Five Advance Warnings of Multiple Sclerosis

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Five Advance Warnings of Multiple Sclerosis

First things first, a quick check-in with regard to how much you know about multiple sclerosis (MS):

  • Do you know what causes it?
  • Do you know how it happens?
  • Do you know how it can be fixed?

If your answer to the above questions is “no”, then take solace in the fact that modern science doesn’t know either.

What we do know is that it’s an autoimmune condition, and that it results in the degradation of myelin, the “insulator” of nerves, in the central nervous system.

  • How exactly this is brought about remains unclear, though there are several leading hypotheses including autoimmune attack of myelin itself, or disruption to the production of myelin.
  • Treatments look to reduce/mitigate inflammation, and/or treat other symptoms (which are many and various) on an as-needed basis.

If you’re wondering about the prognosis after diagnosis, the scientific consensus on that is also “we don’t know”:

Read: Personalized medicine in multiple sclerosis: hope or reality?

this paper, like every other one we considered putting in that spot, concludes with basically begging for research to be done to identify biomarkers in a useful fashion that could help classify many distinct forms of MS, rather than the current “you have MS, but who knows what that will mean for you personally because it’s so varied” approach.

The Five Advance Warning Signs

Something we do know! First, we’ll quote directly the researchers’ conclusion:

❝We identified 5 health conditions associated with subsequent MS diagnosis, which may be considered not only prodromal but also early-stage symptoms.

However, these health conditions overlap with prodrome of two other autoimmune diseases, hence they lack specificity to MS.❞

So, these things are a warning, five alarm bells, but not necessarily diagnostic criteria.

Without further ado, the five things are:

  1. depression
  2. sexual disorders
  3. constipation
  4. cystitis
  5. urinary tract infections

❝This association was sufficiently robust at the statistical level for us to state that these are early clinical warning signs, probably related to damage to the nervous system, in patients who will later be diagnosed with multiple sclerosis.

The overrepresentation of these symptoms persisted and even increased over the five years after diagnosis.❞

~ Dr. Céline Louapre

Read the paper for yourself:

Association Between Diseases and Symptoms Diagnosed in Primary Care and the Subsequent Specific Risk of Multiple Sclerosis

Hot off the press! Published only yesterday!

Want to know more about MS?

Here’s a very comprehensive guide:

National clinical guideline for diagnosis and management of multiple sclerosis

Take care!

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    Dr. Doug Weiss, a physiotherapist (and thus: a doctor of physical therapy), has advice on how and why to increase blood flow and circulation in your legs, keeping yourself healthier for longer and avoiding a lot of potential unpleasantries.

    The exercises

    The exercises here are not complex; they are as follows, and he suggests 3 sets of 10 reps of each, daily:

    • Sitting ankle pumps: sitting on a chair or the edge of a bed, lift the toes up, then heels up, squeezing the muscles.
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    For visuals on these, and more details including the specific benefits of each, enjoy:

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  • The Wim Hof Method – by Wim Hof

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    In Wednesday’s main feature, we wrote about the Wim Hof Method, and/but only scratched the surface. Such is the downside of being a super-condensed newsletter! However, it does give us the opportunity to feature the book:

    The Wim Hof Method is definitely loudly trumpeted as “up there” with Atomic Habits or How Not To Die in the category of “life-changing” books. Why?

    Firstly, it’s a very motivational book. Hof is a big proponent of the notion “if you think you can or you think you can’t, you’re right” idea, practises what he preaches, and makes clear he’s not special.

    Secondly, it’s backed up with science. While it’s not a science-heavy book and that’s not the main focus, there are references to studies. Where physiological explanations are given for how certain things work, those explanations are sound. There’s no pseudoscience here, which is especially important for a book of this genre!

    What does the book have that our article didn’t? A good few things:

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    Bottom line: this book offers benefits that stretch into many areas of life, from some simple habits that can be built.

    Pick up your copy of The Wim Hof Method from Amazon today!

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  • Healthy Homemade Flatbreads

    10almonds is reader-supported. We may, at no cost to you, receive a portion of sales if you purchase a product through a link in this article.

    Our recipes sometimes call for the use of flatbreads, or suggest serving with flatbreads. But we want you to be able to have healthy homemade ones! So here’s a very quick and easy recipe. You’ll probably need to order some of the ingredients in, but it’s worth it, and then if you keep a stock of the ingredients, you can whip these up in minutes anytime you want them.

    You will need

    • 1 cup garbanzo bean flour, plus more for dusting
    • 1 cup quinoa flour
    • 2 tbsp ground/milled flaxseed
    • 1 tbsp baking powder
    • 1 tbsp extra virgin olive oil, plus more for the pan
    • ½ tsp MSG, or 1 tsp low-sodium salt, with MSG being the healthier and preferable option
    • ½ tsp onion powder
    • ½ tsp garlic powder
    • ½ tsp dried cumin
    • ½ tsp dried thyme

    Method

    (we suggest you read everything at least once before doing anything)

    1) Mix the flaxseed with ⅓ cup of water and set aside for at least 5 minutes.

    2) Combine the rest of the ingredients in a big bowl, plus the flax mixtures we just made, and an extra ½ cup of water. Knead this into a dough, adding a touch more water if it becomes necessary, but be sparing with it.

    3) Divide the dough into 6 equal portions, shaping each into a ball. Dust a clean surface with the extra garbanzo bean flour, and roll each dough ball into in a thin 6″ circle.

    4) Heat a skillet and add some olive oil for frying; when hot enough, place a dough disk in the pan and cook for a few minutes on each side until golden brown. Repeat with the other 5.

    5) Serve! If you’re looking for a perfect accompaniment to these, try our Hero Homemade Hummus

    Enjoy!

    Want to learn more?

    For those interested in some of the science of what we have going on today:

    Take care!

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    But, before diving into the exercises, it’s essential to gauge your current flexibility. A basic hip flexor stretch serves as a pre-test.

    Note: the goal here isn’t to stretch, but rather to feel how tight you are.

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    Note: this video focuses on chronic psoas issues. If you have sore psoas from a muscular workout, you may want to read our piece on speeding up muscle recovery.

    Is That All?

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    Next, the tennis ball technique zeroes in on specific tight spots in the psoas. By lying on the ball and adjusting its position around the hip area, you can likely release some deeply held tension.

    Additionally, some of our readers advocate for acupuncture for psoas relief – we’ve done an acupuncture myth-busting article here for reference.

    Other Sources

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    How did you find that video? If you’ve discovered any great videos yourself that you’d like to share with fellow 10almonds readers, then please do email them to us!

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    Have a question or a request? You can always hit “reply” to any of our emails, or use the feedback widget at the bottom!

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    ❝Would be interested in your views about “reading yourself to sleep”. I find that current affairs magazines and even modern novels do exactly the opposite. But Dickens – ones like David Copperfield and Great Expectations – I find wonderfully effective. It’s like entering a parallel universe where none of your own concerns matter. Any thoughts on the science that may explain this?!❞

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    • General advice is to not do activities besides sleep (and sex) in bed

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    Enjoy!

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