The Cough Doctor

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The Cough Doctor

This is Dr. Peter Small, who worked in epidemiology since the beginning of HIV epidemic. He became a pioneer in the field of molecular epidemiology. As such, his work was a guiding beacon for the public health response to the resurgence of tuberculosis. He’s travelled the world spending years in various institutions studying all manner of respiratory illnesses…. These have ranged from tuberculosis to pneumonia to lung cancer and (back to epidemiology) Covid-19.

He’s now the Chief Medical Officer at…

Hyfe

Hyfe, a medical AI company, was founded in 2020. Its objective: to build acoustic tools for respiratory diagnostics and monitoring.

In other words: it records coughs and collects data about coughing.

❝It’s ironic how much people focus on counting steps while ignoring cough, which is far more consequential. Hyfe is a science-driven company with the technology to make cough count. Particularly now, with increased awareness of cough and the rapid growth of digital health driven by Covid-19, this technology can improve the lives of patients, the care provided by doctors, and the efficiency of health systems.❞

~ Dr. Peter Small, CMO, Hyfe

How does it do it?

Hyfe’s AI monitors the number of times a person coughs and the sound of the cough through any smartphone or other smart device.

This data collected over time provides increasingly more reliable information than a single visit to the doctor! By constantly listening and analyzing, it can detect patterns that might otherwise go unnoticed.

How big is this “big data” effort?

Hyfe maintains the largest cough dataset in the world. This means it can compare the sound of a patient’s cough with more than 400 million cough-like sounds from 83 countries across all continents.

The human brain doesn’t handle big numbers well. So, just to illustrate: if the average cough is 1 second long, that means it’d take more than 12 years to listen to them all.

Hyfe, meanwhile, can:

  • listen to many things simultaneously
  • index them all against user and location,
  • use its ever-growing neural net to detect and illustrate patterns.

It’s so attentive, that it can learn to distinguish between different people’s coughs in the same household.

❝Companies like Google Health see even basic information such as getting an accurate count of the number of times a person coughs a day as a useful resource, and part of a larger need to collect and chronicle more health information to refine the way doctors diagnose disease and manage treatments in the future.❞

~ Time Magazine

What are the public health implications?

The most obvious application is to note when there’s a spike in coughing, and see how such spikes grow and spread (if they do), to inform of contagion risks.

Another is to cross-reference it with data about local environmental allergens. Knowing how things like pollution and even pollen affect individuals differently could be helpful in identifying (and managing) chronic conditions like asthma.

What are the private health implications?

❝It’s going to transform the whole clinical approach for this common and chronic symptom. Patients will come in, have the data on how much they are coughing, and the physician can suggest a treatment based on that information to see if it makes the coughs better❞

~ Dr. Peter Small

Dr. Small’s colleague Dr. Cai, speaking for Google Health on this project, sees even more utility for diagnostics:

❝When I was in medical school, never ever did they teach us that we could listen to somebody cough and identify whether that person has TB (tuberculosis), COPD, or a tumor. But I keep seeing more and more studies of people coughing into a microphone, and an algorithm can detect whether somebody has TB with 95% specificity and sensitivity, or if someone has pneumonia or an exacerbation of COPD❞

~ Dr. Lawrence Cai

And the privacy implications?

Perhaps you don’t quite fancy the idea of not being able to cough without Google knowing about it. Hyfe’s software is currently opt-in, but…

If you cough near someone else’s Hyfe app, their app will recognize you’re not the app’s user, and start building a profile for you. Of course, that won’t be linked to your name, email address, or other IDs, as it would if you were the app’s user.

Hyfe will ask to connect to your social media, to collect more information about you and your friends.

Whether you’d like to try this or perhaps you’re just curious to learn more about this fascinating project, you can check out:

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  • Having an x-ray to diagnose knee arthritis might make you more likely to consider potentially unnecessary surgery

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    Osteoarthritis is a leading cause of chronic pain and disability, affecting more than two million Australians.

    Routine x-rays aren’t recommended to diagnose the condition. Instead, GPs can make a diagnosis based on symptoms and medical history.

    Yet nearly half of new patients with knee osteoarthritis who visit a GP in Australia are referred for imaging. Osteoarthritis imaging costs the health system A$104.7 million each year.

    Our new study shows using x-rays to diagnose knee osteoarthritis can affect how a person thinks about their knee pain – and can prompt them to consider potentially unnecessary knee replacement surgery.

    pikselstock/Shutterstock

    What happens when you get osteoarthritis?

    Osteoarthritis arises from joint changes and the joint working extra hard to repair itself. It affects the entire joint, including the bones, cartilage, ligaments and muscles.

    It is most common in older adults, people with a high body weight and those with a history of knee injury.

    Many people with knee osteoarthritis experience persistent pain and have difficulties with everyday activities such as walking and climbing stairs.

    How is it treated?

    In 2021–22, more than 53,000 Australians had knee replacement surgery for osteoarthritis.

    Hospital services for osteoarthritis, primarily driven by joint replacement surgery, cost $3.7 billion in 2020–21.

    While joint replacement surgery is often viewed as inevitable for osteoarthritis, it should only be considered for those with severe symptoms who have already tried appropriate non-surgical treatments. Surgery carries the risk of serious adverse events, such as blood clot or infection, and not everyone makes a full recovery.

    Most people with knee osteoarthritis can manage it effectively with:

    • education and self-management
    • exercise and physical activity
    • weight management (if necessary)
    • medicines for pain relief (such as paracetamol and non-steroidal anti-inflammatory drugs).

    Debunking a common misconception

    A common misconception is that osteoarthritis is caused by “wear and tear”.

    However, research shows the extent of structural changes seen in a joint on an x-ray does not reflect the level of pain or disability a person experiences, nor does it predict how symptoms will change.

    Some people with minimal joint changes have very bad symptoms, while others with more joint changes have only mild symptoms. This is why routine x-rays aren’t recommended for diagnosing knee osteoarthritis or guiding treatment decisions.

    Instead, guidelines recommend a “clinical diagnosis” based on a person’s age (being 45 years or over) and symptoms: experiencing joint pain with activity and, in the morning, having no joint-stiffness or stiffness that lasts less than 30 minutes.

    Despite this, many health professionals in Australia continue to use x-rays to diagnose knee osteoarthritis. And many people with osteoarthritis still expect or want them.

    What did our study investigate?

    Our study aimed to find out if using x-rays to diagnose knee osteoarthritis affects a person’s beliefs about osteoarthritis management, compared to a getting a clinical diagnosis without x-rays.

    We recruited 617 people from across Australia and randomly assigned them to watch one of three videos. Each video showed a hypothetical consultation with a general practitioner about knee pain.

    Woman descends steps
    People with knee osteoarthritis can have difficulties getting down stairs. beeboys/Shutterstock

    One group received a clinical diagnosis of knee osteoarthritis based on age and symptoms, without being sent for an x-ray.

    The other two groups had x-rays to determine their diagnosis (the doctor showed one group their x-ray images and not the other).

    After watching their assigned video, participants completed a survey about their beliefs about osteoarthritis management.

    What did we find?

    People who received an x-ray-based diagnosis and were shown their x-ray images had a 36% higher perceived need for knee replacement surgery than those who received a clinical diagnosis (without x-ray).

    They also believed exercise and physical activity could be more harmful to their joint, were more worried about their condition worsening, and were more fearful of movement.

    Interestingly, people were slightly more satisfied with an x-ray-based diagnosis than a clinical diagnosis.

    This may reflect the common misconception that osteoarthritis is caused by “wear and tear” and an assumption that the “damage” inside the joint needs to be seen to guide treatment.

    What does this mean for people with osteoarthritis?

    Our findings show why it’s important to avoid unnecessary x-rays when diagnosing knee osteoarthritis.

    While changing clinical practice can be challenging, reducing unnecessary x-rays could help ease patient anxiety, prevent unnecessary concern about joint damage, and reduce demand for costly and potentially unnecessary joint replacement surgery.

    It could also help reduce exposure to medical radiation and lower health-care costs.

    Previous research in osteoarthritis, as well as back and shoulder pain, similarly shows that when health professionals focus on joint “wear and tear” it can make patients more anxious about their condition and concerned about damaging their joints.

    If you have knee osteoarthritis, know that routine x-rays aren’t needed for diagnosis or to determine the best treatment for you. Getting an x-ray can make you more concerned and more open to surgery. But there are a range of non-surgical options that could reduce pain, improve mobility and are less invasive.

    Belinda Lawford, Senior Research Fellow in Physiotherapy, The University of Melbourne; Kim Bennell, Professor of Physiotherapy, The University of Melbourne; Rana Hinman, Professor in Physiotherapy, The University of Melbourne, and Travis Haber, Postdoctoral Research Fellow in Physiotherapy, The University of Melbourne

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Gut-Healthy Labneh Orecchiette

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    Labneh (a sort of yogurt-cheese made from strained yogurt) is a great probiotic, and there’s plenty of resistant starch in this dish too, from how we cook, cool, and reheat the pasta. Add to this the lycopene from the tomatoes, the ergothioneine from the mushrooms, and the healthful properties of the garlic, black pepper, and red chili, and we have a very healthy dish!

    You will need

    • 10 oz labneh (if you can’t buy it locally, you can make your own by straining Greek yogurt through a muslin cloth, suspended over a bowl to catch the water that drips out, overnight—and yes, plant-based is also fine if you are vegan, and the gut benefits are similar because unlike vegan cheese, vegan yogurt is still fermented)
    • 6 oz wholegrain orecchiette (or other pasta, but this shape works well for this sauce)
    • ¼ bulb garlic, grated
    • Juice of ½ lemon
    • Large handful chopped parsley
    • Large handful chopped dill
    • 9 oz cherry tomatoes, halved
    • 9 oz mushrooms (your choice what kind), sliced (unless you went for shiitake or similar, which don’t need it due to already being very thin)
    • 2 tsp black pepper, coarse ground
    • 1 tsp red chili flakes
    • ¼ tsp MSG or ½ tsp low-sodium salt
    • Extra virgin olive oil

    Method

    (we suggest you read everything at least once before doing anything)

    1) Cook the pasta as you normally would. Drain, and rinse with cold water. Set aside.

    2) Combine the labneh with the garlic, black pepper, dill, parsley, and lemon juice, in a large bowl. Set aside.

    3) Heat a little olive oil in a skillet; add the chili flakes, followed by the mushrooms. Cook until soft and browned, then add the tomatoes and fry for a further 1 minute—we want the tomatoes to be blistered, but not broken down. Stir in the MSG/salt, and take off the heat.

    4) Refresh the pasta by passing a kettle of boiling water through it in a colander, then add the hot pasta to the bowl of labneh sauce, stirring to coat thoroughly.

    5) Serve, spooning the mushrooms and tomatoes over the labneh pasta.

    Enjoy!

    Want to learn more?

    For those interested in some of the science of what we have going on today:

    Take care!

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  • Healthy Recipes When There Are A Lot Of Restrictions

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s Q&A Day at 10almonds!

    Have a question or a request? We love to hear from you!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small 😎

    ❝I need to cook for a family event and the combined dietary restrictions are: vegetarian, no lactose, no gluten, no nuts, including peanuts and coconuts, no discernible carbs, including lentils and chickpeas, no garlic or onions, no cabbage, no soup, and it can’t be remotely spicy. The nut allergy is of course absolute and we are vegetarian, the other things may be slightly negotiable but I’d like a stress-free dinner. Ideas?❞

    That is indeed quite restrictive! But a challenge is (almost) always fun.

    To answer generally first: one approach is to do buffet-style dining, with many small dishes. While nuts will still need to be absent, because of the nature of nut allergies, the rest can just be skipped on a per-person basis.

    But, let’s see what we can do with a one-dish-fits-all approach!

    The biggest challenge seems to be getting protein and flavor. Protein options are more limited without meat, lactose, or legumes, and flavor requires some attention without being able to rely on spices.

    To give a sample à la carte menu… With these things in mind, we’ve selected three of our recipes from the recipes section of our site, that will require only minor modifications:

    1) Invigorating Sabzi Khordan: skip the walnuts and either partition or omit the scallions, and ensure the cheese is lactose-free (most supermarkets stock lactose-free cheeses, nowadays).

    With regard to the flatbreads, you can either skip, or use our gluten-free Healthy Homemade Flatbreads recipe, though it does use chickpea flour and quinoa flour, so the “no discernible carbs” person(s) might still want to skip them. If it’s not an issue on the carbs front, then you might also consider, in lieu of one of the more traditional cheeses, using our High-Protein Paneer recipe which, being vegan, is naturally lactose-free. Also, which is not traditional but would work fine, you might want to add cold hard-boiled halved eggs, since the next course will be light on protein:

    2) Speedy Easy Ratatouille: skip the red chili and garlic; that’s all for this one!

    3) Black Forest Chia Pudding: the glycemic index of this should hopefully be sufficient to placate the “no discernible carbs” person(s), but if it’s not, we probably don’t have a keto-friendlier dessert than this. And obviously, when it comes to the garnish of “a few almonds, and/or berries, and/or cherries and/or cacao nibs”, don’t choose the almonds.

    Want to know more?

    For any who might be curious:

    Gluten: What’s The Truth? ← this also discusses the differences between an allergy/intolerance/sensitivity—it’s more than just a matter of severity!

    Take care!

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    I Know How She Does It: How Successful Women Make The Most of Their Time

    This is Laura Vanderkam, author of “Tranquility By Tuesday” (amongst other books). Her “thing” is spending more time on what’s important, and less on what isn’t. Sounds simple, but she’s made a career out of it, so condensed here for you are…

    Laura’s 7 Keys To Productivity

    Key One: Plan your weeks on Fridays

    You don’t want your Monday morning to be a “James Bond intro” (where everything is already in action and you’re just along for the ride, trying to figure out what’s going on). So, take some time last thing each Friday, to plan ahead for the following week!

    Key Two: Measure what matters

    Whatever that means to you. Laura tracks her use of time in half-hour blocks, and likes keeping track of streaks. For her, that means running daily and keeping a log of it. She also keeps track of the books she reads. For someone else it could be music practice, or a Duolingo streak, or eating fruit each day.

    On which note…

    “Dr. Greger’s Daily Dozen” is simpler than most nutrition trackers (where you must search for everything you eat, or scan barcodes for all ingredients).

    Instead, it keeps track of whether you are having certain key health-giving foods often enough to maintain good health.

    We might feature his method in a future edition of 10almonds, but for now, check the app out for yourself here:

    Get Dr. Greger’s Daily Dozen on iOS / Get Dr. Greger’s Daily Dozen on Android

    Dr. Greger’s Daily Dozen @ Nutrition Facts

    Key Three: Figure out 2–3 “anchor” events for the weekend

    Otherwise, it can become a bit of a haze and on Monday you find yourself thinking “where did the weekend go?”. So, plan some stuff! It doesn’t have to be anything out-of-this-world, just something that you can look forward to in advance and remember afterwards. It could be a meal out with your family, or a session doing some gardening, or a romantic night in with your partner. Whatever makes your life “living” and not passing you by!

    Key Four: Tackle the toughest work first

    You’ve probably heard about “swallowing frogs”. If not, there are various versions, usually attributed to Mark Twain.

    Here’s one:

    “If it’s your job to eat a frog, it’s best to do it first thing in the morning. And if it’s your job to eat two frogs, it’s best to eat the biggest one first.”

    Top Productivity App “ToDoist” has an option for this, by the way!

    ToDoist.com/productivity-methods/eat-the-frog

    ToDoist

    Laura’s key advice here is: get the hard stuff done now! Before you get distracted or tired and postpone it to tomorrow (and then lather rinse repeat, so it never gets done)

    10almonds Tip:

    “But what if something’s really important but not as pressing as some less important, but more urgent tasks?”

    Simple!

    Set a timer (we love the Pomodoro method, by the way) and do one burst of the important-but-not-urgent task first. Then you can get to the more urgent stuff.

    Repeat each day until the important-but-not-urgent task is done!

    The 10almonds Team

    Key Five: Use bits of time well

    If, like many of us, you’ve a neverending “to read” list, use the 5–10 minute breaks that get enforced upon us periodically through the day!

    • Use those few minutes before a meeting/phonecall!
    • Use the time you spend waiting for public transport or riding on it!
    • Use the time you spent waiting for a family member to finish doing a thing!

    All those 5–10 minute bits soon add up… You might as well spend that time reading something you know will add value to your life, rather than browsing social media, for example.

    Key Six: Make very short daily to-do lists

    By “short”, Laura considers this “under 10 items”. Do this as the last part of your working day, ready for tomorrow. Not at bedtime! Bedtime is for winding down, not winding up

    Key Seven: Have a bedtime

    Laura shoots for 10:30pm, but whatever works for you and your morning responsibilities. Your morning responsibilities aren’t tied to a specific time? Lucky you, but try to keep a bedtime anyway. Otherwise, your daily rhythm can end up sliding around the clock, especially if you work from home!

    Want more from Laura Vanderkam? Start Here!

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  • DVT Risk Management Beyond The Socks

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s Q&A Day at 10almonds!

    Have a question or a request? We love to hear from you!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    ❝I know I am at higher risk of DVT after having hip surgery, any advice beside compression stockings?❞

    First of all, a swift and easy recovery to you!

    Surgery indeed increases the risk of deep vein thrombosis (henceforth: DVT), and hip or knee surgery especially so, for obvious reasons.

    There are other risk factors you can’t control, like genetics (family history of DVT as an indicator) and age, but there are some that you can, including:

    • smoking (so, ideally don’t; do speak to your doctor before quitting though, in case withdrawal might be temporarily worse for you than smoking)
    • obesity (so, losing weight is good if overweight, but if this is going to happen, it’ll mostly happen in the kitchen not the gym, which may be a relief as you’re probably not the very most up for exercise at present)
    • sedentariness (so, while you’re probably not running marathons right now, please do try to keep moving, even if only gently)

    Beyond that, yes compression socks, but also frequent gentle massage can help a lot to avoid clots forming.

    Also, no surprises, a healthy diet will help, especially one that’s good for general heart health. Check out for example the Mediterranean DASH diet:

    Four Ways To Upgrade The Mediterranean Diet

    Also, obviously, speak with your doctor/pharmacist if you haven’t already about possible medications, including checking whether any of your current medications increase the risk and could be swapped for something that doesn’t.

    Take care!

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  • Tourette’s Syndrome Treatment Options

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s Q&A Day at 10almonds!

    Have a question or a request? You can always hit “reply” to any of our emails, or use the feedback widget at the bottom!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    ❝Is there anything special that might help someone with Tourette’s syndrome?❞

    There are of course a lot of different manifestations of Tourette’s syndrome, and some people’s tics may be far more problematic to themselves and/or others, while some may be quite mild and just something to work around.

    It’s an interesting topic for sure, so we’ll perhaps do a main feature (probably also covering the related-and-sometimes-overlapping OCD umbrella rather than making it hyperspecific to Tourette’s), but meanwhile, you might consider some of these options:

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