Eat to Beat Disease – by Dr. William Li

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Dr. William Li asks the important question: is your diet feeding disease, or defeating it?

Because everything we put in our bodies makes our health just a little better—or just a little worse. Ok, sometimes a lot worse.

But for most people, when it comes to diet, it’s a death of a thousand cuts of unhealthy food. And that’s what he looks to fix with this book.

The good news: Dr. Li (while not advocating for unhealthy eating, of course), focuses less on what to restrict, and more on what to include. This book covers hundreds of such healthy foods, and ideas (practical, useful ones!) on incorporating them daily, including dozens of recipes.

He mainly looks at five ways our food can help us with…

  1. Angiogenesis (blood vessel replacement)
  2. Regeneration (of various bodily organs and systems)
  3. Microbiome health (and all of its knock-on effects)
  4. DNA protection (and thus slower cellular aging)
  5. Immunity (defending the body while also reducing autoimmune problems)

The style is simple and explanatory; Dr. Li is a great educator. Reading this isn’t a difficult read, but you’ll come out of it feeling like you just did a short course in health science.

Bottom line: if you’d like an easy way to improve your health in an ongoing and sustainable way, then this book can help you do just that.

Click here to check out Eat To Beat Disease, and eat to beat disease!

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  • The weight loss drug Mounjaro has been approved to treat sleep apnoea. How does it work?

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Last week, Australia’s Therapeutic Goods Administration (TGA) approved the weight-loss drug Mounjaro to treat sleep apnoea, a condition in which breathing stops and starts repeatedly during sleep.

    The TGA has indicated Mounjaro can be used to treat moderate to severe obstructive sleep apnoea in adults with obesity (a body-mass index of 30 or above).

    The United States Food and Drug Administration approved the same drug for sleep apnoea last year.

    So how could this drug, most commonly used for weight management and conditions such as type 2 diabetes, help people with sleep apnoea?

    coldsnowstorm/Getty Images

    What is sleep apnoea?

    Obstructive sleep apnoea is a common sleep disorder affecting almost 1 billion people worldwide. It’s characterised by repeated closures of the airway during sleep (called “apnoeas”). These can be partial or complete closures, meaning breathing can become shallow or stop completely.

    As well as causing fragmented sleep, repeated collapse of the airway disrupts oxygen flow to the body. This strains the heart and contributes to an increased risk of cardiovascular and metabolic complications such as diabetes, high blood pressure and stroke.

    One of the key risk factors for obstructive sleep apnoea is obesity. About 80% of people with the condition live with obesity. In fact, obesity and sleep apnoea share a bidirectional relationship, with obesity increasing the risk of developing sleep apnoea, and vice versa.

    Obesity increases the risk of sleep apnoea by adding fat around the neck, which narrows the airway and impacts breathing during sleep.

    In turn, sleep apnoea can contribute to weight gain by disrupting hormones that regulate hunger (ghrelin) and fullness signals (leptin). Fatigue also contributes, making it harder to maintain a healthy weight and easier to gain weight over time, creating a vicious cycle where each condition worsens the other.

    Weight loss is a key part of treating sleep apnoea. It helps reduce the severity of symptoms and also lowers the risk of heart disease and other health problems which may arise as a result of sleep apnoea. However, achieving and sustaining weight loss through lifestyle changes is often challenging.

    A continuous positive airway pressure (CPAP) machine is generally the first-line therapy for managing moderate to severe sleep apnoea. It delivers a steady stream of pressurised air through a mask to keep the airway open during sleep, which stabilises breathing and improves sleep quality.

    Despite being an effective treatment, many people find the CPAP machine uncomfortable, unattractive or hard to use regularly. This can mean people don’t always stick to it.

    Given the significant human and economic costs of sleep apnoea it’s pertinent to keep exploring new prevention and management strategies.

    A man sleeps with a CPAP machine.
    CPAP machines are currently the first line of treatment for moderate to severe sleep apnoea. Anastasija Vujic/Shutterstock

    What is Mounjaro, and how could it help people with sleep apnoea?

    Mounjaro is the brand name of a drug called tirzepatide. Elsewhere, it goes by other brand names, such as Zepbound.

    Tirzepatide works by mimicking two hormone receptors in the gut, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP).

    These two hormones play a key role in regulating our appetite, food intake and blood sugar levels. GLP-1 and GIP are released naturally in the body when we eat, but by mimicking their effects, tirzepatide allows people to feel fuller with smaller meals.

    If a person is eating less overall, this can lead to weight loss.

    In a study of 469 people with obesity and moderate to severe obstructive sleep apnoea, one year of tirzepatide treatment was associated with up to a 60% reduction in sleep apnoea severity. This is compared to a 3% reduction in people receiving a placebo.

    In addition, evidence shows tirzepatide is associated with improvements in several key health indicators, including reduced systemic inflammation, enhanced insulin sensitivity and lower blood pressure. Changes such as these may improve respiratory function and help protect against cardiovascular and metabolic complications, which are common outcomes of untreated sleep apnoea.

    Are there any side effects?

    While Mounjaro could be helpful for people with sleep apnoea, gastrointestinal side effects are relatively common with this medication. These can include nausea, vomiting, diarrhoea, constipation and loss of appetite. These side effects typically go away as the person gets used to the medication.

    Some patients have also reported gallbladder problems.

    Despite these concerns, there is an interest in Mounjaro as sleep apnoea treatment as it provides the first pharmaceutical option for a condition that has traditionally relied on mechanical treatments such as CPAP machines.

    That said, it’s important to note Mounjaro is indicated for use in patients with obesity, and not all patients with sleep apnoea are overweight or obese.

    In some people of a healthy weight, narrow skeletal structure or upper airway anatomy, such as larger soft palates (which can reduce airway space and make it more prone to collapse during sleep), could contribute to obstructive sleep apnoea.

    For those patients, non-pharmacological treatment options such as mandibular advancement devices (oral appliances that move the lower jaw forward and keep the airway open) and upper airway surgery may be needed to effectively manage the condition.

    Mounjaro is given as a weekly injection. In Australia, Mounjaro is not currently subsidised under the Pharmaceutical Benefits Scheme and is available only by private prescription, with prices beginning at around A$395 per month. The significant out-of-pocket cost will limit access to Mounjaro for many patients.

    Mounjaro’s approval for the treatment of sleep apnoea may offer new hope for many people. But considering the diversity in patient presentations and limited data from large population studies, it’s too early to say whether this will transform sleep apnoea care in Australia.

    Yaqoot Fatima, Professor of Sleep Health, University of the Sunshine Coast and Nisreen Aouira, Research Program Manager, Thompson Institute, University of the Sunshine Coast

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • Altered Traits – by Dr. Daniel Goleman & Dr. Richard Davidson

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    We know that meditation helps people to relax, but what more than that?This book explores the available science.

    We say “explore the available science”, but it’d be remiss of us not to note that the authors have also expanded the available science, conducting research in their own lab.

    From stress tests and EEGs to attention tests and fMRIs, this book looks at the hard science of what different kinds of meditation do to the brain. Not just in terms of brain state, either, but gradual cumulative anatomical changes, too. Powerful stuff!

    The style is very pop-science in presentation, easily comprehensible to all. Be aware though that this is an “if this, then that” book of science, not a how-to manual. If you want to learn to meditate, this isn’t the book for that.

    Bottom line: if you’d like to understand more about how different kinds of meditation affect the brain differently, this is the book for you.

    Click here to check out Altered Traits, and alter yours!

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  • Do Breathe – by Michael Williams

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Have you ever felt you could get everything in your life in order, if you could just get a little breathing room first?

    Notwithstanding the title, this is mostly not a book about breathing exercises. It does cover that too, but there’s a lot more.

    The author’s advices draw from a variety of high quality sources. Well-read readers will certainly recognise sections that are straight from David Allen’s “Getting Things Done”, and Mihaly Czikszentmihalyi’s “Flow”, for example, as well as Francesco Cirillo’s “Pomodoro Technique”, and James Clear’s “Atomic Habits”.

    We also learn about how even simple yoga can help us, and good sleep, and a healthy diet.

    In short, if you’ve been reading 10almonds for a while, you might not actually learn much new! But it’s very nice to have all these things in one book, for sure, and it’s a pleasant, easy read too.

    Bottom line: if you’d like to streamline your life and not have to buy a whole stack of different books to do it, this book is a great composite that will enable you to get the job done efficiently.

    Click here to check out Do Breathe, and simplify your life!

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  • Why Diets Make Us Fat – by Dr. Sandra Aamodt

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    It’s well-known that crash-dieting doesn’t work. Restrictive diets will achieve short-term weight loss, but it’ll come back later. In the long term, weight creeps slowly upwards. Why?

    Dr. Sandra Aamodt explores the science and sociology behind this phenomenon, and offers an evidence-based alternative.

    A lot of the book is given over to explanations of what is typically going wrong—that is the title of the book, after all. From metabolic starvation responses to genetics to the negative feedback loop of poor body image, there’s a lot to address.

    However, what alternative does she propose?

    The book takes us on a shift away from focusing on the numbers on the scale, and more on building consistent healthy habits. It might not feel like it if you desperately want to lose weight, but it’s better to have healthy habits at any weight, than to have a wreck of physical and mental health for the sake of a lower body mass.

    Dr. Aamodt lays out a plan for shifting perspectives, building health, and letting weight loss come by itself—as a side effect, not a goal.

    In fact, as she argues (in agreement with the best current science, science that we’ve covered before at 10almonds, for that matter), that over a certain age, people in the “overweight” category of BMI have a reduced mortality risk compared to those in the “healthy weight” category. It really underlines how there’s no point in making oneself miserably unhealthy with the end goal of having a lighter coffin—and getting it sooner.

    Bottom line: will this book make you hit those glossy-magazine weight goals by your next vacation? Quite possibly not, but it will set you up for actually healthier living, for life, at any weight.

    Click here to check out Why Diets Make Us Fat, and live healthier and better!

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  • The Anatomy of Anxiety – by Dr. Ellen Vora

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    The author, a holistic psychiatrist (notably, she is a psychiatrist and also a yoga teacher, which does factor in), takes a functional approach to mental health, and seeks to treat the cause where possible, rather than merely the symptom. That might not sound groundbreaking, but honestly, the vast majority of psychiatrists in particular do take a “here’s a prescription for Diralisin, and let’s schedule an appointment for two months from now to see how it’s going” approach, so this is refreshing.

    You know what else is refreshing? That she acknowledges the difference between “true” and “false” anxiety, that is to say: actually there are many legitimate reasons to be anxious, and those can’t be CBT’d away with a flowchart that asks you to challenge your automatic thoughts, because what if you examine the threat and conclude from the evidence that “no, this one’s a real threat; things genuinely are bad”?

    However, that doesn’t mean to say that nothing can be done for our mental health in those regards; indeed, there’s plenty to be done, both in terms of cognitive restructuring (including, but not limited to, radical acceptance and reframing) and in terms of things that are more of the variety: “this is not related to that at all, but it’ll make you feel better, so hey, use what works”.

    That’s where a lot of her holistic approach comes in. Having a shower or going for a nature walk or eating some fruit will probably not eliminate an existential threat, but the existential threat is easier to face when refreshed and nourished, for example.

    She also talks about what things to hold onto and what to let go (and how to decide the difference for yourself), how to make your social connections anxiolytic instead of anxiogenic (i.e., they ease your anxiety rather than increase it), and how to stay informed in a world on fire without burning out about it.

    The style is high-end pop-science with a lot of references, and its information-density does not stop it from also being very readable.

    Bottom line: if you suffer from anxiety and would like to not do so, this book is a treasure-trove of evidence-based ways to address that and feel better, healthily, while still acknowledging reality as it is rather than as you’d prefer it to be.

    Click here to check out The Anatomy Of Anxiety, and ease yours with a sound, scientific approach!

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  • Unprocessed – by Kimberly Wilson

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    First, what this is not: hundreds of pages to say “eat less processed food”. That is, of course, also advisable (and indeed, is advised in the book too), but there’s a lot more going on here too.

    Though not a doctor, the author is a psychologist who brings a lot of data to the table, especially when it comes to the neurophysiology at hand, what forgotten micronutrients many people are lacking, and what trends in society worsen these deficiencies in the population at large.

    If you only care about the broadest of take-away advice, it is: eat a diet that’s mostly minimally processed plants and some oily fish, watch out for certain deficiencies in particular, and increase dietary intake of them where necessary (with taking supplements as a respectable next-best remedy).

    On which note, a point of criticism is that there’s some incorrect information about veganism and brain health; she mentions that DHA is only found in fish (in fact, fish get it from algae, which has it, and is the basis of many vegan omega-3 supplements), and the B12 is found only in animals (also found in yeast, which is not an animal, as well as various bacteria in soil, and farm animals get their B12 from supplements these days anyway, so it is arguable that we could keep things simpler by just cutting out the middlecow).

    However, the strength of this book really is in the delivery of understanding about why certain things matter. If you’re told “such-and-such is good for the brain”, you’ll up your intake for 1–60 days, depending on whether you bought a supermarket item or ordered a batch of supplements. And then you’ll forget, until 6–12 months later, and you’ll do it again. On the other hand, if you understand how something is good or bad for the brain, what it does (for good or ill) on a cellular level, the chemistry and neurophysiology at hand, you’ll make new habits for life.

    The style is middle-range pop-science; by this we mean there are tables of data and some long words that are difficult to pronounce, but also it’s not just hard science throughout—there’s (as one might expect from an author who is a psychologist) a lot about the psychology and sociology of why many people make poor dietary decisions, and the things governments often do (or omit doing) that affect this adversely—and how we can avoid those traps as individuals (unless we be incarcerated or such).

    As an aside, the author is British, so governmental examples are mostly UK-based, but it doesn’t take a lot to mentally measure that against what the governments of, for example, the US or Canada do the same or differently.

    Bottom line: there’s a lot of great information about brain health here; the strongest parts are whether the author stays within her field (psychology encompasses such diverse topics as neurophysiology and aspects of sociology, but not microbiology, for example). If you want to learn about the physiology of brain health and enjoy quite a sociopolitical ride along the way, this one’s a good one for that.

    Click here to check out Unprocessed, and make the best choices for you!

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