The Epigenetics Revolution – by Dr. Nessa Carey

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If you enjoyed the book “Inheritance” that we reviewed a couple of days ago, you might love this as a “next read” book. But you can also just dive straight in here, if you like!

This one, as the title suggests, focuses entirely on epigenetics—how our life events can shape our genetic expression, and that of our descendants. Or to look at it in the other direction, how our genetic expression can be shaped by the life experiences of, for example, our grandparents.

The style of this book is very much pop-science, but contains a lot of information from hard science throughout. We learn not just about longitudinal population studies as one might expect, but also about the intricacies of DNA methylation and histone modifications, for example.

Depending on your outlook, you may find some of this very bleak (“great, I am shackled by what my grandparents did”) or very optimism-inducing (“oh wow, I’m not nearly so constrained by genetics as I thought; this stuff is so malleable!”). This is also the same author who wrote “Hacking The Code of Life“, by the way, but we’ll review that another day.

Bottom line: this book is the best one-shot primer on epigenetics that this reviewer has read (you may be wondering how many that is, and the answer is… about seven or so? I’m not good at counting).

Click here to check out The Epigenetics Revolution, and learn how dynamic you really are!

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  • See what other 10almonds subscribers are asking!

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    It’s Q&A Day at 10almonds!

    Q: I would be interested in learning more about collagen and especially collagen supplements/powders and of course if needed, what is the best collagen product to take. What is collagen? Why do we need to supplement the collagen in our body? Thank you PS love the information I am receiving in the news letters. Keep it up

    We’re glad you’re enjoying them! Your request prompted us to do our recent Research Review Monday main feature on collagen supplementation—we hope it helped, and if you’ve any more specific (or other) question, go ahead and let us know! We love questions and requests

    Q: Great article about the health risks of salt to organs other than the heart! Is pink Himalayan sea salt, the pink kind, healthier?

    Thank you! And, no, sorry. Any salt that is sodium chloride has the exact same effect because it’s chemically the same substance, even if impurities (however pretty) make it look different.

    If you want a lower-sodium salt, we recommend the kind that says “low sodium” or “reduced sodium” or similar. Check the ingredients, it’ll probably be sodium chloride cut with potassium chloride. Potassium chloride is not only not a source of sodium, but also, it’s a source of potassium, which (unlike sodium) most of us could stand to get a little more of.

    For your convenience: here’s an example on Amazon!

    Bonus: you can get a reduced sodium version of pink Himalayan salt too!

    Q: Can you let us know about more studies that have been done on statins? Are they really worth taking?

    That is a great question! We imagine it might have been our recent book recommendation that prompted it? It’s quite a broad question though, so we’ll do that as a main feature in the near future!

    Q: Is MSG healthier than salt in terms of sodium content or is it the same or worse?

    Great question, and for that matter, MSG itself is a great topic for another day. But your actual question, we can readily answer here and now:

    • Firstly, by “salt” we’re assuming from context that you mean sodium chloride.
    • Both salt and MSG do contain sodium. However…
    • MSG contains only about a third of the sodium that salt does, gram-for-gram.
    • It’s still wise to be mindful of it, though. Same with sodium in other ingredients!
    • Baking soda contains about twice as much sodium, gram for gram, as MSG.

    Wondering why this happens?

    Salt (sodium chloride, NaCl) is equal parts sodium and chlorine, by atom count, but sodium’s atomic mass is lower than chlorine’s, so 100g of salt contains only 39.34g of sodium.

    Baking soda (sodium bicarbonate, NaHCO₃) is one part sodium for one part hydrogen, one part carbon, and three parts oxygen. Taking each of their diverse atomic masses into account, we see that 100g of baking soda contains 27.4g sodium.

    MSG (monosodium glutamate, C₅H₈NO₄Na) is only one part sodium for 5 parts carbon, 8 parts hydrogen, 1 part nitrogen, and 4 parts oxygen… And all those other atoms put together weigh a lot (comparatively), so 100g of MSG contains only 12.28g sodium.

    Q: Thanks for the info about dairy. As a vegan, I look forward to a future comment about milk alternatives

    Thanks for bringing it up! What we research and write about is heavily driven by subscriber feedback, so notes like this really help us know there’s an audience for a given topic!

    We’ll do a main feature on it, to do it justice. Watch out for Research Review Monday!

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  • Jamaican Coconut Rice

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    This is a great dish that can be enjoyed hot or cold, as a main or as a side. It has carbs, proteins, healthy fats, fiber, as well as an array of healthy phytochemicals. Not to mention, a great taste!

    You will need

    • 1 cup wholegrain basmati rice (it may also be called “brown basmati rice“; this is the same) (traditional recipe calls for pudding rice, but we’re going with the healthier option here)
    • 2 cans (each 12 z / 400g) coconut milk
    • 2 cups (or 2 cans, of which the drained weight is comparable to a cup each) cooked black beans. If you cook them yourself, this is better, as you will be able to cook them more al dente than you can get from a can, and this firmness is desirable. But canned is fine if that’s what’s available.
    • 1 large red onion, finely chopped
    • ½ cup low-sodium vegetable stock (ideally you made this yourself from vegetable offcuts you saved in the freezer for this purpose, but failing that, low-sodium stock cubes can be bought at any large supermarket)
    • 2 serrano chilis, finely chopped
    • 1 Scotch bonnet chili, without doing anything to it
    • 1 tbsp black pepper, coarse ground
    • 1 tbsp chia seeds
    • 1 tbsp coconut oil
    • Garnish: parsley, chopped

    Note: we have erred on the side of low-heat when it comes to the chilis. If you know that you and (if applicable) everyone else eating would enjoy more heat, add more heat. If not, let extra heat be added at the table via your hot sauce of choice. Sounds heretical, but it ensures everyone gets the right amount! It’s easy to add heat than to take it out, after all.

    However: if you do end up with too much heat in this or any other dish, adding acid will usually help to neutralize that. In the case of this dish, we’d recommend lime juice as a complementary flavor.

    Method

    (we suggest you read everything at least once before doing anything)

    1) In a big sauté pan, add the coconut oil, melt it if not already melted, and add the chopped onion and the chopped chilis, at a temperature sufficient to sizzle. Keep them all moving. Once the coconut oil is absorbed into the onion (this will happen before the onion is fully cooked), add the vegetable stock, followed by the coconut milk; mix it all gently to create a smooth consistency.

    2) Add the rice, chia seeds, and black pepper; mix it all gently but thoroughly; turn the temperature to a simmer, and add the Scotch bonnet chili, without cutting it at all.

    3) Cover and keep on low for about 20–30 minutes until the rice is looking done. Check on it periodically to make sure it’s not running out of liquid, but resist the urge to stir it; it shouldn’t be burning but paradoxically, once you start stirring you can’t stop or it will definitely burn.

    4) Take out the Scotch bonnet chili, and discard*. Add the black beans.

    *its job was to add flavor without adding the high-level heat of that particular chili. If you’re a regular heat-fiend, feel free to experiment with using sliced Scotch bonnet chilis instead of serrano chilis; just be aware that there’s a big difference in heat. Only do this if you really like heat. Using it the way we described in the main recipe is what’s traditional in the Caribbean, by the way.

    5) Now you can (and in fact must) stir, to mix in the black beans and bring them back to temperature within the dish. Be aware that once you start stirring, you need to keep stirring until you’re ready to take it off the heat.

    6) Serve, adding the parsley garnish.

    (this example went light on the beans; our recipe includes more for a heartier dish)

    Enjoy!

    Want to learn more?

    For those interested in some of the science of what we have going on today:

    Take care!

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  • What is hyaluronic acid – and is it OK for kids and teens to use this common skincare ingredient?

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    Earlier this month, Kmart pulled a “hyaluronic acid cleansing balm” from its shelves, after a teen who used the skincare product was hospitalised, reporting eye pain and blurred vision. It’s unclear what ingredient caused this reaction.

    In a statement, Kmart said it was removing the product while conducting an investigation. The retailer also said:

    We want to assure our customers that our cosmetics are designed to ensure that they comply with both Australian and European requirements on ingredients.

    Hyaluronic acid – despite the name – is a gentle ingredient commonly used in skincare products.

    But what does hyaluronic acid do to your skin as a skincare ingredient? And is it safe for tweens and teens?

    Sabinayro/Shutterstock

    What is hyaluronic acid?

    Hyaluronic acid is a glycosaminoglycan – a sugar-based molecule found naturally in the skin, eyes, joint fluid and connective tissue.

    It plays a key role in hydrating the skin and tissues, lubricating our joints and supporting tissue repair.

    Beyond cosmetics, hyaluronic acid is used in drug delivery, regenerative medicine, wound repair, and to treat conditions such as atherosclerosis (where the arterial walls harden and narrow) and osteoarthritis (a degenerative joint disease).

    It is also a key ingredient in many eye drops and contact lens care solutions.

    How is it used in skincare?

    While the word “acid” might suggest it is harsh and potentially damaging to the skin, hyaluronic acid is not used in its acidic form in skincare products. It is usually used in its salt form, sodium hyaluronate.

    In skincare, active acids such as salicylic acid usually lower the skin’s pH and exfoliate it by breaking the bonds between dead skin cells.

    Hyaluronic acid, in contrast, is used to hydrate the skin. It is a humectant, an ingredient that attracts and retains water molecules.

    Hyaluronic acid has three qualities that make it suitable for skincare: it’s soluble (can be dissolved in water), biocompatible (meaning it’s not harmful to the body), and biodegradable (naturally breaks down into non-toxic, simpler substances).

    It is usually safe and well-tolerated, meaning it has very few side effects.

    In skincare products, hyaluronic is used in different forms. Smaller hyaluronic molecules can penetrate deeper into the skin and hydrate the lower levels. In products this is often advertised as “anti-ageing”, because it stimulates the production of collagen (a structural protein in the skin), and helps to improve elasticity and reduce the appearance of fine lines.

    Larger hyaluronic acid molecules remain on the skin’s surface and have an immediate hydrating effect, preventing water evaporation from the skin.

    Teen girl washes her face at the bathroom sink.
    Hyaluronic acid helps the skin attract and retain water molecules for hydration. Art_Photo/Shutterstock

    Any risks?

    Hyaluronic acid is generally a safe ingredient, even for sensitive skin. But products advertised as “hyaluronic acid skincare” may contain other ingredients which can cause irritation.

    In particular, fragrances, preservatives and surfactants (ingredients that produce foam and help wash away oil and dirt) may be safe for skin but burn or otherwise irritate the eyes.

    This is because the cornea and conjuctiva (the thin membrane covering the eye) are much more sensitive than the skin.

    How are skincare ingredients regulated?

    Unlike medicines and products used for therapeutic reasons, which are regulated by the Therapeutic Goods Administration (TGA), general cosmetic products do not require pre-market safety testing or approval.

    Instead, companies need to register their business with the Australian Industrial Chemicals Introduction Scheme and verify that their ingredients are not banned or restricted in Australia.

    This creates a potential gap where defective products remain on the market, only to be recalled after adverse reactions occur.

    Are these products appropriate for children?

    Most scientific research on active ingredients – including hyaluronic acid – has been evaluated in older populations. This leaves a gap in understanding how they affect teen and preteen skin.

    Many products are designed for ageing and/or specific skin types, and are largely unnecessary for children and younger people.

    In some cases, they can potentially be harmful to their skin. For example, unless prescribed by a dermatologist, it’s advisable for young people to avoid retinoid products (containing retinol or retinal) as they can cause redness, peeling and drying.

    Similarly, products with alpha hydroxy acids can cause irritation, itching, redness and may worsen acne in young skin.

    So, what should younger people look for?

    Preteens and teens should avoid products containing active ingredients such as retinol, vitamin C, alpha- and beta- hydroxy acids, and peptides, as well as those labelled with terms such as anti-ageing, wrinkle-reducing, brightening, or firming.

    To keep skin clean and protected, teenagers can use a good cleanser, a simple moisturiser and a broad spectrum SPF 30 or 50 sunscreen.

    It’s best to opt for gentle, fragrance-free cleansers and moisturisers suitable for all skin types. Consulting with a pharmacist can provide personalised recommendations based on individual skin needs.

    Zoe Porter, Lecturer, Pharmacy and Pharmaceutical Science, Monash University and Laurence Orlando, Senior Lecturer, Product Formulation and Development, Analytical Methods, Monash University

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Hold The Banana!

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    Bananas are a healthy fruit for most people (there is such a thing as a banana allergy, so we can’t extend it to all people, but certainly most people).

    Full of fiber, carbs for energy, vitamins and minerals, and a stack of nutritious phytochemicals.

    One thing we will quickly say as a small counterpoint, which isn’t the main point of today’s article but is worth mentioning: the claim of bananas being “a good source of potassium” is true but greatly overstated; they’re not even in the top 10 of fruits for potassium; just, it was mentioned in a popular TV show, referenced in another popular TV show, and then the English-speaking world never let it go.

    But that’s just a minor “not quite as good as people make it out to be” thing, rather than an actual negative.

    So, what’s the problem with bananas?

    It’s about polyphenol oxidase (PPO)

    Researchers (Dr. Jodi Ensunsa et al.) found that adding bananas to berry smoothies drastically reduced flavanol absorption, with blood levels dropping by about 84% compared with a flavanol capsule or a low-PPO berry smoothie.

    Quick recap on what flavanols are: flavanols are a kind of polyphenolic plant compounds linked to cardiovascular and cognitive health, that are found in foods like blueberries, blackberries, grapes, apples, pears, tea, and cocoa.

    See for example: Are You Getting The Right Kinds Of Flavonoids? ← flavanols are a kind of flavonoid

    Why bananas had this effect: bananas contain high amounts of polyphenol oxidase (PPO), which (as you might have guessed) mediates the oxidation of polyphenols; it’s the enzyme responsible for the browning of cut fruit, and the researchers believe PPO breaks down flavanols before your body can absorb them.

    What the study tested: healthy participants consumed:

    • a banana-based smoothie with high PPO activity
    • a mixed berry smoothie with low PPO activity
    • a flavanol capsule control

    What they saw in the results: the berry smoothie produced flavanol absorption similar to the capsule control, while the banana smoothie produced much lower levels of flavanol metabolites in blood samples.

    Also! A surprising follow-up finding: even when flavanols and banana were kept separate until consumption, absorption was still reduced, suggesting that PPO continues degrading flavanols in the stomach after ingestion.

    You can read the paper in full, here: Impact of polyphenol oxidase on the bioavailability of flavan-3-ols in fruit smoothies: a controlled, single blinded, cross-over study

    Quick note before we move on: no, the study doesn’t mean bananas are unhealthy; bananas still provide many wonderful nutrients; it’s just that they don’t pair well with flavanol-rich foods if maximizing flavanol intake is your goal 🙂

    Want to learn more?

    On a similar topic (it has many important bits of information like the one we discussed today), you might like to check out:

    Make Your Vegetables Work Better Nutritionally

    As for why you might want to favor getting it from food if you can, then while the title says “vitamins”, this book discusses an assortment of vitamins, minerals, and other nutrients; the “other nutrients” category including amino acids (branched chain and essential), prebiotics and probiotics, and triglycerides of various kinds:

    Eat Your Vitamins – by Mascha Davis, RDN ← see our review, here

    Take care!

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  • Dating apps could have negative effects on body image and mental health, our research shows

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    Around 350 million people globally use dating apps, and they amass an estimated annual revenue of more than US$5 billion. In Australia, 49% of adults report using at least one online dating app or website, with a further 27% having done so in the past.

    But while dating apps have helped many people find romantic partners, they’re not all good news.

    In a recent review, my colleagues and I found using dating apps may be linked to poorer body image, mental health and wellbeing.

    Dikushin Dmitry/Shutterstock

    We collated the evidence

    Our study was a systematic review, where we collated the results of 45 studies that looked at dating app use and how this was linked to body image, mental health or wellbeing.

    Body image refers to the perceptions or feelings a person has towards their own appearance, often relating to body size, shape and attractiveness.

    Most of the studies we included were published in 2020 onwards. The majority were carried out in Western countries (such as the United States, the United Kingdom and Australia). Just under half of studies included participants of all genders. Interestingly, 44% of studies observed men exclusively, while only 7% included just women.

    Of the 45 studies, 29 looked at the impact of dating apps on mental health and wellbeing and 22 considered the impact on body image (some looked at both). Some studies examined differences between users and non-users of dating apps, while others looked at whether intensity of dating app use (how often they’re used, how many apps are used, and so on) makes a difference.

    More than 85% of studies (19 of 22) looking at body image found significant negative relationships between dating app use and body image. Just under half of studies (14 of 29) observed negative relationships with mental health and wellbeing.

    The studies noted links with problems including body dissatisfaction, disordered eating, depression, anxiety and low self-esteem.

    A man leaning against large windows of an apartment.
    Dating apps are becoming increasingly common. But could their use harm mental health? Rachata Teyparsit/Shutterstock

    It’s important to note our research has a few limitations. For example, almost all studies included in the review were cross-sectional – studies that analyse data at a particular point in time.

    This means researchers were unable to discern whether dating apps actually cause body image, mental health and wellbeing concerns over time, or whether there is simply a correlation. They can’t rule out that in some cases the relationship may go the other way, meaning poor mental health or body image increases a person’s likelihood of using dating apps.

    Also, the studies included in the review were mostly conducted in Western regions with predominantly white participants, limiting our ability to generalise the findings to all populations.

    Why are dating apps linked to poor body image and mental health?

    Despite these limitations, there are plausible reasons to expect there may be a link between dating apps and poorer body image, mental health and wellbeing.

    Like a lot of social media, dating apps are overwhelmingly image-centric, meaning they have an emphasis on pictures or videos. Dating app users are initially exposed primarily to photos when browsing, with information such as interests or hobbies accessible only after manually clicking through to profiles.

    Because of this, users often evaluate profiles based primarily on the photos attached. Even when a user does click through to another person’s profile, whether or not they “like” someone may still often be determined primarily on the basis of physical appearance.

    This emphasis on visual content on dating apps can, in turn, cause users to view their appearance as more important than who they are as a person. This process is called self-objectification.

    People who experience self-objectification are more likely to scrutinise their appearance, potentially leading to body dissatisfaction, body shame, or other issues pertaining to body image.

    A woman using a dating app.
    Dating apps are overwhelmingly image-centric. Studio Romantic/Shutterstock

    There could be several reasons why mental health and wellbeing may be impacted by dating apps, many of which may centre around rejection.

    Rejection can come in many forms on dating apps. It can be implied, such as having a lack of matches, or it can be explicit, such as discrimination or abuse. Users who encounter rejection frequently on dating apps may be more likely to experience poorer self-esteem, depressive symptoms or anxiety.

    And if rejection is perceived to be based on appearance, this could lead again to body image concerns.

    What’s more, the convenience and game-like nature of dating apps may lead people who could benefit from taking a break to keep swiping.

    What can app developers do? What can you do?

    Developers of dating apps should be seeking ways to protect users against these possible harms. This could, for example, include reducing the prominence of photos on user profiles, and increasing the moderation of discrimination and abuse on their platforms.

    The Australian government has developed a code of conduct – to be enforced from April 1 this year – to help moderate and reduce discrimination and abuse on online dating platforms. This is a positive step.

    Despite the possible negatives, research has also found dating apps can help build confidence and help users meet new people.

    If you use dating apps, my colleagues and I recommend choosing profile images you feel display your personality or interests, or photos with friends, rather than semi-clothed images and selfies. Engage in positive conversations with other users, and block and report anyone who is abusive or discriminatory.

    It’s also sensible to take breaks from the apps, particularly if you’re feeling overwhelmed or dejected.

    If this article has raised issues for you, or if you’re concerned about someone you know, call Lifeline on 13 11 14. The Butterfly Foundation provides support for eating disorders and body image issues, and can be reached on 1800 334 673.

    Zac Bowman, PhD Candidate, College of Education, Psychology & Social Work, Flinders University

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Can You Gain Muscle & Lose Fat At The Same Time?

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    It’s Q&A Day at 10almonds!

    Have a question or a request? We love to hear from you!

    In cases where we’ve already covered something, we might link to what we wrote before, but will always be happy to revisit any of our topics again in the future too—there’s always more to say!

    As ever: if the question/request can be answered briefly, we’ll do it here in our Q&A Thursday edition. If not, we’ll make a main feature of it shortly afterwards!

    So, no question/request too big or small 😎

    ❝Is it possible to lose fat and gain muscle at the same time, or do we need to focus on one and then the other, and if so, which order is best?❞

    Contrary to popular belief, you can do both simultaneously! However, it’s not as easy as doing just one or the other, which is why most bodybuilders, for example, have a “building phase” and a “cutting phase”.

    The reason it’s difficult is because of the diet. Growing muscle doesn’t just take protein and micronutrients; it takes energy as well, which must come from carbohydrates and/or fats. Therefore, it is tricky to eat enough to build muscle and to fuel the workouts that are required to build the muscle (you can’t hit the gym in a state of rabbit starvation* and expect to perform well at your workout), while at the same time not eating enough carbs/fats to have any excess to store as fat.

    *So-called because rabbit-meat is very lean, such that when during times of famine, European peasants tried to subsist off mostly rabbits, their health quickly plummeted for lack of energy. It’s also been called “salmon starvation”, apparently, for the same reason:

    How ancestral subsistence strategies solve salmon starvation and the “protein problem” of Pacific Rim resources

    In French it’s called “mal de caribou” (caribou sickness), by the way. But you get the idea: eat too much lean protein without enough carbs/fats, and woe shall befall.

    So, if you want to do both at once, you need to be incredibly on top of your macros, and the bad news is, only you (or a coach working directly with you) can work out what precise macros requirements your body has, because it depends on your body and your activities.

    The easier “half-way house”

    We will get to the “building phase” and “cutting phase” of bodybuilders, but first, here’s an option that’s very worthy of consideration, and it is: forget about your weight and just focus on health while incidentally doing regular resistance exercises and HIIT.

    What will happen if you do this (assuming a healthy balanced diet, nothing special and without counting anything, but we’re talking at least mostly whole-foods, and at least mostly plants; the Mediterranean diet is great for this, as it is for most things) is:

    • The dietary approach described will gradually improve your metabolic health if it wasn’t already good. If it was already good, it’ll likely just maintain it, rather than improve it.
    • The resistance exercises will, if engaged with seriously (it has to be difficult to do, or your muscles won’t have any reason to grow), gradually build muscle. This will be very gradual, because you’re not eating for bodybuilding, nor optimizing your general lifestyle for same. Historically many women have feared lifting weights because they don’t want to “look like a weightlifter”, but the kinds of bodies that word brings to mind are not the kind that happen by accident (especially for women, with our different hormones guiding our bodies to a different composition); it takes a lot of single-minded dedication to specifically optimize size gains, for a long time.
    • The high-intensity interval training (HIIT) will more rapidly improve your metabolic health, and unlike most forms of exercise, it will actually result in a gradual reduction of fat, if you have superfluous fat to lose. This is because whereas most forms of cardio exercise increase the heartrate for a while but then have a corresponding metabolic slump afterwards to make up for it, HIIT confuses the heart (in a good way) which results in it having to grow stronger, and not doing any compensatory metabolic slump:

    How To Do HIIT (Without Wrecking Your Body) ← as well as the “how to”, this also gives some of the science behind it, too

    This will, thus, result in gradual gain of muscle and loss of fat—or if you take it easier with the exercise, then you can easily settle into just maintaining your body composition as it is, but that wasn’t the question today.

    So, there you have it, that’s how to do both at once! Now, if you want more dramatic results, then more dramatic methods are called for:

    What bodybuilders (mostly) do

    Matters of genetic predisposition and commonplace use of steroids aside, here’s how bodybuilders get that “lots of muscle, no fat” figure:

    1. First, get into “moderate” shape if not already there.
    2. Bulk up: eat amounts of food that will seem unreasonable to a non-bodybuilder; eating 2x or even 3x the “recommended” daily calorie amount is common; focus is typically on getting adequate (for bodybuilding purposes) protein while also carb-loading for workouts and getting at least enough fats for fat-soluble vitamins to work. In the gym, focus on doing sets of very few reps with the heaviest weights one can safely lift, while doing minimal cardio, and also sleeping a lot (9–12hrs per day), which is essential because this is putting a huge strain on the body and it needs a chance to recover and rebuild.
    3. Cut down: maintain protein intake (to at least mostly maintain muscles) while keeping carbs and fats low, doing cardio work (HIIT is still ideal) and running a calorie deficit for a short while (there is no use in trying to maintain a long-term calorie deficit; your body will try to save you from starvation by storing any fat it can and slowing your metabolism).

    Phases 2 and 3 are then cycled, alternating every month, or every 6 weeks, or every 2 months or so, depending on personal preferences and scheduling considerations (bodybuilders will often have competitions they are working towards, so they need to time things to be at the end of a cutting phase to look their “best” by bodybuilder standards).

    Disclaimer: bodybuilding is complex, and can be ruinous to the health if practised inexpertly, because of its extreme nature. We don’t recommend serious bodybuilding per se in general, but if you are going to do it, please consult with a professional bodybuilding coach, and do not rely on a few paragraphs from us that are intended only to give the most basic overview of how bodybuilders can approach the “gain muscle, lose fat” problem.

    Want to know more?

    We’ve written on some related topics previously; here’s a three-part series:

    1. How To Lose Weight (Healthily!)
    2. How To Build Muscle (Healthily!)
    3. How To Gain Weight (Healthily!) ← this one’s specifically about gaining healthy levels of fat, for any who want/need that

    And also:

    Can We Do Fat Redistribution? ← yes we can, but there are caveats

    Take care!

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