3 drugs that went from legal, to illegal, then back again
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Cannabis, cocaine and heroin have interesting life stories and long rap sheets. We might know them today as illicit drugs, but each was once legal.
Then things changed. Racism and politics played a part in how we viewed them. We also learned more about their impact on health. Over time, they were declared illegal.
But decades later, these drugs and their derivatives are being used legally, for medical purposes.
Here’s how we ended up outlawing cannabis, cocaine and heroin, and what happened next.
Cannabis, religion and racism
Cannabis plants originated in central Asia, spread to North Africa, and then to the Americas. People grew cannabis for its hemp fibre, used to make ropes and sacks. But it also had other properties. Like many other ancient medical discoveries, it all started with religion.
Cannabis is mentioned in the Hindu texts known as the Vedas (1700-1100 BCE) as a sacred, feel-good plant. Cannabis or bhang is still used ritually in India today during festivals such as Shivratri and Holi.
From the late 1700s, the British in India started taxing cannabis products. They also noticed a high rate of “Indian hemp insanity” – including what we’d now recognise as psychosis – in the colony. By the late 1800s, a British government investigation found only heavy cannabis use seemed to affect people’s mental health.
In the 1880s, cannabis was used therapeutically in the United States to treat tetanus, migraine and “insane delirium”. But not everyone agreed on (or even knew) the best dose. Local producers simply mixed up what they had into a tincture – soaking cannabis leaves and buds in alcohol to extract essential oils – and hoped for the best.
So how did cannabis go from a slightly useless legal drug to a social menace?
Some of it was from genuine health concerns about what was added to people’s food, drink and medicine.
In 1908 in Australia, New South Wales listed cannabis as an ingredient that could “adulterate” food and drink (along with opium, cocaine and chloroform). To sell the product legally, you had to tell the customers it contained cannabis.
Some of it was international politics. Moves to control cannabis use began in 1912 with the world’s first treaty against drug trafficking. The US and Italy both wanted cannabis included, but this didn’t happen until until 1925.
Some of it was racism. The word marihuana is Spanish for cannabis (later Anglicised to marijuana) and the drug became associated with poor migrants. In 1915, El Paso, Texas, on the Mexican border, was the first US municipality to ban the non-medical cannabis trade.
By the late 1930s, cannabis was firmly entrenched as a public menace and drug laws had been introduced across much of the US, Europe and (less quickly) Australia to prohibit its use. Cannabis was now a “poison” regulated alongside cocaine and opiates.
The 1936 movie Reefer Madness was a high point of cannabis paranoia. Cannabis smoking was also part of other “suspect” new subcultures such as Black jazz, the 1950s Beatnik movement and US service personnel returning from Vietnam.
Today recreational cannabis use is associated with physical and mental harm. In the short term, it impairs your functioning, including your ability to learn, drive and pay attention. In the long term, harms include increasing the risk of psychosis.
But what about cannabis as a medicine? Since the 1980s there has been a change in mood towards experimenting with cannabis as a therapeutic drug. Medicinal cannabis products are those that contain cannabidiol (CBD) or tetrahydrocannabinol (THC). Today in Australia and some other countries, these can be prescribed by certain doctors to treat conditions when other medicines do not work.
Medicinal cannabis has been touted as a treatment for some chronic conditions such as cancer pain and multiple sclerosis. But it’s not clear yet whether it’s effective for the range of chronic diseases it’s prescribed for. However, it does seem to improve the quality of life for people with some serious or terminal illnesses who are using other prescription drugs.
Cocaine, tonics and addiction
Several different species of the coca plant grow across Bolivia, Peru and Colombia. For centuries, local people chewed coca leaves or made them into a mildly stimulant tea. Coca and ayahuasca (a plant-based psychedelic) were also possibly used to sedate people before Inca human sacrifice.
In 1860, German scientist Albert Niemann (1834-1861) isolated the alkaloid we now call “cocaine” from coca leaves. Niemann noticed that applying it to the tongue made it feel numb.
But because effective anaesthetics such as ether and nitrous oxide had already been discovered, cocaine was mostly used instead in tonics and patent medicines.
Perhaps the most famous example was Coca-Cola, which contained cocaine when it was launched in 1886. But cocaine was used earlier, in 1860s Italy, in a drink called Vin Mariani – Pope Leo XIII was a fan.
With cocaine-based products easily available, it quickly became a drug of addiction.
Cocaine remained popular in the entertainment industry. Fictional detective Sherlock Holmes injected it, American actor Tallulah Bankhead swore by it, and novelist Agatha Christie used cocaine to kill off some of her characters.
In 1914, cocaine possession was made illegal in the US. After the hippy era of the 1960s and 1970s, cocaine became the “it” drug of the yuppie 1980s. “Crack” cocaine also destroyed mostly Black American urban communities.
Cocaine use is now associated with physical and mental harms. In the short and long term, it can cause problems with your heart and blood pressure and cause organ damage. At its worst, it can kill you. Right now, illegal cocaine production and use is also surging across the globe.
But cocaine was always legal for medical and surgical use, most commonly in the form of cocaine hydrochloride. As well as acting as a painkiller, it’s a vasoconstrictor – it tightens blood vessels and reduces bleeding. So it’s still used in some types of surgery.
Heroin, coughing and overdoses
Opium has been used for pain relief ever since people worked out how to harvest the sap of the opium poppy. By the 19th century, addictive and potentially lethal opium-based products such as laudanum were widely available across the United Kingdom, Europe and the US. Opium addiction was also a real problem.
Because of this, scientists were looking for safe and effective alternatives for pain relief and to help people cure their addictions.
In 1874, English chemist Charles Romley Alder Wright (1844-1894) created diacetylmorphine (also known as diamorphine). Drug firm Bayer thought it might be useful in cough medicines, gave it the brand name Heroin and put it on the market in 1898. It made chest infections worse.
Although diamorphine was created with good intentions, this opiate was highly addictive. Shortly after it came on the market, it became clear that it was every bit as addictive as other opiates. This coincided with international moves to shut down the trade in non-medical opiates due to their devastating effect on China and other Asian countries.
Like cannabis, heroin quickly developed radical chic. The mafia trafficked into the US and it became popular in the Harlem jazz scene, beatniks embraced it and US servicemen came back from Vietnam addicted to it. Heroin also helped kill US singers Janis Joplin and Jim Morrison.
Today, we know heroin use and addiction contributes to a range of physical and mental health problems, as well as death from overdose.
However, heroin-related harm is now being outpaced by powerful synthetic opioids such as oxycodone, fentanyl, and the nitazene group of drugs. In Australia, there were more deaths and hospital admissions from prescription opiate overdoses than from heroin overdoses.
In a nutshell
Not all medicines have a squeaky-clean history. And not all illicit drugs have always been illegal.
Drugs’ legal status and how they’re used are shaped by factors such as politics, racism and social norms of the day, as well as their impact on health.
Philippa Martyr, Lecturer, Pharmacology, Women’s Health, School of Biomedical Sciences, The University of Western Australia
This article is republished from The Conversation under a Creative Commons license. Read the original article.
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Top 10 Early Warning Signs Of Dementia
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What’s a harmless momentary mind-blank, and what’s a potential warning sign of dementia? Dementia Careblazers, a dementia care organization, has input:
The signs
With the caveat that this is a list of potential warning signs, not a diagnostic tool, the 10 signs are:
- Memory loss: e.g. forgetting important or well-learned information, such as one’s home address
- Challenges in planning or solving problems: e.g. difficulty with tasks such as paying bills (for organizational rather than financial reasons), following recipes, or managing medications
- Difficulty completing familiar tasks: e.g. trouble remembering rules of a familiar game, or directions to a familiar place
- Confusion with place or time: e.g. forgetting where one is, or making mistakes with the date, season, or other time-related details. Note that anyone can be momentarily unsure of today’s date, but if someone thinks it’s 1995, probably something wrong is not quite right. Similarly, being wrong about who is the current national leader is often used as a test, too—assuming countries with enough political stability to not have five different national leaders in the past four years, including one who did not outlast a lettuce *side-eyeing the UK*
- Trouble understanding visual images and spatial relationships: e.g. increased clumsiness, difficulty parking, or bumping into objects
- New problems with speaking or writing: e.g. losing track in conversations, or struggling to find the right words
- Misplacing things: e.g. losing items and being unable to retrace one’s steps to find them
- Decreased or poor judgment: e.g. falling for scams, giving out too much information or money without investigating appropriately first
- Withdrawal from social activities or hobbies: e.g. losing interest in activities one used to enjoy or avoiding social interactions
- Changes in mood and personality: e.g. increased irritability, anxiety, or other noticeable changes in behavior and personality
For more information on each of these, enjoy:
Click Here If The Embedded Video Doesn’t Load Automatically!
Want to learn more?
You might also like to read:
Dementia: Spot The Signs (Because None Of Us Are Immune)
Take care!
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Measles cases are rising—here’s how to protect your family
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The U.S. is currently experiencing a spike in measles cases across several states. Measles a highly contagious and potentially life-threatening disease caused by a virus. The measles-mumps-rubella (MMR) vaccine prevents measles; unvaccinated people put themselves and everyone around them at risk, including babies who are too young to receive the vaccine.
Read on to learn more about measles: what it is, how to stay protected, and what to do if a measles outbreak happens near you.
What are the symptoms of measles?
Measles symptoms typically begin 10 to 14 days after exposure. The disease starts with a fever followed by a cough, runny nose, and red eyes and then produces a rash of tiny red spots on the face and body. Measles can affect anyone, but is most serious for children under 5, immunocompromised people, and pregnant people, who may give birth prematurely or whose babies may have low birth weight as a result of a measles infection.
Measles isn’t just a rash—the disease can cause serious health problems and even death. About one in five unvaccinated people in the U.S. who get measles will be hospitalized and could suffer from pneumonia, dehydration, or brain swelling.
If you get measles, it can also damage your immune system, making you more vulnerable to other diseases.
How do you catch measles?
Measles spreads through the air when an infected person coughs or sneezes. It’s so contagious that unvaccinated people have a 90 percent chance of becoming infected if exposed.
An infected person can spread measles to others before they have symptoms.
Why are measles outbreaks happening now?
The pandemic caused many children to miss out on routine vaccinations, including the MMR vaccine. Delayed vaccination schedules coincided with declining confidence in vaccine safety and growing resistance to vaccine requirements.
Skepticism about the safety and effectiveness of COVID-19 vaccines has resulted in some people questioning or opposing the MMR vaccine and other routine immunizations.
How do I protect myself and my family from measles?
Getting an MMR vaccine is the best way to prevent getting sick with measles or spreading it to others. The CDC recommends that children receive the MMR vaccine at 12 to 15 months and again at 4 to 6 years, before starting kindergarten.
One dose of the MMR vaccine provides 93 percent protection and two doses provide 97 percent protection against all strains of measles. Because some children are too young to be immunized, it’s important that those around them are vaccinated to protect them.
Is the MMR vaccine safe?
The MMR vaccine has been rigorously tested and monitored over 50 years and determined to be safe. Adverse reactions to the vaccine are extremely rare.
Receiving the MMR vaccine is much safer than contracting measles.
What do I do if there’s a measles outbreak in my community?
Anyone who is not fully vaccinated for measles should be immunized with a measles vaccine as soon as possible. Measles vaccines given within 72 hours after exposure may prevent or reduce the severity of disease.
Children as young as 6 months old can receive the MMR vaccine if they are at risk during an outbreak. If your child isn’t fully vaccinated with two doses of the MMR vaccine—or three doses, if your child received the first dose before their first birthday—talk to your pediatrician.
Unvaccinated people who have been exposed to the virus should stay home from work, school, day care, and other activities for 21 days to avoid spreading the disease.
For more information, talk to your health care provider.
This article first appeared on Public Good News and is republished here under a Creative Commons license.
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Science-backed ways to take care of your mental health this winter
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The colder, darker months can take a toll on well-being. Two out of five U.S. adults say their mental health worsens in the winter. Plus, about five percent of U.S. adults experience seasonal affective disorder (SAD), a type of depression induced by seasonal changes that typically begins when the weather gets colder and there’s less daylight.
Fortunately, there are science-backed lifestyle changes that can make this time of year more tolerable. Here’s how to take care of your mental health this winter.
Exercise regularly
When you exercise, your body releases endorphins, or “feel-good” chemicals that can improve your mood. A 2024 review of studies found that exercise—particularly walking, jogging, yoga, and strength training—can reduce symptoms of depression.
Before starting a new exercise routine, talk to your health care provider about the types of exercise that may work best for you.
Get outside
While getting outside during the colder months may feel challenging, time outdoors—especially in nature—has been shown to decrease stress, depression, and anxiety. Plus, sunlight helps your body make vitamin D, which may improve your energy and mood.
You can reap the benefits of nature no matter where you live.
“Cities can be very energetic and exciting but also can contribute to both conscious and unconscious stress from the sensory overload and challenges of maneuvering in those spaces,” said Jodie M. Smith, a Mayo Clinic nurse practitioner, in a 2024 Mayo Clinic article. “If you live in an urban environment, exploring to find even a small natural reprieve can be extremely beneficial.”
Prioritize sleep
Inadequate sleep has been linked to depression and anxiety. Taking steps to improve the quality and duration of your sleep can help you become more resilient against stressors.
You can improve your sleep by going to bed and waking up at the same time every day; avoiding caffeine, alcohol, and large meals before bed; keeping your bedroom cool and dark; and limiting exposure to distressing media in the evening.
Practice gratitude
Research suggests that people who practice gratitude are less likely to experience depression. It can also help you make lifestyle changes that improve your well-being overall.
“Practicing gratitude may also make someone a bit more motivated to take care of their health,” said Tyler VanderWeele, co-director of the Initiative on Health, Spirituality, and Religion at the Harvard T.H. Chan School of Public Health, in a 2024 Harvard Health Publishing article. “Maybe they’re more likely to show up for medical appointments or exercise. It may also help with relationships and social support, which we know contribute to health.”
Add more gratitude to your life by sharing what you’re grateful for with others or keeping a gratitude journal.
Spend quality time with loved ones
“Social isolation and loneliness have a serious impact on physical and mental health, quality of life, and longevity,” according to the World Health Organization, with effects comparable to other risk factors like smoking.
Research shows that people who have close confidants are more satisfied with their lives and less likely to experience depression. Even after holiday gatherings have ended, schedule time with friends and family to stay positive and feel supported.
Limit cell phone use
Social media use and “doomscrolling” inflammatory news headlines are both associated with anxiety and depression across age groups, especially in teens.
“Excessive social media use is associated with behaviors, such as poor sleep, increased social comparisons, impact on learning, and exposure to cyberbullying and negative content, that could contribute to the worsening of depressive symptoms,” Dr. Carol Vidal, an assistant professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine, said in a Hopkins Medicine article.
Minimize the time you and your family members spend on your phones by pausing notifications, keeping your phone out of reach when you’re preparing for sleep, using a “grayscale” setting to make scrolling less enticing, and finding phone-free hobbies to enjoy.
Light therapy
Light therapy is one treatment for people who have been diagnosed with SAD. It involves sitting in front of a bright light box for 30 to 45 minutes per day to increase light exposure.
This treatment may not be right for people who take certain medications or have eye diseases. Talk to your health care provider about whether light therapy is right for you and what type of light box you should use.
Seek professional support
If your mental health over the winter interferes with your daily functioning, seek help from a therapist, support group, or mental health hotline. Find resources here.
This article first appeared on Public Good News and is republished here under a Creative Commons license.
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Dreams: Relevance, Meanings, Interpretations
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It’s Q&A Day at 10almonds!
Have a question or a request? We love to hear from you!
In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!
As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!
So, no question/request too big or small
❝I have a question or a suggestion for coverage in your “Psychology Sunday”. Dreams: their relevance, meanings ( if any) interpretations? I just wondered what the modern psychological opinions are about dreams in general.❞
We’ll indeed do that one of these Psychology Sundays! Thanks for suggesting it.
What we can say in advance is that there’s certainly not a single unified scientific consensus yet, but there are two or three prevailing views definitely worth covering, e.g. randomly generated, a by-product of reorganizing information in the brain, or expressions of subconscious thoughts/feelings.
There are also differences between a top-down/bottom-up approach to understanding dreaming, and efforts to tie those two together.
Watch this space!
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Exercising With Less Soreness!
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An Ancient Sports Drink & Healing Potion, Now With Modern Science?
Ginseng has many health benefits, we talked about 8 of them in this previous edition of 10almonds:
…but we’ve somehow never yet done a Monday’s Research Review for it! We must do one, one of these days. For now though, it’s Saturday’s Life Hacks, and we’re here with…
Speeding up recovery after muscle damage
We talked about this topic before too:
Overdone It? How To Speed Up Recovery After Exercise
…which gives very good advice (including some supplements that help), but was published before the latest science that we’re going to talk about today:
A team of researchers all so very recently found that ginseng also reduces muscular fatigue and, importantly, hastens recovery of muscle damage caused by exercise.
And that’s not all…
❝It should also be noted that, by reducing fatigue, taking ginseng on a regular basis may also help reduce the risk of injury, particularly in the case of muscles or ligaments, which can in turn improve athletic performance.❞
This means that it can be taken regularly and prophylactically, as they found:
❝taking ginseng systematically for a long time can mitigate the response of the biological markers, mainly creatine kinase (CK) and interleukin 6 (IL-6), responsible for exercise-induced muscle damage and inflammation.❞
You may be thinking “isn’t creatine good?” and yes, yes it is:
Creatine: Very Different For Young & Old People
…however, creatine kinase is not creatine. Creatine kinase (CK) is an enzyme that affects the creatine (to put it in few words, without getting into the fascinating biochemistry of this). Now, it’s necessary for us to have some CK (or else we wouldn’t be able to do what we need to with the creatine), but elevated levels often indicate some sort of problem going on:
Approach to asymptomatic creatine kinase elevation
…so ginseng keeping those things balanced is a good thing.
The study
We’ve talked a lot about the findings and what they mean, but if you’d like to read the paper for yourself, you can read it here:
Effect of Ginseng Intake on Muscle Damage Induced by Exercise in Healthy Adults
Where to get ginseng
If you’d like to take ginseng as a supplement, then there are many ways to do so, with the most common being capsules or ginseng tea, which has an interesting and distinctive taste, and is very refreshing. Here are examples on Amazon, for your convenience:
Enjoy!
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Your Health Audit, From Head To Toe
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Health Audit Time
Here at 10almonds, we often cover quite specific things, ranging from “the effect of sodium on organs other than your heart” to “make this one small change to save your knees while driving”.
But, we’re each a whole person, and we need to take care of the whole organism that makes up the wonderful being that we each are. If we let one part of it drop in health too much, the others will soon follow suit because of the knock-on effects.
So, let’s do a quick self-check-up, and see what can be done for each! How’s your…
Mental Health
We’re doing this audit head-to-to, so let’s start it here, because mental health is also just health, and it’s difficult to tackle the others without having this one at least under control!
Are you experiencing chronic stress? Anxiety? Depression? Joy?
If you answered “no” to “joy” but also “no” to “depression”, you might want to rethink your answer to “depression”, by the way. Life should be a joyous thing!
Some resources to address your mental health:
Brain Health
Your brain is a big, powerful organ. It uses more of your daily energy (in the physiological sense of the word, we’re talking calories and mitochondria and ATP) than any other organ, by far.
And when it comes to organ failure, if your brain fails, then having the best joints in the world won’t help you, for example.
Some resources to address your brain health:
- Brain Food? The Eyes Have It
- How To Reduce Your Alzheimer’s Risk
- The 6 Dimensions Of Sleep (And Why They Matter)
Heart Health
Everything depends on your heart, head to toe. Tirelessly pumping blood with oxygen, nutrients, and agents of your immune system all around your body, all day every day for your entire life.
What’s your resting heart rate like? How about your blood pressure? And while we’re on the topic of blood… how’s your blood sugar health?
These are all important things to a) know about and b) keep on top of!
Some resources to address your heart health:
- 1-Minute Heart Health Check-Up Tips
- A Five-Point Plan For Heart Health
- High Blood Pressure? Try These!
Gut Health
By cell count, we’re about 10% human and 90% bacteria. By gene count, also. Pretty important, therefore, that we look after our trillions of tiny friends that keep our organism working.
Most people in N. America, for example, get vastly under the recommended daily amount of fiber, and that’s just the most basic courtesy we could do for these bugs that keep us alive (they need that fiber to live, and their process of consuming it is beneficial to us in a stack of ways).
Some resources to address your gut health:
- Making Friends With Your Gut (You Can Thank Us Later)
- The Surprising Link Between Gut Health And Serotonin
- The Vagus Nerve: The Brain-Gut Highway!
Hormonal Health
Hormones are weird and wonderful and affect so much more than the obvious sex-related functions (but yes, those too). A lot of people don’t realize it, but having our hormones in good order or not can make the difference between abject misery and a happy, fulfilling life.
Some resources to address your hormonal health:
- What Does “Balance Your Hormones” Even Mean?
- Healthy Hormones And How To Hack Them
- Too Much Or Too Little Testosterone?
Bone/Joint Health
Fear nothing! For you are a ghost operating a skeleton clad in flesh. But also, you know, look after that skeleton; you only get one! Being animals, we’re all about movement, and being humans, we’ve ended up with some lifestyle situations that aren’t great for that mobility. We sit too much; we walk too little; we cramp ourselves into weird positions (driving, anyone?), and we forget the range of motion we’re supposed to have. But let’s remember…
Some resources to address your bone/joint health:
- Collagen’s benefits are more than skin deep
- Cool As A Cucumber (Move Over, Glucosamine + Chondroitin)
- 5 Best Bodyweight Exercises For Incredible Mobility
Lastly…
While it’s good to do a little self-audit like this every now and again, it’s even better to get a professional check-up!
As engineers say: if you don’t schedule time for maintenance, your equipment will schedule it for you.
Don’t Forget…
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