Cold Medicines & Heart Health

In the wake of many decongestants disappearing from a lot of shelves after a common active ingredient being declared useless*, you may find yourself considering alternative decongestants at this time of year.

*In case you missed it:

Why Is Oral Phenylephrine on the Market After Compelling Evidence of Its Ineffectiveness as a Decongestant?

It doesn’t seem to be dangerous, by the way, just also not effective:

FDA Panel Says Common OTC Decongestant, Phenylephrine, Is Useless

Good for your nose, bad for your heart?

With products based on phenylephrine out of the running, products based on pseudoephedrine, a competing drug, are enjoying a surge in popularity.

Good news: pseudoephedrine works!

Bad news: pseudoephedrine works because it is a vasoconstrictor, and that vasoconstriction reduces nasal swelling. That same vasoconstriction also raises overall blood pressure, potentially dangerously, depending on an assortment of other conditions you might have.

Further reading: Can decongestants spike your blood pressure? What to know about hypertension and cold medicine

Who’s at risk?

The warning label, unread by many, reads:

❝Do not use this product if you have heart disease, high blood pressure, thyroid disease, diabetes, or difficulty in urination due to enlargement of the prostate gland, unless directed by a doctor❞

Source: Harvard Health | Don’t let decongestants squeeze your heart

What are the other options?

The same source as above recommends antihistamines as an option to be considered, citing:

❝Antihistamines such as […] cetirizine (Zyrtec) and loratadine (Claritin) can help with a stuffy nose and are safe for the heart.❞

But we’d be remiss not to mention drug-free options too, for example:

• Saline rinse with a neti pot or similar
• Use of a humidifier in your house/room
• Steam inhalation, with or without eucalyptus etc

See also: Inhaled Eucalyptus’s Immunomodulatory and Antimicrobial Effects

Take care!

Eggs: All Things In Moderation?

We asked you for your (health-related) opinion on eggs. We specified that, for the sake of simplicity, let’s say that they are from happy healthy backyard hens who enjoy a good diet.

Apparently this one wasn’t as controversial as it might have been! We (for myth-busting purposes) try to pick something polarizing and sometimes even contentious for our Friday editions, and pick apart what science lies underneath public perceptions.

However, more than half (in fact, 60%) of the subscribers who voted in the poll voted for “Eggs are nutritionally beneficial as part of a balanced diet”, which very moderate statement is indeed pretty much the global scientific consensus.

Still, we’ve a main feature to write, so let’s look at the science, and what the other 40% had in mind:

Eggs are ruinous to health, especially cardiometabolic health: True or False?

False, per best current science, anyway!

Scientific consensus has changed over the years. We learned about cholesterol, then we learned about different types of cholesterol, and now we’ve even learned about in some instances even elevated levels of “bad” cholesterol aren’t necessarily a cause of cardiometabolic disorders so much as a symptom—especially in women.

Not to derail this main feature about eggs (rather than just cholesterol), but for those who missed it, this is actually really interesting: basically, research (pertaining to the use of statins) has found that in women, higher LDL levels aren’t anywhere near the same kind of risk factor as they are for men, and thus may mean that statins (whose main job is reducing LDL) may be much less helpful for women than for men, and more likely to cause unwanted serious side effects in women.

Check out our previous main feature about this: Statins: His & Hers?

But, for back on topic, several large studies (totalling 177,000 people in long-term studies in 50 countries) found:

❝Results from the three cohorts and from the updated meta-analysis show that moderate egg consumption (up to one egg per day) is not associated with cardiovascular disease risk overall, and is associated with potentially lower cardiovascular disease risk in Asian populations.❞

Source: Egg consumption and risk of cardiovascular disease: three large prospective US cohort studies, systematic review, and updated meta-analysis

Egg whites are healthy (protein); egg yolks are not (cholesterol): True or False?

True and False, respectively. That is to say, egg whites are healthy (protein), and egg yolks are also healthy (many nutrients).

We talked a bit already about cholesterol, so we’ll not rehash that here. As to the rest:

Eggs are one of the most nutritionally dense foods around. After all, they have everything required to allow a cluster of cells to become a whole baby chick. That’s a lot of body-building!

They’re even more nutritionally heavy-hitters if you get omega-3 enriched eggs, which means the hens were fed extra omega-3, usually in the form of flax seeds.

Also, free-range is better healthwise than others. Do bear in mind that unless they really are from your backyard, or a neighbor’s, chances are that the reality is not what the advertising depicts, though. There are industry minimum standards to be able to advertise as “free-range”, and those standards are a) quite low b) often ignored, because an occasional fine is cheaper than maintaining good conditions.

So if you can look after your own hens, or get them from somewhere that you can see for yourself how they are looked after, so much the better!

Check out the differences side-by-side, though:

Pastured vs Omega-3 vs “Conventional” Eggs: What’s the Difference?

Stallone-style 12-egg smoothies are healthy: True or False?

False, at least if taken with any regularity. One can indeed have too much of a good thing.

So, what’s the “right amount” to eat?

It may vary depending on individual factors (including age and ethnicity), but a good average, according to science, is to keep it to 3 eggs or fewer per day. There are a lot of studies, but we only have so much room here, so we’ll pick one. Its findings are representative of (and in keeping with) the many other studies we looked at, so this seems uncontroversial scientifically:

❝Intake of 1 egg/d was sufficient to increase HDL function and large-LDL particle concentration; however, intake of 2-3 eggs/d supported greater improvements in HDL function as well as increased plasma carotenoids. Overall, intake of ≤3 eggs/d favored a less atherogenic LDL particle profile, improved HDL function, and increased plasma antioxidants in young, healthy adults.❞

Source: Intake of up to 3 Eggs per Day Is Associated with Changes in HDL Function and Increased Plasma Antioxidants in Healthy, Young Adults

Enjoy!