What’s the difference between ‘strep throat’ and a sore throat? We’re developing a vaccine for one of them

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What’s the difference? is a new editorial product that explains the similarities and differences between commonly confused health and medical terms, and why they matter.


It’s the time of the year for coughs, colds and sore throats. So you might have heard people talk about having a “strep throat”.

But what is that? Is it just a bad sore throat that goes away by itself in a day or two? Should you be worried?

Here’s what we know about the similarities and differences between strep throat and a sore throat, and why they matter.

Prostock-studio/Shutterstock

How are they similar?

It’s difficult to tell the difference between a sore throat and strep throat as they look and feel similar.

People usually have a fever, a bright red throat and sometimes painful lumps in the neck (swollen lymph nodes). A throat swab can help diagnose strep throat, but the results can take a few days.

Thankfully, both types of sore throat usually get better by themselves.

How are they different?

Most sore throats are caused by viruses such as common cold viruses, the flu (influenza virus), or the virus that causes glandular fever (Epstein-Barr virus).

These viral sore throats can occur at any age. Antibiotics don’t work against viruses so if you have a viral sore throat, you won’t get better faster if you take antibiotics. You might even have some unwanted antibiotic side-effects.

But strep throat is caused by Streptococcus pyogenes bacteria, also known as strep A. Strep throat is most common in school-aged children, but can affect other age groups. In some cases, you may need antibiotics to avoid some rare but serious complications.

In fact, the potential for complications is one key difference between a viral sore throat and strep throat.

Generally, a viral sore throat is very unlikely to cause complications (one exception is those caused by Epstein-Barr virus which has been associated with illnesses such as chronic fatigue syndrome, multiple sclerosis and certain cancers).

But strep A can cause invasive disease, a rare but serious complication. This is when bacteria living somewhere on the body (usually the skin or throat) get into another part of the body where there shouldn’t be bacteria, such as the bloodstream. This can make people extremely sick.

Invasive strep A infections and deaths have been rising in recent years around the world, especially in young children and older adults. This may be due to a number of factors such as increased social mixing at this stage of the COVID pandemic and an increase in circulating common cold viruses. But overall the reasons behind the increase in invasive strep A infections are not clear.

Another rare but serious side effect of strep A is autoimmune disease. This is when the body’s immune system makes antibodies that react against its own cells.

The most common example is rheumatic heart disease. This is when the body’s immune system damages the heart valves a few weeks or months after a strep throat or skin infection.

Around the world more than 40 million people live with rheumatic heart disease and more than 300,000 die from its complications every year, mostly in developing countries.

However, parts of Australia have some of the highest rates of rheumatic heart disease in the world. More than 5,300 Indigenous Australians live with it.

Streptococcus pyogenes
Strep throat is caused by Streptococcus bacteria and can be treated with antibiotics if needed. Kateryna Kon/Shutterstock

Why do some people get sicker than others?

We know strep A infections and rheumatic heart disease are more common in low socioeconomic communities where poverty and overcrowding lead to increased strep A transmission and disease.

However, we don’t fully understand why some people only get a mild infection with strep throat while others get very sick with invasive disease.

We also don’t understand why some people get rheumatic heart disease after strep A infections when most others don’t. Our research team is trying to find out.

How about a vaccine for strep A?

There is no strep A vaccine but many groups in Australia, New Zealand and worldwide are working towards one.

For instance, Murdoch Children’s Research Institute and Telethon Kids Institute have formed the Australian Strep A Vaccine Initiative to develop strep A vaccines. There’s also a global consortium working towards the same goal.

Companies such as Vaxcyte and GlaxoSmithKline have also been developing strep A vaccines.

What if I have a sore throat?

Most sore throats will get better by themselves. But if yours doesn’t get better in a few days or you have ongoing fever, see your GP.

Your GP can examine you, consider running some tests and help you decide if you need antibiotics.

Kim Davis, General paediatrician and paediatric infectious diseases specialist, Murdoch Children’s Research Institute; Alma Fulurija, Immunologist and the Australian Strep A Vaccine Initiative project lead, Telethon Kids Institute, and Myra Hardy, Postdoctoral Researcher, Infection, Immunity and Global Health, Murdoch Children’s Research Institute

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Mythbusting The Big O

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    “Early To Bed…”

    In yesterday’s newsletter, we asked you for your (health-related) views on orgasms.

    But what does the science say?

    Orgasms are essential to good health: True or False?

    False, in the most literal sense. One certainly won’t die without them. Anorgasmia (the inability to orgasm) is a condition that affects many postmenopausal women, some younger women, and some men. And importantly, it isn’t fatal—just generally considered unfortunate:

    Anorgasmia Might Explain Why You’re Not Orgasming When You Want To

    That article focuses on women; here’s a paper focusing on men:

    Delayed Orgasm and Anorgasmia

    Orgasms are good for the health, but marginally: True or False?

    True! They have a wide array of benefits, depending on various factors (including, of course, one’s own sex). That said, the benefits are so marginal that we don’t have a flock of studies to cite, and are reduced to pop-science sources that verbally cite studies that are, alas, nowhere to be found, for example:

    Doubtlessly the studies do exist, but are sparse enough that finding them is a nightmare as the keywords for them will bring up a lot of studies about orgasms and health that aren’t answering the above question (usually: health’s affect on orgasms, rather than the other way around).

    There is some good science for post-menopausal women, though! Here it is:

    Misconceptions About Sexual Health in Older Women

    (if you have the time to read this, this also covers many very avoidable things that can disrupt sexual function, in ways that people will errantly chalk up to old age, not knowing that they are missing out needlessly)

    Orgasms are good or bad, depending on being male or female: True or False

    False, broadly. The health benefits are extant and marginal for almost everyone, as indicated above.

    What’s that “almost” about, then?

    There are a very few* people (usually men) for whom it doesn’t go well. In such cases, they have a chronic and lifelong problem whereby orgasm is followed by 2–7 days of flu-like and allergic symptoms. Little is known about it, but it appears to be some sort of autoimmune disorder.

    Read more: Post-orgasmic illness syndrome: history and current perspectives

    *It’s hard to say for sure how few though, as it is surely under-reported and thus under-diagnosed; likely even misdiagnosed if the patient doesn’t realize that orgasms are the trigger for such episodes, and the doctor doesn’t think to ask. Instead, they will be busy trying to eliminate foods from the diet, things like that, while missing this cause.

    Orgasms are better avoided for optimal health: True or False?

    Aside from the above, False. There is a common myth for men of health benefits of “semen retention”, but it is not based in science, just tradition. You can read a little about it here:

    The short version is: do it if you want; don’t if you don’t; the body will compensate either way so it won’t make a meaningful difference to anything for most people, healthwise.

    Small counterpoint: while withholding orgasm (and ejaculation) is not harmful to health, what does physiologically need draining sometimes is prostate fluid. But that can also be achieved mechanically through prostate milking, or left to fend for itself (as it will in nocturnal emissions, popularly called wet dreams). However, if you have problems with an enlarged prostate, it may not be a bad idea to take matters into your own hands, so to speak. As ever, do check with your doctor if you have (or think you may have) a condition that might affect this.

    One final word…

    We’re done with mythbusting for today, but we wanted to share this study that we came across (so to speak) while researching, as it’s very interesting:

    Clitorally Stimulated Orgasms Are Associated With Better Control of Sexual Desire, and Not Associated With Depression or Anxiety, Compared With Vaginally Stimulated Orgasms

    On which note: if you haven’t already, consider getting a “magic wand” style vibe; you can thank us later (this writer’s opinion: everyone should have one!).

    Top tip: do get the kind that plugs into the wall, not rechargeable. The plug-into-the-wall kind are more powerful, and last much longer (both “in the moment”, and in terms of how long the device itself lasts).

    Enjoy!

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  • How To Recover Quickly From A Stomach Bug

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    How To Recover Quickly From A Stomach Bug

    Is it norovirus, or did you just eat something questionable? We’re not doctors, let alone your doctors, and certainly will not try to diagnose from afar. And as ever, if unsure and/or symptoms don’t go away or do get worse, seek professional medical advice.

    That out of the way, we can give some very good general-purpose tips for this one…

    Help your immune system to help you

    So far as you can, you want a happy healthy immune system. For the most part, we’d recommend the following things:

    Beyond Supplements: The Real Immune-Boosters!

    …but you probably don’t want to be exercising with a stomach bug, so perhaps sit that one out. Exercise is the preventative; what you need right now is rest.

    Hydrate—but watch out

    Hydration is critical for recovery especially if you have diarrhea, but drinking too much water too quickly will just make things worse. Great options for getting good hydration more slowly are:

    • Peppermint tea
      • (peppermint also has digestion-settling properties)
    • Ginger tea
    • Broths
      • These will also help replenish your sodium and other nutrients, gently. Chicken soup for your stomach, and all that. A great plant-based option is sweetcorn soup.
      • By broths, we mean clear(ish) water-based soups. This is definitely not the time for creamier soups.

    ❝Milk and dairy products should be avoided for 24 to 48 hours as they can make diarrhea worse.

    Initial dietary choices when refeeding should begin with soups and broth.❞

    Source: American College of Gastroenterology

    Other things to avoid

    Caffeine stimulates the digestion in a way that can make things worse.

    Fat is more difficult to digest, and should also be avoided until feeling better.

    To medicate or not to medicate?

    Loperamide (also known by the brand name Imodium) is generally safe when used as directed.

    Click here to see its uses, dosage, side effects, and contraindications

    Antibiotics may be necessary for certain microbial infections, but should not be anyone’s first-choice treatment unless advised otherwise by your doctor/pharmacist.

    Note that if your stomach bug is not something that requires antibiotics, then taking antibiotics can actually make it worse as the antibiotics wipe out your gut bacteria that were busy helping fight whatever’s going wrong in there:

    A gentler helper

    If you want to give your “good bacteria” a hand while giving pathogens a harder time of it, then a much safer home remedy is a little (seriously, do not over do it; we are talking 1–2 tablespoons, or around 20ml) apple cider vinegar, taken diluted in a glass of water.

    ❝Several studies indicate apple cider vinegar (ACV)’s usefulness in lowering postprandial glycemic response, specifically by slowing of gastric motility❞

    (Slowing gastric motility is usually exactly what you want in the case of a stomach bug, and apple cider vinegar)

    Source: Effectiveness of Nutritional Ingredients on Upper Gastrointestinal Conditions and Symptoms: A Narrative Review

    See also:

    Take care!

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  • Nasal Hair; How Far To Go?

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    t’s Q&A Day at 10almonds!

    Have a question or a request? You can always hit “reply” to any of our emails, or use the feedback widget at the bottom!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small

    ❝As a man in his sixties I find I need to trim my nasal hair quite frequently, otherwise it sticks out in an unsightly manner. But I’m never sure how severely I should cut the hairs back, or even how best to do it. Please advise.❞

    As you might know, those hairs are really important for our health, so let’s start by mentioning that yes, trimming is the way, not plucking!

    In an ideal world, we’d not trim them further back than the entrance to our nostrils, but given the constant nature of hair-growing, that could become a Sisyphean task.

    A good compromise, if you’re not up for trimming when you get up and having visible hairs by evening, is to put the scissors away (if you haven’t already) and use a nasal hair trimmer; these are good at a) trimming nasal hairs b) abstaining from trimming them too far back.

    By all means shop around, but here’s an example product on Amazon, for your convenience!

    Enjoy!

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  • Capsaicin For Weight Loss And Against Inflammation

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Capsaicin’s Hot Benefits

    Capsaicin, the compound in hot peppers that makes them spicy, is a chemical irritant and a neurotoxin. However, humans being humans, we decided to eat them for fun.

    In contrast to many other ways in which humans recreationally enjoy things that are objectively poisonous, consuming capsaicin (in moderation) is considered to have health benefits, such as aiding weight loss (by boosting metabolism) and reducing inflammation.

    Let’s see what the science says…

    First: is it safe?

    Capsaicin is classified as “Generally Recognized As Safe”. That said, the same mechanism that causes them to boost metabolism, does increase blood pressure:

    Mechanisms underlying the hypertensive response induced by capsaicin

    If you are in good cardiovascular health, this increase should be slight and not pose any threat, unless for example you enter a chili-eating contest when not acclimated to such:

    Capsaicin and arterial hypertensive crisis

    As ever, if unsure, do check with your doctor first, especially if you are taking any blood pressure medications, or otherwise have known blood pressure issues.

    Does it really boost metabolism?

    It certainly does; it works by increasing oxygen consumption and raising body temperature, both of which mean more calories will be burned for the same amount of work:

    Dietary capsaicin and its anti-obesity potency: from mechanism to clinical implications

    This means, of course, that chili peppers enjoy the status of being functionally a “negative calorie” food, and a top-tier one at that:

    Chili pepper as a body weight-loss food

    Here’s a good quality study that showed a statistically significant* fat loss improvement over placebo:

    Capsaicinoids supplementation decreases percent body fat and fat mass: adjustment using covariates in a post hoc analysis

    *To put it in numbers, the benefit was:

    • 5.91 percentage points lower body fat percentage than placebo
    • 6.68 percentage points greater change in body fat mass than placebo

    See also: Difference between percentages and percentage points

    For those who prefer big reviews than single studies, we’ve got you covered:

    The Effects of Capsaicin and Capsiate on Energy Balance: Critical Review and Meta-analyses of Studies in Humans

    Does it really reduce inflammation?

    Counterintuitive as it may seem, yes. By means of reducing oxidative stress. Given that things that reduce oxidative stress tend to reduce inflammation, and in turn tend to reduce assorted disease risks (from diabetes to cancer to Alzheimer’s), this probably has more knock-on benefits too, but we don’t have room to explore all of those today.

    Fresh peppers are best for this, but dried peppers (such as when purchased as a ground spice in the supermarket, or when purchased as a capsule-based supplement) still have a very respectable anti-inflammatory effect:

    How much should we take?

    It’s recommended to start at a low dose and gradually increase it, but 2–6mg of capsaicin per day is the standard range used in studies.

    If you’re getting this from peppers, then for example cayenne pepper (a good source of capsaicin) contains around 2.5mg of capsaicin per 1 gram of cayenne.

    In the case of capsules, if for example you don’t like eating hot pepper, this will usually mean taking 2–6 capsules per day, depending on dosage.

    Make sure to take it with plenty of water!

    Where can we get it?

    Fresh peppers or ground spice from your local grocery store is fine. Your local health food store probably sells the supplements, too.

    If you’d like to buy it online, here is an example product on Amazon.

    Note: options on Amazon were more limited than usual, so this product is not vegan, and probably not halal or kosher, as the capsule contains an unspecified gelatin.

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  • How to Prevent Dementia – by Dr. Richard Restak

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    We’ve written about this topic here, we know. But there’s a lot more we can do to be on guard against, and pre-emptively strengthen ourselves against, dementia.

    The author, a neurologist, takes us on a detailed exploration of dementia in general, with a strong focus on Alzheimer’s in particular, as that accounts for more than half of all dementia cases.

    But what if you can’t avoid it? It could be that with the wrong genes and some other factor(s) outside of your control, it will get you if something else doesn’t get you first.

    Rather than scaremongering, Dr. Restak tackles this head-on too, and discusses how symptoms can be managed, to make the illness less anxiety-inducing, and look to maintain quality of life as much as possible.

    The style of the book is… it reads a lot like an essay compilation. Good essays, then organized and arranged in a sensible order for reading, but distinct self-contained pieces. There are ten or eleven chapters (depending on how we count them), each divided into few or many sections. All this makes for:

    • A very “read a bit now and a bit later and a bit the next day” book, if you like
    • A feeling of a very quick pace, if you prefer to sit down and read it in one go

    Either way, it’s a very informative read.

    Bottom line: if you’d like to better understand the many-headed beast that is dementia, this book gives a far more comprehensive overview than we could here, and also explains the prophylactic interventions available.

    Click here to check out How To Prevent Dementia, because prevention is a lot more fun than wishing for a cure!

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  • I can’t afford olive oil. What else can I use?

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    If you buy your olive oil in bulk, you’ve likely been in for a shock in recent weeks. Major supermarkets have been selling olive oil for up to A$65 for a four-litre tin, and up to $26 for a 750 millilitre bottle.

    We’ve been hearing about the health benefits of olive oil for years. And many of us are adding it to salads, or baking and frying with it.

    But during a cost-of-living crisis, these high prices can put olive oil out of reach.

    Let’s take a look at why olive oil is in demand, why it’s so expensive right now, and what to do until prices come down.

    Joyisjoyful/Shutterstock

    Remind me, why is olive oil so good for you?

    Including olive oil in your diet can reduce your risk of developing type 2 diabetes and improve heart health through more favourable blood pressure, inflammation and cholesterol levels.

    This is largely because olive oil is high in monounsaturated fatty acids and polyphenols (antioxidants).

    Some researchers have suggested you can get these benefits from consuming up to 20 grams a day. That’s equivalent to about five teaspoons of olive oil.

    Why is olive oil so expensive right now?

    A European heatwave and drought have limited Spanish and Italian producers’ ability to supply olive oil to international markets, including Australia.

    This has been coupled with an unusually cold and short growing season for Australian olive oil suppliers.

    The lower-than-usual production and supply of olive oil, together with heightened demand from shoppers, means prices have gone up.

    Green olives on tree
    We’ve seen unfavourable growing conditions in Europe and Australia. KaMay/Shutterstock

    How can I make my olive oil go further?

    Many households buy olive oil in large quantities because it is cheaper per litre. So, if you have some still in stock, you can make it go further by:

    • storing it correctly – make sure the lid is on tightly and it’s kept in a cool, dark place, such as a pantry or cabinet. If stored this way, olive oil can typically last 12–18 months
    • using a spray – sprays distribute oil more evenly than pourers, using less olive oil overall. You could buy a spray bottle to fill from a large tin, as needed
    • straining or freezing it – if you have leftover olive oil after frying, strain it and reuse it for other fried dishes. You could also freeze this used oil in an airtight container, then thaw and fry with it later, without affecting the oil’s taste and other characteristics. But for dressings, only use fresh oil.

    I’ve run out of olive oil. What else can I use?

    Here are some healthy and cheaper alternatives to olive oil:

    • canola oil is a good alternative for frying. It’s relatively low in saturated fat so is generally considered healthy. Like olive oil, it is high in healthy monounsaturated fats. Cost? Up to $6 for a 750mL bottle (home brand is about half the price)
    • sunflower oil is a great alternative to use on salads or for frying. It has a mild flavour that does not overwhelm other ingredients. Some studies suggest using sunflower oil may help reduce your risk of heart disease by lowering LDL (bad) cholesterol and raising HDL (good) cholesterol. Cost? Up to $6.50 for a 750mL bottle (again, home brand is about half the price)
    • sesame oil has a nutty flavour. It’s good for Asian dressings, and frying. Light sesame oil is typically used as a neutral cooking oil, while the toasted type is used to flavour sauces. Sesame oil is high in antioxidants and has some anti-inflammatory properties. Sesame oil is generally sold in smaller bottles than canola or sunflower oil. Cost? Up to $5 for a 150mL bottle.
    Rows of vegetable oil bottles
    There are plenty of alternative oils you can use in salads or for frying. narai chal/Shutterstock

    How can I use less oil, generally?

    Using less oil in your cooking could keep your meals healthy. Here are some alternatives and cooking techniques:

    • use alternatives for baking – unless you are making an olive oil cake, if your recipe calls for a large quantity of oil, try using an alternative such as apple sauce, Greek yoghurt or mashed banana
    • use non-stick cookware – using high-quality, non-stick pots and pans reduces the need for oil when cooking, or means you don’t need oil at all
    • steam instead – steam vegetables, fish and poultry to retain nutrients and moisture without adding oil
    • bake or roast – potatoes, vegetables or chicken can be baked or roasted rather than fried. You can still achieve crispy textures without needing excessive oil
    • grill – the natural fats in meat and vegetables can help keep ingredients moist, without using oil
    • use stock – instead of sautéing vegetables in oil, try using vegetable broth or stock to add flavour
    • try vinegar or citrus – use vinegar or citrus juice (such as lemon or lime) to add flavour to salads, marinades and sauces without relying on oil
    • use natural moisture – use the natural moisture in ingredients such as tomatoes, onions and mushrooms to cook dishes without adding extra oil. They release moisture as they cook, helping to prevent sticking.

    Lauren Ball, Professor of Community Health and Wellbeing, The University of Queensland and Emily Burch, Accredited Practising Dietitian and Lecturer, Southern Cross University

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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