider vinegar gummies are made with some kind of sugar syrup, often even high-fructose corn syrup, which is one of the least healthy foodstuffs (in the loosest sense of the word “foodstuffs”) known to science.

    The specific brand we picked today was the best we can find; it used maltitol syrup.

    Maltitol syrup, a corn derivative (and technically a sugar alcohol), has a Glycemic Index of 52, so it does raise blood sugars but not as much as sucrose would. However (and somewhat counterproductive to taking apple cider vinegar for gut health) it can cause digestive problems for many people.

    And remember, you’re taking 4–8 gummies, so this is amounting to several tablespoons of the syrup by now.

    On the flipside, apple cider vinegar itself has two main drawbacks, but they’re much less troublesome issues:

    • many people don’t like the taste
    • its acidic nature is not good for teeth

    To this the common advice for both is to dilute it with water, thus diluting the taste and the acidity.

    (this writer shoots hers from a shot glass, thus not bathing the teeth since it passes them “without touching the sides”; as for the taste, well, I find it invigorating—I do chase it with water, though to be sure of not leaving vinegar in my mouth)

    Want to check them out for yourself?

    Here they are:

    Apple cider vinegar | Apple cider vinegar gummies

    Want to know more about apple cider vinegar?

    Check out:

    Take care!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails:

  • Wasting Your Vitamins?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Are you flushing away your vitamins?

    Most likely…but you don’t have to.

    We all know what a wasteful expense supplements can sometimes be, but you can optimise your intake to get more bang for your buck!

    Top Tips for Getting Your Money’s Worth:

    1. Liquids are better than tablets—the body can’t absorb nutrients from tablets anywhere as easily as it can from liquids, with some saying as low as a 50% absorption rate for tablets, so if your supplement can come in drinkable form, take it that way!
    2. Capsules are better than tablets—capsules, depending on the kind, contain either a powder (true capsules) or a liquid (softgels). Once the capsule/softgel is broken down in the stomach, it releases its contents, which will now be absorbed as though you took it as a drink.
    3. Stay hydrated—on that note, your body can only make use of nutrients that it can easily transport, and if you’re dehydrated, the process is sluggish! Having a big glass of water with your supplements will go a long way to helping your body get them where they’re needed.
    4. Take with black pepper—studies disagree on exactly how much black pepper improves absorption of nutrients. Some say it improves it by 50%, others say as much as 7x better. The truth is probably that it varies from one nutrient to the next, but what is (almost) universally accepted is that black pepper helps you absorb many nutrients you take orally.
    5. Take with a meal—bonus if you seasoned it with black pepper! But also: many nutrients are best absorbed alongside food, and many are specifically fat-soluble (so you want to take a little fat around the same time for maximum absorption)
    6. Consider split doses—a lot of nutrients are best absorbed when spread out a bit. Why? Your body can often only absorb so much at once, and what it couldn’t absorb can, depending on the nutrient, pass right through you. So better to space out the doses—breakfast and dinner make for great times to take them.
    7. Consider cycling—no, not the two-wheeled kind, though feel free to do that too! What cycling means when it comes to supplements is to understand that your body can build a tolerance to some supplements, so you’ll get gradually less effect for the same dose. Combat this by scheduling a break—five days on, two days off is a common schedule—allowing your body to optimise itself in the process!
    8. Check Medications—and, as is always safe, make sure you check whether any medications you take can interrupt your supplement absorption!

    Don’t Forget…

    Did you arrive here from our newsletter? Don’t forget to return to the email to continue learning!

    Learn to Age Gracefully

    Join the 98k+ American women taking control of their health & aging with our 100% free (and fun!) daily emails: